Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.16.2 (tyrosine hydroxylase)
 14,760 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
transmembrane protein 195 11.1
KIAA1024L 11.1
tyrosine hydroxylase isoform 2 11.1
CDP2 11.1
tyrosine hydroxylase 11.0
tyrosine 3-monooxygenase 11.0
TH protein 10.7
PTPRO protein 10.1
ARHGAP10 protein 10.1
tyrosinase precursor 10.1
protein kinase C alpha type 10.1
AMPA 3 10.1
UBX domain protein 11 10.1
paired-like homeodomain transcription factor 3 9.9
phenylethanolamine N-methyltransferase 9.6
potassium channel 2 9.5
tyrosine hydroxylase isoform 1 9.5
fibronectin leucine rich transmembrane protein 3 9.5
VIP2R 9.5
TPH1 protein 9.5
Transforming growth factor-beta 3 9.5
PNMT protein 9.4
Nurr1 9.1
CDIPT 9.1
amino acid hydroxylase 9.1
ubiquitin specific peptidase 24 9.1
sonic hedgehog homolog 9.1
neurexophilin 3 9.1
Phenylethanolamine N-methyltransferase 9.1
tryptophan 5-monooxygenase 9.0
dopamine beta-hydroxylase 8.9
vesicular monoamine transporter 2 8.9
dopa decarboxylase 8.9
JPD 8.8
GABAA receptor alpha5 8.8
SLC35D3 8.8
engrailed homeobox 1 8.8
dopamine and cAMP-regulated phosphoprotein of 32 kDa 8.7
GTP cyclohydrolase I 8.5
GCH 8.5
RGS-PX1 8.5
FMO 1 8.5
TAFA5 8.5
Cadherin-8 8.5
RGS9 protein 8.5
LIM homeobox transcription factor 1 alpha 8.5
tryptophan hydroxylase 8.5
PITX3 8.4
PNMT 8.4
phenylalanine 4-monooxygenase 8.4
myelin transcription factor 1-like 8.3
NT5DC2 8.3
GIN1 8.3
6-pyruvoyltetrahydropterin synthase 8.3
H2A.X protein 8.3
helix-loop-helix zipper protein 8.3
dopamine transporter 8.2
dopa-responsive dystonia 8.2
glial cell derived neurotrophic factor 8.2
VMAT2 8.2
vesicular acetylcholine transporter 8.1
conserved dopamine neurotrophic factor 8.1
NSD 8.1
PCD17 8.1
TRPM2 protein 8.1
PER1 protein 8.1
NELL2 protein 8.1
GCH1 protein 8.1
BTB domain protein 8.1
HBGR2 8.1
PP35 8.1
heterogeneous nuclear ribonucleoprotein A3 8.1
NURR1 8.0
Hsp70 interacting protein 8.0
vesicular glutamate transporter 2 8.0
MEF2D protein 7.9
Phenylalanine hydroxylase 7.9
acyl coenzyme A binding protein 7.9
DDC protein 7.9
Oligo2 7.9
more...
Disease
Abnormal chorionic villi 11.1
Congenital aqueductal stenosis 10.1
Sensory neglect 10.1
Sympathetic paraganglioma 10.1
DYT14 9.5
Supranuclear ophthalmoplegia 9.5
Peripheral neuroblastoma 9.5
DYT4 8.6
DYT2 8.4
Chronic hypernatremia 8.3
NSD 8.3
GTP cyclohydrolase I deficiency 8.1
ASMD 7.9
DRD 7.9
Food hoarding 7.8
JPD 7.8
Juvenile Parkinsonism 7.6
PARK10 7.6
DYT7 7.6
Chronic hypotension 7.5
hemiparkinsonism 7.4
DSAP 7.4
Equine grass sickness 7.4
Carotid body 7.3
Carotid body 7.3
Carotid body 7.3
amphetamine psychosis 7.3
Neonatal hyperthyroidism 7.3
neoplasm of uncertain malignant potential 7.2
LI3 7.2
Amphetamine withdrawal 7.2
Morphine dependence 7.1
PARK4 7.1
Olfactory nerve 7.0
Iron deficiency without anemia 7.0
PARK3 7.0
PCBD 6.9
Succinic semialdehyde dehydrogenase deficiency 6.8
DYT11 6.8
glycopenia 6.7
Parkinson's disease 6.6
Neuroaxonal dystrophy 6.5
abnormal involuntary movements 6.3
Manganese deficiency 6.3
Basal ganglia calcification 6.2
hyperphenylalaninemia 6.0
HPNS 5.9
IDDM2 5.9
Pure autonomic failure 5.9
PARK7 5.8
demineralization of bone 5.8
Insulin hypoglycemia 5.7
