Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.14.99.3 (
heme oxygenase
)
4,196
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Heme oxygenase (decyclizing)
12.9
HO-2
11.9
SNF1-like kinase 2
11.9
GLYCOLATE OXIDASE 1
11.9
5-aminolevulinate synthase 1
11.9
a disintegrin and metalloprotease domain 33
11.9
heme oxygenase-1
11.7
lipocalin-interacting membrane receptor
11.3
Sterol O-acyltransferase 1
11.3
biliverdin reductase
11.2
HMOX1 protein
11.1
HO-1
11.0
HMOX2
10.9
Signal-regulatory protein alpha
10.9
heme oxygenase (decycling) 1
10.9
COTE1
10.9
glutathione S-transferase alpha 1
10.9
ST3GalV
10.9
glutamate-cysteine ligase modifier subunit
10.7
4EBP2
10.6
more...
Disease
iron loading anemia
11.9
Centrilobular hepatic necrosis
10.9
Acute glaucoma
9.2
Hepatoerythropoietic porphyria
9.2
PORC
8.6
EA3
8.6
Neonatal hyperbilirubinemia
8.5
Chronic HIV infection
8.1
hemoglobinemia
7.6
crystal arthropathy
7.5
neonatal jaundice
7.4
hepatic porphyria
7.3
Toxicosis
7.0
hyperbilirubinemia
7.0
craniofrontonasal syndrome
7.0
X-linked sideroblastic anemia
7.0
cholestatic cirrhosis
6.8
HFE2
6.8
nodular malignant melanoma
6.8
kidney hypertrophy
6.8
more...
Symptom
Peripheral neuropathic pain
7.9
hyperoxia
5.2
lassitude
4.7
prostration
4.4
tenesmus
4.0
skin damage
3.9
forgetfulness
3.5
bradykinesia
3.3
dry skin
2.9
memory loss
2.7
acute pain
2.5
hypercapnia
2.5
Neuropathic pain
2.4
acute stress
2.3
functional recovery
2.2
hypocapnia
2.2
sneezing
2.0
hypothermia
1.6
erythema
1.5
hepatomegaly
1.4
more...
Drug
Asperlin
11.3
P-Nitrophenol
10.9
Mesoheme
10.6
Neotrofin
10.3
Heme
9.7
Stannous chloride
8.5
Pentaerythritol tetranitrate
8.4
Motexafin gadolinium
8.2
MCZ
7.8
Glutethimide
7.8
Bucillamine
7.6
Gly-Tyr-Gly
7.5
Mevastatin
7.5
Amlexanox
7.4
MCZ
7.4
CoCl2
7.4
CoCl2
7.4
Solon
7.2
Aluminum chloride
7.1
Levitra
7.0
more...
Enzyme
heme oxygenase
12.9
biliverdin reductase
11.4
phycocyanobilin:ferredoxin oxidoreductase
11.1
PebB
10.3
PebA
10.3
ALA synthase
10.0
HY2
8.6
porphobilinogenase
8.6
ferrochelatase
8.3
gamma-glutamylcysteine synthetase
8.2
glycine N-acyltransferase
7.9
choline monooxygenase
7.8
NQO1
7.5
ECH
7.5
delta-aminolevulinic acid dehydratase
7.3
coproporphyrinogen oxidase
7.2
tyrosylprotein sulfotransferase
7.1
uroporphyrinogen decarboxylase
7.0
ferredoxin reductase
6.9
guanylate cyclase
6.8
more...
Compound
C9H11N2O2
12.9
4,4-diphenyl-2-butanone
12.9
4,4-diphenyl-2-butanone
12.9
Asperlin
11.3
Zinc protoporphyrin
11.0
Aureusidin
10.9
C8H16O2
10.6
C8H16O2
10.6
Ethyl ferulate
10.6
Biliverdin
10.5
C15H20O3
10.3
Mesoporphyrin IX
10.1
C7H9N3O3
10.1
LNO2
10.0
Succinylacetone
9.8
Heme
9.6
Protoporphyrin IX
9.5
Indole-3-acetamide
9.4
L-Lysine monohydrochloride
9.4
Hemin
9.4
more...