Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.3.5.1 (
succinate dehydrogenase
)
8,177
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ATP
646
lactate dehydrogenase
557
NADH
532
Sep
507
ATPase
478
Mol
437
acid phosphatase
366
cytochrome c oxidase
355
malate dehydrogenase
352
SDHB
335
citrate synthase
317
cytochrome
306
alkaline phosphatase
300
ubiquinone
254
endoplasmic reticulum
252
isocitrate dehydrogenase
251
reductase
250
PGL
228
cytochrome c
223
NADH dehydrogenase
220
SDH
216
NAD
204
superoxide dismutase
204
adenosine triphosphatase
201
glucose-6-phosphate dehydrogenase
192
catalase
190
oxidoreductase
184
ADP
181
SDHC
170
flavoprotein
160
glucose-6-phosphatase
146
aconitase
139
cytochrome b
125
insulin
125
SDHA
124
GSH
122
glutamate dehydrogenase
117
complex I)
116
ATP synthase
115
hexokinase
115
more...
Disease
tumor
481
cancer
446
paraganglioma
275
pheochromocytoma
193
Huntington's disease
173
ischemia
168
GSH
122
diabetes
106
Hippel
105
tumorigenesis
94
Parkinson's disease
77
stromal tumors
72
carcinoma
70
Alzheimer's disease
68
myopathy
63
gastrointestinal stromal tumor
63
renal cell carcinoma
63
cold
62
stroke
60
depression
57
metastases
56
neuroblastoma
52
mitochondrial disease
51
lactic acidosis
47
multiple endocrine neoplasia
47
mitochondrial myopathy
45
carcinogenesis
45
hypertension
45
encephalopathy
43
hepatocellular carcinoma
43
obesity
42
cardiomyopathy
39
neurofibromatosis type 1
38
heart failure
37
myocardial infarction
34
SDS
34
Leigh syndrome
34
cerebral ischemia
31
gastric cancer
31
type 2 diabetes
30
more...
Symptom
fatigue
102
weakness
53
collapse
43
starvation
32
seizures
31
ataxia
25
ophthalmoplegia
21
anesthesia
19
hyperoxia
18
hypotonia
18
exhaustion
15
headache
14
dystonia
12
hypothermia
11
acidity
10
myalgia
9
pain
9
diarrhea
8
chorea
6
cachexia
5
vomiting
5
nausea
5
functional recovery
5
dyspnea
5
Decreased activity
4
twitching
4
hepatomegaly
4
angina
4
erythema
3
neurological disability
3
incoordination
3
tinnitus
3
paresis
3
dysarthria
3
tremor
3
lethargy
2
cyanosis
2
ketonuria
2
chronic constipation
2
astasia
2
more...
Drug
NADH
545
citric acid
102
FAD
89
ROS
75
ascorbate
67
vitamin E
38
lysine
36
Ethanol
13
Dermatol
12
Nephron
11
Adriamycin
11
Cardiovasc
11
Gel
10
NBT
10
CTX
8
Vitamin E
7
Riboflavin
7
Parkin
7
Parkin
7
DNase I
6
Leaf
6
Propofol
5
ALA
5
CSF
5
Indomethacin
5
ADM
5
Glutathione
5
TiO2
5
MAP
5
Lovastatin
4
AZT
4
AZT
4
PTH
4
CaCl2
4
CaCl2
4
ABC
4
caffeine
4
lactose
4
DMI
4
CaCl2
4
more...
Enzyme
succinate dehydrogenase
8177
succinic dehydrogenase
1240
complex I
1057
ATPase
742
cytochrome oxidase
640
lactate dehydrogenase
625
diaphorase
434
malate dehydrogenase
392
acid phosphatase
366
citrate synthase
328
alkaline phosphatase
301
isocitrate dehydrogenase
272
isocitrate dehydrogenase
258
superoxide dismutase
237
glucose-6-phosphate dehydrogenase
225
NADH dehydrogenase
223
glycerol-3-phosphate dehydrogenase
198
glycerol-3-phosphate dehydrogenase
197
catalase
194
fumarase
181
CPR
178
fumarate reductase
168
alpha-ketoglutarate dehydrogenase
157
aconitase
148
glucose-6-phosphatase
146
phosphorylase
144
ERK
141
ATP synthase
135
glutamate dehydrogenase
126
glutamate dehydrogenase
126
creatine kinase
123
glutamate dehydrogenase
123
acetylcholinesterase
117
hexokinase
116
pyruvate dehydrogenase
116
phosphofructokinase
107
peroxidase
99
monoamine oxidase
94
NADPH-diaphorase
92
NQO1
86
more...
Compound
oxygen
1172
ATP
646
DNA
616
Dec
564
NADH
545
glucose
519
iron
367
calcium
271
succinic acid
268
sodium
264
glutamate
261
phosphate
258
ubiquinone
257
NAD
250
water
234
NAD
204
ADP
198
ADP
182
ADP
182
2-oxoglutarate
151
hydrogen
146
Clin
137
GSH
128
GSH
128
acetate
127
nicotinamide
115
TCA
103
NADPH
96
NADPH
95
NADP
94
FAD
91
cysteine
89
potassium
87
ubiquinol
87
cyanide
85
nitrogen
84
MTT
83
nitric oxide
82
ethanol
82
H2O2
81
more...