Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.3.1.51 (
HDR
)
605
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Artemisinin is the first choice for malaria treatment. The plastidial MEP pathway provides 5-carbon precursors (
IPP
and its isomer DMAPP) for the biosynthesis of isoprenoid (including artemisinin). Hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (
HDR
) is the last enzyme involved in the MEP pathway, which catalyzes HMBPP to form
IPP
and DMAPP. In this study, we isolated the full-length cDNA of
HDR
from
...
PMID:[Molecular cloning and functional characterization of the gene encoding hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase gene from Artemisia annua L.]. 2990 29
