Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.16.3.1 (
ceruloplasmin
)
5,074
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
It is found that antioxidative activity (AOA) and activity of glutathione-transferase in postmitochondrial placenta fraction of pregnant women with diabetes mellitus is lowered. Depression of AOA in placenta associated with a decrease of UDA and
ceruloplasmin
amount in blood of the newborns shows the exhaustion of the antioxidative protection system. A decrease of enzyme activity at the sorbitol way of glucose exchange (sorbitol-dehydrogenase and
aldose reductase
) in placenta reflects accumulation of sorbitol in tissue, which intensifies the damage of membrane structures in placenta.
...
PMID:[Status of the antioxidant system and sorbitol pathway of glucose metabolism in diabetes mellitus]. 823 22
