Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.3.5.1 (succinate dehydrogenase)
 8,177 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ATP 646
lactate dehydrogenase 557
NADH 532
Sep 507
ATPase 478
Mol 437
acid phosphatase 366
cytochrome c oxidase 355
malate dehydrogenase 352
SDHB 335
citrate synthase 317
cytochrome 306
alkaline phosphatase 300
ubiquinone 254
endoplasmic reticulum 252
isocitrate dehydrogenase 251
reductase 250
PGL 228
cytochrome c 223
NADH dehydrogenase 220
SDH 216
NAD 204
superoxide dismutase 204
adenosine triphosphatase 201
glucose-6-phosphate dehydrogenase 192
catalase 190
oxidoreductase 184
ADP 181
SDHC 170
flavoprotein 160
glucose-6-phosphatase 146
aconitase 139
insulin 125
cytochrome b 125
SDHA 124
GSH 122
glutamate dehydrogenase 117
complex I) 116
ATP synthase 115
hexokinase 115
alpha-ketoglutarate dehydrogenase 114
esterase 114
membrane-bound 113
creatine kinase 104
phosphofructokinase 103
fumarase 98
TCA 97
NADPH 95
acetylcholinesterase 92
fumarate hydratase 89
FAD 89
polypeptide 87
pyruvate dehydrogenase 83
glutathione peroxidase 83
phosphatase 81
myosin heavy chain 77
microsomal 76
ROS 75
myosin 73
5'-nucleotidase 73
B13 72
pyruvate kinase 72
NADP 71
caspase-3 70
KIT 65
diaphorase 63
peroxidase 62
aspartate aminotransferase 61
membrane protein 57
succinate dehydrogenase subunit B 55
EPR 55
NMR 54
lipopolysaccharide 54
CO2 52
PDGFRA 52
collagen 52
glutathione reductase 51
LDH 49
TNF 48
beta-glucuronidase 48
Gen 48
glycerol-3-phosphate dehydrogenase 44
Chlamydomonas 44
PGC 44
VHL 43
Cytochrome c 41
GABA 41
NAD+ 40
Bcl-2 40
SOD 40
glyceraldehyde-3-phosphate dehydrogenase 40
RET 38
nitric oxide synthase 38
cytokine 35
glycogen phosphorylase 35
alanine aminotransferase 34
NF1 34
cardiac muscle 34
SDS 34
Pseudomonas 34
quinone oxidoreductase 33
huntingtin 33
neurofibromatosis type 1 32
2-oxoglutarate dehydrogenase 32
COX 32
histone 31
NMDA receptor 31
tumor necrosis factor 31
frataxin 30
antioxidant enzyme 30
adenosinetriphosphatase 30
xanthine oxidase 30
p53 30
Citrate synthase 29
AMP 29
Pol 29
hemoglobin 29
phosphoenolpyruvate carboxykinase 28
ferredoxin 28
cytochrome aa3 28
myoglobin 28
tyrosine kinase 28
SDH2 27
alcohol dehydrogenase 26
proximal tubule 26
BRAF 26
6-phosphogluconate dehydrogenase 25
NADH-ubiquinone oxidoreductase 25
tRNA 25
pyruvate dehydrogenase complex 25
pyruvate carboxylase 25
dimeric 24
spermatozoa 24
phosphorylating 24
CA1 24
peroxisome proliferator-activated receptor 24
erythroid 24
GTP 24
ubiquitin 24
myeloperoxidase 23
neurofibromatosis 23
caspase-8 23
cytochrome bc1 23
IL-6 23
gamma-glutamyl transpeptidase 23
cage 23
AED 22
peroxisome proliferator-activated receptor gamma 22
PDH 22
serum albumin 22
GTPase 21
brush border 21
AMP-activated protein kinase 21
gut 21
Alkaline phosphatase 20
manganese superoxide dismutase 20
OXPHOS 20
fused 20
albumin 20
isocitric dehydrogenase 20
more...
