Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.99.3 (heme oxygenase)
4,196 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Heme oxygenase (decyclizing) 12.9
HO-2 11.9
5-aminolevulinate synthase 1 11.9
SNF1-like kinase 2 11.9
a disintegrin and metalloprotease domain 33 11.9
GLYCOLATE OXIDASE 1 11.9
heme oxygenase-1 11.7
Sterol O-acyltransferase 1 11.3
lipocalin-interacting membrane receptor 11.3
biliverdin reductase 11.2
HMOX1 protein 11.1
HO-1 11.0
COTE1 10.9
glutathione S-transferase alpha 1 10.9
heme oxygenase (decycling) 1 10.9
ST3GalV 10.9
HMOX2 10.9
Signal-regulatory protein alpha 10.9
glutamate-cysteine ligase modifier subunit 10.7
HMX1 10.6
collagen, type IV, alpha 1 10.6
4EBP2 10.6
ATP6V1D 10.6
MT1L 10.3
IFP1 10.3
BTBD2 10.3
delta-aminolevulinate synthase 10.1
HMOX1 10.0
neurofilament triplet L protein 9.9
ALAS-E 9.9
interleukin 2 receptor gamma chain 9.9
HO2 9.8
HO3 9.7
sestrin 1 9.7
mitogen-activated protein kinase kinase kinase 7 9.7
TMOD3 9.7
RAI14 9.6
101F6 9.6
BRLZ 9.6
PAG608 9.6
glutamate-cysteine ligase 9.5
MRS3/4 9.5
HOX1 9.4
SOUL 9.4
SDR2 9.4
oxidation resistance 1 9.4
surfactant protein A1 9.4
glutathione peroxidase 6 9.4
Orosomucoid 1 9.4
nuclear factor (erythroid-derived 2)-like 2 9.4
ALAS 9.2
fructose-bisphosphate aldolase C 9.2
cell division cycle 25B 9.2
selectin P 9.2
P53-binding protein 9.2
v-myc myelocytomatosis viral oncogene homolog 9.2
lysosomal protein transmembrane 4 beta 9.1
PAOh1 9.1
PCBP3 9.1
KEAP1 protein 9.1
ALAS1 9.0
NF-E2-related factor 2 9.0
PCBP4 9.0
PTP36 8.9
phosphoenolpyruvate carboxykinase 2 8.9
FLVCR 8.9
Hemopexin 8.9
glutathione S-transferase A1 8.8
BTB and CNC homology 1 8.8
PIPK 8.7
SLC6A13 8.7
PSTK 8.7
RDH8 8.7
alpha-CP2 8.7
NFE2L2 8.7
Kelch-like ECH-associated protein 1 8.7
GCLM 8.7
HEMO 8.7
NQO1 8.7
glutathione S-transferase A2 8.6
quinone oxidoreductase 8.6
peroxiredoxin 1 8.6
WW domain-binding protein 2 8.6
DNAI2 8.6
thioredoxin reductase 1 8.6
PORC 8.4
Fragile histidine triad 8.4
kelch-like ECH-associated protein 1 8.4
PTX1 8.4
MT1F 8.4
NF-E2 8.4
GSTM4 8.3
collagen type I alpha 2 8.3
DRAP1 8.3
NOS-1 8.3
SESN3 8.2
Hsp70 interacting protein 8.2
hSVCT1 8.2
ferrochelatase 8.2
ferroportin 1 8.2
Nuclear respiratory factor 2 8.2
Friend leukemia virus integration 1 8.2
SRXN1 8.2
squalene monooxygenase 8.2
ferritin heavy chain 8.2
Nrf2 8.2
NVL 8.1
p32 protein 8.1
Werner syndrome helicase 8.1
p45 8.1
HCP1 8.1
nuclear respiratory factor 2 8.1
SLC15A2 8.1
ectonucleoside triphosphate diphosphohydrolase 1 8.1
ribosomal protein S3a 8.1
HCC-1 8.1
heme-binding protein 8.1
DT-diaphorase 8.0
DNAJB9 8.0
gastrokine 1 8.0
70kD 8.0
GCLC 8.0
transcription factor A, mitochondrial 8.0
breast cancer associated gene 1 8.0
Nrf3 8.0
heme synthetase 7.9
Alpha synuclein 7.9
Interleukin 11 7.9
TIEG 7.9
DES1 7.9
FSD1 7.9
Leucine-rich repeat-containing G-protein coupled receptor 5 7.8
Tumor protein p53 7.8
inducible form 7.8
porphobilinogen synthase 7.8
GD3S 7.8
beta-tubulin protein 7.8
PKM2 protein 7.8
fatty acid omega-hydroxylase 7.8
soluble guanylyl cyclase 7.8
NRF2 7.8
BACH1 7.8
JKTBP1 7.7
KEAP1 7.7
CAD protein 7.7
HOIL-1 7.7
A1A 7.7
ZnT-1 7.7
Cytochrome P450 reductase 7.7
APLP 7.7
QR1 7.7
iron regulatory protein 2 7.6
