Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.4.1.2 (
glutamate dehydrogenase
)
4,380
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Blood alpha-fetoprotein, carcinoembyronic antigen, CA-19-9, alkaline phosphatase, gamma-glutamyltranspeptidase, alanine aminotransferase, aspartate aminotransferase, sorbitol dehydrogenase,
glutamate dehydrogenase
, hemoglobin and red cell sedimentation rate were measured in patients with stages III and IV gastric carcinoma and patients with benign diseases of the stomach. Alanine aminotransferase, sorbitol dehydrogenase and
glutamate dehydrogenase
were found diagnostically not informative in gastric carcinoma stages III and IV. A complex of measurements of alpha-fetoprotein, alkaline phosphatase, gamma-glutamyl transpeptidase and aspartate aminotransferase detected gastric carcinoma metastases to the liver in 84.6% of cases as against 61.5% detected by measurements of alpha-fetoprotein alone. A complex of measurements of
carcinoembryonic antigen
, CA-19-9, alkaline phosphatase, gamma-glutamyl transpeptidase, aspartate aminotransferase helped differentiate between gastric carcinoma stages III and IV. A complex of measurements of
carcinoembryonic antigen
, CA-19-9, alkaline phosphatase, gamma-glutamyl transpeptidase, aspartate aminotransferase, hemoglobin, and red cell sedimentation rate improved the diagnostic sensitivity in detection of gastric carcinoma stages III and IV to 70.8 and 100%, respectively.
...
PMID:[Laboratory tests in the diagnosis of stomach cancer]. 800 Jul 94
This work has looked to explore an innovative and powerful visible fluorescence immunoassay method through wet NH
3
-triggered structural change of NH
2
-MIL-125(Ti) impregnated on paper for the detection of
carcinoembryonic antigen
(
CEA
). Gold nanoparticles heavily functionalized with
glutamate dehydrogenase
(
GDH
) and secondary antibody were used for generation of wet NH
3
with a sandwiched immunoassay format. Paper-based analytical device (PAD) coated with NH
2
-MIL-125(Ti) exhibited good visible fluorescence intensity through wet NH
3
-triggeried structural change with high accuracy and reproducibility. Moreover, NH
2
-MIL-125(Ti)-based PAD displayed two visual modes of fluorescence color and physical color with the naked eye and allowed the detection of
CEA
at a concentration as low as 0.041 ng mL
-1
. Importantly, the PAD-based assay provides promise for use in the mass production of miniaturized devices and opens new opportunities for protein diagnostics and biosecurity.
...
PMID:Wet NH
3
-Triggered NH
2
-MIL-125(Ti) Structural Switch for Visible Fluorescence Immunoassay Impregnated on Paper. 3046 75
