Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.16.3.1 (ceruloplasmin)
 5,074 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ceruloplasmin 4144
ferroxidase 862
transferrin 751
ferritin 530
albumin 509
superoxide dismutase 500
haptoglobin 433
Ceruloplasmin 320
Sep 309
catalase 293
glycoprotein 264
C-reactive protein 201
Mol 191
hemoglobin 189
glutathione peroxidase 184
fibrinogen 171
Wilson disease 155
ATP7B 128
IgA 127
alpha 1-antitrypsin 121
metallothionein 112
SOD 100
alkaline phosphatase 94
prealbumin 93
insulin 91
hephaestin 90
GSH 87
lysozyme 80
hemopexin 77
myeloperoxidase 73
Ferritin 73
serum albumin 71
ATPase 67
serum protein 66
EPR 60
IL-6 57
alpha-1-antitrypsin 57
cytokine 56
lactoferrin 56
peroxidase 55
MRI 54
serum amyloid A 51
transferrin receptor 50
polypeptide 50
alpha2-macroglobulin 48
SDS 46
aspartate aminotransferase 45
alpha-2-macroglobulin 45
glutathione reductase 43
ATP7A 43
Albumin 43
tumor necrosis factor 41
lactate dehydrogenase 41
alanine aminotransferase 40
HDL 40
collagen 39
Pol 38
lipopolysaccharide 38
antichymotrypsin 38
retinol-binding protein 37
antioxidant enzyme 35
She 35
cytochrome c oxidase 34
ceruloplasmin mRNA 34
Transferrin 33
interleukin-6 32
TNF 32
fibronectin 32
membrane-bound 31
transthyretin 31
plasminogen 29
Ferroxidase 28
xanthine oxidase 28
diamine oxidase 27
CRP 27
HFE 27
lysyl oxidase 26
microsomal 26
prothrombin 26
alpha1-acid glycoprotein 26
reductase 26
factor VIII 25
lamp 25
DMT1 25
apoE 25
tyrosinase 25
alpha-fetoprotein 24
endoplasmic reticulum 24
Pseudomonas 24
ESR 24
alpha-1 antitrypsin 23
heme oxygenase-1 23
paraoxonase 23
hemochromatosis 23
Hephaestin 23
heavy chain 23
sex hormone binding globulin 23
lectin 22
IL-1 22
Superoxide dismutase 21
copper transport protein 21
protease inhibitor 21
interferon 21
Haptoglobin 21
amylase 21
divalent metal transporter 1 21
cage 21
ferroportin 1 21
LPS 21
oxidoreductase 20
amyloid precursor protein 20
clusterin 20
TOF 20
CSF 20
gut 20
LEC 19
erythroid 19
ROS 19
thrombin 19
ATP 19
SOD1 18
ICP 18
esterase 18
vitamin D-binding protein 17
mer 17
apolipoprotein 17
sex hormone-binding globulin 17
glucose-6-phosphate dehydrogenase 17
thymus 17
UTR 17
IgE 17
amine oxidase 16
antithrombin III 16
neuraminidase 16
ANOVA 15
arylesterase 15
cytochrome c 15
DNA-binding protein 15
B12 15
ribonucleotide reductase 15
IL-8 15
acid phosphatase 14
transferrin receptor 2 14
thyroxine-binding globulin 14
CTR1 14
apolipoprotein B 14
apolipoprotein E 14
X-linked 14
casein 13
caspase-3 13
creatine kinase 13
glutathione S-transferase 13
antithrombin 13
carbonic anhydrase 13
cytochrome 12
carp 12
nitric oxide synthase 12
superoxide dismutase 1 12
myoglobin 12
Rec 12
more...