RARRES1 7.6
cystine/glutamate transporter 7.6
superoxide dismutase 1 7.6
hemopexin 7.6
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha 7.6
cullin 3 7.6
cysteine desulfhydrase 7.6
mitogen-activated protein kinase 8 7.6
poly (ADP-ribose) polymerase 1 7.6
NADPH-cytochrome P-450 reductase 7.6
kelch-like 7.6
PRKAA2 7.6
coproporphyrinogen oxidase 7.6
proton-coupled amino acid transporter 7.5
Src-like adaptor protein 7.5
MST3 7.5
cytochrome c oxidase subunit 2 7.5
KLF9 7.5
GCL 7.5
glutathione peroxidase 1 7.5
GCSh 7.5
SFTPA1 7.4
Hephaestin 7.4
ARP1 7.4
deleted in liver cancer 1 7.4
AKR7A2 7.4
small proline-rich protein 7.4
uroporphyrinogen III synthase 7.4
kelch 7.4
metal-responsive transcription factor 1 7.4
dual specificity phosphatase 1 7.4
TXNRD1 7.3
signal transducer and activator of transcription 4 7.3
hedgehog interacting protein 7.3
kynurenine 3-hydroxylase 7.3
nrf 7.3
Carnitine palmitoyltransferase I 7.3
SIRPA 7.3
ST2 protein 7.3
p32) 7.3
NACT 7.2
BI-1 7.2
TRN 7.2
ESRRB 7.2
actin beta 7.2
CD14 protein 7.2
IL-10R1 7.2
activating transcription factor 1 7.1
SLC36A1 7.1
ERO 7.1
Lipocalin 2 7.1
interleukin-10 receptor 7.1
MsrB3 7.1
PRKAA1 7.1
peroxiredoxin 4 7.1
cyclin G1 7.1
PCBP1 7.1
thymocyte antigen 7.1
duodenal cytochrome b 7.0
EA2 7.0
MTF1 7.0
GLO2 7.0
MAP3K7 7.0
HSPA1A 7.0
glutathione S-transferase pi 7.0
IQ motif containing GTPase activating protein 1 7.0
protoporphyria 7.0
erythroid 7.0
iron regulatory protein 1 7.0
Cytochrome P-450 7.0
D5 dopamine receptor 7.0
BH3 interacting domain death agonist 7.0
ANXA5 7.0
ferredoxin reductase 6.9
guanylate cyclase 6.9
delta-aminolevulinic acid dehydratase 6.9
p45 NF-E2 6.9
cytochrome P-450 6.9
GSTA4-4 6.9
HLA class I heavy chain 6.9
IIB1 6.9
DDAH-1 6.9
sirtuin 6 6.9
sequestosome 1 6.9
RBX1 6.8
Mig-6 6.8
cytochrome P450 2E1 6.8
SELP 6.8
BMK1 6.8
MT1G 6.8
AHA1 6.8
thioredoxin peroxidase 6.8
TRX1 6.8
Del1 6.8
cubilin 6.8
TIPE2 6.8
H4B 6.8
MDG-1 6.8
kidney injury molecule 1 6.8
AQP11 6.7
MT1A 6.7
CUL3 6.7
UDP glucuronosyltransferase 6.7
Williams syndrome transcription factor 6.7
BHLHE40 6.7
caveolin 1 6.7
activating transcription factor 6 6.7
caveolin 3 6.7
G0S2 6.7
ligandin 6.6
cytochrome b5 6.6
UNC5B 6.6
granulocyte chemotactic protein-2 6.6
BTL 6.6
hephaestin 6.6
ferritin light chain 6.6
PIK3C3 6.6
E1B19K 6.6
PTGER2 6.6
acetyl-CoA carboxylase alpha 6.6
ferroportin1 6.6
gamma-glutamylcysteine synthetase 6.6
GSTA3 6.6
TXN 6.6
ARE1 6.6
NRF 6.6
Aryl hydrocarbon hydroxylase 6.6
porphobilinogen deaminase 6.6
claudin 2 6.6
IP3R3 6.6
mucolipin 1 6.6
GRK4 6.6
P2Y13 6.6
G72/G30 6.6
CD91 6.6
activating transcription factor 4 6.5
G protein-coupled receptor 5 6.5
GSTA1 6.5
CDL 6.5
NQO1 protein 6.5
non-histone chromosomal protein 6.5
guanylyl cyclase 6.5
D5D 6.5
STC2 6.5
carcinoembryonic antigen-related cell adhesion molecule 1 6.5
CLCA1 6.5
GSN 6.5
CD177 6.4
GSH synthetase 6.4
protein phosphatase 2 6.4
SESN2 6.4
cystathionine gamma-lyase 6.4
EC-SOD 6.4
NRF-2 6.4
manganese-containing superoxide dismutase 6.4
FTH1 6.4
inducible nitric oxide synthase 6.4
Tuba 6.4
hsp 70 6.4
isoform 1) 6.4
C-X-C motif chemokine 10 6.4
GADD45B 6.4
factor 9 6.4
GPX2 6.4
CUD 6.4
DNA-directed RNA polymerase 6.4
FZR1 6.4
DMT1 6.4
more...
