Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.14.16.2 (tyrosine hydroxylase)
14,760 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein tyrosine hydroxylase 14698 Sep 939 Mol 723 neuropeptide Y 692 substance P 677 dopamine transporter 607 choline acetyltransferase 535 olfactory 526 dopa decarboxylase 443 glial fibrillary acidic protein 441 dopamine beta-hydroxylase 436 calcitonin 435 axonal 395 polypeptide 333 nitric oxide synthase 326 GABA 318 somatostatin 312 calbindin 293 nerve growth factor 289 TH protein 287 tryptophan hydroxylase 278 brain-derived neurotrophic factor 253 glial cell line-derived neurotrophic factor 252 glutamic acid decarboxylase 243 peroxidase 242 prolactin 241 acetylcholinesterase 231 galanin 220 AMP 217 synuclein 217 vesicular monoamine transporter 2 215 phenylethanolamine N-methyltransferase 211 calretinin 200 vasoactive intestinal peptide 196 beta-endorphin 195 caspase-3 191 insulin 186 alpha-synuclein 178 neurotrophic factor 177 Nurr1 169 methyltransferase 166 5-hydroxytryptamine 165 ATP 150 parvalbumin 150 c-fos 149 cholecystokinin 149 A431 148 vasopressin 141 neuronal nitric oxide synthase 138 MPP 134 lipopolysaccharide 131 vasoactive intestinal peptide (VIP) 128 oxytocin 128 superoxide dismutase 125 neurotensin 124 synaptophysin 119 Bcl-2 118 tyrosinase 113 dynorphin 113 phenylalanine hydroxylase 111 gut 109 glutamate decarboxylase 106 tyrosine 3-monooxygenase 104 PGP 9.5 102 adenylate cyclase 101 vesicular acetylcholine transporter 96 ERK1 96 inducible nitric oxide synthase 96 E14 95 NSD 92 neuron-specific enolase 91 calmodulin 91 Neuropeptide Y 89 DA transporter 89 neurotrophin 84 tumor necrosis factor 84 MAO-B 84 corticotropin-releasing factor 83 ubiquitin 83 ACTH 83 more...

Disease Parkinson's disease 2796 parkinsonism 351 neuroblastoma 275 depression 237 varices 234 pheochromocytoma 232 Alzheimer's disease 222 schizophrenia 196 tumor 183 hypertension 178 cold 119 cancer 118 diabetes 100 NSD 92 addiction 84 obesity 79 GSH 78 ischemia 77 SCH 65 cholera 61 drug addiction 59 Huntington's disease 57 movement disorder 55 melanoma 54 dementia 51 dyskinesia 50 stroke 48 akinesia 48 Evans 47 catalepsy 45 bipolar disorder 44 aggression 43 hyperprolactinemia 41 herpes simplex 40 epilepsy 40 celiac disease 39 myocardial infarction 39 heart failure 39 GAD 37 hypoglycemia 37 cognitive impairment 34 uterus 33 ADHD 31 psychosis 30 NAME 28 SEM 28 neurological disease 27 Neuroblastoma 26 Neuroblastoma 26 autism 25 alcoholism 25 chronic pain 25 cerebral ischemia 24 type 2 diabetes 24 Dementia with Lewy bodies 23 ATM 23 abnormal involuntary movements 23 Pituitary 23 phenylketonuria 22 PHA 22 encephalopathy 22 hyperglycemia 22 suicide 22 memory impairment 21 SDS 21 major depressive disorder 21 amyotrophic lateral sclerosis 20 Brown 20 chronic renal failure 20 metastases 20 Pineal 20 sudden infant death syndrome 20 hypothyroidism 19 glioma 18 tumor growth 18 hyperphenylalaninemia 18 drug abuse 18 mental illness 18 social stress 18 urethra 17 more...

Symptom pain 131 functional recovery 99 dystonia 91 tremor 68 bradykinesia 63 seizures 53 anesthesia 36 acute stress 32 hypercapnia 22 ataxia 21 hypothermia 19 analgesia 17 POA 14 starvation 12 constipation 12 thinning 10 chorea 9 fatigue 9 muscle rigidity 9 syncope 8 anorexia 8 hyperoxia 8 myoclonus 7 hunger 7 abnormal gait 7 despair 7 agitation 6 collapse 6 vomiting 6 diarrhea 5 Stepping 5 hypotonia 5 incoordination 5 impaired motor coordination 4 exhaustion 4 sleepiness 4 motor symptom 4 headache 4 fasciculation 4 lethargy 3 colic 3 Excitability 3 neurological disability 3 Deafferentation 3 insomnia 3 distraction 3 cachexia 3 catatonia 2 cerebellar ataxia 2 Circling 2 neuralgia 2 ophthalmoplegia 2 anosmia 2 loss of balance 2 twitching 2 torticollis 2 hypersomnia 2 excessive sweating 2 back pain 2 masculinization 2 Motor dysfunction 2 nausea 2 weakness 2 spasticity 2 acute pain 2 polydipsia 1 aphagia 1 cardiovascular impairment 1 photophobia 1 nausea and vomiting 1 Neuropathic pain 1 spasm 1 physical appearance 1 general problem 1 Decreased activity 1 exertional dyspnea 1 cough 1 chronic constipation 1 dizziness 1 DNA marker 1 more...