Disease
tumor 481
cancer 446
paraganglioma 275
pheochromocytoma 193
Huntington's disease 173
ischemia 168
GSH 122
diabetes 106
Hippel 105
tumorigenesis 94
Parkinson's disease 77
stromal tumors 72
carcinoma 70
Alzheimer's disease 68
gastrointestinal stromal tumor 63
myopathy 63
renal cell carcinoma 63
cold 62
stroke 60
depression 57
metastases 56
neuroblastoma 52
mitochondrial disease 51
multiple endocrine neoplasia 47
lactic acidosis 47
mitochondrial myopathy 45
carcinogenesis 45
hypertension 45
encephalopathy 43
hepatocellular carcinoma 43
obesity 42
cardiomyopathy 39
neurofibromatosis type 1 38
heart failure 37
Leigh syndrome 34
myocardial infarction 34
SDS 34
cerebral ischemia 31
gastric cancer 31
type 2 diabetes 30
breast cancer 29
sepsis 29
sepsis 28
tumor growth 28
Friedreich's ataxia 28
epilepsy 26
amyotrophic lateral sclerosis 25
epididymis 23
myocardial ischemia 23
fits 23
iron deficiency 21
melanoma 21
DDP 21
lung cancer 20
hyperglycemia 20
tuberculosis 18
neurofibromatosis 18
sarcoma 18
adenocarcinoma 17
liver disease 17
cognitive impairment 17
malaria 17
anemia 17
HIV 16
PCC 16
hyperthyroidism 16
tumor progression 16
Brown 16
renal cancer 15
worms 15
leukemia 15
malnutrition 15
dementia 14
MELAS 14
fatty liver 14
MELAS 14
atherosclerosis 14
dilated cardiomyopathy 14
hepatitis 13
mitochondrial encephalomyopathy 13
suicide 13
adenoma 13
NAME 13
Mycobacterium 13
colorectal cancer 13
glioma 13
PMS 12
metabolic syndrome 12
premenstrual syndrome 12
methylmalonic acidemia 12
MEN 2 12
congestive heart failure 12
muscular atrophy 12
thyroid cancer 11
genetic disorder 11
colon cancer 11
SEM 11
lymphoma 11
cardiovascular disease 11
parkinsonism 10
neuropathy 10
neoplastic transformation 10
Graves' disease 10
chronic obstructive pulmonary disease 10
dysplasia 10
renal disease 10
hypertrophic cardiomyopathy 10
hypothyroidism 10
MCF 10
neurological disease 9
Giant 9
cirrhosis 9
Kearns-Sayre syndrome 9
glioblastoma 9
immunodeficiency 9
leukoencephalopathy 9
acute myeloid leukemia 9
myoclonus epilepsy 9
hypoglycemia 9
acute renal failure 9
virus infection 9
respiratory failure 9
mental retardation 8
Evans 8
deafness 8
metabolic disorder 8
tuberous sclerosis 8
bipolar disorder 8
mole 8
developmental delay 8
optic atrophy 8
goiter 8
mole 8
Leber's hereditary optic neuropathy 8
tetanus 8
chondroma 8
Blocking 8
emotional stress 7
mania 7
aggressiveness 7
glucose intolerance 7
medullary thyroid carcinoma 7
Syndrome 7
squamous cell carcinoma 7
dehydration 7
B-cell lymphoma 7
primary pulmonary hypertension 7
Diaphragm 7
Chagas 7
pituitary adenoma 7
cystic fibrosis 7
plague 7
pulmonary hypertension 7
emphysema 7
hyperlipidemia 7
Cowden syndrome 7
primary tumor 7
encephalomyelitis 7
myocarditis 7
non-small cell lung cancer 6
more...