Disease
iron loading anemia 11.9
Centrilobular hepatic necrosis 10.9
Hepatoerythropoietic porphyria 9.2
Acute glaucoma 9.2
PORC 8.6
EA3 8.6
Neonatal hyperbilirubinemia 8.5
Chronic HIV infection 8.1
hemoglobinemia 7.6
crystal arthropathy 7.5
neonatal jaundice 7.4
hepatic porphyria 7.3
Toxicosis 7.0
hyperbilirubinemia 7.0
craniofrontonasal syndrome 7.0
X-linked sideroblastic anemia 7.0
cholestatic cirrhosis 6.8
nodular malignant melanoma 6.8
HFE2 6.8
kidney hypertrophy 6.8
placental disorders 6.7
ARP1 6.7
kernicterus 6.5
Placental insufficiency 6.5
Pulmonary veno-occlusive disease 6.4
Oxygen toxicity 6.4
DMT1 6.3
disorders of iron metabolism 6.3
Cardiovascular morbidity 6.2
vascular dilation 6.1
porphyria 6.1
myelinopathy 5.9
Chronic migraine 5.9
PLAT 5.9
hypochromic anemia 5.9
Strongyloides stercoralis infection 5.8
POH 5.8
CSE 5.6
hemoglobinuria 5.6
Carotid body 5.6
Carotid body 5.6
Carotid body 5.6
Estrogen deficiency 5.5
Hepatopulmonary syndrome 5.5
GSH 5.4
Diabetic neuropathy 5.4
CAPA 5.3
endotoxic shock 5.2
Krabbe disease 5.2
vitamin C deficiency 5.2
HSP 5.2
acute intermittent porphyria 5.1
NAME 5.1
Dubin-Johnson syndrome 5.1
vitamin B6 deficiency 5.1
Retinal degeneration 5.0
Crigler-Najjar syndrome 5.0
FIP 5.0
Hallervorden-Spatz disease 5.0
renal ischemia 4.9
Plasmodium falciparum infection 4.9
Enzyme inhibition 4.9
iron overload 4.9
pregnancy disorder 4.9
refractory cancer 4.8
diabetic cardiomyopathy 4.8
erythropoietic protoporphyria 4.8
hemangiomatosis 4.8
amelanotic melanoma 4.7
AOS 4.7
testicular dysfunction 4.7
EGC 4.7
tyrosinemia 4.6
Rocky Mountain spotted fever 4.6
Gilbert 4.6
Intestinal ischemia 4.6
Brain stem 4.6
genetic hypertension 4.6
GALT 4.5
pneumonic plague 4.5
endocardial fibroelastosis 4.5
pancreatic fibrosis 4.5
Cerebral malaria 4.4
Menkes 4.4
FIP 4.4
Acute liver failure 4.4
Liver regeneration 4.4
microcytic anemia 4.4
Endothelial dysfunction 4.3
lipidosis 4.3
monocytic leukemia 4.3
Vascular dementia 4.3
nasal allergy 4.3
sideroblastic anemia 4.3
labyrinthitis 4.3
ABO incompatibility 4.3
Bronchiolitis obliterans 4.2
siderosis 4.2
cerebral vasospasm 4.2
hereditary hemochromatosis 4.2
acute arthritis 4.2
Gitelman syndrome 4.2
Atopic 4.1
histiocytic lymphoma 4.1
Allergic asthma 4.1
CEP 4.1
PMC 4.0
Alcoholic liver disease 4.0
ABS 4.0
immunotoxicity 4.0
Tumour necrosis 4.0
ischemia 4.0
neonatal asphyxia 3.9
Li-Fraumeni syndrome 3.9
PARK2 3.9
Bartter's syndrome 3.9
Friedreich's ataxia 3.9
Cornelia de Lange syndrome 3.8
sickle cell disease 3.8
Peripheral arterial disease 3.8
Class III malocclusion 3.8
CNF 3.8
CSA 3.7
cerebral ischemia 3.7
SCD 3.7
acute chest syndrome 3.7
vitiligo 3.7
vascular obstruction 3.7
SIRS 3.7
iron deficiency 3.7
PCC 3.7
hypertension in pregnancy 3.7
Placenta 3.6
thiamine deficiency 3.6
opisthorchiasis 3.6
Focal segmental glomerulosclerosis 3.6
obstructive airway disease 3.6
AEM 3.6
Kearns-Sayre syndrome 3.6
Solitary fibrous tumor 3.6
Diabetic foot 3.6
Frey 3.5
reticuloendotheliosis 3.5
spotted fever 3.5
Darier's disease 3.5
erythroleukemia 3.5
hemochromatosis 3.5
Pulmonary arterial hypertension 3.5
preeclampsia 3.5
Tic 3.4
histiocytic lymphoma 3.4
B-cell lymphoma 3.4
thalassemia major 3.4
gas gangrene 3.4
OHD 3.3
brain edema 3.3
COL2A1 3.3
Hepatotoxicity 3.3
systemic candidiasis 3.3
diabetic nephropathy 3.3
aldosteronism 3.3
CAN 3.3
AIN 3.2
FMD 3.2
hyperhomocysteinemia 3.2
hyperglycemia 3.2
hypertensive heart disease 3.2
Fanconi syndrome 3.2
lymphosarcoma 3.2
liver fibrosis 3.2
ischemic optic neuropathy 3.2
porphyria cutanea tarda 3.1