parkinsonism 5.7
PARK1 5.7
borderline mental retardation 5.7
metastatic pheochromocytoma 5.6
varices 5.5
akinesia 5.5
disorders of iron metabolism 5.4
Argininosuccinic aciduria 5.4
Gastric perforation 5.4
pulmonary carcinoid tumor 5.4
OBX 5.4
Stereotypy 5.4
torsion dystonia 5.3
catalepsy 5.3
neurogenic hypertension 5.3
Teratocarcinoma 5.3
DYT1 5.3
Congenital central hypoventilation syndrome 5.3
psychoactive substance abuse 5.3
Cardiac autonomic neuropathy 5.2
XDP 5.1
pheochromocytoma 5.1
ED3 5.0
Globus 5.0
metastatic neuroblastoma 5.0
GAD 5.0
Abnormal behavior 5.0
LDD 5.0
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Symptom
Lightening 7.5
Circling 6.1
Postural tremor 5.9
bradykinesia 5.9
POA 5.8
Motor dysfunction 5.7
impaired motor coordination 5.5
Rest tremor 5.3
Deafferentation 5.3
Stepping 5.2
No toxic effect 4.7
Behavioral symptoms 4.7
dystonia 4.5
Excitability 4.3
cardiovascular impairment 4.3
motor symptom 4.2
muscle rigidity 4.2
functional recovery 4.0
loss of equilibrium 3.9
acute stress 3.9
abnormal gait 3.7
pachyonychia 3.6
adipsia 3.5
aphagia 3.5
abnormal breathing 3.3
loss of balance 3.3
despair 3.2
chorea 3.2
ACHE 3.2
athetosis 3.0
tremor 3.0
excessive sweating 2.9
neurological disability 2.8
fasciculation 2.7
intention tremor 2.6
incoordination 2.6
hypercapnia 2.6
hypersomnia 2.0
Decreased activity 2.0
ataxic gait 2.0
catatonia 2.0
myoclonus 1.8
hyperoxia 1.7
ataxia 1.5
anosmia 1.5
torticollis 1.4
hunger 1.4
constipation 1.3
general problem 1.3
neuralgia 1.3
hypothermia 1.2
DNA marker 1.2
orofacial pain 1.2
twitching 1.1
colic 1.0
thinning 0.9
syncope 0.9
hypotonia 0.9
masculinization 0.8
chronic constipation 0.7
tonic-clonic seizure 0.7
Neuropathic pain 0.6
seizures 0.5
physical appearance 0.5
photophobia 0.4
analgesia 0.4
ophthalmoplegia 0.4
anorexia 0.3
cerebellar ataxia 0.3
cachexia 0.2
lethargy 0.2
acute pain 0.1
pain 0.1
agitation 0.1
starvation 0.1
flank pain -0.0
polydipsia -0.0
pallor -0.2
tachypnea -0.2
dry eye -0.3
more...
Drug
Liver hydrolysate 10.1
Brocresine 8.5
3,4-Dihydroxyphenylalanine 8.1
Bupleurum root 7.9
Pitressin tannate 7.9
Ipecac syrup 7.5
BH4 7.4
Uncaria hook 7.3
Doca 7.2
L-tyrosine 7.0
Pramipexole 6.9
Pramipexole 6.8
Pentolinium 6.6
7-Nitroindazole 6.6
Lergotrile 6.6
Deferoxamine mesylate 6.6
Reserpine 6.5
Ddc 6.5
Fluspirilene 6.4
Betoptic 6.4
Tirilazad mesylate 6.3
Benserazide 6.3
Fidarestat 6.3
Fidarestat 6.3
Madopar 6.2
Apomorphine 6.2
Tirilazad mesylate 6.2
Betoptic 6.2
Nitisinone 6.1
Manganese chloride 6.1
EPL 6.0
Eldepryl 6.0
Azilect 5.8
Sinemet 5.6
Guanethidine 5.6
HCH 5.6
Sinemet 5.5
Epalrestat 5.5
Rasagiline 5.4
Tianma 5.3
Carbidopa 5.3
Nisoxetine 5.3
Mazindol 5.2
Safflower 5.1
Zonisamide 5.1
Pitressin 5.0
Lisuride 5.0
Sesame oil 5.0
KAN 4.9
Pimobendan 4.9
Secretin 4.9
Sinemet 4.8
Remoxipride 4.7
Ritanserin 4.6
Desferal 4.6
Valproic Acid 4.5
Parkin 4.5
Parkin 4.5
Forskolin 4.5
GHRP 4.5
Modafinil 4.5
Rotigotine 4.4
Atomoxetine 4.4
p75 4.4
Cinnarizine 4.3
Flupenthixol 4.2
Fluphenazine 4.2
Thioridazine 4.2
Idebenone 4.1
9-THC 4.1
Dexfenfluramine 4.1
Desferal 4.1
Kainic acid 4.1
Hyperforin 4.0
DHT 4.0
Vandetanib 4.0
Cilostazol 4.0
DHT 4.0
Rolipram 3.9
Sulpiride 3.9
more...
