Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.3.5.1 (
succinate dehydrogenase
)
8,177
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ATP
646
lactate dehydrogenase
557
NADH
532
Sep
507
ATPase
478
Mol
437
acid phosphatase
366
cytochrome c oxidase
355
malate dehydrogenase
352
SDHB
335
citrate synthase
317
cytochrome
306
alkaline phosphatase
300
ubiquinone
254
endoplasmic reticulum
252
isocitrate dehydrogenase
251
reductase
250
PGL
228
cytochrome c
223
NADH dehydrogenase
220
SDH
216
superoxide dismutase
204
NAD
204
adenosine triphosphatase
201
glucose-6-phosphate dehydrogenase
192
catalase
190
oxidoreductase
184
ADP
181
SDHC
170
flavoprotein
160
glucose-6-phosphatase
146
aconitase
139
insulin
125
cytochrome b
125
SDHA
124
GSH
122
glutamate dehydrogenase
117
complex I)
116
ATP synthase
115
hexokinase
115
alpha-ketoglutarate dehydrogenase
114
esterase
114
membrane-bound
113
creatine kinase
104
phosphofructokinase
103
fumarase
98
TCA
97
NADPH
95
acetylcholinesterase
92
FAD
89
fumarate hydratase
89
polypeptide
87
pyruvate dehydrogenase
83
glutathione peroxidase
83
phosphatase
81
myosin heavy chain
77
microsomal
76
ROS
75
5'-nucleotidase
73
myosin
73
B13
72
pyruvate kinase
72
NADP
71
caspase-3
70
KIT
65
diaphorase
63
peroxidase
62
aspartate aminotransferase
61
membrane protein
57
EPR
55
succinate dehydrogenase subunit B
55
NMR
54
lipopolysaccharide
54
PDGFRA
52
collagen
52
CO2
52
glutathione reductase
51
LDH
49
beta-glucuronidase
48
TNF
48
more...
Disease
tumor
481
cancer
446
paraganglioma
275
pheochromocytoma
193
Huntington's disease
173
ischemia
168
GSH
122
diabetes
106
Hippel
105
tumorigenesis
94
Parkinson's disease
77
stromal tumors
72
carcinoma
70
Alzheimer's disease
68
myopathy
63
renal cell carcinoma
63
gastrointestinal stromal tumor
63
cold
62
stroke
60
depression
57
metastases
56
neuroblastoma
52
mitochondrial disease
51
multiple endocrine neoplasia
47
lactic acidosis
47
hypertension
45
mitochondrial myopathy
45
carcinogenesis
45
encephalopathy
43
hepatocellular carcinoma
43
obesity
42
cardiomyopathy
39
neurofibromatosis type 1
38
heart failure
37
myocardial infarction
34
SDS
34
Leigh syndrome
34
gastric cancer
31
cerebral ischemia
31
type 2 diabetes
30
sepsis
29
breast cancer
29
sepsis
28
tumor growth
28
Friedreich's ataxia
28
epilepsy
26
amyotrophic lateral sclerosis
25
fits
23
epididymis
23
myocardial ischemia
23
DDP
21
melanoma
21
iron deficiency
21
lung cancer
20
hyperglycemia
20
neurofibromatosis
18
tuberculosis
18
sarcoma
18
cognitive impairment
17
liver disease
17
anemia
17
adenocarcinoma
17
malaria
17
tumor progression
16
hyperthyroidism
16
HIV
16
Brown
16
PCC
16
leukemia
15
renal cancer
15
malnutrition
15
worms
15
dilated cardiomyopathy
14
MELAS
14
atherosclerosis
14
dementia
14
MELAS
14
fatty liver
14
NAME
13
Mycobacterium
13
more...
Symptom
fatigue
102
weakness
53
collapse
43
starvation
32
seizures
31
ataxia
25
ophthalmoplegia
21
anesthesia
19
hyperoxia
18
hypotonia
18
exhaustion
15
headache
14
dystonia
12
hypothermia
11
acidity
10
myalgia
9
pain
9
diarrhea
8
chorea
6
nausea
5
functional recovery
5
vomiting
5
dyspnea
5
cachexia
5
Decreased activity
4
twitching
4
hepatomegaly
4
angina
4
paresis
3
tinnitus
3
erythema
3
incoordination
3
dysarthria
3
neurological disability
3
tremor
3
cyanosis
2
lethargy
2
cerebellar ataxia
2
stigma
2
discomfort
2
discomfort
2
insomnia
2
myoclonus
2
ketonuria
2
respiratory distress
2
astasia
2
flushing
2
flank pain
2
chronic constipation
2
Anoxia
1
abnormal gait
1
dry eye
1
hoarseness
1
Hyperekplexia
1
acute stress
1
vertigo
1
syncope
1
masculinization
1
overweight
1
polyuria
1
Respiration stimulated
1
splenomegaly
1
tonic seizure
1
exertional angina
1
Ill
1
Deafferentation
1
chest pain
1
leg edema
1
abdominal discomfort
1
exertional dyspnea
1
hangover
1
anorexia
1
chest tightness
1
thinning
1
back pain
1
Exercise intolerance
1
hypercapnia
1
paraparesis
1
agitation
1
eds
1
more...
