Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.17.1.4 (xanthine dehydrogenase)
 1,236 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
Cell death-inducing DFFA-like effector a 14.7
xanthine dehydrogenase 14.7
xanthine oxidoreductase 14.4
XDH 13.2
molybdenum cofactor sulfurase 13.1
aldehyde oxidase 1 12.8
SSXT 12.7
MOCS1 12.5
MOCS2 12.1
aldehyde oxidase 12.0
Derlin-3 11.7
GZMH 11.7
sulfite oxidase 11.5
CFD1 11.5
HMCS 11.5
Sulfite oxidase 11.1
phosphoribosyl pyrophosphate amidotransferase 11.1
TRIM38 11.1
peroxisomal biogenesis factor 6 11.0
MOCS3 10.8
bone marrow stromal cell antigen 1 10.8
GPH 10.8
HB6 10.7
MOT1 10.5
xanthine oxidase 10.4
butyrophilin 10.4
guanine deaminase 10.4
GPHN 10.3
NOS1 protein 10.3
granzyme H 10.2
BTN2A1 10.1
MPT synthase 10.0
NADPH oxidase 5 9.7
Cytokine-induced apoptosis inhibitor 1 9.7
SDSL 9.7
selenocysteine lyase 9.7
FADH2 9.7
Butyrophilin 9.6
GLUT9 9.6
CEB1 9.5
MUC15 9.4
PAPSS2 9.4
Cytochrome P450 reductase 9.4
TM4SF1 9.3
PRS I 9.3
IscS 9.3
BTN3A1 9.2
urate transporter 1 9.2
acid-sensing ion channel 2 9.2
Neutral sphingomyelinase 9.1
cysteine desulfurase 9.1
adipophilin 9.1
BTN 9.1
UDP-glucose 6-dehydrogenase 8.9
hypoxanthine guanine phosphoribosyltransferase 8.9
NPT1 8.8
ALC 8.8
NOS1 8.8
DFFA 8.7
ALS2 8.7
adenosine monophosphate deaminase 8.7
multidrug resistance-associated protein 4 8.7
sirtuin 6 8.6
NADP+-dependent isocitrate dehydrogenase 8.6
AOX1 8.6
VAV 8.5
organic anion transporter 1 8.4
WS3 8.4
FSP27 8.4
PRY 8.4
GRF1 8.3
NIT2 8.3
claudin 5 8.2
nitric oxide synthase 1 8.2
RST 8.2
amidophosphoribosyltransferase 8.2
PDE5A 8.2
adenylosuccinate synthetase 8.2
ASG 8.1
nar 8.1
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Disease
Xanthine oxidase deficiency 13.4
Xanthinuria 13.2
Molybdenum cofactor deficiency 13.0
purine metabolism disorder 11.8
APRT deficiency 11.1
streptoccocal 11.1
Colonic obstruction 10.7
GPHN 10.4
MKKS 9.3
cystathioninuria 8.8
AO2 8.7
ALS2 8.7
hyperuricemia 8.5
ASG 8.2
RHS 7.8
hypermethioninemia 7.8
uricosuria 7.8
primary amebic meningoencephalitis 7.6
gout 7.4
Intestinal ischemia 7.3
Lowe 7.0
HOPS 6.9
CPL 6.9
LAD2 6.6
Lesch-Nyhan syndrome 6.5
rhinovirus infection 6.5
Copper deficiency 6.3
Severe sepsis 6.2
urolithiasis 6.2
nephrolithiasis 6.1
FDH 5.9
Dupuytren 5.9
Heymann nephritis 5.9
dry eye syndrome 5.8
homocystinuria 5.8
alcoholic pancreatitis 5.8
LMS 5.7
LMS 5.7
nephrosis 5.6
Dupuytren's disease 5.6
HPP 5.5
NCR 5.5
HPP 5.4
hyperphenylalaninemia 5.4
cystinuria 5.4
KNO 5.3
Pulmonary arterial hypertension 5.2
AIC 5.2
Crouzon syndrome 5.2
CVS 5.2
chronic stable angina 5.1
tumor lysis syndrome 5.1
ischemia 5.1
Larsen 5.1
PMS 5.0
Chronic kidney disease (CKD) 5.0
