Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.17.3.2 (xanthine oxidase)
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Human Gene/Protein
EVI-5 11.9
xanthine oxidase 11.8
xanthine oxidoreductase 11.7
CYPIIIA4 10.9
xanthine dehydrogenase 10.7
2P domain potassium channel 10.3
aldehyde oxidase 1 10.0
aldehyde oxidase 9.9
IOP2 9.9
nuclear prelamin A recognition factor 9.9
SAPK-interacting protein 1 9.9
CT39 9.9
urate transporter 1 9.8
XDH 9.7
Aldehyde oxidase 1 9.6
GLUT9 9.3
TALK-1 9.0
nucleoside phosphorylase 8.9
Butyrophilin 8.8
butyrophilin 8.8
H2B.2 8.7
gamma-Butyrobetaine hydroxylase 8.7
guanine deaminase 8.6
sulfite oxidase 8.6
alanine-glyoxylate aminotransferase 2 8.6
IMPD 8.4
arylformamidase 8.4
C6orf4 8.4
Neuronal protein 8.4
POLD2 8.4
GTF2H1 8.4
organic anion transporter 1 8.4
TRIM38 8.3
DCTN2 8.3
Guanase 8.3
IOP1 8.3
phosphoribosyl pyrophosphate amidotransferase 8.3
SEPW1 8.2
MT1R 8.2
GB5 8.2
more...
Disease
Chronic clonorchiasis 11.9
Molybdenum deficiency 10.3
Xanthine oxidase deficiency 10.1
Xanthinuria 9.9
Yoshida Sarcoma 9.1
Sulfite oxidase deficiency 8.6
APRT deficiency 8.6
hyperuricemia 8.5
streptoccocal 8.3
gout 8.0
Colonic obstruction 7.9
histiocytic leukemia 7.7
Recurrent herpes labialis 7.6
GPHN 7.6
podagra 7.6
Mammary adenocarcinoma 7.6
tophi 7.6
Gouty arthritis 7.5
Acute gouty arthritis 7.4
PAPA 7.0
uricosuria 7.0
Disuse atrophy 6.8
Molybdenum cofactor deficiency 6.6
renin-dependent hypertension 6.5
CG3 6.4
ADA deficiency 6.4
Exertional rhabdomyolysis 6.3
tumor lysis syndrome 6.2
FBD 6.1
ALS2 5.9
Rotavirus gastroenteritis 5.9
Lesch-Nyhan syndrome 5.8
diabetic cataract 5.7
Harley 5.7
PNP deficiency 5.6
hepatic echinococcosis 5.6
alcoholic cardiomyopathy 5.5
renal ischemia 5.5
VDI 5.5
Oxygen toxicity 5.4
more...
Symptom
Macula 5.0
autodigestion 4.6
throat irritation 4.4
Anoxia 4.4
catarrh 4.3
hyperoxia 4.3
skin damage 4.1
disturbed balance 4.1
athetosis 3.9
No adverse effect 3.6
prostration 3.4
renal colic 3.2
hyperesthesia 2.8
ketonuria 2.8
oliguria 2.6
leg edema 2.5
rigors 2.2
twitching 1.9
functional recovery 1.9
colic 1.8
eds 1.8
muscle rigidity 1.8
respiratory distress 1.6
hypertonia 1.6
dry eye 1.5
tonic-clonic seizure 1.5
exhaustion 1.3
hypocapnia 1.2
hypothermia 1.1
neuralgia 1.1
arthralgia 1.1
cachexia 1.0
angina 1.0
flushing 0.8
skin irritation 0.8
myalgia 0.8
acute stress 0.7
starvation 0.6
acidity 0.6
erythema 0.5
more...
