Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.16.2 (tyrosine hydroxylase)
14,760 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
tyrosine hydroxylase 0.950
TH protein 0.015
tyrosine 3-monooxygenase 0.007
dopa decarboxylase 0.007
dopamine beta-hydroxylase 0.006
dopamine transporter 0.006
phenylethanolamine N-methyltransferase 0.005
neuropeptide Y 0.003
vesicular monoamine transporter 2 0.003
choline acetyltransferase 0.003
tryptophan hydroxylase 0.003
Nurr1 0.003
glial cell line-derived neurotrophic factor 0.002
substance P 0.001
calbindin 0.001
glutamic acid decarboxylase 0.001
galanin 0.001
GTP cyclohydrolase I 0.001
calretinin 0.001
vesicular acetylcholine transporter 0.001
NSD 0.001
glial fibrillary acidic protein 0.001
calcitonin 0.001
MPP 0.001
Phenylethanolamine N-methyltransferase 0.001
PGP 9.5 0.001
phenylalanine hydroxylase 0.001
synuclein 0.001
DA transporter 0.001
vasoactive intestinal peptide 0.001
olfactory 0.001
alpha-synuclein 0.001
nerve growth factor 0.000
GCH 0.000
neurotrophic factor 0.000
VMAT2 0.000
dopa-responsive dystonia 0.000
DARPP-32 0.000
A14 0.000
glutamate decarboxylase 0.000
vesicular glutamate transporter 2 0.000
norepinephrine transporter 0.000
PNMT 0.000
vasoactive intestinal peptide (VIP) 0.000
somatostatin 0.000
parvalbumin 0.000
brain-derived neurotrophic factor 0.000
neuronal nitric oxide synthase 0.000
A431 0.000
Neuropeptide Y 0.000
nitric oxide synthase 0.000
axonal 0.000
E14 0.000
neurotensin 0.000
DAT 0.000
A15 0.000
dynorphin 0.000
A11 0.000
GABA 0.000
Phox2b 0.000
MAO-B 0.000
tryptophan 5-monooxygenase 0.000
amino acid hydroxylase 0.000
tryptophan hydroxylase 2 0.000
GAD67 0.000
methyltransferase 0.000
acetylcholinesterase 0.000
sepiapterin reductase 0.000
synaptophysin 0.000
PNMT protein 0.000
dihydropteridine reductase 0.000
paired-like homeodomain transcription factor 3 0.000
Leu-enkephalin 0.000
proenkephalin 0.000
GDNF 0.000
neuron-specific enolase 0.000
neurturin 0.000
PITX3 0.000
cholecystokinin 0.000
NURR1 0.000
more...
Disease
Parkinson's disease 0.008
NSD 0.001
parkinsonism 0.001
varices 0.000
pheochromocytoma 0.000
neuroblastoma 0.000
DRD 0.000
Abnormal chorionic villi 0.000
hemiparkinsonism 0.000
DYT14 0.000
akinesia 0.000
Congenital aqueductal stenosis 0.000
Sympathetic paraganglioma 0.000
Sensory neglect 0.000
Carotid body 0.000
Carotid body 0.000
Carotid body 0.000
abnormal involuntary movements 0.000
catalepsy 0.000
SCH 0.000
Peripheral neuroblastoma 0.000
Supranuclear ophthalmoplegia 0.000
movement disorder 0.000
DYT4 0.000
schizophrenia 0.000
DYT2 0.000
hyperphenylalaninemia 0.000
GAD 0.000
drug addiction 0.000
GTP cyclohydrolase I deficiency 0.000
dyskinesia 0.000
Alzheimer's disease 0.000
Chronic hypernatremia 0.000
amphetamine psychosis 0.000
Food hoarding 0.000
hyperprolactinemia 0.000
ASMD 0.000
DYT7 0.000
Dementia with Lewy bodies 0.000
Morphine dependence 0.000
JPD 0.000
DSAP 0.000
depression 0.000
Neuroblastoma 0.000
Neuroblastoma 0.000
PARK10 0.000
Juvenile Parkinsonism 0.000
Neonatal hyperthyroidism 0.000
Chronic hypotension 0.000
Equine grass sickness 0.000
addiction 0.000
Olfactory nerve 0.000
Huntington's disease 0.000
PARK7 0.000
LI3 0.000
neoplasm of uncertain malignant potential 0.000
Amphetamine withdrawal 0.000
DYT11 0.000
PARK4 0.000
Iron deficiency without anemia 0.000
PARK3 0.000
torsion dystonia 0.000
PCBD 0.000
Succinic semialdehyde dehydrogenase deficiency 0.000
Evans 0.000
hypertension 0.000
cholera 0.000
DYT1 0.000
glycopenia 0.000
phenylketonuria 0.000
GSH 0.000
cold 0.000
Neuroaxonal dystrophy 0.000
social stress 0.000
bipolar disorder 0.000
Pineal 0.000
Manganese deficiency 0.000
Basal ganglia calcification 0.000
cocaine addiction 0.000
IDDM2 0.000
more...
