Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.3.5.1 (succinate dehydrogenase)
8,177 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ATP 646
lactate dehydrogenase 557
NADH 532
Sep 507
ATPase 478
Mol 437
acid phosphatase 366
cytochrome c oxidase 355
malate dehydrogenase 352
SDHB 335
citrate synthase 317
cytochrome 306
alkaline phosphatase 300
ubiquinone 254
endoplasmic reticulum 252
isocitrate dehydrogenase 251
reductase 250
PGL 228
cytochrome c 223
NADH dehydrogenase 220
SDH 216
superoxide dismutase 204
NAD 204
adenosine triphosphatase 201
glucose-6-phosphate dehydrogenase 192
catalase 190
oxidoreductase 184
ADP 181
SDHC 170
flavoprotein 160
glucose-6-phosphatase 146
aconitase 139
insulin 125
cytochrome b 125
SDHA 124
GSH 122
glutamate dehydrogenase 117
complex I) 116
ATP synthase 115
hexokinase 115
alpha-ketoglutarate dehydrogenase 114
esterase 114
membrane-bound 113
creatine kinase 104
phosphofructokinase 103
fumarase 98
TCA 97
NADPH 95
acetylcholinesterase 92
FAD 89
fumarate hydratase 89
polypeptide 87
pyruvate dehydrogenase 83
glutathione peroxidase 83
phosphatase 81
myosin heavy chain 77
microsomal 76
ROS 75
5'-nucleotidase 73
myosin 73
B13 72
pyruvate kinase 72
NADP 71
caspase-3 70
KIT 65
diaphorase 63
peroxidase 62
aspartate aminotransferase 61
membrane protein 57
EPR 55
succinate dehydrogenase subunit B 55
NMR 54
lipopolysaccharide 54
PDGFRA 52
collagen 52
CO2 52
glutathione reductase 51
LDH 49
beta-glucuronidase 48
TNF 48
more...
Disease
tumor 481
cancer 446
paraganglioma 275
pheochromocytoma 193
Huntington's disease 173
ischemia 168
GSH 122
diabetes 106
Hippel 105
tumorigenesis 94
Parkinson's disease 77
stromal tumors 72
carcinoma 70
Alzheimer's disease 68
myopathy 63
renal cell carcinoma 63
gastrointestinal stromal tumor 63
cold 62
stroke 60
depression 57
metastases 56
neuroblastoma 52
mitochondrial disease 51
multiple endocrine neoplasia 47
lactic acidosis 47
hypertension 45
mitochondrial myopathy 45
carcinogenesis 45
encephalopathy 43
hepatocellular carcinoma 43
obesity 42
cardiomyopathy 39
neurofibromatosis type 1 38
heart failure 37
myocardial infarction 34
SDS 34
Leigh syndrome 34
gastric cancer 31
cerebral ischemia 31
type 2 diabetes 30
sepsis 29
breast cancer 29
sepsis 28
tumor growth 28
Friedreich's ataxia 28
epilepsy 26
amyotrophic lateral sclerosis 25
fits 23
epididymis 23
myocardial ischemia 23
DDP 21
melanoma 21
iron deficiency 21
lung cancer 20
hyperglycemia 20
neurofibromatosis 18
tuberculosis 18
sarcoma 18
cognitive impairment 17
liver disease 17
anemia 17
adenocarcinoma 17
malaria 17
tumor progression 16
hyperthyroidism 16
HIV 16
Brown 16
PCC 16
leukemia 15
renal cancer 15
malnutrition 15
worms 15
dilated cardiomyopathy 14
MELAS 14
atherosclerosis 14
dementia 14
MELAS 14
fatty liver 14
NAME 13
Mycobacterium 13
more...
Symptom
fatigue 102
weakness 53
collapse 43
starvation 32
seizures 31
ataxia 25
ophthalmoplegia 21
anesthesia 19
hyperoxia 18
hypotonia 18
exhaustion 15
headache 14
dystonia 12
hypothermia 11
acidity 10
myalgia 9
pain 9
diarrhea 8
chorea 6
nausea 5
functional recovery 5
vomiting 5
dyspnea 5
cachexia 5
Decreased activity 4
twitching 4
hepatomegaly 4
angina 4
paresis 3
tinnitus 3
erythema 3
incoordination 3
dysarthria 3
neurological disability 3
tremor 3
cyanosis 2
lethargy 2
cerebellar ataxia 2
stigma 2
discomfort 2
discomfort 2
insomnia 2
myoclonus 2
ketonuria 2
respiratory distress 2
astasia 2
flushing 2
flank pain 2
chronic constipation 2
Anoxia 1
abnormal gait 1
dry eye 1
hoarseness 1
Hyperekplexia 1
acute stress 1
vertigo 1
syncope 1
masculinization 1
overweight 1
polyuria 1
Respiration stimulated 1
splenomegaly 1
tonic seizure 1
exertional angina 1
Ill 1
Deafferentation 1
chest pain 1
leg edema 1
abdominal discomfort 1
exertional dyspnea 1
hangover 1
anorexia 1
chest tightness 1
thinning 1
back pain 1
Exercise intolerance 1
hypercapnia 1
paraparesis 1
agitation 1
eds 1
more...
