Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.16.2 (tyrosine hydroxylase)
 14,760 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
KIAA1024L 11.1
transmembrane protein 195 11.1
CDP2 11.1
tyrosine hydroxylase isoform 2 11.1
tyrosine hydroxylase 11.0
tyrosine 3-monooxygenase 11.0
TH protein 10.7
PTPRO protein 10.1
protein kinase C alpha type 10.1
UBX domain protein 11 10.1
tyrosinase precursor 10.1
AMPA 3 10.1
ARHGAP10 protein 10.1
paired-like homeodomain transcription factor 3 9.9
phenylethanolamine N-methyltransferase 9.6
Transforming growth factor-beta 3 9.5
VIP2R 9.5
tyrosine hydroxylase isoform 1 9.5
potassium channel 2 9.5
fibronectin leucine rich transmembrane protein 3 9.5
more...
Disease
Abnormal chorionic villi 11.1
Congenital aqueductal stenosis 10.1
Sensory neglect 10.1
Sympathetic paraganglioma 10.1
Peripheral neuroblastoma 9.5
DYT14 9.5
Supranuclear ophthalmoplegia 9.5
DYT4 8.6
DYT2 8.4
Chronic hypernatremia 8.3
NSD 8.3
GTP cyclohydrolase I deficiency 8.1
ASMD 7.9
DRD 7.9
Food hoarding 7.8
JPD 7.8
Juvenile Parkinsonism 7.6
PARK10 7.6
DYT7 7.6
Chronic hypotension 7.5
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Symptom
Lightening 7.5
Circling 6.1
Postural tremor 5.9
bradykinesia 5.9
POA 5.8
Motor dysfunction 5.7
impaired motor coordination 5.5
Rest tremor 5.3
Deafferentation 5.3
Stepping 5.2
No toxic effect 4.7
Behavioral symptoms 4.7
dystonia 4.5
Excitability 4.3
cardiovascular impairment 4.3
motor symptom 4.2
muscle rigidity 4.2
functional recovery 4.0
loss of equilibrium 3.9
acute stress 3.9
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Drug
Liver hydrolysate 10.1
Brocresine 8.5
3,4-Dihydroxyphenylalanine 8.1
Pitressin tannate 7.9
Bupleurum root 7.9
Ipecac syrup 7.5
BH4 7.4
Uncaria hook 7.3
Doca 7.2
L-tyrosine 7.0
Pramipexole 6.9
Pramipexole 6.8
Pentolinium 6.6
7-Nitroindazole 6.6
Deferoxamine mesylate 6.6
Lergotrile 6.6
Reserpine 6.5
Ddc 6.5
Fluspirilene 6.4
Betoptic 6.4
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Enzyme
EC 2.1.1.29 11.1
tyrosine hydroxylase 11.1
phenylethanolamine N-methyltransferase 9.6
aromatic L-amino acid decarboxylase 9.3
dopamine beta-hydroxylase 9.2
pterin-4alpha-carbinolamine dehydratase 9.1
DOPA decarboxylase 8.7
tryptophan hydroxylase 8.5
GTP cyclohydrolase I 8.5
6-pyruvoyltetrahydropterin synthase 8.3
aspartate 1-decarboxylase 8.3
sepiapterin reductase 7.9
choline acetyltransferase 7.5
amine N-methyltransferase 7.5
phenylalanine hydroxylase 7.5
retinol saturase 7.4
cyclohydrolase 7.4
MPP 7.3
2',3'-cyclic nucleotide phosphohydrolase 7.3
proprotein convertase 2 7.3
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Compound
Gepefrine 10.5
Tetrahydroneopterin 10.1
H 44/68 9.6
DOPA sulfate 9.5
6-methyltetrahydropterin 9.5
C9H17NO2 9.5
C9H17NO2 9.1
Metyrosine 9.1
6R-BH4 8.9
6,7-dimethyl-5,6,7,8-tetrahydropteridine 8.8
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 8.7
Dopaquinone 8.6
MPTP 8.5
Anonaine 8.5
Cephaeline 8.5
1-methyl-1,2,3,6-tetrahydropyridine 8.4
1-benzyl-1,2,3,4-tetrahydroisoquinoline 8.4
Phenylethanolamine 8.3
4-phenyl-1,2,3,6-tetrahydropyridine 8.2
Biopterin 8.1
more...