Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.3.1.51 (HDR)
 605 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
ZEP2 15.7
HDR 15.3
Transmembrane channel-like protein 1 13.7
DGCR2 13.2
cysteine/histidine-rich 1 12.5
NAPOR 11.9
VDP 11.8
ASBT 11.2
CUGBP2 11.0
EMX1 10.9
GGPPS 10.9
JAM3 10.4
IDI1 10.4
CCD1 10.4
GATA3 10.2
PG-Lb 10.2
HRD 9.7
HDS 9.6
BFP 9.6
FGF20 9.4
Period 3 9.3
D53 9.3
RW1 9.1
CELF2 9.1
PGM3 9.1
PKLR 9.1
HAR 9.0
MVK 8.9
EXO1 8.9
V75 8.9
Interleukin-21 8.8
DNA2 8.8
phosphomevalonate kinase 8.7
PIF1 8.5
HSD17B4 8.5
HOXB13 8.4
CtIP 8.4
MOZ 8.4
TLD 8.3
myosin VIIa 8.2
FANCI 8.2
CSN2 8.1
RPGR 8.1
serrate 8.0
CS-1 7.9
LIG4 7.8
PEG10 7.8
MEP 7.7
FLS 7.6
US1 7.5
RAD52 7.3
FLU 7.3
Period 1 7.3
Citrate synthase 7.2
ALC 7.2
LIS1 7.2
prestin 7.2
NPL 7.2
IPP 7.2
DYRK1A 7.2
AMT 7.2
Tip60 7.2
SF2 7.2
RS1 7.2
DCT 7.1
CORT 7.1
IIS 7.0
PAM 6.9
Cx30 6.9
D10 6.9
FANCD2 6.9
PTB 6.9
EOS 6.8
CMK 6.8
XRCC3 6.7
TEC 6.6
GATA-3 6.6
Interleukin-7 6.5
version 3 6.5
beta globin 6.4
PTA 6.3
NSF 6.1
IGH 6.1
p15 6.1
PSA 6.1
MDD 6.1
ESX 6.0
Rad50 6.0
NTM 6.0
HPRT 6.0
HLA-D 6.0
MSD 5.9
MECP2 5.9
CRT 5.9
fetal kidney 5.9
ABS 5.9
MIM 5.9
HDAC3 5.9
Lag 5.9
zinc finger transcription factor 5.9
DNA polymerase alpha 5.8
STAR 5.8
scatter factor 5.8
PTP 5.8
Tyrosinase 5.8
RAD51 5.7
period 2 5.7
LOX 5.7
HDAC2 5.7
Interleukin-3 5.7
ERCC1 5.6
GJB2 5.6
SWI 5.6
proinsulin 5.6
Ku70 5.5
NPC 5.4
HAT 5.4
prostate-specific antigen 5.4
PTC 5.4
antichymotrypsin 5.4
RCC 5.4
transforming growth factor-beta 1 5.3
phenylalanine hydroxylase 5.3
NRC 5.2
HLA-C 5.2
IGF2 5.1
ESR1 5.1
AE3 5.0
PU.1 5.0
mutant p53 5.0
factor H 4.9
A-T 4.9
FBS 4.9
RNase III 4.9
RACE 4.9
Rad51 4.9
DNA binding protein 4.8
CIE 4.8
CPU 4.7
DIC 4.7
FISH 4.7
ADR 4.7
NRAS 4.7
ara 4.6
ASD 4.6
reductase 4.6
MDS 4.6
Genesis 4.6
STS 4.6
manganese superoxide dismutase 4.6
HDAC1 4.5
HLA-B27 4.5
CD57 4.5
AE1 4.5
HDAC 4.4
ESR 4.4
RNP 4.4
HT3 4.4
zinc finger 4.3
prostate specific antigen 4.3
endonuclease 4.3
antioxidant enzyme 4.3
HLA-B 4.3
PAP 4.3
hairy 4.3
p13 4.3
NADP+ 4.3
CBP 4.2
ACP 4.1
chromogranin A 4.1
Rett syndrome 4.1
CML 4.0
RET 4.0
NK1 4.0
cytochrome c oxidase 4.0
EBP 4.0
H-ras 4.0
THC 3.8
glutamic acid decarboxylase 3.8
H2AX 3.7
Men 3.7
ISA 3.7
neuron-specific enolase 3.7
natural killer cell 3.7
MDM2 3.7
helicase 3.6
p300 3.6
CAD 3.6
adenosine receptor 3.5
CCD 3.5
NO3 3.5
alpha-amylase 3.4
MYC 3.3
ENT 3.3
integrase 3.3
HLA-A 3.3
Xin 3.3
CEA 3.3
ATM 3.2
IL-3 3.1
MRI 3.1
synaptophysin 3.1
interleukin-4 3.1
CD56 3.0
DSC 3.0
thymus 3.0
atrial natriuretic peptide 3.0
KRAS 3.0
TGA 3.0
Hua 3.0
PTH 3.0
ribonucleoprotein 2.9
MAP 2.9
SAR 2.8