Drug
NADH 545
citric acid 102
FAD 89
ROS 75
ascorbate 67
vitamin E 38
lysine 36
Ethanol 13
Dermatol 12
Cardiovasc 11
Nephron 11
Adriamycin 11
Gel 10
NBT 10
CTX 8
Parkin 7
Riboflavin 7
Parkin 7
Vitamin E 7
DNase I 6
Leaf 6
Indomethacin 5
CSF 5
TiO2 5
MAP 5
Propofol 5
Glutathione 5
ADM 5
ALA 5
Lovastatin 4
CaCl2 4
CaCl2 4
Flavin 4
ABC 4
L-tyrosine 4
caffeine 4
DMI 4
AZT 4
lactose 4
AZT 4
ETS 4
CaCl2 4
PTH 4
PCP 4
Ouabain 3
AraC 3
THF 3
Biopolymers 3
Succinobucol 3
Fluorescein 3
ADR 3
Mutagen 3
Asn 3
Glucagon 3
NH3 3
CTC 3
Photofrin II 3
Pravastatin 3
IL-2 3
Gleevec 3
FeCl3 3
niacin 3
CAM 3
CTC 3
Vitamin K 3
p75 2
Heme 2
Diurnal 2
Ringer's solution 2
Liraglutide 2
Vinpocetine 2
Nephron 2
Angiotensin II 2
nitroglycerin 2
MRC 2
PCB 2
Acacia 2
Sorafenib 2
Phenytoin 2
CTT 2
more...
Enzyme
succinate dehydrogenase 8177
succinic dehydrogenase 1240
complex I 1057
ATPase 742
cytochrome oxidase 640
lactate dehydrogenase 625
diaphorase 434
malate dehydrogenase 392
acid phosphatase 366
citrate synthase 328
alkaline phosphatase 301
isocitrate dehydrogenase 272
isocitrate dehydrogenase 258
superoxide dismutase 237
glucose-6-phosphate dehydrogenase 225
NADH dehydrogenase 223
glycerol-3-phosphate dehydrogenase 198
glycerol-3-phosphate dehydrogenase 197
catalase 194
fumarase 181
CPR 178
fumarate reductase 168
alpha-ketoglutarate dehydrogenase 157
aconitase 148
glucose-6-phosphatase 146
phosphorylase 144
ERK 141
ATP synthase 135
glutamate dehydrogenase 126
glutamate dehydrogenase 126
glutamate dehydrogenase 123
creatine kinase 123
acetylcholinesterase 117
hexokinase 116
pyruvate dehydrogenase 116
phosphofructokinase 107
peroxidase 99
monoamine oxidase 94
NADPH-diaphorase 92
NQO1 86
pyruvate dehydrogenase 84
diaphorase 83
pyruvate dehydrogenase 83
glutathione peroxidase 83
5'-nucleotidase 76
pyruvate kinase 72
aspartate aminotransferase 68
alanine aminotransferase 64
myosin ATPase 61
protein kinase 53
glutathione reductase 51
glyceraldehyde-3-phosphate dehydrogenase 51
caspase-3 50
beta-hydroxybutyrate dehydrogenase 50
mitogen-activated protein kinase 49
aldolase 47
beta-glucuronidase 46
glyceraldehyde-3-phosphate dehydrogenase 43
glyceraldehyde-3-phosphate dehydrogenase 41
cholinesterase 41
glyceraldehyde-3-phosphate dehydrogenase 40
glyceraldehyde-3-phosphate dehydrogenase 40
phosphoenolpyruvate carboxykinase 38
SCS 37
succinyl-CoA synthetase 37
phosphoenolpyruvate carboxykinase 37
phosphoenolpyruvate carboxykinase 35
gamma-glutamyl transpeptidase 35
AMP-activated protein kinase 33
NADPH oxidase 33
xanthine oxidase 32
isocitrate lyase 30
alcohol dehydrogenase 29
3-hydroxyacyl-CoA dehydrogenase 27
6-phosphogluconate dehydrogenase 26
3-hydroxyacyl-CoA dehydrogenase 26
6-phosphogluconate dehydrogenase 26
glutathione S-transferase 26
PAL 25
beta-galactosidase 25
more...
Compound
oxygen 1172
ATP 646
DNA 616
Dec 564
NADH 545
glucose 519
iron 367
calcium 271
succinic acid 268
sodium 264
glutamate 261
phosphate 258
ubiquinone 257
NAD 250
water 234
NAD 204
ADP 198
ADP 182
ADP 182
2-oxoglutarate 151
hydrogen 146
Clin 137
GSH 128
GSH 128
acetate 127
nicotinamide 115
TCA 103
NADPH 96
NADPH 95
NADP 94
FAD 91
cysteine 89
ubiquinol 87
potassium 87
cyanide 85
nitrogen 84
MTT 83
ethanol 82
nitric oxide 82
H2O2 81
sulfate 80
glycerol 80
CO2 79
His 75
CoA 74
salt 73
copper 73
dicarboxylic acid 71
alanine 68
arginine 67
tyrosine 62
NPA 59
leucine 56
BNP 55
bromide 54
pentose 52
glutamine 52
pentose 52
pentose 52
pentose 52
ammonium 49
TNF 48
Lactate 48
zinc 47
manganese 47
isocitrate 46
galactose 45
Triton X-100 45
methionine 44
Mg2+ 44
lysine 43
phenazine 43
SDS 43
nitrate 42
Malonate 42
Cytochrome c 41
GABA 41
GABA 41
urea 40
succinic acid 39
more...