Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.3.99.3 (acyl-CoA dehydrogenase)
 1,425 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
acyl-CoA dehydrogenase 754
medium-chain acyl-CoA dehydrogenase 354
long-chain acyl-CoA dehydrogenase 217
Mol 127
flavoprotein 122
Sep 121
FAD 102
acyl-CoA oxidase 75
short-chain acyl-CoA dehydrogenase 72
citrate synthase 65
peroxisome proliferator-activated receptor 53
3-hydroxyacyl-CoA dehydrogenase 52
carnitine palmitoyltransferase 51
insulin 48
long chain 48
ATP 47
enoyl-CoA hydratase 46
MCAD 39
C10 30
acyl-CoA synthetase 27
lactate dehydrogenase 27
very-long-chain acyl-CoA dehydrogenase 26
fatty acid synthase 26
isovaleryl-CoA dehydrogenase 24
3-ketoacyl-CoA thiolase 24
PGC 23
creatine kinase 23
peroxisome proliferator-activated receptor gamma 23
long chain acyl-CoA dehydrogenase 22
NADH 22
C18 21
ACADM 20
Pseudomonas 20
SCAD 20
acetyl-CoA carboxylase 19
ETFDH 19
ubiquinone 19
reductase 19
Medium-chain acyl-CoA dehydrogenase 18
hexokinase 18
oxidoreductase 18
VLCAD 17
NAD 17
PPAR 17
ETF 17
ADP 17
glutaryl-CoA dehydrogenase 17
CPT 16
lipoprotein lipase 16
pyruvate dehydrogenase 16
polypeptide 16
nuclear receptor 16
catalase 16
carnitine palmitoyltransferase I 15
CPT II 15
LCAD 15
AMP-activated protein kinase 14
UCP3 14
electron transfer flavoprotein-ubiquinone oxidoreductase 13
ATP synthase 13
CD36 13
superoxide dismutase 13
NMR 12
lipase 12
phosphofructokinase 12
She 12
peroxisome proliferator-activated receptor alpha 12
cytochrome P450 12
leptin 11
UCP2 11
HAD 11
ETFA 10
ATPase 10
GSH 10
cytochrome c oxidase 10
ETFB 10
2,4-dienoyl-CoA reductase 9
ACADVL 9
NAD+ 9
transcriptional regulator 9
uncoupling protein 9
adiponectin 9
isobutyryl-CoA dehydrogenase 9
FMN 9
TCA 9
biotinidase 9
carnitine palmitoyltransferase 1 9
L-3-hydroxyacyl-CoA dehydrogenase 8
fatty acid binding protein 8
microsomal 8
uncoupling protein 1 8
aldehyde dehydrogenase 8
crotonase 8
ACAD9 8
AMP 8
sterol regulatory element-binding protein 8
glucose-6-phosphate dehydrogenase 8
PPAR-alpha 7
PGC-1 7
AMPK 7
cytochrome c 7
CPT2 7
fatty acid translocase 7
TOF 7
ACADSB 7
NADPH 7
glucose transporter 7
malate dehydrogenase 7
hSCAD 7
cardiac muscle 7
phosphoenolpyruvate carboxykinase 6
diacylglycerol acyltransferase 6
SDS 6
glucagon 6
NADH dehydrogenase 6
fused 6
SOD 6
GLUT4 6
myosin heavy chain 6
collagen 6
pyruvate dehydrogenase kinase 4 6
CO2 6
isocitrate dehydrogenase 6
pyruvate carboxylase 6
pyruvate kinase 6
estrogen-related receptor alpha 6
ESI 6
LL) 6
membrane-bound 6
natriuretic peptide 6
gut 5
membrane protein 5
Peroxisome proliferator-activated receptor 5
beta-ketothiolase 5
MAD 5
MRI 5
ROS 5
inducible nitric oxide synthase 5
HMG-CoA synthase 5
aconitase 5
carnitine acetyltransferase 5
perilipin 5
SREBP-1 5
glutathione reductase 5
Hsp60 5
C15 5
carnitine palmitoyltransferase 1A 5
acyl-CoA dehydrogenase 9 5
FLAD1 5
CPT I 5
epididymal 5
pyruvate dehydrogenase kinase 5
apoE 5
albumin 5
GA2 5
hormone-sensitive lipase 5
myosin 5
SIRT3 5
nuclear hormone receptor 5
heat shock protein 5
more...