Drug
Dezaguanine 11.9
Amflutizole 11.9
Y-700 11.6
Febuxostat 11.1
Desciclovir 10.3
Fenazox 10.3
Lodoxamide tromethamine 9.7
Pirenoxine 9.6
Guanoxabenz 9.6
Chrysanthemum flower 9.6
Fudosteine 9.3
Troxipide 9.3
Moco 9.0
Succinobucol 8.9
Bifemelane hydrochloride 8.9
Gefarnate 8.7
Angelica dahurica root 8.7
Atractylodes rhizome 8.7
Bupleurum root 8.7
Pinellia tuber 8.6
Scutellaria root 8.5
Nadifloxacin 8.1
Tantum 8.1
Maribavir 8.0
7,8-Dihydroneopterin 7.9
Argininosuccinate 7.8
Rasburicase 7.8
Desferal 7.7
Bendazac 7.6
TMX 7.6
Desferal 7.6
Dipentum 7.6
Pentastarch 7.6
Plaunotol 7.5
Nitecapone 7.4
Sesame oil 7.4
Rasburicase 7.4
Tanespimycin 7.4
Oxyphenbutazone 7.4
Rifalazil 7.3
more...
Enzyme
xanthine oxidase 11.9
xanthine dehydrogenase 11.2
quinaldic acid 4-oxidoreductase 10.9
quinaldic acid 4-oxidoreductase 10.9
aldehyde oxidase 9.9
isoquinoline 1-oxidoreductase 9.9
4-hydroxybenzoyl-CoA reductase 9.6
quinoline 2-oxidoreductase 9.4
melilotate hydroxylase 9.3
pyrimidine deoxyribonucleoside 2'-hydroxylase 9.3
guanase 9.0
sulfite oxidase 8.7
nicotinic acid hydroxylase 8.6
guanosine deaminase 8.6
sulfite oxidase 8.5
histolysain 8.4
uricase 8.3
allantoicase 8.1
thymine 7-hydroxylase 7.9
retinal oxidase 7.8
amidophosphoribosyltransferase 7.6
2-nitropropane dioxygenase 7.5
indole 2,3-dioxygenase 7.5
aldehyde dehydrogenase 7.4
EC 1.3.2.3 7.3
NADPH oxidase 7.2
purine nucleoside phosphorylase 7.2
NADPH oxidase 7.0
allantoinase 6.9
superoxide dismutase 6.9
formylmethanofuran dehydrogenase 6.8
octanol dehydrogenase 6.7
putrescine oxidase 6.7
superoxide reductase 6.6
glucose oxidase 6.5
catalase 6.5
kynurenine formamidase 6.5
DHOdehase 6.5
prostacyclin synthase 6.5
adenosine deaminase 6.5
more...
Compound
1H-pyrrolo[3,2-c]pyridine-4,6(5H,7H)-dione 11.9
Colchizin 11.9
6-(chloromethyl)-9H-purine 11.9
S-Methylisothiourea sulfate 11.9
2-Amino-6-chloropurine 11.9
4-Hydroxypteridine 11.9
Afzelechin 11.9
1,7-dihydropyrano[4,3-b]pyrrole-4,6-dione 11.9
Oxypurinol 11.0
1-chlorophthalazine 10.9
2-naphthyl laurate 10.9
2-hydroxy-6-pentadecylbenzoic acid 10.9
Jacareubin 10.9
N-phenylisonicotinamide 10.9
3,5-dichloro-2-hydroxybenzenesulfonic acid 10.6
C15H10O7 10.3
Urothione 10.3
C15H10O7 10.3
C15H10O7 10.3
C9H13N3O5 10.3
4-chloro-7H-pyrrolo[2,3-d]pyrimidine 10.3
C14H8N4O6 10.3
C15H10O7 10.3
ethyl undecanoate 10.3
2-phenyl-1H-imidazole 10.2
Xanthine 10.1
Pedalitin 9.9
sebacamide 9.9
Luteolin 7-O-glucoside 9.9
Benziodarone 9.9
Cardol 9.9
C8H8O3 9.9
C15H10O7 9.9
Tinoridine 9.9
C20H24O6 9.9
C15H10O7 9.9
HPP 9.8
Purpurogallin 9.8
stearaldehyde 9.6
C15H10O7 9.6
more...