Disease
Wilson's disease 329
cancer 188
anemia 171
diabetes 151
Menkes 98
cirrhosis 98
iron overload 98
Alzheimer's disease 95
tumor 89
GSH 87
liver disease 74
Parkinson's disease 67
hepatocellular carcinoma 66
rheumatoid arthritis 66
iron deficiency 64
hepatitis 62
Copper deficiency 61
atherosclerosis 54
dementia 51
SDS 46
depression 43
arthritis 42
Evans 41
malnutrition 36
hemochromatosis 35
cardiovascular disease 34
myocardial infarction 33
hemolytic anemia 30
carcinoma 29
obesity 28
cornea 28
hypertension 27
ischemia 26
DMT1 26
neutropenia 26
cognitive impairment 25
stroke 22
breast cancer 22
type 2 diabetes 21
chronic hepatitis 21
chronic liver disease 21
genetic disorder 20
tuberculosis 20
infectious diseases 20
parkinsonism 20
osteoarthritis 19
plaque 19
lung cancer 18
systemic lupus erythematosus 18
proteinuria 18
sepsis 18
cholestasis 18
ICP 18
multiple sclerosis 18
renal disease 17
neurological disease 17
Hodgkin's disease 17
fatty liver 17
acute hepatitis 17
chronic active hepatitis 17
SEM 17
primary biliary cirrhosis 17
disorders of copper metabolism 16
osteoporosis 16
hyperglycemia 16
pneumonia 16
malabsorption 16
metastases 16
heart failure 15
sepsis 15
bacterial infection 15
preeclampsia 15
microcytic anemia 15
AIN 15
cold 14
metabolic disorder 14
hepatitis B 14
epilepsy 14
leukopenia 14
cataract 14
leukemia 14
hypercholesterolemia 13
asthma 13
uterus 13
Mycobacterium 13
influenza 13
iron deficiency anemia 13
squamous cell carcinoma 12
thrombocytopenia 12
hereditary hemochromatosis 12
chronic renal failure 12
psoriasis 12
pulmonary tuberculosis 12
malaria 12
viral hepatitis 12
carcinogenesis 12
acute myocardial infarction 12
macular degeneration 12
amyotrophic lateral sclerosis 12
coronary heart disease 12
multiple myeloma 11
hyperlipidemia 11
HIV 11
movement disorder 11
dysphagia 11
abortion 11
renal failure 11
ovarian cancer 11
chronic pancreatitis 10
Huntington's disease 10
autism 10
metabolic syndrome 10
schizophrenia 10
glioma 10
meningitis 10
gastric cancer 10
hypothyroidism 10
aqueous humor 10
hypercupremia 10
sickle cell disease 10
psychosis 10
liver fibrosis 9
autoimmune disease 9
glucose intolerance 9
adenocarcinoma 9
cystic fibrosis 9
pancytopenia 9
neuroblastoma 9
Infection 9
retinopathy 9
neuropathy 9
mastitis 9
dyslipidemia 9
myocardial ischemia 9
fits 9
alcoholism 8
Down syndrome 8
colon cancer 8
nephrotic syndrome 8
melanoma 8
hepatic encephalopathy 8
developmental delay 8
dyskinesia 8
retinitis pigmentosa 8
encephalopathy 8
coronary artery disease 8
West 8
Graves' disease 8
Hallervorden-Spatz disease 8
tumor growth 8
gallstones 8
chronic obstructive pulmonary disease 7
renal cell carcinoma 7
glomerulonephritis 7
Epstein 7
hemosiderosis 7
mental retardation 7
bipolar disorder 7
sarcoma 7
laryngeal cancer 7
more...
Symptom
tremor 46
Kayser-Fleischer ring 30
dystonia 29
seizures 26
dysarthria 25
ataxia 23
starvation 21
pain 20
diarrhea 19
cerebellar ataxia 15
overweight 14
hepatomegaly 12
weakness 11
hypotonia 11
splenomegaly 10
fatigue 10
myoclonus 9
anesthesia 9
anorexia 9
respiratory distress 8
vomiting 8
hyperoxia 7
hypothermia 7
abdominal pain 7
exhaustion 7
angina 7
nausea 6
bradykinesia 6
HSA 5
headache 5
hepatosplenomegaly 5
colic 5
chorea 5
athetosis 4
agitation 4
ataxic gait 4
asterixis 4
arthralgia 3
emaciation 3
memory loss 3
dry eye 3
collapse 3
myalgia 3
hypoproteinemia 3
apathy 3
constipation 3
cough 3
pallor 2
sleepiness 2
torticollis 2
paresthesia 2
acidity 2
intention tremor 2
clumsiness 2
functional recovery 2
menopausal symptoms 2
