Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.14.16.2 (
tyrosine hydroxylase
)
14,760
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
tyrosine hydroxylase
14698
Sep
939
Mol
723
neuropeptide Y
692
substance P
677
dopamine transporter
607
choline acetyltransferase
535
olfactory
526
dopa decarboxylase
443
glial fibrillary acidic protein
441
dopamine beta-hydroxylase
436
calcitonin
435
axonal
395
polypeptide
333
nitric oxide synthase
326
GABA
318
somatostatin
312
calbindin
293
nerve growth factor
289
TH protein
287
tryptophan hydroxylase
278
brain-derived neurotrophic factor
253
glial cell line-derived neurotrophic factor
252
glutamic acid decarboxylase
243
peroxidase
242
prolactin
241
acetylcholinesterase
231
galanin
220
synuclein
217
AMP
217
vesicular monoamine transporter 2
215
phenylethanolamine N-methyltransferase
211
calretinin
200
vasoactive intestinal peptide
196
beta-endorphin
195
caspase-3
191
insulin
186
alpha-synuclein
178
neurotrophic factor
177
Nurr1
169
more...
Disease
Parkinson's disease
2796
parkinsonism
351
neuroblastoma
275
depression
237
varices
234
pheochromocytoma
232
Alzheimer's disease
222
schizophrenia
196
tumor
183
hypertension
178
cold
119
cancer
118
diabetes
100
NSD
92
addiction
84
obesity
79
GSH
78
ischemia
77
SCH
65
cholera
61
drug addiction
59
Huntington's disease
57
movement disorder
55
melanoma
54
dementia
51
dyskinesia
50
stroke
48
akinesia
48
Evans
47
catalepsy
45
bipolar disorder
44
aggression
43
hyperprolactinemia
41
epilepsy
40
herpes simplex
40
heart failure
39
celiac disease
39
myocardial infarction
39
hypoglycemia
37
GAD
37
more...
Symptom
pain
131
functional recovery
99
dystonia
91
tremor
68
bradykinesia
63
seizures
53
anesthesia
36
acute stress
32
hypercapnia
22
ataxia
21
hypothermia
19
analgesia
17
POA
14
constipation
12
starvation
12
thinning
10
fatigue
9
muscle rigidity
9
chorea
9
hyperoxia
8
anorexia
8
syncope
8
abnormal gait
7
myoclonus
7
hunger
7
despair
7
vomiting
6
collapse
6
agitation
6
Stepping
5
diarrhea
5
hypotonia
5
incoordination
5
impaired motor coordination
4
fasciculation
4
exhaustion
4
headache
4
motor symptom
4
sleepiness
4
cachexia
3
more...
Drug
L-tyrosine
144
BH4
123
Nephron
106
HCH
76
Reserpine
43
Apomorphine
42
lysine
39
nitroglycerin
38
p75
37
CSF
35
Forskolin
28
caffeine
28
NADH
27
ascorbate
26
Dermatol
24
ROS
21
Ethanol
21
Angiotensin II
21
Parkin
20
Parkin
20
MAP
20
EE2
18
DHT
17
DHT
16
Cardiovasc
15
Clonidine
15
Histamine
15
Retinoic acid
14
9-THC
14
Gel
13
Pramipexole
11
Pramipexole
11
vitamin E
11
Portal
10
Secretin
10
ICI
10
3,4-Dihydroxyphenylalanine
10
ABC
9
ENT
9
Diurnal
7
more...
Enzyme
tyrosine hydroxylase
14760
choline acetyltransferase
538
protein kinase
384
dopamine beta-hydroxylase
379
tryptophan hydroxylase
294
monoamine oxidase
278
peroxidase
269
mitogen-activated protein kinase
250
acetylcholinesterase
228
phenylethanolamine N-methyltransferase
215
DOPA decarboxylase
203
protein kinase C
167
aromatic L-amino acid decarboxylase
158
caspase-3
157
superoxide dismutase
142
MPP
134
NADPH-diaphorase
119
tyrosinase
116
NO synthase
115
phenylalanine hydroxylase
115
glutamate decarboxylase
113
GTP cyclohydrolase I
108
adenylate cyclase
105
ERK
93
catalase
90
AMPK
74
complex I
69
DAT
68
NQO1
64
luciferase
53
diaphorase
51
NOS
50
proteasome
50
phosphodiesterase
50
diaphorase
49
lactate dehydrogenase
49
beta-galactosidase
46
calcineurin
46
glutathione peroxidase
45
renin
43
more...
Compound
Dec
1076
tyrosine
878
MPTP
875
noradrenaline
765
L-DOPA
688
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
622
calcium
504
Dopamine
437
oxygen
410
5-HT
367
glutamate
360
GABA
327
DNA
327
GABA
323
cAMP
305
water
276
nitric oxide
234
AMP
222
gamma-aminobutyric acid
205
sodium
186
Dopa
181
iron
167
silver
160
ATP
150
phosphate
149
potassium
148
Clin
142
MPP
134
MPP
134
Phe
131
3,4-dihydroxyphenylalanine
130
DOPAC
129
ethanol
128
methionine
116
glucose
113
Neuronal
112
tryptophan
110
acetate
108
tryptophan
106
Norepinephrine
105
more...