Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.16.3.1 (ceruloplasmin)
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Human Gene/Protein
schwannomin-interacting protein 1 12.6
DKFZp686P15220 12.6
ATPase Cu++ transporting beta polypeptide 12.6
ferroxidase 12.6
complement component 4B preproprotein 12.6
ceruloplasmin 12.6
transmembrane protein 199 12.6
Ferroxidase 12.6
ceruloplasmin mRNA 12.5
Ceruloplasmin 12.1
ceruloplasmin (ferroxidase) 11.9
hephaestin 11.9
Hephaestin 11.7
cerebral endothelial cell adhesion molecule 11.6
ATPase type 13A2 11.6
angiopoietin-related protein 2 11.6
Clotting factor VIII 11.6
inter-alpha-trypsin inhibitor heavy chain H2 11.0
poliovirus receptor-related 3 11.0
AP1B1 11.0
rab10 11.0
copper transport protein 10.9
ATPase 7B 10.8
ferritin L-chain 10.7
HEPHL1 10.6
hemochromatosis type 2 10.6
GGT3 10.3
GPX3 protein 10.3
latrophilin 2 10.3
hyaluronan binding protein 2 10.0
Copper chaperone for superoxide dismutase 10.0
CPX1 10.0
ATP7B 10.0
CP protein 10.0
ATP7A protein 9.9
B-cell CLL/lymphoma 3 9.8
PC43 9.8
Pantothenate kinase 2 9.8
ATP7B protein 9.8
COX19 9.8
LALP1 9.6
CO9 9.6
ferroportin 1 9.5
Wilson disease 9.5
C2orf37 9.4
FOX1 9.4
H63 9.4
ferroportin1 9.3
microtubule-actin crosslinking factor 1 9.3
C17orf32 9.3
apolipoprotein F 9.3
mitochondrial ferritin 9.2
ATOX1 9.2
ENPP3 9.2
haptoglobin 9.1
ribosomal protein L13a 9.1
ATP7A 9.0
LOT1 9.0
CP25 8.9
MURR1 8.8
Forkhead box protein L2 8.8
phosphoglucomutase 2 8.8
galectin 3 binding protein 8.8
Pregnancy zone protein 8.8
antioxidant protein 1 8.8
STR3 8.8
CST4 8.8
stoned B 8.8
duodenal cytochrome b 8.8
hemopexin 8.7
DMT1 8.7
BATF2 8.7
ferritin light polypeptide 8.7
B3GALNT2 8.7
alpha-2-macroglobulin 8.7
transferin 8.6
CNDP2 8.6
COMMD1 8.5
PCOLCE 8.5
APOC4 8.5
more...
Disease
infected skin cyst 12.6
Ceruloplasmin deficiency 12.6
infected skin cyst 12.6
Ehlers-Danlos syndrome type IX 12.0
Fleisher ring 11.6
iron loading anemia 11.6
SMAX3 11.6
disorders of copper metabolism 11.0
hypercupremia 10.7
Copper deficiency 10.2
reflex disorder 10.0
nutmeg liver 9.8
Psoroptic mange 9.8
POF3 9.8
Wilson's disease 9.7
digestive neoplasm 9.6
trichoptilosis 9.6
Idiopathic thrombocytopenia 9.6
HFE3 9.4
Coombs negative hemolytic anemia 9.3
Menkes 9.2
DEFECT 9.2
Columnaris disease 9.1
Trichorrhexis nodosa 9.0
Pili torti 8.9
rheumatic endocarditis 8.8
Abdominal lymphadenopathy 8.5
peripheral retinal degeneration 8.5
pseudocroup 8.4
idiopathic proctocolitis 8.3
disorders of iron metabolism 8.0
Type V hyperlipoproteinemia 7.9
DMT1 7.9
Hallervorden-Spatz disease 7.7
tyrosinosis 7.4
Subacute combined degeneration 7.4
Witts 7.2
CPL 7.2
microcytic anemia 7.0
OHS 7.0
lipoprotein disorder 6.9
hypochromic anemia 6.8
adaptation reaction 6.8
RCA1 6.7
iron overload 6.6
congenital anemia 6.6
Venous hypertension 6.6
Rotavirus gastroenteritis 6.6
HFE2 6.5
recurrent colon cancer 6.5
aminoaciduria 6.5
extrapyramidal disorder 6.4
intestinal helminthiasis 6.4
Crescentic glomerulonephritis 6.4
circulatory hypoxia 6.4
Distal renal tubular acidosis 6.4
sideroblastic anemia 6.3
basal ganglia disease 6.3
IgM nephropathy 6.3
Aeromonas hydrophila infection 6.3
megalocytosis 6.2
neurobehavioral problems 6.2
Salla disease 6.2
BFR 6.0
AOS 6.0
hemochromatosis 6.0
ancylostomiasis 5.9
hereditary hemochromatosis 5.9
MERRF 5.9
AIN 5.9
iron deficiency 5.8
Angiodysplasia 5.8
normocytic anemia 5.8
choreoathetosis 5.7
grand mal epilepsy 5.7
Acute liver failure 5.7
Eales' disease 5.6
Acute gastroenteritis 5.6
hepatosis 5.5
hematological abnormality 5.5
more...
