Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.2.7.5 (
AOR
)
1,763
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The association of candidate genes and psychological symptoms of depression, anxiety, and stress among women with gestational diabetes mellitus (GDM) in Malaysia was determined in this study, followed by the determination of their odds of getting psychological symptoms, adjusted for socio-demographical background, maternal, and clinical characteristics. Single nucleotide polymorphisms (SNPs) recorded a significant association between SNP of
EPHX2
(rs17466684) and depression symptoms (
AOR
= 7.854, 95% CI = 1.330-46.360) and stress symptoms (
AOR
= 7.664, 95% CI = 1.579-37.197). Associations were also observed between stress symptoms and SNP of
OXTR
(rs53576) and (
AOR
= 2.981, 95% CI = 1.058-8.402) and SNP of
NRG1
(rs2919375) (
AOR
= 9.894, 95% CI = 1.159-84.427). The SNP of
EPHX2
(rs17466684) gene polymorphism is associated with depression symptoms among Malaysian women with GDM. SNP of
EPHX2
(rs17466684),
OXTR
(rs53576) and
NRG1
(rs2919375) are also associated with stress symptoms.
...
PMID:Association Analysis of 14 Candidate Gene Polymorphism with Depression and Stress among Gestational Diabetes Mellitus. 3180 Dec 86
