Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.99.3 (heme oxygenase)
4,196 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
heme oxygenase-1 3778
HO-1 1052
erythroid 356
Mol 325
superoxide dismutase 304
Nrf2 275
HO-2 271
Sep 264
nitric oxide synthase 258
microsomal 253
catalase 240
inducible nitric oxide synthase 223
GSH 213
lipopolysaccharide 201
tumor necrosis factor 191
cytochrome P-450 180
hemoglobin 171
TNF 160
cytokine 155
glutathione peroxidase 147
more...
Disease
GSH 213
ischemia 189
cancer 146
hypertension 116
diabetes 108
tumor 91
Alzheimer's disease 85
atherosclerosis 79
stroke 75
hyperbilirubinemia 64
NAME 60
sepsis 57
sepsis 57
hepatocellular carcinoma 56
depression 40
obesity 38
cardiovascular disease 38
carcinogenesis 36
hyperglycemia 36
Parkinson's disease 34
more...
Symptom
pain 45
hyperoxia 25
anesthesia 21
seizures 19
starvation 8
functional recovery 8
hypothermia 7
respiratory distress 6
hypercapnia 6
erythema 5
collapse 5
vomiting 4
tremor 4
weakness 4
exhaustion 3
diarrhea 3
splenomegaly 3
acute stress 3
skin damage 3
acute pain 3
more...
Drug
Heme 332
ROS 59
ALA 47
ascorbate 38
CoCl2 27
CoCl2 27
NADH 25
vitamin E 19
IFN-gamma 16
Dermatol 13
lysine 13
FAD 12
Cardiovasc 12
Glutathione 11
MAP 10
CSF 9
Angiotensin II 9
Arsenic trioxide 8
ICI 7
Nitric Oxide 7
more...
Enzyme
heme oxygenase 4196
superoxide dismutase 340
catalase 247
mitogen-activated protein kinase 205
NQO1 152
glutathione peroxidase 150
ALA synthase 138
guanylate cyclase 126
NO synthase 116
biliverdin reductase 101
caspase-3 101
protein kinase 93
peroxidase 90
glutathione S-transferase 69
alanine aminotransferase 64
gamma-glutamylcysteine synthetase 57
NADPH oxidase 56
glutathione reductase 54
luciferase 54
lactate dehydrogenase 54
more...
Compound
CO2 831
oxygen 792
iron 612
nitric oxide 456
Heme 361
zinc 305
Dec 293
tin 283
DNA 239
GSH 218
GSH 218
hydrogen 181
sodium 174
water 172
TNF 160
cobalt 148
cGMP 145
arginine 137
NADPH 134
NADPH 133
more...