Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.16.2 (tyrosine hydroxylase)
14,760 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
tyrosine hydroxylase 14698
Sep 939
Mol 723
neuropeptide Y 692
substance P 677
dopamine transporter 607
choline acetyltransferase 535
olfactory 526
dopa decarboxylase 443
glial fibrillary acidic protein 441
dopamine beta-hydroxylase 436
calcitonin 435
axonal 395
polypeptide 333
nitric oxide synthase 326
GABA 318
somatostatin 312
calbindin 293
nerve growth factor 289
TH protein 287
tryptophan hydroxylase 278
brain-derived neurotrophic factor 253
glial cell line-derived neurotrophic factor 252
glutamic acid decarboxylase 243
peroxidase 242
prolactin 241
acetylcholinesterase 231
galanin 220
synuclein 217
AMP 217
vesicular monoamine transporter 2 215
phenylethanolamine N-methyltransferase 211
calretinin 200
vasoactive intestinal peptide 196
beta-endorphin 195
caspase-3 191
insulin 186
alpha-synuclein 178
neurotrophic factor 177
Nurr1 169
more...
Disease
Parkinson's disease 2796
parkinsonism 351
neuroblastoma 275
depression 237
varices 234
pheochromocytoma 232
Alzheimer's disease 222
schizophrenia 196
tumor 183
hypertension 178
cold 119
cancer 118
diabetes 100
NSD 92
addiction 84
obesity 79
GSH 78
ischemia 77
SCH 65
cholera 61
drug addiction 59
Huntington's disease 57
movement disorder 55
melanoma 54
dementia 51
dyskinesia 50
stroke 48
akinesia 48
Evans 47
catalepsy 45
bipolar disorder 44
aggression 43
hyperprolactinemia 41
epilepsy 40
herpes simplex 40
heart failure 39
celiac disease 39
myocardial infarction 39
hypoglycemia 37
GAD 37
more...
Symptom
pain 131
functional recovery 99
dystonia 91
tremor 68
bradykinesia 63
seizures 53
anesthesia 36
acute stress 32
hypercapnia 22
ataxia 21
hypothermia 19
analgesia 17
POA 14
constipation 12
starvation 12
thinning 10
fatigue 9
muscle rigidity 9
chorea 9
hyperoxia 8
anorexia 8
syncope 8
abnormal gait 7
myoclonus 7
hunger 7
despair 7
vomiting 6
collapse 6
agitation 6
Stepping 5
diarrhea 5
hypotonia 5
incoordination 5
impaired motor coordination 4
fasciculation 4
exhaustion 4
headache 4
motor symptom 4
sleepiness 4
cachexia 3
more...
Drug
L-tyrosine 144
BH4 123
Nephron 106
HCH 76
Reserpine 43
Apomorphine 42
lysine 39
nitroglycerin 38
p75 37
CSF 35
Forskolin 28
caffeine 28
NADH 27
ascorbate 26
Dermatol 24
ROS 21
Ethanol 21
Angiotensin II 21
Parkin 20
Parkin 20
MAP 20
EE2 18
DHT 17
DHT 16
Cardiovasc 15
Clonidine 15
Histamine 15
Retinoic acid 14
9-THC 14
Gel 13
Pramipexole 11
Pramipexole 11
vitamin E 11
Portal 10
Secretin 10
ICI 10
3,4-Dihydroxyphenylalanine 10
ABC 9
ENT 9
Diurnal 7
more...
Enzyme
tyrosine hydroxylase 14760
choline acetyltransferase 538
protein kinase 384
dopamine beta-hydroxylase 379
tryptophan hydroxylase 294
monoamine oxidase 278
peroxidase 269
mitogen-activated protein kinase 250
acetylcholinesterase 228
phenylethanolamine N-methyltransferase 215
DOPA decarboxylase 203
protein kinase C 167
aromatic L-amino acid decarboxylase 158
caspase-3 157
superoxide dismutase 142
MPP 134
NADPH-diaphorase 119
tyrosinase 116
NO synthase 115
phenylalanine hydroxylase 115
glutamate decarboxylase 113
GTP cyclohydrolase I 108
adenylate cyclase 105
ERK 93
catalase 90
AMPK 74
complex I 69
DAT 68
NQO1 64
luciferase 53
diaphorase 51
NOS 50
proteasome 50
phosphodiesterase 50
diaphorase 49
lactate dehydrogenase 49
beta-galactosidase 46
calcineurin 46
glutathione peroxidase 45
renin 43
more...
Compound
Dec 1076
tyrosine 878
MPTP 875
noradrenaline 765
L-DOPA 688
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 622
calcium 504
Dopamine 437
oxygen 410
5-HT 367
glutamate 360
GABA 327
DNA 327
GABA 323
cAMP 305
water 276
nitric oxide 234
AMP 222
gamma-aminobutyric acid 205
sodium 186
Dopa 181
iron 167
silver 160
ATP 150
phosphate 149
potassium 148
Clin 142
MPP 134
MPP 134
Phe 131
3,4-dihydroxyphenylalanine 130
DOPAC 129
ethanol 128
methionine 116
glucose 113
Neuronal 112
tryptophan 110
acetate 108
tryptophan 106
Norepinephrine 105
more...