Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.2.7.5 (
AOR
)
1,763
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The capacity for colonoscopy is limited and a method to prioritize patients for diagnostic colonoscopy is needed in health care centers. A retrospective cross-sectional cohort study was carried out in county and community endoscopy centers, which included 1,065 county and 279 community patients aged > or = 40 years undergoing diagnostic colonoscopy. We constructed a risk profile for proximal advanced neoplasms on diagnostic colonoscopy at the county center based on the size of the regression coefficients for independent risk factors from logistic regression. An advanced neoplasm was defined as one of size > or = 1 cm or containing villous histology, high-grade dysplasia, or cancer. In our county colonoscopy population (n = 929 after exclusions), the stepwise logistic regression analysis identified age > or = 60 years (adjusted odds ratio [
AOR
]: 2.60; 95% confidence interval [CI]:1.14, 6.14),
iron deficiency anemia
(
AOR
: 4.74; 95% CI: 2.07, 11.34), and an advanced neoplasm in the recto-sigmoid (
AOR
: 6.01; 95% CI: 2.02, 16.00) as the statistically significant predictors of an advanced proximal neoplasm. In the county population, the prevalence rates of an advanced proximal neoplasm and proximal high-grade dysplasia/cancer in the low-risk group were 0.71% (95% CI: 0.15, 2.05) and 0.24% (95% CI: 0.01, 1.31), respectively. Avoiding colonoscopy in this group would increase the capacity for colonoscopy by 46% in the higher risk groups. In a disparate community population (n = 237 after exclusions), this scoring system had a goodness-of-fit test showing high concordance (P = 0.51). This clinical profile stratified the risk for an advanced neoplasm proximal to the sigmoid in patients undergoing diagnostic colonoscopy. It identified a large subset of low-risk patients.
...
PMID:A risk profile for advanced proximal neoplasms on diagnostic colonoscopy. 1853 6
Background. Globally, about 47.4% of children under five are suffering from anemia. In Ethiopia, 60.9% of children under two years are suffering from anemia. Anemia during infancy and young childhood period is associated with poor health and impaired cognitive development, leading to reduced academic achievement and earnings potential in their adulthood life. However, there is scarcity of information showing the magnitude of
iron deficiency anemia
among young children in Ethiopia. Therefore, this study aimed at assessing prevalence and associated factors of
iron deficiency anemia
among children under two (6-23 months). Methods. Institution based cross-sectional study was carried out from March to May, 2014, at Tsitsika Health Center in Wag-Himra Zone, Northeast Ethiopia. Systematic random sampling technique was employed. Automated hemoglobin machine was used to determine the hemoglobin level. Socioeconomic and demographic data were collected by using a pretested and structured questionnaire. Binary logistic regression analysis was used to identify associated factors and odds ratio with 95% CI was computed to assess the strength of association. Results. Total of 347 children participated in this study. The overall prevalence of anemia was 66.6%. In multivariate logistic regression analysis, male sex (
AOR
= 3.1 (95% CI: 1.60-5.81)), 9-11 months of age (
AOR
= 9.6 (95% CI: 3.61-25.47)), poor dietary diversity (
AOR
= 3.2 (95% CI: 1.35-7.38)), stunting (
AOR
= 2.7 (95% CI: 1.20-6.05)), diarrhea (
AOR
= 4.9 (1.63-14.59)), no formal education (
AOR
= 2.6 (95% CI: 1.26-5.27)), early initiation of complementary food (
AOR
= 11.1 (95% CI: 4.08-30.31)), and lowest wealth quintile (
AOR
= 3.0 (95% CI: 1.01-8.88)) were significantly associated with anemia. Conclusion. The overall prevalence of anemia among children who aged 6-23 months has sever public health importance in the study area. Integrated efforts need to be prioritized to improve health as well as appropriate infant and young child feeding practice among children under.
...
PMID:Factors Associated with Anemia among Children Aged 6-23 Months Attending Growth Monitoring at Tsitsika Health Center, Wag-Himra Zone, Northeast Ethiopia. 2610 86
Background. In Ethiopia, higher proportions of pregnant women are anemic. Despite the efforts to reduce
iron deficiency anemia
during pregnancy, only few women took an iron supplement as recommended. Thus, this study aimed to assess compliance with iron-folate supplement and associated factors among antenatal care attendant mothers in Misha district, South Ethiopia. Method. Community based cross-sectional study supported with in-depth interview was conducted from March 1 to March 30, 2015. The sample size was determined using single population proportion to 303. Simple random sampling technique was used to select the study participants. Bivariate and multivariable logistic regression analyses were employed to identify factors associated with compliance to iron-folate supplement. Results. The compliance rate was found to be 39.2%. Mothers knowledge of anemia (
AOR
= 4.451, 95% CI = (2.027,9.777)), knowledge of iron-folate supplement (
AOR
= 3.509, 95% CI = (1.442,8.537)), and counseling on iron-folate supplement (
AOR
= 4.093, 95% CI = (2.002,8.368)) were significantly associated with compliance to iron-folate supplement. Conclusions. Compliance rate of iron-folate supplementation during pregnancy remains very low. This study showed that providing women with clear instructions about iron-folate tablet intake and educating them on the health benefits of the iron-folate tablets can increase compliance with iron-folate supplementation.
...
PMID:Compliance with Iron-Folate Supplement and Associated Factors among Antenatal Care Attendant Mothers in Misha District, South Ethiopia: Community Based Cross-Sectional Study. 2683 73