Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.14.99.3 (heme oxygenase)
4,196 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein heme oxygenase-1 3778 HO-1 1052 erythroid 356 Mol 325 superoxide dismutase 304 Nrf2 275 HO-2 271 Sep 264 nitric oxide synthase 258 microsomal 253 catalase 240 inducible nitric oxide synthase 223 GSH 213 lipopolysaccharide 201 tumor necrosis factor 191 cytochrome P-450 180 hemoglobin 171 TNF 160 cytokine 155 glutathione peroxidase 147 ferritin 138 NADPH 133 caspase-3 127 IL-6 122 NQO1 120 cytochrome P450 113 p38 112 biliverdin reductase 109 guanylate cyclase 100 NAD 96 insulin 84 reductase 77 HO2 75 cyclooxygenase 73 quinone oxidoreductase 70 DT-diaphorase 69 heat shock protein 69 cyclooxygenase-2 68 LPS 64 antioxidant enzyme 63 HSP70 61 cytochrome 61 ATP 60 ROS 59 myeloperoxidase 59 Bcl-2 59 MAPK 59 endoplasmic reticulum 59 p65 58 IL-10 56 COX-2 55 glutathione S-transferase 53 soluble guanylyl cyclase 53 lactate dehydrogenase 52 myoglobin 51 glutathione reductase 50 HMOX1 50 P450 49 vascular endothelial growth factor 49 NF-E2-related factor 2 48 SOD 48 metallothionein 48 mitogen-activated protein 46 interleukin-6 45 glutamate-cysteine ligase 45 oxidoreductase 44 alanine aminotransferase 43 extracellular signal-regulated kinase 42 ERK1 42 NMR 42 ERK 41 haptoglobin 40 p53 40 nuclear factor (erythroid-derived 2)-like 2 40 IL-8 40 collagen 40 PI3K 39 cytochrome c 39 JNK 38 TLR4 37 more...

Disease GSH 213 ischemia 189 cancer 146 hypertension 116 diabetes 108 tumor 91 Alzheimer's disease 85 atherosclerosis 79 stroke 75 hyperbilirubinemia 64 NAME 60 sepsis 57 sepsis 57 hepatocellular carcinoma 56 depression 40 obesity 38 cardiovascular disease 38 carcinogenesis 36 hyperglycemia 36 Parkinson's disease 34 cold 32 cerebral ischemia 30 cognitive impairment 29 anemia 28 malaria 27 iron overload 24 asthma 24 myocardial ischemia 23 B-cell lymphoma 23 sickle cell disease 22 type 2 diabetes 21 neuroblastoma 21 myocardial infarction 21 metabolic syndrome 21 preeclampsia 21 neonatal jaundice 20 pulmonary hypertension 19 cirrhosis 19 multiple sclerosis 18 heart failure 18 chronic obstructive pulmonary disease 18 renal disease 17 proteinuria 17 colitis 17 leukemia 17 pheochromocytoma 17 SDS 16 carcinoma 16 adenocarcinoma 16 breast cancer 15 osteoarthritis 15 plaque 15 vascular disease 15 diabetic nephropathy 14 infectious diseases 14 acute renal failure 14 tumor growth 14 lung cancer 13 porphyria 13 fatty liver 13 subarachnoid hemorrhage 13 Mycobacterium 13 Infection 12 iron deficiency 12 tuberculosis 12 HSP 12 arthritis 12 liver disease 12 glioma 11 dementia 11 cardiomyopathy 11 rheumatoid arthritis 11 colon cancer 11 PCC 10 MCF 10 autoimmune disease 10 virus infection 10 inflammatory bowel disease 10 liver fibrosis 10 renal ischemia 10 more...

Symptom pain 45 hyperoxia 25 anesthesia 21 seizures 19 starvation 8 functional recovery 8 hypothermia 7 respiratory distress 6 hypercapnia 6 erythema 5 collapse 5 weakness 4 tremor 4 vomiting 4 diarrhea 3 splenomegaly 3 acute stress 3 memory loss 3 bradykinesia 3 anorexia 3 skin damage 3 exhaustion 3 angina 3 acute pain 3 syncope 2 nausea 2 hepatomegaly 2 overweight 2 fatigue 2 acidity 2 analgesia 2 discomfort 2 abdominal pain 2 discomfort 2 prostration 1 spasticity 1 lassitude 1 ataxia 1 Peripheral neuropathic pain 1 shortness of breath 1 HSA 1 polyuria 1 sneezing 1 hepatosplenomegaly 1 tenesmus 1 low back pain 1 forgetfulness 1 dry skin 1 Neuropathic pain 1 hypocapnia 1