macrophage colony-stimulating factor 2.8
interleukin-2 2.8
metallothionein 2.7
TNM 2.7
tyrosinase 2.7
parathyroid hormone 2.7
IL-1 beta 2.6
ACE 2.6
B12 2.6
GM-CSF 2.5
Polymerase 2.5
BRCA1 2.5
COD 2.5
GST 2.5
glutathione reductase 2.5
BRAF 2.5
RNase 2.4
PARP 2.3
NHS 2.3
FDG 2.2
osteocalcin 2.2
DNA polymerase 2.1
proliferating cell nuclear antigen 2.0
androgen receptor 1.9
tumor necrosis factor alpha 1.9
TGF-beta 1.9
hole 1.8
fibrinogen 1.8
p53 1.8
thyroid hormone 1.7
casein 1.6
polypeptide 1.5
Bot 1.4
ESI 1.4
lymphoid 1.4
nodal 1.2
vasopressin 1.2
myosin 1.2
PI3K 1.2
superoxide dismutase 1.1
NADPH 1.1
estrogen receptor 0.9
She 0.9
Mol 0.8
TNF 0.8
hemoglobin 0.7
Pol 0.6
AMP 0.4
HLA 0.4
collagen 0.3
peroxidase 0.3
IFN 0.3
histone 0.2
Sep 0.2
catalase 0.2
Rec -0.1
fused -0.1
tumor necrosis factor -0.2
IL-6 -0.2
lipopolysaccharide -0.2
cytokine -0.5
Disease
DGS2 14.3
recurrent oropharyngeal cancer 13.1
monosomy 10p 12.7
HRD 10.8
tracheal cancer 10.7
PDR 10.4
hypophosphaturia 10.3
pediatric soft tissue sarcoma 10.0
pseudopapilledema 10.0
recurrent esophageal cancer 9.8
Kenny-Caffey syndrome 9.6
BPS 9.6
hypoparathyroidism 9.5
vaginal cancer 9.2
urethral cancer 9.1
BED 9.0
Sever 9.0
proliferative diabetic retinopathy 8.9
recurrent rectal cancer 8.8
Osteoradionecrosis 8.8
Deafness 8.8
recurrent endometrial cancer 8.8
X-linked retinoschisis 8.7
DiGeorge syndrome 8.7
OAR 8.6
Jacobsen syndrome 8.6
recurrent cervical cancer 8.6
proctitis 8.4
FANCI 8.2
DBA2 8.1
Klatskin 7.9
DIN 7.7
DIN 7.7
tetany 7.7
velocardiofacial syndrome 7.6
deafness 7.6
AOS 7.5
penile cancer 7.4
recurrent prostate cancer 7.3
adenomatous polyp 7.1
stage III NSCLC 7.1
carcinoma of the esophagus 7.0
marasmus 6.9
oropharyngeal cancer 6.9
PAM 6.9
EOS 6.8
EOS 6.8
congenital deafness 6.8
Spencer 6.7
TEC 6.6
oropharyngeal squamous cell carcinoma 6.5
LIS1 6.5
urethra 6.4
carcinoma of the cervix 6.4
cleft lip/palate 6.4
cervical cancer 6.2
Congenital heart disease 6.1
PSA 6.1
MSD 5.9
Cholangiocarcinoma 5.9
head and neck cancer 5.9
ABS 5.9
pseudohypoparathyroidism 5.9
ABS 5.8
Cholangiocarcinoma 5.7
PTP 5.7
gynecologic cancer 5.7
uterine cancer 5.6
cystitis 5.6
cervical squamous cell carcinoma 5.6
sensorineural hearing loss 5.6
prostate cancer 5.4
Addison's disease 5.4
endometrial cancer 5.4
Thyroid cancer 5.4
Addison's disease 5.3
Fanconi 5.3
residual disease 5.3
dysplasia 5.2
severe mental retardation 5.2
Prostate Cancer 5.1
uveal melanoma 5.1
HCG 5.0
uterine cervix 5.0
calcinosis 4.9
FBS 4.9
CIE 4.8
renal tubular acidosis 4.7
NPC 4.7
hyperphosphatemia 4.6
Wiskott-Aldrich syndrome 4.6
HLA-B27 4.5
MDS 4.4
hypopituitarism 4.4
Sweet 4.4
STS 4.4
adult T-cell leukemia/lymphoma 4.4