Symptom
fatigue 102
weakness 53
collapse 43
starvation 32
seizures 31
ataxia 25
ophthalmoplegia 21
anesthesia 19
hyperoxia 18
hypotonia 18
exhaustion 15
headache 14
dystonia 12
hypothermia 11
acidity 10
pain 9
myalgia 9
diarrhea 8
chorea 6
nausea 5
vomiting 5
dyspnea 5
cachexia 5
functional recovery 5
Decreased activity 4
twitching 4
hepatomegaly 4
angina 4
incoordination 3
paresis 3
tinnitus 3
erythema 3
dysarthria 3
neurological disability 3
tremor 3
cyanosis 2
lethargy 2
flushing 2
ketonuria 2
stigma 2
discomfort 2
discomfort 2
insomnia 2
myoclonus 2
respiratory distress 2
cerebellar ataxia 2
astasia 2
flank pain 2
chronic constipation 2
Anoxia 1
abnormal gait 1
dry eye 1
hoarseness 1
Hyperekplexia 1
acute stress 1
vertigo 1
syncope 1
masculinization 1
overweight 1
polyuria 1
Respiration stimulated 1
Fatigability 1
tonic seizure 1
fasciculation 1
thinning 1
splenomegaly 1
bradykinesia 1
Deafferentation 1
chest pain 1
leg edema 1
abdominal discomfort 1
exertional dyspnea 1
hangover 1
anorexia 1
chest tightness 1
Ill 1
exertional angina 1
back pain 1
Exercise intolerance 1
hypercapnia 1
paraparesis 1
agitation 1
eds 1
numbness 1
bitter taste 1
anosmia 1
Extrapyramidal symptoms 1
male subfertility 1
Drug
NADH 545
citric acid 102
FAD 89
ROS 75
ascorbate 67
vitamin E 38
lysine 36
Ethanol 13
Dermatol 12
Cardiovasc 11
Adriamycin 11
Nephron 11
Gel 10
NBT 10
CTX 8
Riboflavin 7
Parkin 7
Parkin 7
Vitamin E 7
DNase I 6
Leaf 6
CSF 5
Glutathione 5
MAP 5
ALA 5
Propofol 5
TiO2 5
ADM 5
Indomethacin 5
Lovastatin 4
L-tyrosine 4
CaCl2 4
ETS 4
PTH 4
CaCl2 4
AZT 4
Flavin 4
DMI 4
CaCl2 4
ABC 4
caffeine 4
lactose 4
AZT 4
PCP 4
ADR 3
NH3 3
IL-2 3
Ouabain 3
Photofrin II 3
Biopolymers 3
Succinobucol 3
FeCl3 3
CTC 3
niacin 3
THF 3
Gleevec 3
Asn 3
CAM 3
AraC 3
Glucagon 3
Pravastatin 3
CTC 3
Fluorescein 3
Mutagen 3
Vitamin K 3
Diurnal 2
Estrogens 2
Nephron 2
Alanine 2
Ringer's solution 2
p75 2
Nitric Oxide 2
Methylene blue 2
Phenytoin 2
CTT 2
ampicillin 2
Heme 2
Vinpocetine 2
Liraglutide 2
Simvastatin 2
Adenosine triphosphate 2
Acacia 2
Angiotensin II 2
nitroglycerin 2
MRC 2
RFP 2
Sodium valproate 2
APM 2
9-THC 2
TTC 2
THA 2
Carotenoid 2
PCB 2
Ammonium chloride 2
Photofrin 2
Fraction 2
pyridoxal phosphate 2
ICI 2
Sorafenib 2
Enrofloxacin 1
Bayer 1
Fructose 1
TMX 1
Glycyrrhiza 1
ETA 1
Fluorescein 1
IFN-gamma 1
Flunitrazepam 1
Gemfibrozil 1
DFP 1
Florisil 1
Forskolin 1
Lactose 1
Dymelor 1
Triclosan 1
Avilamycin 1
Growth hormone 1
Mercaptopurine 1
Zinc sulfate 1
Chlorate 1
Ramipril 1
Helium 1
1,8-Cineole 1
Fluconazole 1
Isoniazid 1
Zinc sulfate 1
Histamine 1
Arsenic trioxide 1
Abamectin 1
TMS 1
Mesalazine 1
Guanidine 1
Iloprost 1
Fenbendazole 1
Imatinib 1
CET 1
3,4-Dihydroxyphenylalanine 1
Diastase 1
Tocopherol 1
Idebenone 1
Imferon 1
Epigallocatechin 1
Furan 1
Mineral oil 1
Hypaque 1
Metrizamide 1
DPA 1
Pefloxacin 1
beta-Galactosidase 1
Naftidrofuryl 1
Asthma 1
CIA 1
Betaloc 1
CPM 1
Cimetidine 1
Triad 1
Portal 1
Piracetam 1
Bosentan 1
Monensin 1
more...
