Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.15.1.1 (
superoxide dismutase
)
58,858
document(s) hit in 31,850,051 MEDLINE articles (0.07 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
superoxide dismutase
49069
catalase
23951
glutathione peroxidase
12361
SOD
11732
GSH
9521
glutathione reductase
4098
Sep
4044
antioxidant enzyme
3501
Mol
3496
peroxidase
3260
CAT
3192
TNF
2531
caspase-3
2288
lactate dehydrogenase
1964
tumor necrosis factor
1876
xanthine oxidase
1868
ROS
1815
MnSOD
1743
aspartate aminotransferase
1541
Bcl-2
1437
IL-6
1421
SOD1
1394
glutathione S-transferase
1384
myeloperoxidase
1362
insulin
1346
nitric oxide synthase
1175
alkaline phosphatase
1175
alanine aminotransferase
1167
inducible nitric oxide synthase
1127
Catalase
1119
NADPH
994
cytochrome c
987
ATP
945
albumin
886
heme oxygenase-1
883
Superoxide dismutase
865
Nrf2
854
GST
852
lipopolysaccharide
844
cytokine
823
more...
Disease
GSH
9521
ischemia
2182
diabetes
2110
cancer
1981
tumor
1339
amyotrophic lateral sclerosis
1250
Alzheimer's disease
871
hypertension
858
atherosclerosis
629
Parkinson's disease
599
hyperglycemia
582
cold
573
carcinogenesis
563
cerebral ischemia
487
stroke
479
NAME
473
depression
459
myocardial ischemia
420
obesity
411
cardiovascular disease
365
type 2 diabetes
360
myocardial infarction
352
cognitive impairment
310
carcinoma
294
hepatocellular carcinoma
290
sepsis
289
sepsis
277
hyperlipidemia
240
diabetic nephropathy
239
heart failure
238
breast cancer
232
neuroblastoma
224
memory impairment
222
dementia
216
fatty liver
207
SDS
204
arthritis
197
B-cell lymphoma
197
renal disease
197
colitis
184
more...
Symptom
hyperoxia
307
pain
223
anesthesia
189
seizures
179
fatigue
155
starvation
147
diarrhea
100
exhaustion
95
collapse
95
weakness
94
acidity
78
functional recovery
77
hypothermia
66
respiratory distress
66
acute stress
46
overweight
45
angina
39
skin damage
38
memory loss
37
erythema
34
hypercapnia
26
chills
26
headache
25
thinning
24
anorexia
24
tremor
23
ataxia
22
Decreased activity
19
cough
18
despair
16
cachexia
16
insomnia
13
dyspnea
13
abdominal pain
12
polyuria
12
splenomegaly
12
paresis
11
Anoxia
11
vomiting
10
stigma
10
more...
Drug
ascorbate
1985
ROS
1815
vitamin E
1447
NADH
635
Glutathione
391
Cardiovasc
292
lysine
281
Vitamin E
247
Ethanol
187
Dermatol
152
IL-2
142
Monit
138
Leaf
130
Indomethacin
125
ZnO
100
CTX
92
nitroglycerin
90
NBT
88
ALA
86
MAP
81
IFN-gamma
81
Heme
80
caffeine
70
Adriamycin
65
Angiotensin II
65
citric acid
63
CSF
63
TAC
61
Gel
61
TiO2
61
Nephron
60
Nitric Oxide
59
FAD
55
TTC
49
Rutin
46
Glycyrrhiza
45
lactose
44
Bifidobacterium
42
Nephron
40
FeCl3
40
more...
Enzyme
superoxide dismutase
58858
catalase
26426
glutathione peroxidase
12498
peroxidase
4963
glutathione reductase
4100
glutathione S-transferase
2333
alanine aminotransferase
2325
aspartate aminotransferase
2253
lactate dehydrogenase
2062
xanthine oxidase
1877
caspase-3
1778
ascorbate peroxidase
1593
alkaline phosphatase
1177
NADPH oxidase
1153
mitogen-activated protein kinase
1114
NADPH oxidase
980
creatine kinase
801
acetylcholinesterase
791
ATPase
739
AST
728
glucose-6-phosphate dehydrogenase
726
ceruloplasmin
566
NO synthase
545
lysozyme
506
NQO1
490
protein kinase
453
ERK
364
heme oxygenase
340
caspase-9
325
acid phosphatase
323
complex I
302
protein kinase C
300
NOS
287
gamma-glutamyl transpeptidase
275
tyrosinase
274
lipoxygenase
266
succinate dehydrogenase
237
AMP-activated protein kinase
230
dehydroascorbate reductase
227
cytochrome oxidase
204
more...
Compound
oxygen
15579
GSH
9816
GSH
9816
water
4942
hydrogen
4629
DNA
4360
Dec
4283
nitric oxide
4223
copper
3627
MDA
3329
CAT
3192
CAT
3192
CAT
3192
H2O2
3181
glucose
3072
TNF
2531
iron
2497
zinc
2495
sodium
2373
manganese
1736
nitrogen
1629
Clin
1544
calcium
1527
superoxide radical
1516
creatinine
1419
ethanol
1415
urea
1312
arginine
1295
cadmium
1114
acetate
1113
selenium
1096
cysteine
1071
proline
1051
GSSG
1030
salt
1010
NADPH
996
NADPH
995
ATP
945
phosphate
926
NADH
636
more...