Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.14.99.3 (heme oxygenase)
4,196 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein heme oxygenase-1 3778 HO-1 1052 erythroid 356 Mol 325 superoxide dismutase 304 Nrf2 275 HO-2 271 Sep 264 nitric oxide synthase 258 microsomal 253 catalase 240 inducible nitric oxide synthase 223 GSH 213 lipopolysaccharide 201 tumor necrosis factor 191 cytochrome P-450 180 hemoglobin 171 TNF 160 cytokine 155 glutathione peroxidase 147 ferritin 138 NADPH 133 caspase-3 127 IL-6 122 NQO1 120 cytochrome P450 113 p38 112 biliverdin reductase 109 guanylate cyclase 100 NAD 96 insulin 84 reductase 77 HO2 75 cyclooxygenase 73 quinone oxidoreductase 70 DT-diaphorase 69 heat shock protein 69 cyclooxygenase-2 68 LPS 64 antioxidant enzyme 63 more...

Disease GSH 213 ischemia 189 cancer 146 hypertension 116 diabetes 108 tumor 91 Alzheimer's disease 85 atherosclerosis 79 stroke 75 hyperbilirubinemia 64 NAME 60 sepsis 57 sepsis 57 hepatocellular carcinoma 56 depression 40 cardiovascular disease 38 obesity 38 hyperglycemia 36 carcinogenesis 36 Parkinson's disease 34 cold 32 cerebral ischemia 30 cognitive impairment 29 anemia 28 malaria 27 iron overload 24 asthma 24 B-cell lymphoma 23 myocardial ischemia 23 sickle cell disease 22 type 2 diabetes 21 preeclampsia 21 neuroblastoma 21 metabolic syndrome 21 myocardial infarction 21 neonatal jaundice 20 pulmonary hypertension 19 cirrhosis 19 heart failure 18 chronic obstructive pulmonary disease 18 more...

Symptom pain 45 hyperoxia 25 anesthesia 21 seizures 19 starvation 8 functional recovery 8 hypothermia 7 hypercapnia 6 respiratory distress 6 erythema 5 collapse 5 vomiting 4 tremor 4 weakness 4 diarrhea 3 splenomegaly 3 acute stress 3 bradykinesia 3 memory loss 3 angina 3 skin damage 3 exhaustion 3 anorexia 3 acute pain 3 syncope 2 nausea 2 hepatomegaly 2 fatigue 2 acidity 2 analgesia 2 discomfort 2 overweight 2 abdominal pain 2 discomfort 2 prostration 1 spasticity 1 lassitude 1 ataxia 1 Peripheral neuropathic pain 1 shortness of breath 1 more...

Drug Heme 332 ROS 59 ALA 47 ascorbate 38 CoCl2 27 CoCl2 27 NADH 25 vitamin E 19 IFN-gamma 16 Dermatol 13 lysine 13 Cardiovasc 12 FAD 12 Glutathione 11 MAP 10 Angiotensin II 9 CSF 9 Arsenic trioxide 8 ICI 7 Nitric Oxide 7 Indomethacin 6 Mutagen 6 Gel 6 IL-2 5 DNase I 4 TiO2 4 nitroglycerin 4 Cimetidine 4 Simvastatin 4 Cimetidine 4 CPR 4 Ethanol 4 ZnO 4 Nephron 4 ZnCl2 3 Glucagon 3 Monit 3 Photofrin 3 Sodium nitroprusside 3 caffeine 3 more...

Enzyme heme oxygenase 4196 superoxide dismutase 340 catalase 247 mitogen-activated protein kinase 205 NQO1 152 glutathione peroxidase 150 ALA synthase 138 guanylate cyclase 126 NO synthase 116 biliverdin reductase 101 caspase-3 101 protein kinase 93 peroxidase 90 glutathione S-transferase 69 alanine aminotransferase 64 gamma-glutamylcysteine synthetase 57 NADPH oxidase 56 luciferase 54 glutathione reductase 54 lactate dehydrogenase 54 NADPH oxidase 53 ERK 48 demethylase 46 aspartate aminotransferase 42 NOS 40 ferrochelatase 39 CPR 39 AMP-activated protein kinase 38 protein kinase C 33 phosphatidylinositol 3-kinase 25 ECH 25 xanthine oxidase 25 ATPase 24 collagenase 19 UDP-glucuronosyltransferase 19 delta-aminolevulinic acid dehydratase 19 AMPK 18 alkaline phosphatase 17 proteasome 17 AMPK 15 more...

Compound CO2 831 oxygen 792 iron 612 nitric oxide 456 Heme 361 zinc 305 Dec 293 tin 283 DNA 239 GSH 218 GSH 218 hydrogen 181 sodium 174 water 172 TNF 160 cobalt 148 cGMP 145 arginine 137 NADPH 134 NADPH 133 glucose 131 cysteine 128 Clin 118 glutamate 107 NAD 96 NAD 96 H2O2 94 cadmium 83 nitrogen 77 calcium 75 chromium 72 His 63 Hemin 61 delta-aminolevulinic acid 60 ATP 60 phosphate 60 Hemin 56 Hemin 56 Hemin 56 Hemin 56 more...

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