Drug
NADH
545
citric acid
102
FAD
89
ROS
75
ascorbate
67
vitamin E
38
lysine
36
Ethanol
13
Dermatol
12
Cardiovasc
11
Nephron
11
Adriamycin
11
Gel
10
NBT
10
CTX
8
Parkin
7
Riboflavin
7
Parkin
7
Vitamin E
7
DNase I
6
Leaf
6
Indomethacin
5
CSF
5
TiO2
5
MAP
5
Propofol
5
Glutathione
5
ADM
5
ALA
5
Lovastatin
4
CaCl2
4
CaCl2
4
Flavin
4
ABC
4
L-tyrosine
4
caffeine
4
DMI
4
AZT
4
lactose
4
AZT
4
ETS
4
CaCl2
4
PTH
4
PCP
4
Ouabain
3
AraC
3
THF
3
Biopolymers
3
Succinobucol
3
Fluorescein
3
ADR
3
Mutagen
3
Asn
3
Glucagon
3
NH3
3
CTC
3
Photofrin II
3
Pravastatin
3
IL-2
3
Gleevec
3
FeCl3
3
niacin
3
CAM
3
CTC
3
Vitamin K
3
p75
2
Heme
2
Diurnal
2
Ringer's solution
2
Liraglutide
2
Vinpocetine
2
Nephron
2
Angiotensin II
2
nitroglycerin
2
MRC
2
PCB
2
Acacia
2
Sorafenib
2
Phenytoin
2
CTT
2
more...
Enzyme
succinate dehydrogenase
8177
succinic dehydrogenase
1240
complex I
1057
ATPase
742
cytochrome oxidase
640
lactate dehydrogenase
625
diaphorase
434
malate dehydrogenase
392
acid phosphatase
366
citrate synthase
328
alkaline phosphatase
301
isocitrate dehydrogenase
272
isocitrate dehydrogenase
258
superoxide dismutase
237
glucose-6-phosphate dehydrogenase
225
NADH dehydrogenase
223
glycerol-3-phosphate dehydrogenase
198
glycerol-3-phosphate dehydrogenase
197
catalase
194
fumarase
181
CPR
178
fumarate reductase
168
alpha-ketoglutarate dehydrogenase
157
aconitase
148
glucose-6-phosphatase
146
phosphorylase
144
ERK
141
ATP synthase
135
glutamate dehydrogenase
126
glutamate dehydrogenase
126
glutamate dehydrogenase
123
creatine kinase
123
acetylcholinesterase
117
hexokinase
116
pyruvate dehydrogenase
116
phosphofructokinase
107
peroxidase
99
monoamine oxidase
94
NADPH-diaphorase
92
NQO1
86
pyruvate dehydrogenase
84
diaphorase
83
pyruvate dehydrogenase
83
glutathione peroxidase
83
5'-nucleotidase
76
pyruvate kinase
72
aspartate aminotransferase
68
alanine aminotransferase
64
myosin ATPase
61
protein kinase
53
glutathione reductase
51
glyceraldehyde-3-phosphate dehydrogenase
51
caspase-3
50
beta-hydroxybutyrate dehydrogenase
50
mitogen-activated protein kinase
49
aldolase
47
beta-glucuronidase
46
glyceraldehyde-3-phosphate dehydrogenase
43
glyceraldehyde-3-phosphate dehydrogenase
41
cholinesterase
41
glyceraldehyde-3-phosphate dehydrogenase
40
glyceraldehyde-3-phosphate dehydrogenase
40
phosphoenolpyruvate carboxykinase
38
SCS
37
succinyl-CoA synthetase
37
phosphoenolpyruvate carboxykinase
37
phosphoenolpyruvate carboxykinase
35
gamma-glutamyl transpeptidase
35
AMP-activated protein kinase
33
NADPH oxidase
33
xanthine oxidase
32
isocitrate lyase
30
alcohol dehydrogenase
29
3-hydroxyacyl-CoA dehydrogenase
27
6-phosphogluconate dehydrogenase
26
3-hydroxyacyl-CoA dehydrogenase
26
6-phosphogluconate dehydrogenase
26
glutathione S-transferase
26
PAL
25
beta-galactosidase
25
more...
Compound
oxygen
1172
ATP
646
DNA
616
Dec
564
NADH
545
glucose
519
iron
367
calcium
271
succinic acid
268
sodium
264
glutamate
261
phosphate
258
ubiquinone
257
NAD
250
water
234
NAD
204
ADP
198
ADP
182
ADP
182
2-oxoglutarate
151
hydrogen
146
Clin
137
GSH
128
GSH
128
acetate
127
nicotinamide
115
TCA
103
NADPH
96
NADPH
95
NADP
94
FAD
91
cysteine
89
ubiquinol
87
potassium
87
cyanide
85
nitrogen
84
MTT
83
ethanol
82
nitric oxide
82
H2O2
81
sulfate
80
glycerol
80
CO2
79
His
75
CoA
74
salt
73
copper
73
dicarboxylic acid
71
alanine
68
arginine
67
tyrosine
62
NPA
59
leucine
56
BNP
55
bromide
54
pentose
52
glutamine
52
pentose
52
pentose
52
pentose
52
ammonium
49
TNF
48
Lactate
48
zinc
47
manganese
47
isocitrate
46
galactose
45
Triton X-100
45
methionine
44
Mg2+
44
lysine
43
phenazine
43
SDS
43
nitrate
42
Malonate
42
Cytochrome c
41
GABA
41
GABA
41
urea
40
succinic acid
39
more...