Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.17.1.4 (xanthine dehydrogenase)
 1,236 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
xanthine dehydrogenase 848
xanthine oxidase 459
xanthine oxidoreductase 435
aldehyde oxidase 126
Sep 91
Mol 81
NADH 73
NAD 67
XDH 65
superoxide dismutase 62
catalase 57
FAD 50
sulfite oxidase 49
nitric oxide synthase 38
ATP 37
NAD+ 37
reductase 34
lactate dehydrogenase 27
glutathione peroxidase 24
AMP 23
Pseudomonas 21
NADPH 21
myeloperoxidase 18
oxidoreductase 18
GSH 17
insulin 16
polypeptide 15
cytokine 14
hemoglobin 13
gut 13
flavoprotein 13
purine nucleoside phosphorylase 13
microsomal 12
cytochrome P450 12
adenosine deaminase 11
EPR 11
IL-6 11
butyrophilin 11
aspartate aminotransferase 11
Gen 11
collagen 10
albumin 10
myoglobin 10
lipopolysaccharide 10
neuronal nitric oxide synthase 10
alkaline phosphatase 10
SOD 10
TNF 10
GTP 10
aldehyde dehydrogenase 10
cytochrome 9
glutamine synthetase 9
MOCS1 9
5'-nucleotidase 9
tumor necrosis factor 8
A-I 8
peroxidase 8
alcohol dehydrogenase 8
SDS 8
casein 7
Chlamydomonas 7
glucose-6-phosphate dehydrogenase 7
membrane-bound 7
Sulfite oxidase 7
FADH2 7
guanine deaminase 7
soluble guanylyl cyclase 7
cyclooxygenase 7
AOX1 7
esterase 7
aldehyde oxidase 1 7
NOS1 7
IscS 7
heme oxygenase-1 7
IMP 7
molybdenum cofactor sulfurase 7
endoplasmic reticulum 7
ROS 6
apoE 6
inducible nitric oxide synthase 6
CO2 6
ADP 6
MOCS2 6
glutamate dehydrogenase 6
LPS 6
malate dehydrogenase 6
creatine kinase 6
alanine aminotransferase 6
cysteine desulfurase 6
ALC 6
adipophilin 5
CPR 5
gephyrin 5
tyrosine kinase 5
non-functional 5
p38 5
hypoxanthine-guanine phosphoribosyltransferase 5
AMP deaminase 5
lipoxygenase 5
vascular endothelium 5
all-trans 5
calmodulin 5
xenobiotic 4
aconitase 4
diaphorase 4
RST 4
prolactin 4
phospholipase A2 4
NADP 4
lactoferrin 4
ATPase 4
cytochrome c 4
Met 4
peroxisome proliferator-activated receptor 4
IFN-gamma 4
A. nidulans 4
dimeric 4
ferredoxin 4
D-amino acid oxidase 4
interferon-alpha 4
tumor necrosis factor alpha 4
interferon 4
Bot 4
D. melanogaster 4
Catalase 4
NMDA receptor 4
acid phosphatase 4
interferon-gamma 4
dihydrofolate reductase 4
glutaredoxin 4
protease inhibitor 4
serine protease inhibitor 4
ABC transporter 3
lysozyme 3
AST 3
EC1 3
ornithine decarboxylase 3
TGA 3
CGA 3
Pol 3
AKT 3
eNOS 3
glutathione reductase 3
chemokine 3
phosphodiesterase 3
leptin 3
6-phosphogluconate dehydrogenase 3
serum albumin 3
trypsin inhibitor 3
glutathione S-transferase 3
cytochrome b 3
thioredoxin 3
MOT1 3
DT-diaphorase 3
perilipin 3
alternatively spliced 3
JNK 3
renin 3
epididymal 3
rat) 3
more...