Enzyme
succinate dehydrogenase 8177
succinic dehydrogenase 1240
complex I 1057
ATPase 742
cytochrome oxidase 640
lactate dehydrogenase 625
diaphorase 434
malate dehydrogenase 392
acid phosphatase 366
citrate synthase 328
alkaline phosphatase 301
isocitrate dehydrogenase 272
isocitrate dehydrogenase 258
superoxide dismutase 237
glucose-6-phosphate dehydrogenase 225
NADH dehydrogenase 223
glycerol-3-phosphate dehydrogenase 198
glycerol-3-phosphate dehydrogenase 197
catalase 194
fumarase 181
CPR 178
fumarate reductase 168
alpha-ketoglutarate dehydrogenase 157
aconitase 148
glucose-6-phosphatase 146
phosphorylase 144
ERK 141
ATP synthase 135
glutamate dehydrogenase 126
glutamate dehydrogenase 126
creatine kinase 123
glutamate dehydrogenase 123
acetylcholinesterase 117
hexokinase 116
pyruvate dehydrogenase 116
phosphofructokinase 107
peroxidase 99
monoamine oxidase 94
NADPH-diaphorase 92
NQO1 86
pyruvate dehydrogenase 84
pyruvate dehydrogenase 83
glutathione peroxidase 83
diaphorase 83
5'-nucleotidase 76
pyruvate kinase 72
aspartate aminotransferase 68
alanine aminotransferase 64
myosin ATPase 61
protein kinase 53
glyceraldehyde-3-phosphate dehydrogenase 51
glutathione reductase 51
caspase-3 50
beta-hydroxybutyrate dehydrogenase 50
mitogen-activated protein kinase 49
aldolase 47
beta-glucuronidase 46
glyceraldehyde-3-phosphate dehydrogenase 43
cholinesterase 41
glyceraldehyde-3-phosphate dehydrogenase 41
glyceraldehyde-3-phosphate dehydrogenase 40
glyceraldehyde-3-phosphate dehydrogenase 40
phosphoenolpyruvate carboxykinase 38
phosphoenolpyruvate carboxykinase 37
succinyl-CoA synthetase 37
SCS 37
gamma-glutamyl transpeptidase 35
phosphoenolpyruvate carboxykinase 35
NADPH oxidase 33
AMP-activated protein kinase 33
xanthine oxidase 32
isocitrate lyase 30
alcohol dehydrogenase 29
3-hydroxyacyl-CoA dehydrogenase 27
glutathione S-transferase 26
3-hydroxyacyl-CoA dehydrogenase 26
6-phosphogluconate dehydrogenase 26
6-phosphogluconate dehydrogenase 26
pyruvate carboxylase 25
PAL 25
trypsin 25
beta-galactosidase 25
ACE 23
PDH 22
lysozyme 20
adenylate kinase 19
leucine aminopeptidase 19
nucleotidase 19
RNase 19
tyrosine hydroxylase 19
lactic acid dehydrogenase 18
proteasome 18
lactic acid dehydrogenase 18
caspase-8 18
hexosaminidase 18
NADPH oxidase 18
glutamine synthetase 17
lipase 17
aldehyde dehydrogenase 17
acyl-CoA dehydrogenase 17
ubiquinol-cytochrome c oxidoreductase 16
CPT 16
prolyl hydroxylase 16
adenylate cyclase 16
phosphoglucose isomerase 16
invertase 16
AMPK 16
demethylase 16
RNA polymerase 15
nitrate reductase 15
triphosphatase 15
nitrate reductase 15
caspase-9 15
malate synthase 15
aldehyde dehydrogenase 15
AMPK 15
aldehyde dehydrogenase 14
nitrate reductase 14
nitrate reductase 14
aldehyde dehydrogenase 14
nitrate reductase 14
phosphatidylinositol 3-kinase 14
dihydroorotate dehydrogenase 14
NO synthase 14
protein kinase C 14
nitrate reductase 14
aldehyde dehydrogenase 14
dihydroorotate dehydrogenase 14
collagenase 13
phospholipase A2 13
luciferase 13
carbonic anhydrase 13
NOS 12
Mg2+-ATPase 12
MDH 12
phosphodiesterase 12
glycerol 3-phosphate dehydrogenase 12
MDH 12
alpha-glucosidase 12
lipoprotein lipase 12
calcineurin 12
ACS 12
renin 12
acyl-CoA dehydrogenase 11
transhydrogenase 11
hydrogenase 11
hydrogenase 11
MPP 11
phosphoenolpyruvate carboxylase 10
carboxylesterase 10
p-nitrophenylphosphatase 10
glucokinase 10
alpha-mannosidase 10
succinic semialdehyde dehydrogenase 10
arginase 9
sorbitol dehydrogenase 9
PARP 9
IscS 9
sucrase 9
phosphoglucomutase 9
more...
