Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.4.1.2 (glutamate dehydrogenase)
 4,380 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In the human saliva (oral fluid), the activity of glutamate dehydrogenase tends to decrease in gingivitis and diminishes in periodontitis. That of gamma-glutamyl transpeptidase and creatine kinase increases in gingivitis. In periodontitis, their activity is higher than that in gingivitis. The above changes in enzymatic activities reflect metabolic changes in the gingiva and periodontium in inflammation. The saliva from the salivary ducts shows no activity of the above enzymes. They enter the mixed saliva (oral fluid) together with epithelial and other oral tissue cells, with leukocytes and microbes which manifold in gingivitis.
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PMID:[Activity of glutamate dehydrogenase, gamma-glutamyltranspeptidase and creatine kinase in saliva in gingivitis]. 908 17