DM2 3.1
pheochromocytoma 3.1
HGF 3.1
brain disorder 3.1
Buerger's disease 3.1
diabetic neuropathy 3.1
Malignant transformation 3.1
FBS 3.1
polycythemia 3.1
acute renal failure 3.1
nonmelanoma skin cancer 3.1
hyperosmolality 3.1
subarachnoid hemorrhage 3.1
AIS 3.1
Familial hypercholesterolemia 3.1
sepsis 3.0
adult respiratory distress syndrome 3.0
small lymphocytic lymphoma 3.0
corneal edema 3.0
glomerulosclerosis 3.0
hemolytic anemia 3.0
HPA 3.0
homocystinuria 3.0
degenerative disease 3.0
iron deficiency anemia 3.0
FFM 3.0
pulmonary hypertension 3.0
atherosclerosis 3.0
salmonellosis 2.9
Spleen 2.9
sarcoma 180 2.9
Fanconi 2.9
PAF 2.9
MIP 2.9
RDS 2.9
sepsis 2.9
fatty liver 2.8
urinary tract obstruction 2.8
HES 2.8
overnutrition 2.8
hepatic encephalopathy 2.8
acute tubular necrosis 2.8
dysentery 2.8
Pineal 2.8
HELLP syndrome 2.8
LDLR 2.8
Cirrhosis 2.8
HOS 2.8
arteriosclerosis 2.8
herniated disc 2.8
fear and anxiety 2.8
methemoglobinemia 2.7
ICH 2.7
vascular disease 2.7
colitis 2.7
metabolic syndrome 2.7
typhus 2.7
cholestasis 2.7
macular degeneration 2.7
LAP 2.7
erythrocytosis 2.6
diphtheria 2.6
cognitive impairment 2.6
hepatocellular carcinoma 2.6
PDE 2.6
CNS diseases 2.6
Alzheimer's disease 2.5
neuroblastoma 2.5
bronchopulmonary dysplasia 2.5
myocardial ischemia 2.5
Brucella melitensis 2.5
photosensitivity 2.5
Ischemic stroke 2.5
erectile dysfunction 2.4
toxic shock syndrome 2.4
proteinuria 2.4
EIA 2.4
MMA 2.4
INS 2.4
listeriosis 2.4
FMD 2.4
ileus 2.4
DES 2.4
hypertension 2.4
uremia 2.4
anterior myocardial infarction 2.3
Blocking 2.3
Evans 2.3
portal hypertension 2.3
reflux esophagitis 2.3
gallbladder cancer 2.3
nephrosis 2.3
Adenovirus 2.3
senile dementia 2.3
Brucella abortus 2.3
morbid obesity 2.3
clear cell carcinoma 2.3
scabies 2.2
pleurisy 2.2
chronic obstructive pulmonary disease 2.2
systolic hypertension 2.2
folate deficiency 2.2
malaria 2.2
oligodendroglioma 2.2
ocular hypertension 2.2
Nonalcoholic fatty liver 2.2
acute hepatitis 2.1
cardiovascular disease 2.1
dyslipidemia 2.1
mastocytoma 2.1
pulmonary fibrosis 2.1
acute pancreatitis 2.1
leptospirosis 2.1
pulmonary edema 2.1
alcoholic fatty liver 2.1
carcinogenesis 2.1
status epilepticus 2.1
amnesia 2.0
idiopathic pulmonary fibrosis 2.0
Parkinson's disease 2.0
anemia 2.0
hypersensitivity pneumonitis 2.0
disc degeneration 2.0
cardiomyopathy 2.0
emphysema 2.0
lymphoblastic leukemia 2.0
allergic rhinitis 2.0
NHC 2.0
stroke 2.0
babesiosis 1.9
myeloid leukemia 1.9
Niemann-Pick 1.9
aqueous humor 1.9
melioidosis 1.9
carcinosarcoma 1.9
clinical depression 1.9
thalassemia 1.9
NPC 1.9
acute disease 1.9
Kawasaki disease 1.9
EDA 1.9
RSV infection 1.9
WRN 1.8
chlorosis 1.8
cirrhosis 1.8
bacterial pneumonia 1.8
NOD 1.8
Wiskott-Aldrich syndrome 1.8
more...
Symptom
Peripheral neuropathic pain 7.9
hyperoxia 5.2
lassitude 4.7
prostration 4.4
tenesmus 4.0
skin damage 3.9
forgetfulness 3.5
bradykinesia 3.3
dry skin 2.9
memory loss 2.7
acute pain 2.5
hypercapnia 2.5
Neuropathic pain 2.4
acute stress 2.3
functional recovery 2.2
hypocapnia 2.2
sneezing 2.0
hypothermia 1.6
erythema 1.5
hepatomegaly 1.4
HSA 1.3
polyuria 1.3
starvation 1.3
respiratory distress 1.2
splenomegaly 1.2
seizures 0.8
hepatosplenomegaly 0.8
exhaustion 0.7
anorexia 0.7
tremor 0.7
syncope 0.7
shortness of breath 0.5
anesthesia 0.5
collapse 0.4
pain 0.4
spasticity 0.2
angina 0.1
acidity 0.0
vomiting -0.1
weakness -0.3
low back pain -0.4
discomfort -0.6
nausea -0.6
discomfort -0.7
overweight -0.8
analgesia -0.9
abdominal pain -1.0
ataxia -1.1
diarrhea -1.3