Symptom
bradykinesia 0.000
dystonia 0.000
functional recovery 0.000
POA 0.000
Lightening 0.000
tremor 0.000
acute stress 0.000
Circling 0.000
impaired motor coordination 0.000
Stepping 0.000
Motor dysfunction 0.000
Postural tremor 0.000
Deafferentation 0.000
muscle rigidity 0.000
Rest tremor 0.000
pain 0.000
hypercapnia 0.000
abnormal gait 0.000
motor symptom 0.000
Excitability 0.000
No toxic effect 0.000
Behavioral symptoms 0.000
chorea 0.000
despair 0.000
cardiovascular impairment 0.000
seizures 0.000
ataxia 0.000
loss of equilibrium 0.000
hypothermia 0.000
pachyonychia 0.000
adipsia 0.000
aphagia 0.000
incoordination 0.000
loss of balance 0.000
fasciculation 0.000
abnormal breathing 0.000
neurological disability 0.000
ACHE 0.000
constipation 0.000
excessive sweating 0.000
hyperoxia 0.000
athetosis 0.000
myoclonus 0.000
anesthesia 0.000
analgesia 0.000
intention tremor 0.000
hunger 0.000
thinning 0.000
syncope 0.000
hypersomnia 0.000
catatonia 0.000
Decreased activity 0.000
ataxic gait 0.000
starvation 0.000
hypotonia 0.000
anosmia 0.000
anorexia 0.000
torticollis 0.000
neuralgia 0.000
colic 0.000
general problem 0.000
twitching 0.000
DNA marker 0.000
orofacial pain 0.000
agitation 0.000
masculinization 0.000
chronic constipation 0.000
tonic-clonic seizure 0.000
cachexia 0.000
Neuropathic pain 0.000
lethargy 0.000
ophthalmoplegia 0.000
physical appearance 0.000
photophobia 0.000
cerebellar ataxia 0.000
acute pain 0.000
sleepiness 0.000
fatigue 0.000
exhaustion 0.000
flank pain 0.000
more...
Drug
BH4 0.001
L-tyrosine 0.001
Reserpine 0.000
HCH 0.000
Apomorphine 0.000
3,4-Dihydroxyphenylalanine 0.000
Liver hydrolysate 0.000
Pramipexole 0.000
Pramipexole 0.000
Nephron 0.000
Brocresine 0.000
p75 0.000
Bupleurum root 0.000
Pitressin tannate 0.000
Forskolin 0.000
Ipecac syrup 0.000
7-Nitroindazole 0.000
Uncaria hook 0.000
Ddc 0.000
Parkin 0.000
Parkin 0.000
Doca 0.000
Madopar 0.000
EPL 0.000
Guanethidine 0.000
nitroglycerin 0.000
Pentolinium 0.000
Secretin 0.000
Sinemet 0.000
Benserazide 0.000
Lergotrile 0.000
Deferoxamine mesylate 0.000
Sinemet 0.000
Fluspirilene 0.000
Betoptic 0.000
DHT 0.000
Tirilazad mesylate 0.000
Fidarestat 0.000
Fidarestat 0.000
DHT 0.000
9-THC 0.000
Zonisamide 0.000
Tirilazad mesylate 0.000
Betoptic 0.000
Manganese chloride 0.000
Nitisinone 0.000
Sinemet 0.000
Eldepryl 0.000
Clonidine 0.000
Rasagiline 0.000
Carbidopa 0.000
Azilect 0.000
Angiotensin II 0.000
Pitressin 0.000
GHRP 0.000
Epalrestat 0.000
Mazindol 0.000
Safflower 0.000
Tianma 0.000
Nisoxetine 0.000
Retinoic acid 0.000
Lisuride 0.000
Modafinil 0.000
KAN 0.000
Desferal 0.000
Sesame oil 0.000
Kainic acid 0.000
Pimobendan 0.000
Ethanol 0.000
Ritanserin 0.000
Remoxipride 0.000
EE2 0.000
Histamine 0.000
Atomoxetine 0.000
Valproic Acid 0.000
CSF 0.000
Sulpiride 0.000
Rotigotine 0.000
caffeine 0.000
Cilostazol 0.000
more...