spasticity 2
renal colic 2
neurological disability 2
tense 2
blepharospasm 2
muscle rigidity 2
dizziness 2
DNA marker 1
loss of balance 1
drooling 1
tinnitus 1
dyspnea 1
paresis 1
dysuria 1
Ill 1
right upper quadrant pain 1
disturbed speech 1
insomnia 1
blurred vision 1
numbness 1
polyuria 1
abnormal gait 1
Wind 1
erythema 1
tingling 1
stigma 1
Behavioral symptoms 1
hunger 1
hypercapnia 1
personality change 1
urethral discharge 1
excessive sweating 1
incoordination 1
skin damage 1
partial seizure 1
cachexia 1
forgetfulness 1
thinning 1
chills 1
decreased appetite 1
urinary frequency 1
dry skin 1
pedal edema 1
swollen joints 1
chest pain 1
bloating 1
epigastric pain 1
Lasegue's sign 1
meningism 1
exertional dyspnea 1
muscle cramps 1
Gastrointestinal symptoms 1
No adverse effect 1
Climacteric symptoms 1
cyanosis 1
Drug
ascorbate 136
vitamin E 84
Albumin 43
lysine 25
CSF 20
Gel 20
ROS 19
DMI 18
NADH 12
ROC 12
Glutathione 12
Serum albumin 12
Nephron 9
IL-2 9
Dermatol 9
IFN-gamma 7
Vitamin E 6
Cardiovasc 6
Nephron 6
Ethanol 5
MAP 5
citric acid 4
L-tyrosine 4
Indomethacin 4
Monit 4
ACT 4
Leaf 4
Heme 4
EE2 4
Galactose 3
ID2 3
DPA 3
Fructose 3
Desferal 3
Vitamin A 3
IFN-beta 3
Desferal 3
Asn 3
Histamine 3
Methylene blue 3
ALA 3
nitroglycerin 2
Zinc sulfate 2
Spectrum 2
ZnO 2
lactose 2
Zinc sulfate 2
Alanine 2
Diurnal 2
ENT 2
Monensin 2
Portal 2
CPR 2
CAM 2
Everolimus 2
Zinc acetate 2
Simvastatin 2
Norplant 2
Bifidobacterium 2
CaCl2 2
caffeine 2
CaCl2 2
TiO2 2
Adenosine triphosphate 2
PTC 2
niacin 2
CaCl2 2
Mutagen 2
Hyaluronidase 1
Ethane 1
Depo-Provera 1
Retinoic acid 1
Carbadox 1
Ginseng 1
Fragment 1
HCH 1
EPA 1
Gamma globulin 1
Growth hormone 1
Perphenazine 1
Meconium 1
Gold sodium thiomalate 1
DMAP 1
ETS 1
Captopril 1
Pronase 1
CTX 1
Silica 1
Areca 1
Mesalazine 1
Dial 1
DHT 1
Cibacron Blue 1
Ammonium chloride 1
Prograf 1
CER 1
Rutin 1
Lead acetate 1
SiO2 1
CIA 1
Sodium nitroprusside 1
ampicillin 1
Fluorescein 1
Ramipril 1
Dakar 1
Aprotinin 1
DNase I 1
Urso 1
Flavin 1
Biopolymers 1
Neoral 1
Methylcellulose 1
Methylprednisolone 1
NBT 1
Levonorgestrel 1
Vitamin K 1
Nitric Oxide 1
Hyaluronidase 1
Dimexidum 1
Carbadox 1
Spectrum 1
Mezlocillin 1
Fluorescein 1
Tacrolimus 1
Coconut oil 1
Diphenhydramine 1
Adriamycin 1
THF 1
DMSA 1
Ringer's solution 1
DHT 1
Iodophenyl 1
Virginiamycin 1
Vitamin B12 1
Botox 1
CCL 1
Ferrum 1
Antithrombin III 1
Estriol 1
Tiopronin 1
Clofibrate 1
ADR 1
Aloe 1
Riboflavin 1
NAG 1
Growth hormone 1
Enzyme
ceruloplasmin 5074
superoxide dismutase 566
catalase 297
glutathione peroxidase 186
peroxidase 129
alkaline phosphatase 94
lysozyme 80
ATPase 71
alanine aminotransferase 71
aspartate aminotransferase 61
trypsin 46
laccase 46
diamine oxidase 44
lactate dehydrogenase 44
glutathione reductase 43
cytochrome oxidase 40
tyrosinase 36
ascorbate oxidase 36
gamma-glutamyl transpeptidase 32
xanthine oxidase 30
paraoxonase 29
lysyl oxidase 25
monoamine oxidase 25
paraoxonase 23
thrombin 19
cholinesterase 19
glutathione S-transferase 19
neuraminidase 19
glucose-6-phosphate dehydrogenase 18
acetylcholinesterase 18
ribonucleotide reductase 15
ribonucleotide reductase 15
creatine kinase 15
acid phosphatase 14
carbonic anhydrase 13
elastase 12
luciferase 11
AST 10
heme oxygenase 10
ERK 9
malate dehydrogenase 9
mitogen-activated protein kinase 9
plasmin 9
chymotrypsin 9
APC 9
collagenase 9
6-phosphogluconate dehydrogenase 8
ACE 8
6-phosphogluconate dehydrogenase 8
aconitase 7
thromboplastin 7
CCS 7
caspase-3 7
nitrite reductase 6
nitrite reductase 6
nitrite reductase 6