fatigue -1.8
Drug
Asperlin 11.3
P-Nitrophenol 10.9
Mesoheme 10.6
Neotrofin 10.3
Heme 9.7
Stannous chloride 8.5
Pentaerythritol tetranitrate 8.4
Motexafin gadolinium 8.2
MCZ 7.8
Glutethimide 7.8
Bucillamine 7.6
Gly-Tyr-Gly 7.5
Mevastatin 7.5
Amlexanox 7.4
MCZ 7.4
CoCl2 7.4
CoCl2 7.4
Solon 7.2
Aluminum chloride 7.1
Levitra 7.0
ALA 7.0
Butaprost 6.9
Levitra 6.7
Gold sodium thiomalate 6.6
Vardenafil 6.4
Deuterium oxide 6.4
Glybenclamide 6.3
Safflower 5.9
Zevalin 5.9
Axitinib 5.8
Vinpocetine 5.7
ROX 5.7
Arsenic trioxide 5.6
Pentostam 5.5
3-Methyladenine 5.5
Auranofin 5.5
Agomelatine 5.4
Fenoldopam 5.3
Camphor 5.3
Camphor 5.3
Tranilast 5.2
Cilostazol 5.2
NOV 5.2
PE2 5.1
Glucantime 5.0
Ginger 5.0
Desferal 4.9
metformin hydrochloride 4.9
Photofrin II 4.9
KCL 4.8
Guanethidine 4.8
Desferal 4.8
Photofrin 4.6
Duloxetine 4.6
Kainic acid 4.6
Sodium nitroprusside 4.5
ROS 4.5
Flavin 4.5
DEL 4.5
HPMPC 4.4
Limonene 4.4
Nitric Oxide 4.4
Tao 4.3
CIA 4.3
Cimetidine 4.2
Pravastatin 4.2
Simvastatin 4.2
Cimetidine 4.2
CPR 4.2
ZnCl2 4.1
ZnCl2 4.1
Epigallocatechin 4.1
Rosuvastatin 4.1
FAD 4.0
Viagra 4.0
Glutathione 4.0
Glutamic acid 3.9
Angiotensin II 3.7
Viagra 3.7
ascorbate 3.6
Methylene blue 3.6
Scopolamine 3.5
Rutin 3.5
Domperidone 3.5
Colistin 3.5
Glycyrrhiza 3.4
ICI 3.3
Rosiglitazone 3.2
Ginseng 3.2
BoNT/A 3.1
NADH 3.1
Aprotinin 3.1
vitamin E 3.0
Mutagen 2.9
Ketoconazole 2.9
Indomethacin 2.8
Paraffin 2.8
Clopidogrel 2.8
Hypaque 2.8
Glycerol 2.7
Gefitinib 2.7
Hypaque 2.6
Glucagon 2.6
Pronase 2.5
Lovastatin 2.5
FeCl3 2.5
Portal 2.4
Vitamin K 2.4
Sorafenib 2.3
GEO 2.3
MAP 2.3
Vitamin E 2.2
MRC 2.1
9-THC 2.1
PTC 2.1
IFN-gamma 2.1
Parkin 2.0
TTC 2.0
Parkin 2.0
Itraconazole 1.9
ADR 1.9
-deoxyadenosine 1.9
DNase I 1.9
Propofol 1.8
PCB 1.8
NAG 1.8
nitroglycerin 1.8
Silica 1.7
Albumin 1.7
Ethanol 1.6
Gel 1.6
pyridoxal phosphate 1.6
Fraction 1.6
EE2 1.5
ETS 1.5
Alanine 1.4
TiO2 1.4
IFN-beta 1.3
Vitamin A 1.3
ADM 1.3
Retinoic acid 1.2
ZnO 1.1
CSF 1.1
Kenyan 1.1
niacin 1.0
p75 1.0
Nephron 0.9
Nephron 0.8
lysine 0.7
Adriamycin 0.7
CTX 0.6
CTX 0.4
CTX 0.4
CAM 0.4
IL-2 0.4
caffeine 0.1
Spectrum -0.1
THF -0.1
ampicillin -0.1
ABC -0.2
Monit -0.6
Asn -0.6
Cardiovasc -1.1
lactose -1.1
Dermatol -1.4
Asthma -1.8
Dial -2.0
Enzyme
heme oxygenase 12.9
biliverdin reductase 11.4
phycocyanobilin:ferredoxin oxidoreductase 11.1
PebA 10.3
PebB 10.3
ALA synthase 10.0
HY2 8.6
porphobilinogenase 8.6
ferrochelatase 8.3
gamma-glutamylcysteine synthetase 8.2
glycine N-acyltransferase 7.9
choline monooxygenase 7.8
NQO1 7.5
ECH 7.5
delta-aminolevulinic acid dehydratase 7.3
coproporphyrinogen oxidase 7.2
tyrosylprotein sulfotransferase 7.1
uroporphyrinogen decarboxylase 7.0
ferredoxin reductase 6.9
guanylate cyclase 6.8
porphobilinogen deaminase 6.7
carboxypeptidase S 6.7
threonine aldolase 6.7
TSO 6.7
squalene epoxidase 6.7
NADPH:quinone oxidoreductase 6.6
cystathionine gamma-lyase 6.4
nicotinamide N-methyltransferase 6.3
glutathione synthetase 6.3
adrenodoxin reductase 6.3
glutamyl-tRNA reductase 6.2
Mg-chelatase 6.2
protochlorophyllide oxidoreductase 6.2
glutaminyl cyclase 6.2
myrosinase 6.1
polyphosphatase 6.1
methionine sulfoxide reductase 6.0
demethylase 6.0
cysteine synthase 5.9
sulfiredoxin 5.9
NADH-cytochrome b5 reductase 5.8
CPR 5.8
NO synthase 5.8
glycogenin 5.7
glutathione peroxidase 5.7
aryl hydrocarbon hydroxylase 5.7
AMP-activated kinase 5.6
protoporphyrinogen oxidase 5.6
betaine-homocysteine methyltransferase 5.6
thioredoxin reductase 5.5
tryptophan 2,3-dioxygenase 5.5
superoxide dismutase 5.5