Disease
ischemia 118
hyperuricemia 54
gout 35
hypertension 29
cancer 25
diabetes 22
renal disease 21
tumor 19
GSH 17
heart failure 15
obesity 15
myocardial infarction 14
cold 14
Molybdenum cofactor deficiency 12
NAME 11
urolithiasis 11
atherosclerosis 11
metabolic syndrome 11
myocardial ischemia 11
Xanthinuria 10
renal failure 10
cardiovascular disease 9
SDS 8
breast cancer 8
APRT deficiency 7
nephrolithiasis 7
type 2 diabetes 7
metabolic disorder 5
dyslipidemia 5
mental retardation 5
carcinoma 5
tumorigenesis 5
renal insufficiency 5
depression 5
renal impairment 5
proteinuria 5
mental retardation 5
cerebral ischemia 5
hyperlipidemia 5
carcinogenesis 5
tumor growth 4
acute pancreatitis 4
leukemia 4
arthritis 4
developmental delay 4
lung cancer 4
cornea 4
hyperglycemia 4
amyotrophic lateral sclerosis 4
SEM 3
uterus 3
dehydration 3
interstitial nephritis 3
Alzheimer's disease 3
vascular disease 3
pulmonary hypertension 3
cervical intraepithelial neoplasia 3
sepsis 3
rare disease 3
Lesch-Nyhan syndrome 3
fits 3
fatty liver 3
hepatocellular carcinoma 3
asthma 3
nephrosis 3
sepsis 3
brain atrophy 3
hypercholesterolemia 3
acute renal failure 3
Xanthine oxidase deficiency 3
Blocking 3
genetic disorder 3
renal ischemia 3
Pulmonary arterial hypertension 2
chronic obstructive pulmonary disease 2
Chagas 2
prostate cancer 2
membranous nephropathy 2
iron deficiency 2
parasitic disease 2
adult respiratory distress syndrome 2
neuropathy 2
lymphoma 2
ALS2 2
Lowe 2
pancreatitis 2
neuroblastoma 2
adenocarcinoma 2
rheumatism 2
Intestinal ischemia 2
cirrhosis 2
essential hypertension 2
arteriosclerosis 2
emphysema 2
pulmonary edema 2
necrotizing enterocolitis 2
encephalopathy 2
glomerulosclerosis 2
stroke 2
osteoarthritis 2
heart disease 2
congestive heart failure 2
pH increased 2
chronic renal failure 2
Chronic kidney disease (CKD) 2
colitis 2
sickle cell disease 2
homocystinuria 2
acute myocardial infarction 2
Klebsiella 2
Wright 2
anemia 2
preeclampsia 2
Dupuytren 2
hyperlipoproteinemia 1
adenocarcinoma of the lung 1
megacolon 1
inflammatory bowel disease 1
erectile dysfunction 1
LMS 1
glaucoma 1
influenza 1
melanoma 1
solid tumor 1
coronary occlusion 1
acute cholecystitis 1
GPHN 1
neutropenia 1
tuberculosis 1
vagina 1
coronary artery disease 1
Crohn's disease 1
glioma 1
Pineal 1
glomerulonephritis 1
periodontitis 1
Poland 1
Adenocarcinoma 1
mole 1
polycystic ovary syndrome 1
celiac disease 1
bacterial meningitis 1
HOPS 1
suicide 1
dry eye syndrome 1
glycogen storage disease 1
hyperphenylalaninemia 1
FDH 1
West 1
mole 1
meningoencephalitis 1
enzyme deficiency 1
testicular atrophy 1
duodenal ulcer 1
HPP 1
plaque 1
learning disability 1
Fanconi syndrome 1
aggressiveness 1
blast crisis 1
more...
