Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.17.3.2 (
xanthine oxidase
)
8,383
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
xanthine oxidase
7867
superoxide dismutase
1704
catalase
1347
Sep
595
xanthine oxidoreductase
440
glutathione peroxidase
383
xanthine dehydrogenase
364
Mol
349
GSH
307
nitric oxide synthase
306
NADPH
282
SOD
278
ATP
260
NADH
254
myeloperoxidase
242
cytochrome c
225
aldehyde oxidase
199
lactate dehydrogenase
191
Superoxide dismutase
189
cyclooxygenase
163
peroxidase
158
microsomal
157
NAD
143
Catalase
135
tumor necrosis factor
126
lipopolysaccharide
122
adenosine deaminase
119
glutathione reductase
119
lipoxygenase
116
NMR
115
ADP
109
albumin
108
ROS
105
insulin
104
cytochrome P450
98
ATPase
96
inducible nitric oxide synthase
94
EPR
93
cytokine
90
reductase
87
TNF
86
ESR
85
FAD
80
AMP
77
hemoglobin
75
collagen
72
antioxidant enzyme
72
cytochrome P-450
67
caspase-3
66
cytochrome
66
serum albumin
63
alkaline phosphatase
61
purine nucleoside phosphorylase
58
aspartate aminotransferase
57
oxidoreductase
56
IL-6
56
angiotensin II
52
endothelial nitric oxide synthase
52
gut
52
glucose-6-phosphate dehydrogenase
51
NAD+
49
MnSOD
49
heme oxygenase-1
48
vascular endothelium
47
p38
47
TNF-alpha
47
spermatozoa
46
sulfite oxidase
46
phospholipase A2
45
thymus
45
ornithine decarboxylase
45
ferritin
45
endoplasmic reticulum
43
CO2
43
tyrosinase
43
aldehyde dehydrogenase
43
XDH
41
amylase
41
flavoprotein
40
creatine kinase
37
more...
Disease
ischemia
706
gout
361
hyperuricemia
357
GSH
307
cancer
273
hypertension
199
diabetes
198
tumor
187
atherosclerosis
139
heart failure
103
arthritis
89
cardiovascular disease
84
myocardial ischemia
81
depression
78
carcinogenesis
74
renal disease
70
myocardial infarction
67
NAME
64
obesity
59
stroke
51
metabolic syndrome
48
cerebral ischemia
48
sepsis
48
sepsis
46
cold
45
hyperglycemia
44
carcinoma
44
Alzheimer's disease
39
hypercholesterolemia
39
acute pancreatitis
38
type 2 diabetes
37
SDS
37
SEM
35
pulmonary edema
32
renal ischemia
30
pancreatitis
30
renal failure
29
hepatocellular carcinoma
28
vascular disease
26
tophi
24
pulmonary hypertension
23
hyperlipidemia
23
leukemia
23
renal impairment
23
rheumatoid arthritis
22
immunodeficiency
22
preeclampsia
22
adult respiratory distress syndrome
22
asthma
21
acute myocardial infarction
21
hepatitis
21
plaque
20
Parkinson's disease
20
mole
19
proteinuria
19
mole
19
HIV
18
acute renal failure
18
melanoma
18
tumorigenesis
18
breast cancer
18
congestive heart failure
17
influenza
17
coronary artery disease
17
urolithiasis
17
malaria
16
chronic granulomatous disease
16
renal insufficiency
16
tumor lysis syndrome
15
colitis
14
prostate cancer
14
diabetic nephropathy
14
inflammatory bowel disease
14
rheumatism
14
MCF
14
ulcerative colitis
13
virus infection
13
glomerulosclerosis
13
ventricular fibrillation
13
coronary heart disease
13
more...