Compound
oxygen 1172
ATP 646
DNA 616
Dec 564
NADH 545
glucose 519
iron 367
calcium 271
succinic acid 268
sodium 264
glutamate 261
phosphate 258
ubiquinone 257
NAD 250
water 234
NAD 204
ADP 198
ADP 182
ADP 182
2-oxoglutarate 151
hydrogen 146
Clin 137
GSH 128
GSH 128
acetate 127
nicotinamide 115
TCA 103
NADPH 96
NADPH 95
NADP 94
FAD 91
cysteine 89
potassium 87
ubiquinol 87
cyanide 85
nitrogen 84
MTT 83
nitric oxide 82
ethanol 82
H2O2 81
sulfate 80
glycerol 80
CO2 79
His 75
CoA 74
salt 73
copper 73
dicarboxylic acid 71
alanine 68
arginine 67
tyrosine 62
NPA 59
leucine 56
BNP 55
bromide 54
glutamine 52
pentose 52
pentose 52
pentose 52
pentose 52
ammonium 49
Lactate 48
TNF 48
manganese 47
zinc 47
isocitrate 46
galactose 45
Triton X-100 45
Mg2+ 44
methionine 44
SDS 43
lysine 43
phenazine 43
Malonate 42
nitrate 42
Cytochrome c 41
GABA 41
GABA 41
urea 40
succinic acid 39
succinic acid 39
succinic acid 39
succinic acid 39
coenzyme Q10 39
serine 39
CoQ 35
NMDA 35
AMP 34
cadmium 33
COX 32
acetic acid 32
aldehyde 28
EDTA 28
EDTA 28
Fumarate 28
Glycogen 27
ammonia 27
acetyl-CoA 27
Phe 27
PAS 27
alcohol dehydrogenase 27
proline 26
Rotenone 26
PEG 26
superoxide radical 25
DDP 25
N-acetylcysteine 25
cAMP 24
GTP 24
noradrenaline 24
glucose-6-phosphate 24
Cardiol 24
Coenzyme Q10 23
selenium 23
oxalacetate 23
threonine 23
PDH 22
phosphocreatine 21
Cyt 21
Asp 20
malic acid 20
creatinine 20
MPTP 20
MDA 20
GSSG 19
phosphorus 19
DNP 19
uridine 19
pyridine 19
hexose 18
hexose 18
iodine 18
Insulin 18
Glutamate 18
pyrimidine 18
hexose 18
pyrimidine 18
L-carnitine 18
gamma-aminobutyric acid 18
hexose 18
glutamic acid 17
silver 17
tryptophan 17
Gly 17
acetone 17
Adriamycin 17
PEG 17
pyrene 16
FMN 16
malonic acid 16
nickel 16
aldehyde 16
tryptophan 16
tryptophan 16
tryptophan 16
NH2 15
Chlorophyll 15
heptyl 15
acetaldehyde 15
heptyl 15
more...