Disease
hypoglycemia 114
MCAD deficiency 90
cardiomyopathy 58
myopathy 50
phenylketonuria 37
obesity 34
glutaric aciduria 33
fatty liver 33
Reye's syndrome 29
encephalopathy 27
heart failure 25
metabolic disorder 25
sudden infant death syndrome 23
cold 19
diabetes 19
IVA 18
coma 18
methylmalonic acidemia 17
cystic fibrosis 16
Reye 16
propionic acidemia 15
maple syrup urine disease 15
Mycobacterium 15
homocystinuria 12
tumor 12
malnutrition 12
developmental delay 12
hypertension 11
cancer 10
tuberculosis 10
hepatocellular carcinoma 10
EMA 10
GSH 10
congenital hypothyroidism 10
enzyme deficiency 9
riboflavin deficiency 8
congenital adrenal hyperplasia 8
dilated cardiomyopathy 8
genetic disorder 7
myocardial infarction 7
lipidosis 7
lactic acidosis 7
glycogen storage disease 7
protein deficiency 7
metabolic syndrome 7
depression 7
hyperinsulinemia 7
Zellweger syndrome 7
epilepsy 7
SDS 6
hypertrophic cardiomyopathy 6
neuroblastoma 6
alcoholic fatty liver 6
Brown 6
galactosemia 6
type 2 diabetes 6
respiratory failure 5
dehydration 5
breast cancer 5
ketosis 5
retinopathy 5
ventricular hypertrophy 5
mitochondrial disease 5
AMD 5
nephrotic syndrome 4
neuropathy 4
mole 4
liver disease 4
myocardial ischemia 4
failure to thrive 4
mole 4
peripheral neuropathy 4
hyperphenylalaninemia 4
sickle cell disease 4
hyperglycemia 4
infectious diseases 4
McArdle's disease 4
pericardial effusion 4
ornithine transcarbamylase deficiency 4
influenza 4
tyrosinemia 3
pancreatic cancer 3
Evans 3
hyperlipidemia 3
fits 3
tumorigenesis 3
stroke 3
heart disease 3
PHA 3
virus infection 3
ischemia 3
mental retardation 3
citrullinemia 3
ALD 3
varicocele 3
Leigh syndrome 3
Nonalcoholic fatty liver 3
mental retardation 3
Forbes 3
glucose intolerance 2
confusion 2
renal insufficiency 2
atherosclerosis 2
renal failure 2
NBS 2
Fatty acid oxidation defects 2
hepatitis 2
diabetic cardiomyopathy 2
infertility 2
SCD 2
tumor progression 2
blindness 2
Moore 2
prostate cancer 2
pediatric disorder 2
congestive heart failure 2
glycinuria 2
acute renal failure 2
renal disease 2
lipid disorder 2
mucopolysaccharidosis 2
NAME 2
developmental disabilities 2
prolapse 2
muscular dystrophy 2
proteinuria 2
MCD 2
sepsis 2
rash 2
GA I 2
cirrhosis 2
cerebral palsy 2
hypoglycemic coma 2
neuromuscular disorder 2
Friedreich's ataxia 2
HMG-CoA lyase deficiency 2
Inborn errors of metabolism 2
leukodystrophy 2
GSD I 2
attention deficit disorder 2
neuronal ceroid lipofuscinosis 2
type 1 diabetes 2
hemoglobinopathies 2
glioma 2
MRS 2
sepsis 2
vitamin B12 deficiency 2
FAS 2
Alzheimer's disease 2
suicide 2
long QT syndrome 2
diabetic retinopathy 1
coronary occlusion 1
acute myocardial infarction 1
tyrosinosis 1
bipolar disorder 1
cytomegalovirus 1
Hypertrophic cardiomyopathy 1
chondrodysplasia 1
Crohn's disease 1
more...