Symptom
Kayser-Fleischer ring 11.3
disturbed speech 8.6
Climacteric symptoms 7.7
Lasegue's sign 7.5
asterixis 6.9
athetosis 6.6
Behavioral symptoms 6.3
ataxic gait 5.5
dysarthria 5.4
intention tremor 5.2
pedal edema 4.9
cerebellar ataxia 4.7
clumsiness 4.5
dystonia 4.4
urethral discharge 4.4
No adverse effect 4.3
meningism 4.2
emaciation 4.2
hypoproteinemia 4.1
bradykinesia 4.0
tremor 4.0
renal colic 4.0
chorea 3.9
loss of balance 3.8
neurological disability 3.8
myoclonus 3.7
hepatomegaly 3.7
blepharospasm 3.6
hypotonia 3.6
swollen joints 3.6
muscle rigidity 3.5
personality change 3.5
excessive sweating 3.4
Gastrointestinal symptoms 3.4
HSA 3.4
colic 3.3
drooling 3.2
forgetfulness 3.2
right upper quadrant pain 3.2
partial seizure 3.2
ataxia 3.2
hyperoxia 3.1
torticollis 3.0
menopausal symptoms 2.9
dry eye 2.8
hepatosplenomegaly 2.8
muscle cramps 2.8
DNA marker 2.8
splenomegaly 2.7
dry skin 2.6
tense 2.5
urinary frequency 2.5
abnormal gait 2.5
decreased appetite 2.4
starvation 2.4
memory loss 2.4
pallor 2.3
tingling 2.3
apathy 2.2
skin damage 2.0
anorexia 2.0
bloating 1.9
incoordination 1.8
overweight 1.7
exhaustion 1.7
blurred vision 1.6
myalgia 1.5
arthralgia 1.4
dysuria 1.4
respiratory distress 1.4
hypothermia 1.3
paresthesia 1.3
Wind 1.3
agitation 1.1
angina 1.1
diarrhea 1.1
polyuria 1.0
seizures 1.0
spasticity 1.0
exertional dyspnea 0.9
more...
Drug
Dimexidum 10.6
Iodophenyl 8.1
Zinc acetate 8.1
Urso 8.0
Ferrum 7.3
Zinc sulfate 7.1
Zinc sulfate 7.1
Carbadox 6.6
Gamma globulin 6.5
Tiopronin 6.5
Virginiamycin 6.5
Carbadox 6.4
Gold sodium thiomalate 6.3
Desferal 6.2
Desferal 6.1
ID2 6.1
Coconut oil 5.9
Serum albumin 5.9
Perphenazine 5.9
Albumin 5.8
Methylcellulose 5.8
DMI 5.7
Lead acetate 5.3
ascorbate 5.2
Prograf 5.2
Ethane 4.9
vitamin E 4.9
Estriol 4.8
Mesalazine 4.8
Ammonium chloride 4.7
Areca 4.5
Mezlocillin 4.5
CER 4.5
Meconium 4.3
Flavin 4.2
Everolimus 4.2
Galactose 4.2
Botox 3.9
DPA 3.9
Methylene blue 3.9
Ramipril 3.8
Glutathione 3.8
Adenosine triphosphate 3.8
Hyaluronidase 3.8
Cibacron Blue 3.7
Monensin 3.7
Hyaluronidase 3.7
Neoral 3.6
Antithrombin III 3.6
ACT 3.5
Vitamin E 3.5
Levonorgestrel 3.5
Clofibrate 3.5
L-tyrosine 3.4
Fructose 3.3
ROC 3.3
Depo-Provera 3.3
Rutin 3.3
Gel 3.1
DMSA 3.1
Heme 3.0
Riboflavin 3.0
CIA 3.0
Simvastatin 2.9
CPR 2.9
Diurnal 2.9
PTC 2.8
Norplant 2.8
Methylprednisolone 2.8
Aprotinin 2.8
ALA 2.7
Sodium nitroprusside 2.7
IFN-beta 2.6
Vitamin A 2.6
ROS 2.6
Diphenhydramine 2.6
DMAP 2.5
Aloe 2.4
Vitamin B12 2.3
CCL 2.3
more...