Symptom
seizures 15
hyperoxia 7
starvation 6
anesthesia 5
pain 4
colic 3
flushing 3
respiratory distress 3
hypothermia 3
anorexia 2
Anoxia 2
dry eye 2
vomiting 2
diarrhea 2
fatigue 1
nausea 1
Decreased activity 1
general problem 1
arthralgia 1
abdominal pain 1
cough 1
sleepiness 1
Spastic 1
shortness of breath 1
renal colic 1
hemiplegia 1
angina 1
dysuria 1
functional recovery 1
headache 1
autodigestion 1
acute stress 1
Drug
NADH 70
FAD 50
Nitric Oxide 16
Febuxostat 12
ascorbate 12
Moco 8
Cardiovasc 7
caffeine 7
Ethanol 6
ROS 6
lysine 5
vitamin E 5
lactose 4
Gel 4
IFN-gamma 4
niacin 4
Rasburicase 4
pyridoxal phosphate 3
Indapamide 3
Chlorate 2
ABC 2
Y-700 2
THF 2
Vitamin E 2
Histamine 2
Retinoic acid 2
all-trans-retinol 2
CSF 2
Omeprazole 2
Albumin 2
Dermatol 2
nitroglycerin 2
Growth hormone 1
Methylene blue 1
Desferal 1
Arsenic trioxide 1
RAL 1
Doyle 1
TMX 1
CaCl2 1
Leaf 1
CaCl2 1
AIC 1
DFP 1
Asn 1
Ringer's solution 1
Desferal 1
Pyridoxal 1
Vitamin A 1
CaCl2 1
Alanine 1
Growth hormone 1
Reserpine 1
Adriamycin 1
Fructose 1
Valsartan 1
Monit 1
ICI 1
Rutin 1
MgSO4 1
Adenosine triphosphate 1
Sodium metabisulfite 1
Adenosine deaminase 1
Fluorescein 1
Iodixanol 1
Imatinib 1
Dipentum 1
Vitamin B 1
Dial 1
Trifluoperazine 1
Enzyme
xanthine dehydrogenase 1236
xanthine oxidase 750
aldehyde dehydrogenase 135
aldehyde oxidase 121
superoxide dismutase 67
nitrate reductase 65
nitrate reductase 64
nitrate reductase 64
nitrate reductase 64
nitrate reductase 63
nitrate reductase 63
catalase 58
sulfite oxidase 49
sulfite oxidase 49
uricase 44
lactate dehydrogenase 28
NADPH oxidase 27
glutathione peroxidase 25
peroxidase 24
nitrite reductase 24
nitrite reductase 24
nitrite reductase 24
NADPH oxidase 22
adenosine deaminase 13
aspartate aminotransferase 13
purine nucleoside phosphorylase 13
allantoinase 13
nitrogenase 13
NO synthase 13
adenosine deaminase 11
alkaline phosphatase 10
aldehyde dehydrogenase 10
aldehyde dehydrogenase 10
aldehyde dehydrogenase 10
aldehyde dehydrogenase 10
glutamine synthetase 10
IscS 9
NOS 9
creatine kinase 9
AMP deaminase 9
5'-nucleotidase 9
NQO1 8
alcohol dehydrogenase 8
arginase 8
alanine aminotransferase 8
glutamate dehydrogenase 7
glutamate dehydrogenase 7
adenine phosphoribosyltransferase 7
formate dehydrogenase 7
mitogen-activated protein kinase 7
guanase 7
trypsin 7
glucose-6-phosphate dehydrogenase 7
glutamate dehydrogenase 7
diaphorase 7
PRPP synthetase 7
ATPase 6
dihydrofolate reductase 6
formate dehydrogenase 6
formate dehydrogenase 6
malate dehydrogenase 6
nicotinic acid hydroxylase 6
succinate dehydrogenase 6
allantoicase 6
adenine deaminase 6
elastase 6
lipoxygenase 5
hypoxanthine-guanine phosphoribosyltransferase 5
deaminase 5
pyridoxal oxidase 5
urease 5
urease 5
protein kinase 5
IMP dehydrogenase 4
glutathione S-transferase 4
phospholipase A2 4
glutathione reductase 4
diaphorase 4
aconitase 4
acid phosphatase 4
NADPH-diaphorase 4
amidophosphoribosyltransferase 4
luciferase 4
glutamate synthase 4
glutamate synthase 3
caspase-3 3
NAD+ oxidoreductase 3
nucleoside hydrolase 3
phosphoglycerate dehydrogenase 3
carbonic anhydrase 3
glycerol-3-phosphate dehydrogenase 3
ornithine decarboxylase 3
phosphodiesterase 3
6-phosphogluconate dehydrogenase 3
6-phosphogluconate dehydrogenase 3
glycerol-3-phosphate dehydrogenase 3
renin 3
CPR 3
lysozyme 3
NADH-cytochrome b5 reductase 3
adenosine kinase 3
glutamate synthase 3
protein kinase C 2
caspase-1 2
hydrogenase 2
thrombin 2
DAP II 2
reverse transcriptase 2
AMP-activated protein kinase 2
methylenetetrahydrofolate dehydrogenase 2
acetylcholinesterase 2
subtilisin 2
ricin 2
serine hydroxymethyltransferase 2
RNase 2
triose-phosphate isomerase 2
dihydropyrimidine dehydrogenase 2
ceruloplasmin 2
glucose-6-phosphatase 2
tyrosine aminotransferase 2
aldolase 2
heme oxygenase 2
dihydropyrimidine dehydrogenase 2
adenylosuccinate synthetase 2
CO dehydrogenase 2
cathepsin G 2
isocitrate dehydrogenase 2
asparagine synthetase 2
isocitrate dehydrogenase 2
GTP cyclohydrolase I 2
focal adhesion kinase 2
hydrogenase 2
neutrophil elastase 1
glutamic dehydrogenase 1
L-asparagine synthetase 1
papain 1
aldose reductase 1
CaMKII 1
ATP sulfurylase 1
tryptophan 2,3-dioxygenase 1
UDP-glucose dehydrogenase 1
retinal oxidase 1
monoamine oxidase 1
MEKK1 1
triphosphatase 1
RNase 1
ADH 1
AMPK 1
asparaginase 1
adenylosuccinate lyase 1
lactate oxidase 1
ureidoglycolate lyase 1
nucleotide pyrophosphatase 1
chymotrypsin 1
firefly luciferase 1
chitinase 1
selenocysteine lyase 1
MDP 1
polyamine oxidase 1
NQO2 1
more...