Symptom
pain
28
hyperoxia
27
anesthesia
26
seizures
18
fatigue
17
respiratory distress
16
functional recovery
13
diarrhea
12
angina
11
starvation
10
hypothermia
10
exhaustion
9
skin damage
7
acidity
6
headache
6
vomiting
5
collapse
5
weakness
5
nausea
5
erythema
5
arthralgia
4
myalgia
3
anorexia
3
abdominal pain
3
colic
3
cachexia
3
overweight
3
oliguria
3
hypercapnia
3
flushing
3
dizziness
3
Anoxia
3
Ill
2
renal colic
2
twitching
2
agitation
2
autodigestion
2
dry eye
2
acute stress
2
sleepiness
2
dystonia
1
hyperesthesia
1
memory loss
1
skin irritation
1
pelvic pain
1
polyuria
1
hypocapnia
1
tonic-clonic seizure
1
hypertonia
1
discomfort
1
shortness of breath
1
asthenia
1
discomfort
1
hypotonia
1
prostration
1
muscle rigidity
1
hepatosplenomegaly
1
chest pain
1
leg edema
1
exertional dyspnea
1
athetosis
1
neuralgia
1
paresis
1
HSA
1
No adverse effect
1
spasm
1
eds
1
rigors
1
cough
1
catarrh
1
ketonuria
1
disturbed balance
1
thinning
1
throat irritation
1
Macula
1
Drug
NADH
251
ascorbate
226
vitamin E
137
ROS
105
Cardiovasc
88
FAD
80
Febuxostat
80
caffeine
69
Indomethacin
33
NBT
32
Dermatol
32
Ethanol
26
Nitric Oxide
25
lysine
24
Glutathione
22
nitroglycerin
19
Vitamin E
19
FeCl3
18
Adriamycin
15
Desferal
14
Desferal
14
IFN-gamma
14
Mutagen
12
CaCl2
11
CaCl2
11
Albumin
11
Rasburicase
11
CaCl2
11
Leaf
9
L-tyrosine
9
Methylene blue
9
Ringer's solution
9
Y-700
9
IL-2
8
Angiotensin II
8
Nephron
8
CSF
8
Monit
8
Fructose
7
Gel
7
Acacia
7
Adenosine deaminase
7
balanced salt solution
7
Vitamin K
7
Photofrin
6
Rebamipide
6
Propofol
6
Spectrum
6
MAP
6
Captopril
6
Sodium nitroprusside
6
Myricetin
6
Nephron
6
Omeprazole
5
lactose
5
Aloe
5
BH4
5
THF
5
Rasburicase
5
Rutin
5
Fluorescein
5
Arsenic trioxide
5
Cimetidine
4
Moco
4
NH3
4
Heme
4
Ouabain
4
pyridoxal phosphate
4
CTX
4
niacin
4
ETA
4
Glycyrrhiza
4
TMX
4
Cimetidine
4
Portal
3
Fraction
3
ICI
3
MgSO4
3
Zinc sulfate
3
APD
3
more...
Enzyme
xanthine oxidase
8383
superoxide dismutase
1877
catalase
1358
xanthine dehydrogenase
750
NADPH oxidase
441
peroxidase
401
glutathione peroxidase
390
NADPH oxidase
359
aldehyde dehydrogenase
234
lactate dehydrogenase
205
aldehyde oxidase
189
NO synthase
137
glucose oxidase
133
glutathione reductase
122
adenosine deaminase
119
adenosine deaminase
119
lipoxygenase
117
ATPase
109
uricase
100
mitogen-activated protein kinase
97
protein kinase C
85
aspartate aminotransferase
68
NQO1
68
alanine aminotransferase
61
alkaline phosphatase
61
phospholipase A2
59
creatine kinase
57
glucose-6-phosphate dehydrogenase
56
purine nucleoside phosphorylase
55
glutathione S-transferase
55
aldehyde dehydrogenase
54
caspase-3
50
diaphorase
50
NOS
50
nitrate reductase
47
nitrate reductase
47
nitrate reductase
47
sulfite oxidase
47
nitrate reductase
47
nitrate reductase
46
nitrate reductase
46
sulfite oxidase
46
tyrosinase
45
ornithine decarboxylase
45
aldehyde dehydrogenase
43
aldehyde dehydrogenase
43
aldehyde dehydrogenase
43
complex I
42
CPR
42
protein kinase
42
monoamine oxidase
40
alcohol dehydrogenase
39
trypsin
38
elastase
38
5'-nucleotidase
35
guanylate cyclase
33
succinate dehydrogenase
32
guanase
31
hypoxanthine-guanine phosphoribosyltransferase
31
gamma-glutamyl transpeptidase
30
ceruloplasmin
30
renin
29
collagenase
28
acetylcholinesterase
26
ERK
26
nitrite reductase
25
nitrite reductase
25
nitrite reductase
25
heme oxygenase
25
ACE
23
N-acetyltransferase
22
phosphodiesterase
22
NADPH-diaphorase
21
diaphorase
21
thrombin
20
lipase
20
NADH dehydrogenase
18
cytochrome oxidase
18
alpha-glucosidase
16
aconitase
16
more...
Compound
oxygen
2951
hydrogen
965
H2O2
794
nitric oxide
691
Dec
598
iron
586
DNA
534
superoxide radical
475
sodium
423
calcium
381
water
380
Clin
371
HPP
342
GSH
331
GSH
331
molybdenum
318
glucose
305
NADPH
282
NADPH
282
phosphate
267
ATP
260
acetate
253
nitrogen
252
NADH
251
ethanol
250
arginine
209
aldehyde
199
potassium
192
NAD
185
cysteine
185
copper
181
EDTA
146
creatinine
146
EDTA
144
NAD
143
DPPH
133
acetaldehyde
126
ADP
125
nicotinamide
124
urea
122
nitrate
118
ADP
109
ADP
109
Xanthine
107
Uric acid
106
salt
102
Cardiol
99
methanol
98
sulfate
98
zinc
94
tyrosine
93
aldehyde
92
CO2
92
DMSO
87
TNF
86
cyanide
82
FAD
80
Phe
79
N-acetylcysteine
73
ethyl acetate
73
tungsten
72
manganese
71
caffeine
69
GSSG
69
PEG
67
AMP
67
glutamate
66
MDA
64
galactose
62
hydroxide
62
pyrimidine
60
pyrimidine
60
Hypoxanthine
56
methionine
55
cGMP
55
chromate
55
prostacyclin
52
ammonium
50
PMA
49
selenium
47
more...