Symptom
weakness 39
vomiting 21
hypotonia 19
seizures 18
hepatomegaly 16
starvation 15
lethargy 14
myalgia 9
fatigue 8
sleepiness 5
hypothermia 4
pain 4
nausea 3
diarrhea 3
dyspnea 3
exhaustion 3
ketonuria 2
ataxia 2
collapse 2
anesthesia 2
cough 1
regurgitation 1
overweight 1
Positive and Negative Symptoms 1
angina 1
erythema 1
cyanosis 1
Ill 1
inanition 1
nausea and vomiting 1
Spots 1
stridor 1
hypertonia 1
respiratory distress 1
dysarthria 1
muscle cramps 1
functional recovery 1
hyperoxia 1
Drug
FAD 102
lysine 23
NADH 21
Riboflavin 14
Gel 7
citric acid 6
ROS 5
Liraglutide 2
Flavin 2
Ethanol 2
MAP 2
Asn 2
ALA 2
ABC 2
Glutathione 2
Rosiglitazone 2
Coconut oil 1
Doxycycline 1
Clofibrate 1
PFA 1
CAM 1
SMP 1
Tacrolimus 1
Glycyrrhiza 1
Fructose 1
Retinoic acid 1
Vitamin K 1
EDR 1
pyridoxal phosphate 1
Rifater 1
Bosentan 1
ACT 1
THF 1
IL-1ra 1
Sodium phenylbutyrate 1
Lipidex 1
Estrogens 1
Palmitoyl 1
CTX 1
RFP 1
Rifater 1
AraC 1
Dihydro 1
Bosentan 1
CSF 1
Kenyan 1
Tween 60 1
Bezafibrate 1
DNase I 1
Leaf 1
Serum albumin 1
Glucagon 1
Glutamic acid 1
Enzyme
acyl-CoA dehydrogenase 1425
acyl-CoA dehydrogenase 754
CPT 79
citrate synthase 68
acyl-CoA oxidase 66
3-hydroxyacyl-CoA dehydrogenase 61
3-hydroxyacyl-CoA dehydrogenase 56
ECH 54
KAT 36
acyl-CoA synthetase 34
acyl-CoA synthetase 29
lactate dehydrogenase 27
isovaleryl-CoA dehydrogenase 24
complex I 23
creatine kinase 23
pyruvate dehydrogenase 20
acetyl-CoA carboxylase 20
electron transfer flavoprotein dehydrogenase 18
hexokinase 18
succinate dehydrogenase 17
butyryl-CoA dehydrogenase 17
AMP-activated protein kinase 17
catalase 17
CPT 16
pyruvate dehydrogenase 16
CPT 16
pyruvate dehydrogenase 16
lipoprotein lipase 16
lipase 15
glucose-6-phosphate dehydrogenase 15
ATP synthase 14
cytochrome oxidase 14
ATPase 14
superoxide dismutase 13
glutaryl-CoA dehydrogenase 13
phosphofructokinase 12
protein kinase 10
aldehyde dehydrogenase 9
2,4-dienoyl-CoA reductase 9
biotinidase 9
diaphorase 8
aldehyde dehydrogenase 8
aldehyde dehydrogenase 8
long-chain acyl-coenzyme A dehydrogenase 8
aldehyde dehydrogenase 8
aldehyde dehydrogenase 8
phosphoenolpyruvate carboxykinase 7
AMPK 7
phosphoenolpyruvate carboxykinase 7
ACS 7
malate dehydrogenase 7
isocitrate dehydrogenase 7
phosphoenolpyruvate carboxykinase 7
AMPK 7
glyceraldehyde-3-phosphate dehydrogenase 6
pyruvate kinase 6
isocitrate dehydrogenase 6
PDK1 6
NADH dehydrogenase 6
NAO 6
pyruvate carboxylase 6
aconitase 5
phosphatidylinositol 3-kinase 5
phosphorylase 5
diacylglycerol acyltransferase 5
glutathione reductase 5
diaphorase 5
acetoacetyl-CoA thiolase 5
hormone-sensitive lipase 5
HMG-CoA synthase 5
proteasome 5
glutathione peroxidase 4
glutathione S-transferase 4
isocitrate lyase 4
glyceraldehyde-3-phosphate dehydrogenase 4
malate synthase 4
chloramphenicol acetyltransferase 4
mitogen-activated protein kinase 4
desulfinase 4
3-hydroxy-3-methylglutaryl-CoA lyase 4
carnitine acetyltransferase 4
aspartate aminotransferase 4
p-hydroxybenzoate hydroxylase 4
luciferase 4
p-hydroxybenzoate hydroxylase 4
malonyl-CoA decarboxylase 4
anthranilate hydroxylase 3
ERK 3
glucose oxidase 3
methylmalonyl-CoA mutase 3
hydrogenase 3
hydrogenase 3
thioredoxin reductase 3
ornithine transcarbamylase 3
chaperonin 3
alanine aminotransferase 3
anthranilate hydroxylase 3