Enzyme
ceruloplasmin 12.6
ureidoglycolate hydrolase 9.6
guanosine deaminase 9.3
ureidoglycolate lyase 8.2
ascorbate oxidase 8.2
AO1 7.4
bilirubin oxidase 7.2
phosphatidylinositol phospholipase C 7.0
esterase D 7.0
lysyl oxidase 7.0
CPL 6.9
diamine oxidase 6.8
serum carnosinase 6.8
paraoxonase 6.7
oviductin 6.7
penicillopepsin 6.7
pantothenate kinase 6.7
tripeptidase 6.6
prolinase 6.5
CCS1 6.3
CCS 6.2
paraoxonase 6.1
nicotinamide N-methyltransferase 6.1
cystathionine beta-lyase 6.0
laccase 6.0
prolyl-tRNA synthetase 5.9
superoxide dismutase 5.9
alpha-N-acetylglucosaminidase 5.7
glutathione peroxidase 5.7
carnosinase 5.7
coproporphyrinogen oxidase 5.6
NADH peroxidase 5.6
catechol oxidase 5.5
phenol oxidase 5.5
coproporphyrinogen III oxidase 5.1
6-phosphogluconate dehydrogenase 5.1
6-phosphogluconate dehydrogenase 5.1
ferrochelatase 5.1
catalase 5.1
ribonucleotide reductase 5.0
aspartoacylase 5.0
SNO 5.0
Lod 5.0
ribonucleotide reductase 5.0
galactose oxidase 4.9
methane monooxygenase 4.9
C3 convertase 4.9
cytochrome oxidase 4.8
glutathione reductase 4.8
cysteine dioxygenase 4.8
delta-aminolevulinic acid dehydratase 4.8
oxytocinase 4.7
aconitase 4.6
tyrosinase 4.6
TMT 4.6
lysozyme 4.5
methylamine dehydrogenase 4.5
phosphoglucomutase 4.5
xanthine oxidase 4.5
dopamine beta-hydroxylase 4.5
gamma-glutamyl transpeptidase 4.5
PI-PLC 4.5
CDH 4.5
15-lipoxygenase 4.4
sucrase-isomaltase 4.4
flavin reductase 4.4
dimethylarginine dimethylaminohydrolase 4.4
nitrite reductase 4.3
branching enzyme 4.3
nitrite reductase 4.3
nitrite reductase 4.3
phosphoglycerate dehydrogenase 4.3
ferredoxin reductase 4.3
acetoacetyl-CoA thiolase 4.3
ALA synthase 4.2
proteinase-3 4.2
aspartate aminotransferase 4.1
sorbitol dehydrogenase 4.1
PAM 4.1
alanine aminotransferase 4.1
more...
Compound
6,8-Dihydroxypurine 11.6
MoO2S2 10.0
C8H10O3 10.0
p-Hydroxymandelic acid 9.6
MoS4 9.3
Homocystine 8.8
Estradiol dipropionate 8.7
36L 8.5
Neocuproine 8.4
Rhodanine 8.2
Orcinol 8.2
TETA 8.2
Vindoline 8.0
Bufotenine 7.9
Coniferyl alcohol 7.9
Zinc acetate 7.8
Versene 7.8
C3H7NO 7.6
Anserine 7.6
Fangchinoline 7.6
Bathocuproine 7.5
Infecundin 7.5
Methylxanthine 7.3
Diamant 7.3
Nickel chloride 7.2
13-cis-Retinoic acid 7.2
CPL 7.2
Pingyangmycin 7.2
DPS 7.1
copper 7.1
Zinc sulfate 7.0
Copper sulfate 6.9
Proflavine 6.9
Pinitol 6.9
Lynestrenol 6.8
Promazine 6.7
Desogestrel 6.7
Acephate 6.5
Deoxyribose 6.3
Castanospermine 6.3
Carbimazole 6.3
20-OH-LTB4 6.3
IDPN 6.3
Mimosine 6.3
RBA 6.3
Desferal 6.2
Ehrlich's reagent 6.2
Thiram 6.2
Mimosine 6.2
KDN 6.2
CCS 6.1
20-COOH-LTB4 6.1
1-Methyl-4-phenylpyridinium 6.1
Fast Blue B 6.1
Biuret 6.1
Umbelliferone 6.0
Thiram 6.0
Dehydroascorbic acid 6.0
8-hydroxyguanosine 6.0
DPA 6.0
DPA 6.0
DPA 6.0
DPA 6.0
DPA 6.0
iron 5.9
ethyl palmitate 5.8
TLA 5.8
Virginiamycin 5.8
SD 25 5.8
3,4-dihydroxybenzaldehyde 5.7
DMI 5.7
DMI 5.7
Cerulenin 5.5
Saxitoxin 5.5
Coomassie Brilliant Blue G 5.5
DFO 5.4
alpha-Tocopherol 5.4
Methoxychlor 5.4
Benzidine 5.4
3,4-dihydroxybenzaldehyde 5.3
more...