Bladder 4.4
Bladder 4.4
Bladder 4.4
prostatic adenocarcinoma 4.4
viral diarrhea 4.3
hemoglobinopathies 4.3
rectal cancer 4.3
esophageal cancer 4.2
oral cancer 4.2
bronchospasm 4.2
ACP 4.2
interstitial pneumonia 4.1
dysphagia 4.1
phenylketonuria 4.0
Poland 4.0
sclera 4.0
Rett syndrome 4.0
lichen 3.9
vagina 3.9
IBM 3.9
bronchogenic carcinoma 3.9
papillary thyroid cancer 3.7
transitional cell carcinoma 3.7
flutter 3.7
Rectum 3.7
Rectum 3.7
Rectum 3.7
Rectum 3.7
CEM 3.6
carcinoma 3.6
ATM 3.6
benign tumor 3.6
ileus 3.6
esophageal cancer 3.6
genetic disorder 3.5
renal insufficiency 3.5
thymoma 3.5
CCD 3.5
ureter 3.4
lymphedema 3.4
lymphopenia 3.4
neoplastic transformation 3.4
CCD 3.4
developmental disabilities 3.4
trisomy 3.3
cleft palate 3.3
decubitus 3.3
lung metastases 3.3
vitamin D deficiency 3.2
non-small cell lung cancer 3.2
esophagitis 3.2
prolapse 3.2
lung carcinoma 3.1
Brown 3.1
psychological stress 3.1
skin cancer 3.1
bone metastases 3.0
small cell lung cancer 3.0
renal disease 3.0
mammary tumor 3.0
incontinence 3.0
Esophageal 3.0
basal cell carcinoma 3.0
atrial septal defect 2.9
duodenal ulcer 2.9
mesothelioma 2.9
squamous cell carcinoma 2.8
cerebral infarction 2.8
metastases 2.8
nystagmus 2.8
SAR 2.8
mental retardation 2.7
mental retardation 2.7
adenocarcinoma 2.6
liver metastases 2.6
thyroid cancer 2.6
sarcoma 2.6
graft-versus-host disease 2.5
pneumonia 2.5
glioblastoma 2.5
cytomegalovirus 2.5
tumor 2.5
primary tumor 2.4
tumor progression 2.4
middle ear 2.4
lung cancer 2.4
fits 2.3
renal failure 2.3
NHS 2.3
epithelial ovarian cancer 2.2
sickle cell disease 2.2
brain tumor 2.1
periodontitis 2.1
rare disease 2.1
anemia 2.0
Thorax 1.9
parkinsonism 1.9
myelodysplastic syndrome 1.8
glioma 1.8
breast cancer 1.7
cancer 1.7
autism 1.7
uterus 1.6
colorectal cancer 1.6
Best 1.6
mole 1.6
chronic myeloid leukemia 1.5
psoriasis 1.3
type 1 diabetes 1.3
adenoma 1.3
mole 1.3
major depressive disorder 1.3
renal cell carcinoma 1.2
malaria 1.2
melanoma 1.2
neuropathy 1.2
cornea 1.1
dehydration 1.1
lymphoma 1.1
MCF 0.9
influenza 0.9
cataract 0.9
tumor growth 0.8
hepatitis 0.8
Hodgkin's disease 0.8
cold 0.8
carcinogenesis 0.7
heart disease 0.6
immunodeficiency 0.6
multiple myeloma 0.5
gastric cancer 0.5
West 0.5
cirrhosis 0.3
multiple sclerosis 0.3
coronary artery disease 0.2
SEM 0.2
sepsis 0.0
rheumatoid arthritis -0.0
tumorigenesis -0.1
sepsis -0.2
cardiovascular disease -0.3
heart failure -0.5
asthma -0.7
diabetes -0.8
stroke -1.5
HIV -1.7
Symptom
clumsiness 6.6
leg edema 6.3
hemoptysis 6.3
hypertonia 5.4
skin irritation 4.6
stridor 4.5
Wind 4.3
asthenia 4.3
cough 4.1
bone pain 4.1