Drug L-tyrosine 144 BH4 123 Nephron 106 HCH 76 Reserpine 43 Apomorphine 42 lysine 39 nitroglycerin 38 p75 37 CSF 35 caffeine 28 Forskolin 28 NADH 27 ascorbate 26 Dermatol 24 Ethanol 21 Angiotensin II 21 ROS 21 Parkin 20 MAP 20 Parkin 20 EE2 18 DHT 17 DHT 16 Histamine 15 Clonidine 15 Cardiovasc 15 Retinoic acid 14 9-THC 14 Gel 13 vitamin E 11 Pramipexole 11 Pramipexole 11 Secretin 10 3,4-Dihydroxyphenylalanine 10 Portal 10 ICI 10 ABC 9 ENT 9 Diurnal 7 Sinemet 7 PCP 7 Monit 7 Guanethidine 6 IFN-gamma 6 CaCl2 6 CaCl2 6 CTX 6 Glucagon 6 CaCl2 6 GHRP 6 Frontal 6 Zonisamide 6 ETS 5 Kainic acid 5 Activin 5 Doxycycline 5 Sinemet 5 Sinemet 5 IL-11 5 IL-2 5 Indomethacin 5 EPL 5 DNase I 5 Glutathione 5 Paraffin 5 Phentolamine 5 Atropine 5 Modafinil 4 Sulpiride 4 Estrogens 4 Heme 4 7-Nitroindazole 4 Pitressin 4 RFP 4 NBT 4 ETA 4 Ddc 4 Luteinizing 4 CAM 4 more...

Enzyme tyrosine hydroxylase 14760 choline acetyltransferase 538 protein kinase 384 dopamine beta-hydroxylase 379 tryptophan hydroxylase 294 monoamine oxidase 278 peroxidase 269 mitogen-activated protein kinase 250 acetylcholinesterase 228 phenylethanolamine N-methyltransferase 215 DOPA decarboxylase 203 protein kinase C 167 aromatic L-amino acid decarboxylase 158 caspase-3 157 superoxide dismutase 142 MPP 134 NADPH-diaphorase 119 tyrosinase 116 phenylalanine hydroxylase 115 NO synthase 115 glutamate decarboxylase 113 GTP cyclohydrolase I 108 adenylate cyclase 105 ERK 93 catalase 90 AMPK 74 complex I 69 DAT 68 NQO1 64 luciferase 53 diaphorase 51 phosphodiesterase 50 NOS 50 proteasome 50 lactate dehydrogenase 49 diaphorase 49 calcineurin 46 beta-galactosidase 46 glutathione peroxidase 45 renin 43 NADPH oxidase 42 enolase 41 CaMKII 40 reverse transcriptase 40 NADPH oxidase 39 phenol oxidase 36 cyclohydrolase 33 guanylate cyclase 32 MEK 30 chloramphenicol acetyltransferase 28 dihydropteridine reductase 26 GSK 25 ATPase 24 alkaline phosphatase 24 focal adhesion kinase 23 trypsin 23 glutamine synthetase 21 DCF 21 ACS 21 phospholipase C 20 sepiapterin reductase 20 succinate dehydrogenase 19 ornithine decarboxylase 18 RNase 18 cytochrome oxidase 18 RNase 18 cholinesterase 18 aldehyde dehydrogenase 17 glutathione reductase 17 caspase-9 17 aldehyde dehydrogenase 17 aldehyde dehydrogenase 17 histidine decarboxylase 17 aldehyde dehydrogenase 17 aldehyde dehydrogenase 17 RNA polymerase 16 AMP-activated protein kinase 15 phosphatidylinositol 3-kinase 14 protein phosphatase 2A 14 catechol O-methyltransferase 13 more...

Compound Dec 1076 tyrosine 878 MPTP 875 noradrenaline 765 L-DOPA 688 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 622 calcium 504 Dopamine 437 oxygen 410 5-HT 367 glutamate 360 DNA 327 GABA 327 GABA 323 cAMP 305 water 276 nitric oxide 234 AMP 222 gamma-aminobutyric acid 205 sodium 186 Dopa 181 iron 167 silver 160 ATP 150 phosphate 149 potassium 148 Clin 142 MPP 134 MPP 134 Phe 131 3,4-dihydroxyphenylalanine 130 DOPAC 129 ethanol 128 methionine 116 glucose 113 Neuronal 112 tryptophan 110 acetate 108 tryptophan 106 retinoic acid 105 Norepinephrine 105 tryptophan 104 tryptophan 104 Adrenal 101 fluorine 97 serine 93 Methamphetamine 90 leucine 83 GSH 82 GSH 82 arginine 80 DBH 76 ACTH 74 nicotinamide 70 HVA 69 Substance P 69 DAT 68 His 67 TNF 67 sulfate 66 hydroxyindoleacetic acid 66 Nicotine 66 salt 65 manganese 65 NMDA 62 hydrogen 59 Rotenone 55 5-hydroxytryptophan 54 NADPH 51 GTP 51 NADPH 50 formaldehyde 48 cysteine 48 zinc 48 nitrogen 47 lysine 46 formaldehyde 44 alanine 44 cGMP 43 Reserpine 43 more...

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