Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:1.3.5.1 (succinate dehydrogenase)
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Histochemical study of some enzymatic systems was conducted in various form of goiter. A study was made of the thyroid gland tissue obtained during the operation in 96 patients. Euthyrosis was accompanied by a decrease in the succinic dehydrogenase, cytochromoxidase, iodide peroxidase, acid and alkaline phosphatase activity. As to thyrotoxic goiter - it displayed an increase in the activity of these enzymes and desquamation of the follicular epithelium; the rejected cells possessed a high acid phosphatase activity. In comparison with thyrotoxic goiter, Askinazi's cell count was increased in the euthyroid macrofollicular nodular and diffuse goiter.
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PMID:[Histochemical characteristics of some oxidation-reduction hydrolytic enzymes in different forms of goiter]. 19 Jun 4