UDP-glucuronosyltransferase 5.4
glutathione reductase 5.4
coproporphyrinogen III oxidase 5.4
cystathionine gamma-synthase 5.4
NOS 5.4
NADPH oxidase 5.4
CLK1 5.4
soluble epoxide hydrolase 5.4
kynurenine 3-monooxygenase 5.3
cystathionine beta-synthase 5.3
tyrosine decarboxylase 5.3
microsomal epoxide hydrolase 5.3
transaldolase 5.2
NADPH oxidase 5.2
peroxiredoxin 5.1
cysteine dioxygenase 5.1
catalase 5.1
ancrod 5.1
methylthioadenosine phosphorylase 5.0
3-mercaptopyruvate sulfurtransferase 5.0
indoleamine 2,3-dioxygenase 5.0
PRPP synthetase 5.0
DMT 5.0
pantothenate kinase 4.9
PKG 4.9
GalT 4.7
paraoxonase 4.7
S-adenosylmethionine decarboxylase 4.7
NADPH-diaphorase 4.7
flavin reductase 4.6
dimethylarginine dimethylaminohydrolase 4.6
MsrA 4.5
glutathione S-transferase 4.5
xanthine oxidase 4.5
ACC oxidase 4.5
AMP-activated protein kinase 4.5
paraoxonase 4.4
caspase-3 4.4
prolyl hydroxylase 4.4
fumarase 4.3
TdT 4.3
15-lipoxygenase 4.3
carboxypeptidase E 4.2
ascorbate peroxidase 4.2
methionine synthase 4.2
chloroperoxidase 4.2
alanine aminotransferase 4.2
AMPK 4.2
aspartate transcarbamylase 4.1
cyclohydrolase 4.1
aconitase 4.1
phosphatidylinositol 3-kinase 4.1
LasR 4.1
methionine synthase 4.1
mitogen-activated protein kinase 4.0
interstitial collagenase 4.0
phosphoinositide 3-kinase 4.0
diaphorase 3.9
asparagine synthetase 3.9
ceruloplasmin 3.9
angiotensin-converting enzyme 2 3.9
aspartate aminotransferase 3.9
lactate dehydrogenase 3.8
flavin-containing monooxygenase 3.8
thromboxane synthase 3.8
cytochrome P-450scc 3.8
GSK 3.7
CDH 3.7
1-hydroxylase 3.7
serine hydroxymethyltransferase 3.7
Thy1 3.6
IKK 3.6
glucose-6-phosphatase 3.6
xanthine dehydrogenase 3.6
MPP 3.6
aldehyde dehydrogenase 3.6
aldehyde dehydrogenase 3.6
aldehyde dehydrogenase 3.6
transketolase 3.6
poly(A) polymerase 3.5
3-hydroxyacyl-CoA dehydrogenase 3.5
PDH 3.5
MMP-3 3.5
AMPK 3.5
ornithine decarboxylase 3.4
luciferase 3.4
peroxidase 3.4
alanine aminopeptidase 3.4
aldehyde dehydrogenase 3.4
rhodanese 3.4
CEP 3.3
AST 3.3
apyrase 3.3
caspase-2 3.3
TACE 3.2
ubiquitin-protein ligase 3.2
caspase-2 3.2
MAP 3.2
phenol oxidase 3.2
PHD 3.1
protein kinase 3.1
diacylglycerol acyltransferase 3.1
ALDH 3.1
gamma-glutamyl transpeptidase 3.1
cathepsin K 3.0
MEKK1 3.0
arginase 3.0
aldehyde dehydrogenase 3.0
adenosine kinase 3.0
glutaminase 3.0
collagenase 3.0
PARP 3.0
acyl-CoA oxidase 3.0
MIP 3.0
diacylglycerol kinase 2.9
complex I 2.9
nucleotidase 2.9
DOPA decarboxylase 2.9
NADH dehydrogenase 2.8
caspase-9 2.8
chaperonin 2.8
proprotein convertase 2.8
CEP 2.8
GRK5 2.8
TSA 2.7
tyrosine hydroxylase 2.6
diamine oxidase 2.6
lysyl oxidase 2.6
creatine kinase 2.6
glutamine synthetase 2.6
TPP 2.6
glyceraldehyde-3-phosphate dehydrogenase 2.5
tyrosine aminotransferase 2.5
chymase 2.5
CaMKII 2.5
glucose oxidase 2.5
LPL 2.5
firefly luciferase 2.4
phenylalanine hydroxylase 2.4
acetyl-CoA carboxylase 2.4
6-phosphogluconate dehydrogenase 2.4
6-phosphogluconate dehydrogenase 2.4
TPP 2.4
histidine decarboxylase 2.4
protein kinase C 2.3
chalcone synthase 2.3
protein phosphatase 2A 2.3
glyceraldehyde-3-phosphate dehydrogenase 2.3
granzyme B 2.2
aldose reductase 2.2
PTA 2.2
proteasome 2.2
ornithine transcarbamylase 2.1
hydrogenase 2.1
succinic dehydrogenase 2.1
hydrogenase 2.1
glycerol-3-phosphate dehydrogenase 2.1
tryptophan hydroxylase 2.1
glycerol-3-phosphate dehydrogenase 2.1
S1 nuclease 2.1
prostaglandin synthetase 2.0
PDE 2.0
enolase 2.0
glyceraldehyde-3-phosphate dehydrogenase 2.0
dihydrofolate reductase 2.0
DCF 2.0
cathepsin L 1.9
BAL 1.9
ERK 1.9