Compound
oxygen 295
molybdenum 195
NAD 100
nitric oxide 98
nitrogen 95
iron 88
Dec 88
nitrate 73
NADH 70
DNA 68
NAD 67
hydrogen 54
FAD 50
sodium 43
Clin 42
aldehyde 41
phosphate 39
ATP 37
HPP 37
calcium 35
tungsten 35
cysteine 32
water 30
ethanol 30
Uric acid 29
H2O2 28
arginine 27
urea 26
aldehyde 26
Nitrite 23
Nitrite 22
glucose 21
ammonia 21
NADPH 21
NADPH 21
Xanthine 20
salt 20
copper 18
potassium 18
acetaldehyde 18
AMP 18
creatinine 17
sulfate 17
GSH 17
GSH 17
cyanide 17
glutamate 16
nicotinamide 16
ammonium 16
Cardiol 15
Molybdenum cofactor 15
selenium 14
acetate 14
cGMP 13
CO2 13
methionine 13
superoxide radical 11
SDS 11
zinc 10
GTP 10
TNF 10
methanol 10
Gly 10
pyridine 9
alanine 9
tyrosine 8
ADP 8
pyrimidine 8
glutamine 8
serine 8
pyrimidine 8
alcohol dehydrogenase 8
NH2 8
Adenine 7
caffeine 7
Nitrate 7
IMP 7
lysine 7
Hypoxanthine 7
Adenine 7
Purine 7
NADP 6
ADP 6
GSSG 6
Phe 6
retinoic acid 6
allantoate 6
ADP 6
retinol 6
tryptophan 5
tryptophan 5
tryptophan 5
tryptophan 5
S-sulfocysteine 5
nicotinic acid 5
phosphorus 5
CCC 5
DHA 4
GMP 4
DHA 4
threonine 4
cobalt 4
leucine 4
hydroxide 4
cyanamide 4
NMDA 4
DMSO 4
DHA 4
asparagine 4
MDA 4
pteridine 4
galactose 4
NO3 4
phenazine 4
Hearts 4
Oxypurinol 4
Methylene blue 4
benzaldehyde 3
HCl 3
adenylate 3
benzaldehyde 3
Quercetin 3
benzaldehyde 3
benzaldehyde 3
benzaldehyde 3
benzaldehyde 3
benzaldehyde 3
acrylamide 3
thiourea 3
nicotinic acid 3
benzaldehyde 3
EDTA 3
benzaldehyde 3
benzaldehyde 3
benzaldehyde 3
iodine 3
benzaldehyde 3
quinoline 3
acetic acid 3
Phytol 3
benzaldehyde 3
Allantoin 3
benzaldehyde 3
benzaldehyde 3
Allantoin 3
benzaldehyde 3
EDTA 3
benzaldehyde 3
ABA 3
benzaldehyde 3
nicotinic acid 3
benzaldehyde 3
acetone 3
benzaldehyde 3
benzaldehyde 3
benzaldehyde 3
benzaldehyde 3
diacetate 3
nicotinic acid 3
benzaldehyde 3
more...