Enzyme
tyrosine hydroxylase 1.000
dopamine beta-hydroxylase 0.007
phenylethanolamine N-methyltransferase 0.005
tryptophan hydroxylase 0.003
aromatic L-amino acid decarboxylase 0.003
choline acetyltransferase 0.003
DOPA decarboxylase 0.003
GTP cyclohydrolase I 0.001
MPP 0.001
phenylalanine hydroxylase 0.001
monoamine oxidase 0.000
glutamate decarboxylase 0.000
NADPH-diaphorase 0.000
DAT 0.000
cyclohydrolase 0.000
sepiapterin reductase 0.000
acetylcholinesterase 0.000
protein kinase 0.000
dihydropteridine reductase 0.000
phenol oxidase 0.000
tyrosinase 0.000
EC 2.1.1.29 0.000
6-pyruvoyltetrahydropterin synthase 0.000
pterin-4alpha-carbinolamine dehydratase 0.000
peroxidase 0.000
diaphorase 0.000
NO synthase 0.000
caspase-3 0.000
NQO1 0.000
mitogen-activated protein kinase 0.000
adenylate cyclase 0.000
protein kinase C 0.000
aspartate 1-decarboxylase 0.000
complex I 0.000
tyrosine decarboxylase 0.000
catechol O-methyltransferase 0.000
enolase 0.000
diaphorase 0.000
AMPK 0.000
CaMKII 0.000
2',3'-cyclic nucleotide phosphohydrolase 0.000
NOS 0.000
superoxide dismutase 0.000
amine N-methyltransferase 0.000
retinol saturase 0.000
proprotein convertase 2 0.000
DCF 0.000
histidine decarboxylase 0.000
GABA transaminase 0.000
chloramphenicol acetyltransferase 0.000
NADPH oxidase 0.000
NADPH oxidase 0.000
alkylglycerol monooxygenase 0.000
beta-galactosidase 0.000
catalase 0.000
alkene monooxygenase 0.000
phosphodiesterase 0.000
calcineurin 0.000
guanylate cyclase 0.000
arylalkylamine N-acetyltransferase 0.000
catechol oxidase 0.000
neurosin 0.000
MT 1 0.000
GSK 0.000
glutathione peroxidase 0.000
glutamine synthetase 0.000
ERK 0.000
CNPase 0.000
proteasome 0.000
lactate dehydrogenase 0.000
luciferase 0.000
protein phosphatase 2A 0.000
aldehyde dehydrogenase 0.000
aldehyde dehydrogenase 0.000
aldehyde dehydrogenase 0.000
decarbonylase 0.000
tyrosylprotein sulfotransferase 0.000
aldehyde dehydrogenase 0.000
cathepsin X 0.000
STK 0.000
more...
Compound
MPTP 0.010
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 0.008
L-DOPA 0.004
Dopamine 0.001
Dopa 0.001
noradrenaline 0.001
3,4-dihydroxyphenylalanine 0.001
MPP 0.001
MPP 0.001
DOPAC 0.001
6-methyltetrahydropterin 0.001
DBH 0.001
tyrosine 0.001
6-Hydroxydopamine 0.000
Methamphetamine 0.000
4-phenyl-1,2,3,6-tetrahydropyridine 0.000
5-HT 0.000
Rotenone 0.000
6R-BH4 0.000
DAT 0.000
GABA 0.000
GABA 0.000
HVA 0.000
gamma-aminobutyric acid 0.000
MPT 0.000
pteridine 0.000
H 44/68 0.000
Norepinephrine 0.000
Tetrahydrobiopterin 0.000
Gepefrine 0.000
glutamate 0.000
1,2,3,6-tetrahydropyridine 0.000
1,2,3,6-tetrahydropyridine 0.000
cAMP 0.000
Substance P 0.000
Phenylethanolamine 0.000
Adrenal 0.000
AMP 0.000
hydroxyindoleacetic acid 0.000
Neuronal 0.000
1-methyl-1,2,3,6-tetrahydropyridine 0.000
1-benzyl-1,2,3,4-tetrahydroisoquinoline 0.000
Tetrahydroneopterin 0.000
Biopterin 0.000
Pargyline 0.000
Reserpine 0.000
5-hydroxytryptophan 0.000
Metyrosine 0.000
1-Methyl-4-phenylpyridinium 0.000
C9H17NO2 0.000
DOPA sulfate 0.000
calcium 0.000
6,7-dimethyl-5,6,7,8-tetrahydropteridine 0.000
DDC 0.000
DDC 0.000
Dopaquinone 0.000
C9H17NO2 0.000
1,2,3,4-tetrahydroisoquinoline 0.000
Amphetamine 0.000
Amphetamine 0.000
nitric oxide 0.000
fluorine 0.000
Dec 0.000
Anonaine 0.000
Cephaeline 0.000
Coronal 0.000
Selegiline 0.000
Nicotine 0.000
retinoic acid 0.000
oxygen 0.000
Molindone 0.000
3-O-Methyldopa 0.000
Haloperidol 0.000
silver 0.000
3-Chlorotyrosine 0.000
Haloperidol 0.000
Paraquat 0.000
3-hydroxyphenylethylamine 0.000
D-Tyrosine 0.000
4-(2-aminoethyl)phenol 0.000
more...