caspase-1 1.9
phosphoenolpyruvate carboxykinase 1.9
phosphoenolpyruvate carboxykinase 1.8
choline acetyltransferase 1.8
CYP3A4 1.8
MMP 1.8
monoamine oxidase 1.8
hormone-sensitive lipase 1.8
lipoxygenase 1.8
phosphoglycerate kinase 1.8
glyceraldehyde-3-phosphate dehydrogenase 1.8
glyceraldehyde-3-phosphate dehydrogenase 1.8
cytochrome oxidase 1.8
PAH 1.8
citrate synthase 1.8
MEK 1.7
caspase-8 1.7
CPT 1.7
matrix metalloproteinase 2 1.7
phosphoenolpyruvate carboxykinase 1.7
sucrase 1.7
histidine kinase 1.7
DNA methyltransferase 1.6
deaminase 1.6
acid phosphatase 1.6
glucose-6-phosphate dehydrogenase 1.5
pyruvate kinase 1.5
SPC 1.5
ACE 1.5
ATPase 1.5
adenylate cyclase 1.5
DNA ligase 1.5
DNA ligase 1.5
diaphorase 1.5
alkaline phosphatase 1.4
ribonucleotide reductase 1.4
glucokinase 1.4
reverse transcriptase 1.4
ribonucleotide reductase 1.3
elastase 1.3
lipase 1.3
phosphodiesterase 1.3
transcriptase 1.3
CPT 1.3
furin 1.2
thrombin 1.2
isocitrate dehydrogenase 1.1
aldolase 1.1
CPT 1.1
pyruvate dehydrogenase 1.1
pyruvate dehydrogenase 1.1
phospholipase A2 1.1
renin 1.1
CD13 1.1
phospholipase C 1.0
nitrate reductase 1.0
nitrate reductase 1.0
nitrate reductase 1.0
nitrate reductase 1.0
nitrate reductase 1.0
tissue plasminogen activator 1.0
phospholipase D 1.0
DNase 1.0
beta-glucuronidase 1.0
phosphofructokinase 1.0
nitrate reductase 1.0
focal adhesion kinase 0.9
succinate dehydrogenase 0.9
RNase 0.9
cathepsin D 0.9
alpha-glucosidase 0.8
chitinase 0.8
calcineurin 0.8
glutamate dehydrogenase 0.8
glutamate dehydrogenase 0.8
subtilisin 0.8
thromboplastin 0.8
glutamate dehydrogenase 0.8
RNase 0.8
tyrosinase 0.7
acetylcholinesterase 0.7
transglutaminase 0.6
beta-galactosidase 0.6
invertase 0.6
RNA polymerase 0.6
chloramphenicol acetyltransferase 0.6
adenosine deaminase 0.6
adenosine deaminase 0.5
alpha-amylase 0.5
urokinase-type plasminogen activator 0.5
lysozyme 0.5
APC 0.5
pyruvate dehydrogenase 0.5
phosphorylase 0.4
trypsin 0.3
endonuclease 0.3
ribonuclease 0.2
ribonuclease 0.2
prostate-specific antigen 0.1
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Compound
4,4-diphenyl-2-butanone 12.9
C9H11N2O2 12.9
4,4-diphenyl-2-butanone 12.9
Asperlin 11.3
Zinc protoporphyrin 11.0
Aureusidin 10.9
C8H16O2 10.6
C8H16O2 10.6
Ethyl ferulate 10.6
Biliverdin 10.5
C15H20O3 10.3
C7H9N3O3 10.1
Mesoporphyrin IX 10.1
LNO2 10.0
Succinylacetone 9.8
Heme 9.6
Protoporphyrin IX 9.5
Indole-3-acetamide 9.4
L-Lysine monohydrochloride 9.4
Hemin 9.4
Hemin 9.4
Hemin 9.4
Hemin 9.4
Hemin 9.4
Caprin 9.3
Sulfuretin 9.2
Phorone 9.1
4-Methylcatechol 9.1
Phorone 9.1
Mesoporphyrin 8.9
hydroxymethylbilane 8.8
Spinasterol 8.6
Cobaltous chloride 8.6
Taraxasterol 8.6
Terconazole 8.6
Tin 8.5
Tryptanthrin 8.5
Terrein 8.4
Taurolithocholate 8.4
Saikosaponin A 8.4
delta-aminolevulinic acid 8.3
Aurothioglucose 8.3
Butein 8.2
Glutethimide 8.1
N,N'-dimethylthiourea 8.0
Ginkgolide A 8.0
LNFP III 8.0
Xanomeline 7.9
Eriodictyol 7.9
Bilirubin 7.9
Neohesperidin 7.9
Ophiobolin A 7.8
Bilobalide 7.7
PGJ2 7.6
Buthionine sulfoximine 7.6
tin 7.5
MK 571 7.5
Selenocystine 7.5
3'-UMP 7.5
Orientin 7.4
Protochlorophyllide 7.4
Aloin 7.3
1-tetradecene 7.3
Phenylhydrazine 7.2
Oxyresveratrol 7.2
CBrCl3 7.2
Ginkgolide B 7.2
BMN 7.1
Ziram 7.1
Alantolactone 7.1
DDMS 7.1
bromobenzene 7.0
Gadolinium chloride 7.0
Palmatine 7.0
Pelargonidin 7.0
Aloin 6.9
Galangin 6.9
Sinapic acid 6.9
Fisetin 6.9
S-allylcysteine 6.9
beta-Naphthoflavone 6.9
Acacetin 6.9
BSO 6.9
Diethyl maleate 6.8
AT-101 6.8
AT-101 6.8
gamma-Glutamylcysteine 6.8
AT-101 6.8
Tilorone 6.7