focal adhesion kinase 3
PGM 3
branched-chain acyl-CoA dehydrogenase 3
acetyl-CoA synthetase 3
anthranilate hydroxylase 3
alpha-ketoglutarate dehydrogenase 3
alcohol dehydrogenase 3
uricase 3
fumarase 2
alpha-amylase 2
formate dehydrogenase 2
SCS 2
reverse transcriptase 2
succinyl-CoA synthetase 2
RNA polymerase 2
formate dehydrogenase 2
formate dehydrogenase 2
glyceraldehyde-3-phosphate dehydrogenase 2
LPL 2
protein kinase C 2
glyceraldehyde-3-phosphate dehydrogenase 2
SsuE 2
EC 5.3.3.8 2
glycolate oxidase 2
flavin reductase 2
aldolase 2
propionyl-CoA carboxylase 2
lactate oxidase 2
glycerol-3-phosphate dehydrogenase 2
glutathione synthetase 2
glyceraldehyde-3-phosphate dehydrogenase 2
glycerol-3-phosphate dehydrogenase 2
glucose-6-phosphatase 2
acrosin 2
pantothenate kinase 2
3-hydroxybutyryl-CoA dehydrogenase 2
argininosuccinate synthetase 2
succinic dehydrogenase 2
carbonic anhydrase 2
adenylate kinase 2
beta-hydroxybutyrate dehydrogenase 2
CPR 2
dimethylglycine dehydrogenase 2
propionyl-CoA carboxylase 2
sarcosine dehydrogenase 2
BAT 2
methionine adenosyltransferase 2
MAT 2
peroxiredoxin 2
PARP 1
glutamate dehydrogenase 1
branched-chain alpha-keto acid dehydrogenase 1
tryptophan synthase 1
TdT 1
phosphoserine phosphatase 1
melilotate hydroxylase 1
aldose reductase 1
glutamate dehydrogenase 1
thymidine phosphorylase 1
glycerophosphate acyltransferase 1
caspase-1 1
PDH 1
FAD pyrophosphatase 1
more...
Compound
CoA 358
glucose 130
FAD 106
Dec 100
oxygen 81
DNA 75
octanoyl-CoA 70
Clin 69
palmitoyl-CoA 50
hydrogen 49
ATP 47
L-carnitine 46
butyryl-CoA 40
acetyl-CoA 33
phosphate 29
lysine 29
water 27
leucine 26
NAD 25
FMN 23
palmitic acid 22
palmitic acid 22
NADH 21
ubiquinone 20
Carnitine 20
sodium 20
ADP 19
glutamate 19
ADP 18
arginine 18
ADP 17
NAD 17
CPT 16
CPT 16
tyrosine 16
glycerol 15
acetoacetyl-CoA 15
methionine 15
Ile 14
urea 14
Riboflavin 14
glutaryl-CoA 13
adenosylmethionine 13
ethanol 13
isoleucine 13
isoleucine 13
octanoic acid 12
Cardiol 11
Acyl-CoA 11
sulfate 11
His 11
valine 11
acetate 11
alanine 11
octanoic acid 10
GSH 10
cysteine 10
cyanide 10
nitrogen 10
TCA 10
GSH 10
octanoic acid 10
octanoic acid 10
octanoic acid 10
glutamine 10
calcium 10
decanoic acid 9
AMP 9
decanoic acid 9
3-methylcrotonyl-CoA 9
SDS 8
salt 8
ammonia 8
iron 8
H2O2 8
glutamic acid 8
threonine 8
malonyl-CoA 8
NADPH 7
2-ethylhexyl 7
2-ethylhexyl 7
phenazine 7
myristic acid 7
CO2 7
myristic acid 7
potassium 7
TOF 7
Asp 7
2-ethylhexyl 7
serine 7
NADPH 7
tryptophan 6
tryptophan 6
tryptophan 6
creatinine 6
C-3 6
dicarboxylic acid 6
Phe 6
tryptophan 6
hydroquinone 6
3-hydroxybutyryl-CoA 6
CoQ 6
HCI 6
NH2 5
MAD 5
retinoic acid 5
proline 5
coenzyme Q10 5
methanol 5
COS 5
glucose-6-phosphate 5
Gly 5
galactose 5
pentose 4
cAMP 4
pentose 4
HCl 4
ABL 4
pentose 4
pyrimidine 4
butyric acid 4
ACS 4
xylose 4
ubiquinol 4
Triton X-100 4
TNF 4
Insulin 4
adipate 4
butyric acid 4
butyric acid 4
pyrimidine 4
nicotinamide 4
PEG 4
acetonitrile 4
ACS 4
pentose 4
dec-4-enoic acid 3
hexanoic acid 3
lauric acid 3
2-oxoglutarate 3
DEHP 3
ammonium 3
Yellow 3
iodine 3
dUTP 3
silver 3
hydroxide 3
stearic acid 3
DEAE 3
Oleic acid 3
stearic acid 3
alcohol dehydrogenase 3
stearic acid 3
phosphocreatine 3
4-pentenoic acid 3
methanethiol 3
nitric oxide 3
MCP 3
FFA 3
guanidine 3
more...