NO synthase 6
protein kinase 6
RNase 6
renin 6
phenol oxidase 6
RNase 6
NQO1 6
RNA polymerase 6
reverse transcriptase 6
bilirubin oxidase 6
DNase 5
esterase D 5
diaphorase 5
carboxylesterase 5
focal adhesion kinase 5
protein kinase C 5
NADPH oxidase 5
phosphoglucomutase 5
C3 convertase 5
kallikrein 5
lipoxygenase 5
NADPH oxidase 5
CPL 5
dopamine beta-hydroxylase 5
PAM 5
ferrochelatase 5
phospholipase A2 5
adenosine deaminase 4
adenylate kinase 4
alcohol dehydrogenase 4
methane monooxygenase 4
delta-aminolevulinic acid dehydratase 4
adenosine deaminase 4
isocitrate dehydrogenase 4
neutrophil elastase 4
diaphorase 4
NADPH-diaphorase 4
isocitrate dehydrogenase 4
complex I 4
pepsin 4
pantothenate kinase 4
galactose oxidase 4
beta-glucuronidase 4
tyrosine hydroxylase 4
guanylate cyclase 4
glucose-6-phosphatase 4
ACS 4
leucine aminopeptidase 4
hexokinase 4
glucose oxidase 4
phosphoglucose isomerase 4
15-lipoxygenase 4
urease 3
endoglycosidase H 3
lipase 3
glyceraldehyde-3-phosphate dehydrogenase 3
alpha-amylase 3
sucrase-isomaltase 3
cathepsin D 3
sucrase 3
TMT 3
5'-nucleotidase 3
MEK 3
sorbitol dehydrogenase 3
alpha-mannosidase 3
ALA synthase 3
sialidase 3
urease 3
succinate dehydrogenase 3
enolase 2
citrate synthase 2
histidine decarboxylase 2
SNO 2
glycerol-3-phosphate dehydrogenase 2
cathepsin G 2
xanthine dehydrogenase 2
MMP-3 2
sulfatase 2
purine nucleoside phosphorylase 2
branching enzyme 2
glutamate dehydrogenase 2
Pla 2
glutamate dehydrogenase 2
papain 2
TSA 2
CDH 2
hexosaminidase 2
sialyltransferase 2
BAL 2
glyceraldehyde-3-phosphate dehydrogenase 2
glutamine synthetase 2
aldolase 2
prolinase 2
penicillopepsin 2
ribonuclease 2
tissue plasminogen activator 2
proteasome 2
CPR 2
prolyl hydroxylase 2
P-glycoprotein 2
ribonuclease 2
phosphatidylinositol phospholipase C 2
glycerol-3-phosphate dehydrogenase 2
S1 nuclease 2
more...
Compound
copper 1969
iron 1339
zinc 451
Clin 378
oxygen 360
Dec 322
DNA 213
glucose 160
water 146
hydrogen 114
His 111
GSH 94
GSH 94
sodium 93
sulfate 87
H2O2 83
calcium 78
nitric oxide 75
selenium 71
manganese 61
phosphate 57
methionine 55
urea 55
acetate 54
retinol 53
cysteine 51
nitrogen 50
creatinine 49
Cu(II) 48
SDS 47
alanine 45
molybdenum 45
tyrosine 44
salt 36
lysine 35
ammonium 35
ethanol 34
silver 33
cadmium 33
TNF 32
EDTA 30
EDTA 30
galactose 27
leucine 26
nitrate 26
tryptophan 24
tryptophan 24
arginine 24
Ascorbic acid 24
tryptophan 24
tryptophan 24
homocysteine 24
phosphorus 24
potassium 23
Estrogen 23
superoxide radical 21
TOF 20
ATP 19
DMI 18
MDA 18
DMI 18
hydroxide 17
glutamate 16
DPA 15
DPA 15
DPA 15
DPA 15
DPA 15
DEAE 15
vitamin D 14
cobalt 14
nickel 14
hexose 14
Phe 14
Hemoglobin 14
noradrenaline 14
cyanide 14
Fibrinogen 13
Asp 12
Gly 12
threonine 12
hexose 12
NADH 12
hexose 12
PEG 12
hexose 12
glutamine 11
Malondialdehyde 11
bromide 11
serine 10
ADP 10
ADP 10
ADP 10
Vitamin E 10
TCA 10
ubiquinone 10
DFO 9
GlcNAc 9
chromium 9
NADPH 9
iodine 9
acetic acid 9
GPT 9
NADPH 9
retinoic acid 9
NH2 9
CO2 9
CdCl2 9
Estrogen 8
cAMP 8
CCl4 8
TETA 8
asparagine 8
glutamic acid 8
alloxan 8
Mg2+ 8
phosphoric acid 8
chromate 7
Thyroid 7
CAT 7
cGMP 7
CAT 7
Cholesterol 7
CCS 7
TRH 7
mercury 7
Tris 7
CAT 7
proline 7
carbonate 6
ammonia 6
HCl 6
methanol 6
phenol 6
pyrene 6
thiourea 6
PGE 6
Guo 6
GABA 6
sodium chloride 6
ACTH 6
GABA 6
Triton X-100 6
Tris 6
8-OHdG 6
Lead 6
Cardiol 6
hyaluronic acid 6
GSSG 6
glycerol 5
Curcumin 5
Uric acid 5
ACS 5
tin 5
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 5
PMA 5
hydroquinone 5
CPL 5
TSH 5
GAL 5
more...