Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.17.1.4 (xanthine dehydrogenase)
 1,236 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
xanthine dehydrogenase 848
xanthine oxidase 459
xanthine oxidoreductase 435
aldehyde oxidase 126
Sep 91
Mol 81
NADH 73
NAD 67
XDH 65
superoxide dismutase 62
catalase 57
FAD 50
sulfite oxidase 49
nitric oxide synthase 38
NAD+ 37
ATP 37
reductase 34
lactate dehydrogenase 27
glutathione peroxidase 24
AMP 23
Pseudomonas 21
NADPH 21
oxidoreductase 18
myeloperoxidase 18
GSH 17
insulin 16
polypeptide 15
cytokine 14
gut 13
flavoprotein 13
purine nucleoside phosphorylase 13
hemoglobin 13
cytochrome P450 12
microsomal 12
EPR 11
aspartate aminotransferase 11
Gen 11
adenosine deaminase 11
butyrophilin 11
IL-6 11
lipopolysaccharide 10
TNF 10
myoglobin 10
GTP 10
neuronal nitric oxide synthase 10
collagen 10
alkaline phosphatase 10
albumin 10
SOD 10
aldehyde dehydrogenase 10
cytochrome 9
glutamine synthetase 9
5'-nucleotidase 9
MOCS1 9
peroxidase 8
SDS 8
tumor necrosis factor 8
A-I 8
alcohol dehydrogenase 8
AOX1 7
IscS 7
aldehyde oxidase 1 7
endoplasmic reticulum 7
Chlamydomonas 7
IMP 7
molybdenum cofactor sulfurase 7
membrane-bound 7
FADH2 7
glucose-6-phosphate dehydrogenase 7
soluble guanylyl cyclase 7
heme oxygenase-1 7
casein 7
NOS1 7
cyclooxygenase 7
esterase 7
Sulfite oxidase 7
guanine deaminase 7
cysteine desulfurase 6
inducible nitric oxide synthase 6
ROS 6
more...
Disease
ischemia 118
hyperuricemia 54
gout 35
hypertension 29
cancer 25
diabetes 22
renal disease 21
tumor 19
GSH 17
heart failure 15
obesity 15
cold 14
myocardial infarction 14
Molybdenum cofactor deficiency 12
metabolic syndrome 11
atherosclerosis 11
myocardial ischemia 11
NAME 11
urolithiasis 11
renal failure 10
Xanthinuria 10
cardiovascular disease 9
SDS 8
breast cancer 8
APRT deficiency 7
nephrolithiasis 7
type 2 diabetes 7
renal impairment 5
mental retardation 5
renal insufficiency 5
tumorigenesis 5
hyperlipidemia 5
proteinuria 5
carcinoma 5
cerebral ischemia 5
metabolic disorder 5
depression 5
dyslipidemia 5
mental retardation 5
carcinogenesis 5
leukemia 4
amyotrophic lateral sclerosis 4
lung cancer 4
acute pancreatitis 4
arthritis 4
tumor growth 4
cornea 4
hyperglycemia 4
developmental delay 4
Xanthine oxidase deficiency 3
dehydration 3
Blocking 3
interstitial nephritis 3
rare disease 3
renal ischemia 3
pulmonary hypertension 3
vascular disease 3
Alzheimer's disease 3
Lesch-Nyhan syndrome 3
genetic disorder 3
fits 3
fatty liver 3
uterus 3
SEM 3
nephrosis 3
hypercholesterolemia 3
hepatocellular carcinoma 3
brain atrophy 3
sepsis 3
acute renal failure 3
asthma 3
sepsis 3
cervical intraepithelial neoplasia 3
sickle cell disease 2
chronic obstructive pulmonary disease 2
Klebsiella 2
Chagas 2
Wright 2
preeclampsia 2
prostate cancer 2
more...