dyspnea 3.9
ENT 3.3
collapse 3.2
hypotonia 3.2
discomfort 2.8
discomfort 2.7
anesthesia 2.5
constipation 2.4
tremor 1.5
nausea 1.2
fatigue 1.0
analgesia 0.9
pain 0.5
seizures 0.4
Drug
Calcium gluconate 10.1
Ethyol 8.9
EDR 7.3
Amifostine 7.2
Lugol 7.1
Iohexol 6.7
Carotenoid 6.2
Vitamin B12 5.4
Alanine 5.2
VCR 5.1
PTC 4.9
ADR 4.7
MDS 4.6
Alliance 4.3
niacin 3.8
Histamine 3.2
Bifidobacterium 3.2
PTH 2.9
MAP 2.7
ENT 2.6
TiO2 2.2
CSF 0.8
Cardiovasc -1.9
Enzyme
HDR 15.7
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 11.6
zeaxanthin epoxidase 9.1
4CL 7.4
reductoisomerase 7.2
NPL 6.9
PAM 6.8
MDR 6.2
PTA 6.0
GAS 5.8
prostate-specific antigen 5.5
hypoxanthine-guanine phosphoribosyltransferase 5.4
phenylalanine hydroxylase 5.2
ascorbate peroxidase 5.2
DCF 4.7
phytase 4.7
phytase 4.7
glucoamylase 4.6
BMT 4.3
endonuclease 4.3
CAD 3.6
CAD 3.6
CAD 3.5
alpha-amylase 3.3
glucose oxidase 3.3
DNA polymerase 3.2
MAP 2.8
tyrosinase 2.5
glutathione reductase 2.5
PARP 2.0
ERK 1.7
RNase 1.7
RNase 1.6
ACE 1.5
glutathione S-transferase 1.2
superoxide dismutase 0.8
luciferase 0.5
focal adhesion kinase 0.3
catalase -0.1
peroxidase -0.3
protein kinase -0.6
Compound
1-vinyl-2-pyrrolidinone 10.4
EBT 9.4
DHI 9.3
EOC 8.4
Methyl jasmonate 7.9
9-octadecenoic acid 7.9
MEP 7.7
dGMP 7.6
MEP 7.6
2-methoxyethanol 7.5
DMPP 7.5
isopentenyl diphosphate 7.3
Amifostine 7.1
Tranexamic acid 6.9
EOS 6.8
TEC 6.6
CMK 6.5
Zearalenone 6.5
PAM 6.4
DFS 6.3
R 2 6.2
RELA 6.1
LCR 6.0
MDR 6.0
PAM 5.8
PAM 5.8
Artemisinin 5.7
RU-486 5.6
TTC 5.5
Cobalt 5.5
Ribavirin 5.4
TBI 5.3
Alanine 5.3
Interleukin-2 5.2
tungsten 5.2
DMP 4.8
DOC 4.6
Hoechst 33342 4.5
palmitic acid 4.4
Malondialdehyde 4.3
PAP 4.3
PAP 4.0
PAP 4.0
PAP 4.0
kaempferol 3.5
Lithium 3.5
DAD 3.4
NO3 3.4
HCO 3.3
strontium 3.3
salicylic acid 3.2
Histamine 3.2
butyric acid 3.2
ADR 3.1
butyric acid 3.1
butyric acid 2.9
cobalt 2.9
5-FU 2.9
iodine 2.9
6-12 2.9
dUTP 2.8
PMA 2.7
formaldehyde 2.7
TNM 2.7
hydroxide 2.7
Progesterone 2.6
GMP 2.5
Sodium 2.5
MAP 2.5
formaldehyde 2.4
titanium 2.4
NADP 2.2
PMA 2.1
COS 2.1
uridine 2.0
phenol 2.0
Off 1.9
zinc 1.8
barium 1.7
DNA 1.7
nicotinamide 1.7
glutamic acid 1.7
water 1.6
manganese 1.6
Optimal 1.6
fluorine 1.6
cysteine 1.5
His 1.4
pyrene 1.4
alanine 1.2
NADPH 1.1
NADPH 1.1
phosphate 1.1
nitrate 1.0
vitamin D 0.9
PEG 0.9
TNF 0.8
MTT 0.7
Pac 0.6
cadmium 0.6
Clin 0.5
PEG 0.4
acetate 0.4
calcium 0.3
AMP 0.3
silicon 0.3
Phe 0.0
Dec -0.0
sodium -0.1
sulfate -0.1
salt -0.1
silver -0.2
leucine -0.2
urea -0.3
serine -0.3
glutamate -0.5
oxygen -0.5
nitrogen -0.6
CO2 -0.8
copper -0.8
potassium -0.9
arginine -0.9
iron -1.4
hydrogen -2.0
Cardiol -2.2
glucose -2.5