11,12-EET 6.7
Tangeretin 6.7
Plumbagin 6.6
Sulforaphane 6.6
TSO 6.6
Diphenyl diselenide 6.6
Pinocembrin 6.6
2-decenoic acid 6.6
Rosmarinic acid 6.6
Rosmarinic acid 6.6
4-hydroxyphenylpyruvate 6.5
SKF 525A 6.5
prostaglandin J2 6.4
Arsenite 6.4
N'-methylnicotinamide 6.4
Osthole 6.4
Withaferin A 6.4
2-cyclopenten-1-one 6.4
Cyanidin 6.4
Piceatannol 6.4
Noscapine 6.4
Hesperetin 6.3
Hydroxocobalamin 6.3
Tyrosol 6.3
PGA2 6.3
Cobalt, 6.3
8-hydroxyguanosine 6.2
NaAsO2 6.2
Danshensu 6.2
OLN 6.2
uroporphyrin I 6.2
FUR 6.1
Actinomycin 6.1
DDC 6.1
20-HETE 6.1
CO2 6.1
DDC 6.1
Piperlongumine 6.1
CeCl3 6.1
Phenethyl isothiocyanate 6.1
4-chlorobenzyl 6.0
methylarsonic acid 6.0
(-)-Epigallocatechin 6.0
Cobalt 6.0
4-phenyl-1,2,3,6-tetrahydropyridine 5.9
HEI 5.9
Oxymatrine 5.9
4-Hydroxynonenal 5.9
Catalpol 5.9
Formononetin 5.8
Dihydromyricetin 5.8
8-Br-cGMP 5.8
BIP 5.8
Rhein 5.8
DAU 5.8
Delphinidin 5.8
Polydatin 5.8
8-OHdG 5.8
NiCl2 5.8
Lansoprazole 5.7
LY 294002 5.7
Veronal 5.7
1,2,4-trichlorobenzene 5.7
Irgarol 1051 5.7
cGMP 5.7
tert-butyl hydroperoxide 5.7
Gliotoxin 5.7
DAU 5.7
Gliotoxin 5.7
ML-236B 5.7
Lycopene 5.7
Enflurane 5.7
Pyocyanin 5.6
Naringin 5.6
decarboxylated S-adenosylmethionine 5.6
PGA1 5.6
TBHQ 5.6
Carnosic acid 5.6
Honokiol 5.6
Porphyrin 5.6
alpha-Naphthoflavone 5.6
alpha-Naphthoflavone 5.6
Furazolidone 5.6
GSSG 5.6
alpha-Naphthoflavone 5.6
3GC 5.5
Porphyrin 5.5
Celastrol 5.5
3-Methyladenine 5.5
CdCl2 5.5
benzo[ghi]perylene 5.5
Exemestane 5.5
Nifurtimox 5.5
Paeonol 5.5
Geraniol 5.5
Luteolin 5.5
TMF 5.5
AA861 5.4
Clotrimazole 5.4
4-OHT 5.4
Thymoquinone 5.4
Fenoldopam 5.4
Sufentanil 5.4
DETA 5.4
Tetrabromobisphenol A 5.4
Sesamin 5.4
Pterostilbene 5.4
DMT 5.4
Geraniol 5.4
NADPH 5.4
Granisetron 5.4
NADPH 5.3
Barbiturate 5.3
cobalt 5.3
Fucoxanthin 5.3
GSH 5.3
GSH 5.3
Ferulic acid 5.3
Ferulic acid 5.3
WR-1065 5.3
Aminopyrine 5.3
Ellagic acid 5.3
superoxide radical 5.2
1,2,3,4-tetrahydroisoquinoline 5.2
Mr 30 5.2
Benznidazole 5.2
Benznidazole 5.2
Benznidazole 5.2
Oleuropein 5.2
Puerarin 5.2
Lentinan 5.2
Naringenin 5.2
Tetramethylpyrazine 5.2
NAD 5.2
Camphor 5.2
Tempol 5.2
Tauroursodeoxycholic acid 5.2
chalcone 5.2
2-nonenal 5.1
nitric oxide 5.1
Naringenin 5.1
Acetyl-L-carnitine 5.1
Selenomethionine 5.1
DFO 5.1
9-octadecenoic acid 5.1
DBCP 5.1
Allicin 5.1
DDC 5.1
Resveratrol 5.1
H2S 5.1
N-acetylcysteine 5.1
iron 5.1
Isoflavone 5.1
Eicosapentaenoic acid 5.0
Inactin 5.0
Hydroxytyrosol 5.0
Tiron 5.0
Naringin 5.0
Rottlerin 5.0
Lindane 5.0
Caffeic acid phenethyl ester 5.0
Baicalin 5.0
Selenocysteine 5.0
RBA 4.9
1,3-propanediamine 4.9
DMT 4.9
Berberine 4.9
Nitro-L-arginine 4.9
Curcumin 4.9
chromium 4.9
Desferal 4.9
Azan 4.9
Gossypol 4.9
INN 4.9
IBA 4.9
Rottlerin 4.9
Gossypol 4.9
maslinic acid 4.9
Griseofulvin 4.9
Rottlerin 4.9
Guanethidine 4.9
Griseofulvin 4.9
aniline 4.8
SAN 4.8
NAD 4.8
FMN 4.8
Astaxanthin 4.8
HgCl2 4.8
Carcinogen 4.7
Thiobarbituric acid 4.7
1-chloro-2,4-dinitrobenzene 4.7
Taurine 4.7
Phloretin 4.7
zinc 4.7
Chrysin 4.7
IBA 4.7
Cordycepin 4.7
Cordycepin 4.7
Apocynin 4.7
Cordycepin 4.7
Na2S 4.7
Fenofibrate 4.6
Oleanolic acid 4.6
Tacrine 4.6
FMNH 4.6
Alba 4.6
PCB 126 4.6
Edaravone 4.6
DPI 4.6
Kainic acid 4.6
Kainic acid 4.6
Fluvastatin 4.6
H2O2 4.5
3-(dimethylamino)propyl 4.5
TMC 4.5
Methylglyoxal 4.5
Sodium azide 4.5
celastrol 4.5
Piperine 4.5
Betamethasone 4.5
Acrolein 4.5
Titanium dioxide 4.5
1H-benzimidazole 4.5
COX 4.4
dUTP 4.4
Sevoflurane 4.4
2-methoxyphenol 4.4
Gliotoxin 4.4
ATC 4.4
Dieldrin 4.4
Kynurenic acid 4.4
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