Dandy-Walker malformation 5.0
interstitial nephritis 5.0
renal ischemia 4.9
Mastitis 4.9
CEP 4.9
testicular atrophy 4.9
HPC 4.8
LMS 4.8
maple syrup urine disease 4.7
metabolic disorder 4.7
SMC 4.5
pH increased 4.5
megacolon 4.4
NAME 4.4
renal impairment 4.4
tubular necrosis 4.4
glycogen storage disease 4.3
parasitic disease 4.2
Adenocarcinoma 4.2
enzyme deficiency 4.2
rheumatism 4.2
severe mental retardation 4.2
Mitchell 4.1
MICA 4.1
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Symptom
Spastic 7.2
Anoxia 6.5
autodigestion 6.3
Decreased activity 5.6
hyperoxia 5.1
renal colic 5.0
general problem 4.9
colic 4.6
dry eye 4.3
flushing 3.6
dysuria 3.4
hemiplegia 2.7
starvation 2.6
acute stress 2.5
shortness of breath 2.3
seizures 2.3
hypothermia 2.2
respiratory distress 2.0
anorexia 1.9
arthralgia 1.8
sleepiness 1.0
functional recovery 0.9
vomiting 0.7
angina 0.3
anesthesia 0.2
nausea 0.1
cough 0.1
diarrhea -0.2
abdominal pain -0.3
fatigue -1.0
headache -1.1
pain -1.3
Drug
Moco 12.7
Y-700 12.2
Febuxostat 11.1
Dipentum 10.3
Sodium metabisulfite 9.2
Rasburicase 8.7
Chlorate 8.5
TMX 8.4
FAD 7.9
Indapamide 7.8
Nitric Oxide 7.3
Iodixanol 7.3
all-trans-retinol 7.0
Desferal 6.7
RAL 6.7
Pyridoxal 6.6
Desferal 6.6
NADH 6.4
Doyle 6.0
Trifluoperazine 5.9
Valsartan 5.8
Omeprazole 5.7
AIC 5.6
Rutin 5.3
Adenosine deaminase 5.2
pyridoxal phosphate 4.9
Adenosine triphosphate 4.8
DFP 4.8
niacin 4.8
Reserpine 4.7
Vitamin B 4.4
Arsenic trioxide 4.3
Methylene blue 4.3
MgSO4 4.1
Ethanol 4.0
Vitamin E 4.0
Retinoic acid 3.9
Fructose 3.8
ascorbate 3.7
Albumin 3.4
Imatinib 3.4
Histamine 3.2
Alanine 3.2
Ringer's solution 3.2
Growth hormone 3.1
Vitamin A 3.1
Growth hormone 3.1
caffeine 3.1
ROS 3.0
vitamin E 2.9
Gel 2.8
Fluorescein 2.8
THF 2.7
lactose 2.6
ABC 2.5
nitroglycerin 2.5
Adriamycin 2.5
ICI 2.3
CaCl2 2.0
CaCl2 2.0
CaCl2 2.0
IFN-gamma 1.8
Asn 1.1
lysine 1.1
CSF 0.7
Leaf 0.2
Cardiovasc -0.1
Dial -0.3
Monit -0.4
Dermatol -2.3
Enzyme
6-hydroxynicotinate reductase 14.7
xanthine dehydrogenase 14.7
glucose phosphomutase 14.7
methylitaconate isomerase 14.7
quinaldic acid 4-oxidoreductase 13.7
quinaldic acid 4-oxidoreductase 13.7
2-furoyl-CoA dehydrogenase 13.7
pyridoxal oxidase 13.3
thiol:disulphide oxidoreductase 13.1
carbon-monoxide dehydrogenase 13.1
nicotinic acid hydroxylase 13.0
aldehyde oxidase 12.0
allantoin racemase 11.8
sulfite oxidase 11.5
allantoinase 11.4
allantoicase 11.4
sulfite oxidase 11.4
guanosine deaminase 11.3
quinoline 2-oxidoreductase 11.2
xanthine oxidase 11.2
2-methyleneglutarate mutase 11.1
adenine deaminase 10.6
retinal oxidase 10.6
ureidoglycolate lyase 10.3
allantoate amidohydrolase 10.0
acetylene hydratase 10.0
uricase 9.9