Symptom
seizures 15
hyperoxia 7
starvation 6
anesthesia 5
pain 4
colic 3
flushing 3
respiratory distress 3
hypothermia 3
anorexia 2
Anoxia 2
dry eye 2
vomiting 2
diarrhea 2
fatigue 1
nausea 1
Decreased activity 1
general problem 1
arthralgia 1
abdominal pain 1
cough 1
sleepiness 1
Spastic 1
shortness of breath 1
renal colic 1
hemiplegia 1
angina 1
dysuria 1
functional recovery 1
headache 1
autodigestion 1
acute stress 1
Drug
NADH 70
FAD 50
Nitric Oxide 16
Febuxostat 12
ascorbate 12
Moco 8
Cardiovasc 7
caffeine 7
Ethanol 6
ROS 6
lysine 5
vitamin E 5
lactose 4
Gel 4
IFN-gamma 4
niacin 4
Rasburicase 4
pyridoxal phosphate 3
Indapamide 3
Chlorate 2
ABC 2
Y-700 2
THF 2
Vitamin E 2
Histamine 2
Retinoic acid 2
all-trans-retinol 2
CSF 2
Omeprazole 2
Albumin 2
Dermatol 2
nitroglycerin 2
Growth hormone 1
Methylene blue 1
Desferal 1
Arsenic trioxide 1
RAL 1
Doyle 1
TMX 1
CaCl2 1
Leaf 1
CaCl2 1
AIC 1
DFP 1
Asn 1
Ringer's solution 1
Desferal 1
Pyridoxal 1
Vitamin A 1
CaCl2 1
Alanine 1
Growth hormone 1
Reserpine 1
Adriamycin 1
Fructose 1
Valsartan 1
Monit 1
ICI 1
Rutin 1
MgSO4 1
Adenosine triphosphate 1
Sodium metabisulfite 1
Adenosine deaminase 1
Fluorescein 1
Iodixanol 1
Imatinib 1
Dipentum 1
Vitamin B 1
Dial 1
Trifluoperazine 1
Enzyme
xanthine dehydrogenase 1236
xanthine oxidase 750
aldehyde dehydrogenase 135
aldehyde oxidase 121
superoxide dismutase 67
nitrate reductase 65
nitrate reductase 64
nitrate reductase 64
nitrate reductase 64
nitrate reductase 63
nitrate reductase 63
catalase 58
sulfite oxidase 49
sulfite oxidase 49
uricase 44
lactate dehydrogenase 28
NADPH oxidase 27
glutathione peroxidase 25
peroxidase 24
nitrite reductase 24
nitrite reductase 24
nitrite reductase 24
NADPH oxidase 22
allantoinase 13
nitrogenase 13
NO synthase 13
adenosine deaminase 13
purine nucleoside phosphorylase 13
aspartate aminotransferase 13
adenosine deaminase 11
glutamine synthetase 10
aldehyde dehydrogenase 10
alkaline phosphatase 10
aldehyde dehydrogenase 10
aldehyde dehydrogenase 10
aldehyde dehydrogenase 10
NOS 9
AMP deaminase 9
creatine kinase 9
IscS 9
5'-nucleotidase 9
alanine aminotransferase 8
NQO1 8
alcohol dehydrogenase 8
arginase 8
trypsin 7
glucose-6-phosphate dehydrogenase 7
mitogen-activated protein kinase 7
glutamate dehydrogenase 7
adenine phosphoribosyltransferase 7
diaphorase 7
glutamate dehydrogenase 7
glutamate dehydrogenase 7
guanase 7
formate dehydrogenase 7
PRPP synthetase 7
dihydrofolate reductase 6
nicotinic acid hydroxylase 6
ATPase 6
formate dehydrogenase 6
malate dehydrogenase 6
adenine deaminase 6
allantoicase 6
succinate dehydrogenase 6
formate dehydrogenase 6
elastase 6
lipoxygenase 5
hypoxanthine-guanine phosphoribosyltransferase 5
deaminase 5
pyridoxal oxidase 5
urease 5
urease 5
protein kinase 5
phospholipase A2 4
glutathione S-transferase 4
IMP dehydrogenase 4
luciferase 4
glutamate synthase 4
amidophosphoribosyltransferase 4
glutathione reductase 4
more...
Compound
oxygen 295
molybdenum 195
NAD 100
nitric oxide 98
nitrogen 95
Dec 88
iron 88
nitrate 73
NADH 70
DNA 68
NAD 67
hydrogen 54
FAD 50
sodium 43
Clin 42
aldehyde 41
phosphate 39
ATP 37
HPP 37
tungsten 35
calcium 35
cysteine 32
ethanol 30
water 30
Uric acid 29
H2O2 28
arginine 27
urea 26
aldehyde 26
Nitrite 23
Nitrite 22
glucose 21
ammonia 21
NADPH 21
NADPH 21
salt 20
Xanthine 20
acetaldehyde 18
copper 18
AMP 18
potassium 18
cyanide 17
sulfate 17
GSH 17
GSH 17
creatinine 17
glutamate 16
nicotinamide 16
ammonium 16
Cardiol 15
Molybdenum cofactor 15
acetate 14
selenium 14
CO2 13
cGMP 13
methionine 13
SDS 11
superoxide radical 11
methanol 10
Gly 10
zinc 10
TNF 10
GTP 10
alanine 9
pyridine 9
pyrimidine 8
glutamine 8
ADP 8
serine 8
alcohol dehydrogenase 8
tyrosine 8
pyrimidine 8
NH2 8
Adenine 7
Purine 7
Nitrate 7
caffeine 7
Hypoxanthine 7
lysine 7
Adenine 7
more...