Drug Heme 332 ROS 59 ALA 47 ascorbate 38 CoCl2 27 CoCl2 27 NADH 25 vitamin E 19 IFN-gamma 16 lysine 13 Dermatol 13 FAD 12 Cardiovasc 12 Glutathione 11 MAP 10 CSF 9 Angiotensin II 9 Arsenic trioxide 8 ICI 7 Nitric Oxide 7 Mutagen 6 Gel 6 Indomethacin 6 IL-2 5 Cimetidine 4 TiO2 4 ZnO 4 nitroglycerin 4 Nephron 4 Simvastatin 4 Ethanol 4 CPR 4 DNase I 4 Cimetidine 4 Nephron 3 Glucagon 3 caffeine 3 ZnCl2 3 Portal 3 Monit 3 ZnCl2 3 EE2 3 Sodium nitroprusside 3 Photofrin 3 Vardenafil 2 CTX 2 Neotrofin 2 Glycyrrhiza 2 MRC 2 Cilostazol 2 Paraffin 2 Pravastatin 2 Auranofin 2 Scopolamine 2 Methylene blue 2 Ginger 2 ampicillin 2 Albumin 2 Glycerol 2 Stannous chloride 2 Vitamin E 2 Ginseng 2 CIA 2 Kainic acid 2 PCB 2 Viagra 1 Solon 1 Glucantime 1 Axitinib 1 Mevastatin 1 Pentaerythritol tetranitrate 1 Levitra 1 Asperlin 1 Asn 1 ABC 1 Itraconazole 1 DEL 1 PE2 1 Bucillamine 1 Silica 1 more...

Enzyme heme oxygenase 4196 superoxide dismutase 340 catalase 247 mitogen-activated protein kinase 205 NQO1 152 glutathione peroxidase 150 ALA synthase 138 guanylate cyclase 126 NO synthase 116 biliverdin reductase 101 caspase-3 101 protein kinase 93 peroxidase 90 glutathione S-transferase 69 alanine aminotransferase 64 gamma-glutamylcysteine synthetase 57 NADPH oxidase 56 glutathione reductase 54 luciferase 54 lactate dehydrogenase 54 NADPH oxidase 53 ERK 48 demethylase 46 aspartate aminotransferase 42 NOS 40 ferrochelatase 39 CPR 39 AMP-activated protein kinase 38 protein kinase C 33 xanthine oxidase 25 ECH 25 phosphatidylinositol 3-kinase 25 ATPase 24 delta-aminolevulinic acid dehydratase 19 collagenase 19 UDP-glucuronosyltransferase 19 AMPK 18 proteasome 17 alkaline phosphatase 17 thioredoxin reductase 15 creatine kinase 15 AMPK 15 PARP 14 NADPH-diaphorase 13 tyrosine hydroxylase 12 diaphorase 12 peroxiredoxin 12 GSK 12 phosphoinositide 3-kinase 12 soluble epoxide hydrolase 12 reverse transcriptase 11 focal adhesion kinase 11 aryl hydrocarbon hydroxylase 11 ceruloplasmin 10 gamma-glutamyl transpeptidase 10 thrombin 10 renin 10 PKG 10 porphobilinogen deaminase 9 ornithine decarboxylase 9 complex I 9 MAP 9 IKK 8 MEK 8 AST 8 uroporphyrinogen decarboxylase 8 RNA polymerase 7 glutathione synthetase 7 adenylate cyclase 7 caspase-9 7 aldehyde dehydrogenase 7 ACE 7 aldehyde dehydrogenase 7 aldehyde dehydrogenase 7 trypsin 7 aldehyde dehydrogenase 7 aldehyde dehydrogenase 7 ascorbate peroxidase 7 ACS 7 lipase 6 more...

Compound CO2 831 oxygen 792 iron 612 nitric oxide 456 Heme 361 zinc 305 Dec 293 tin 283 DNA 239 GSH 218 GSH 218 hydrogen 181 sodium 174 water 172 TNF 160 cobalt 148 cGMP 145 arginine 137 NADPH 134 NADPH 133 glucose 131 cysteine 128 Clin 118 glutamate 107 NAD 96 NAD 96 H2O2 94 cadmium 83 nitrogen 77 calcium 75 chromium 72 His 63 Hemin 61 ATP 60 phosphate 60 delta-aminolevulinic acid 60 Hemin 56 Hemin 56 Hemin 56 Hemin 56 creatinine 50 N-acetylcysteine 48 Protoporphyrin IX 48 salt 47 ethanol 47 Tin 46 acetate 43 copper 39 Bilirubin 38 Biliverdin 36 H2S 36 MTT 36 GSSG 35 urea 34 Zinc protoporphyrin 32 tryptophan 31 potassium 31 tryptophan 31 superoxide radical 31 tryptophan 31 nicotinamide 31 tryptophan 31 aniline 31 sulfate 30 cyanide 30 alanine 29 selenium 29 methionine 28 pyrene 28 tyrosine 28 cAMP 27 Curcumin 26 NADH 25 glycerol 24 manganese 24 MDA 23 8-OHdG 23 PGE 23 dUTP 22 GMP 22 more...

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