Enzyme
EC 2.1.1.29 11.1
tyrosine hydroxylase 11.1
phenylethanolamine N-methyltransferase 9.6
aromatic L-amino acid decarboxylase 9.3
dopamine beta-hydroxylase 9.2
pterin-4alpha-carbinolamine dehydratase 9.1
DOPA decarboxylase 8.7
tryptophan hydroxylase 8.5
GTP cyclohydrolase I 8.5
6-pyruvoyltetrahydropterin synthase 8.3
aspartate 1-decarboxylase 8.3
sepiapterin reductase 7.9
choline acetyltransferase 7.5
amine N-methyltransferase 7.5
phenylalanine hydroxylase 7.5
retinol saturase 7.4
cyclohydrolase 7.4
2',3'-cyclic nucleotide phosphohydrolase 7.3
proprotein convertase 2 7.3
MPP 7.3
dihydropteridine reductase 7.1
glutamate decarboxylase 6.8
tyrosine decarboxylase 6.7
DAT 6.6
phenol oxidase 6.5
alkylglycerol monooxygenase 6.5
alkene monooxygenase 6.4
catechol O-methyltransferase 6.2
NADPH-diaphorase 6.0
neurosin 6.0
MT 1 5.9
monoamine oxidase 5.8
catechol oxidase 5.6
decarbonylase 5.3
diaphorase 5.3
tyrosylprotein sulfotransferase 5.2
GABA transaminase 4.9
cathepsin X 4.9
STK 4.9
tyrosinase 4.8
arylalkylamine N-acetyltransferase 4.7
histidine decarboxylase 4.6
kynurenine aminotransferase 4.6
CNPase 4.6
enolase 4.6
aromatic amino acid aminotransferase 4.6
DCF 4.5
NQO1 4.5
succinic semialdehyde dehydrogenase 4.4
CaMKII 4.4
phosphatidylinositol synthase 4.4
glutaminyl cyclase 4.3
aspartylglucosaminidase 4.3
diaphorase 4.2
caspase-11 4.2
caspase-11 4.2
endo-N 4.2
LDT 4.2
acetylcholinesterase 4.1
complex I 4.1
NO synthase 4.0
PAT 3.9
isopeptidase 3.9
NOS 3.9
BBE 3.7
AMPK 3.7
guanylate kinase 3.6
chloramphenicol acetyltransferase 3.6
adenylate cyclase 3.6
kynurenine 3-monooxygenase 3.5
kynureninase 3.5
Lod 3.5
naphthalene dioxygenase 3.4
Thy1 3.4
protein kinase 3.3
protein phosphatase 2A 3.3
tyrosine aminotransferase 3.3
caspase-3 3.2
mu-calpain 3.2
caspase-6 3.2
more...
Compound
Gepefrine 10.5
Tetrahydroneopterin 10.1
H 44/68 9.6
6-methyltetrahydropterin 9.5
C9H17NO2 9.5
DOPA sulfate 9.5
Metyrosine 9.1
C9H17NO2 9.1
6R-BH4 8.9
6,7-dimethyl-5,6,7,8-tetrahydropteridine 8.8
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 8.7
Dopaquinone 8.6
MPTP 8.5
Anonaine 8.5
Cephaeline 8.5
1-methyl-1,2,3,6-tetrahydropyridine 8.4
1-benzyl-1,2,3,4-tetrahydroisoquinoline 8.4
Phenylethanolamine 8.3
4-phenyl-1,2,3,6-tetrahydropyridine 8.2
Biopterin 8.1
3-Chlorotyrosine 8.1
3,4-dihydroxyphenylalanine 8.0
6-Hydroxydopamine 8.0
D-Tyrosine 7.9
Molindone 7.9
4-(2-aminoethyl)phenol 7.9
3-O-Methyldopa 7.9
DBH 7.9
Dopa 7.8
Orobol 7.8
Amdro 7.6
7,8-Dihydrobiopterin 7.6
3-hydroxyphenylethylamine 7.6
1-Methyl-4-phenylpyridinium 7.6
1-methyl-3,4-dihydroisoquinoline 7.5
Bruceine D 7.5
1,2,3,6-tetrahydropyridine 7.5
1,2,3,6-tetrahydropyridine 7.5
MPP 7.4
4-methylphenylalanine 7.4
PC-4 7.4
BSSG 7.4
L-DOPA 7.3
MPP 7.3
Tetrahydrobiopterin 7.3
DOPAC 7.3
1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline 7.2
Rotenone 7.2
MPT 7.2
Pargyline 7.1
Bulbocapnine 7.1
Valerenic acid 7.0
Cyanazine 7.0
Iprindole 6.9
U-14,624 6.9
Methylazoxymethanol acetate 6.9
6-fluorotryptophan 6.9
pteridine 6.9
Methamphetamine 6.8
Dopamine 6.8
8-Bromoadenosine 6.7
8-Bromoadenosine 6.7
8-Bromoadenosine 6.7
8-Bromoadenosine 6.7
8-Bromoadenosine 6.7
8-Bromoadenosine 6.7
8-Bromoadenosine 6.7
Thiodiglycol 6.7
DAT 6.6
IPAS 6.6
m-hydroxyphenylacetic acid 6.6
Maneb 6.5
MMPR 6.5
HVA 6.4
MIF-I 6.4
DDC 6.4
DDC 6.4
Selegiline 6.4
Dihydralazine 6.4
Ginkgetin 6.3
more...