Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.16.3.1 (
ceruloplasmin
)
5,074
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Balb/c 3T3, Swiss 3T3 and
Rous sarcoma
virus transformed Balb/c 3T3 mouse embryonic fibroblasts produced
ceruloplasmin
in vitro, whereas primary cultures prepared from the Balb/c mouse embryos did not produce
ceruloplasmin
. The amount of
ceruloplasmin
synthesis by the Balb/c 3T3 cell line is enhanced by
Rous sarcoma
virus-transformation (1.5-3 fold) and by treatment with dexamethasone (about 2.4 fold). The protein was identified as
ceruloplasmin
by immunoprecipitation with
ceruloplasmin
-specific polyclonal antibody, and by similarity of peptide maps, and subunit molecular weight (135,000 dalton) to that of authentic
ceruloplasmin
from primary cultures of mouse hepatocytes.
...
PMID:The expression of ceruloplasmin, an angiogenic glycoprotein, by mouse embryonic fibroblasts. 298 67