L-asparagine synthetase 9.8
amidophosphoribosyltransferase 9.7
guanase 9.6
PRPP synthetase 9.5
selenocysteine lyase 9.5
nicotine oxidase 9.5
AO1 9.5
octanol dehydrogenase 9.5
aldehyde dehydrogenase 9.4
IscS 9.0
EC 1.7.7.1 9.0
glycine reductase 9.0
DAP II 8.9
nitrate reductase 8.8
nitrate reductase 8.8
nitrate reductase 8.8
nitrate reductase 8.8
nitrate reductase 8.8
nitrate reductase 8.7
NAD+ oxidoreductase 8.5
xanthine phosphoribosyltransferase 8.5
methylenetetrahydrofolate dehydrogenase 8.4
AMP deaminase 8.4
nitrite reductase 8.4
nitrite reductase 8.4
nitrite reductase 8.3
NADPH:quinone oxidoreductase 8.3
nucleoside hydrolase 8.1
triose-phosphate isomerase 8.1
adenine phosphoribosyltransferase 8.0
ketohexokinase 8.0
adenylosuccinate synthetase 7.9
phosphoglycerate dehydrogenase 7.9
purine nucleoside phosphorylase 7.9
CO dehydrogenase 7.8
ribokinase 7.8
GMP synthetase 7.4
formate dehydrogenase 7.4
formate dehydrogenase 7.3
formate dehydrogenase 7.3
NAO 7.2
NADH-cytochrome b5 reductase 7.2
sepiapterin reductase 7.1
adenylosuccinate lyase 7.1
NQO2 7.1
glutamate synthase 7.1
glutamic dehydrogenase 6.8
IMP dehydrogenase 6.8
asparagine synthetase 6.7
glutamate synthase 6.7
CPL 6.6
glutamate synthase 6.6
nitrogenase 6.5
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Compound
2-naphthyl laurate 13.7
Urothione 13.1
Molybdenum cofactor 12.2
2-phenyl-1H-imidazole 11.3
allantoate 10.8
2-furaldehyde semicarbazone 10.7
Xanthine 10.5
Oxypurinol 10.4
2-amino-2-(hydroxymethyl)-1,3-propanediol 10.3
2-amino-2-(hydroxymethyl)-1,3-propanediol 10.3
S-sulfocysteine 10.3
2-amino-2-(hydroxymethyl)-1,3-propanediol 10.3
6-hydroxynicotinic acid 10.2
6-hydroxynicotinic acid 10.2
ureidoglycolate 9.7
6-pyruvoyltetrahydropterin 9.7
Sepiapterin 9.6
Benzbromarone 9.5
Benzamidine 9.5
HPP 9.4
Allantoin 9.4
Allantoin 9.4
molybdenum 9.0
Uric acid 9.0
Hypoxanthine 8.9
quinoline-2-carboxylic acid 8.9
C2H4O2 8.8
Chlorate 8.8
1-naphthyl acetate 8.6
Pterin 8.6
Maneb 8.5
Chlorate 8.3
DTE 8.1
Esculin 8.0
Ethionine 7.9
Nitrite 7.9
Procarbazine 7.9
FAD 7.8
Stigmasterol 7.7
Nitrite 7.6
N-methylnicotinamide 7.6
Purine 7.6
4-NQO 7.5
2-furoic acid 7.4
Apocynin 7.4
2-furoic acid 7.3
Acteoside 7.3
Furazolidone 7.3
Sodium bisulfite 7.3
Hesperetin 7.1
pteridine 7.1
cyanamide 7.0
MoO3 7.0
Benznidazole 7.0
Benznidazole 7.0
Benznidazole 7.0
DEG 7.0
tungsten 7.0
Adenine 6.9
Dimethylhydrazine 6.9
CPL 6.9
PRPP 6.9
Mangiferin 6.8
Desferal 6.7
2-furoic acid 6.6
4-Hydroxynonenal 6.6
BHC 6.6
Pyridoxal 6.6
NAD 6.6
Tocopherols 6.5
Carcinogen 6.5
NAD 6.4
Na2S 6.4
Probenecid 6.4
NADH 6.4
2,6-dichlorophenol 6.3
FMNH 6.3
Kynurenic acid 6.1
CCC 6.1
NMA 6.1
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