Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.14.16.2 (tyrosine hydroxylase)
14,760 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein tyrosine hydroxylase 14698 Sep 939 Mol 723 neuropeptide Y 692 substance P 677 dopamine transporter 607 choline acetyltransferase 535 olfactory 526 dopa decarboxylase 443 glial fibrillary acidic protein 441 dopamine beta-hydroxylase 436 calcitonin 435 axonal 395 polypeptide 333 nitric oxide synthase 326 GABA 318 somatostatin 312 calbindin 293 nerve growth factor 289 TH protein 287 tryptophan hydroxylase 278 brain-derived neurotrophic factor 253 glial cell line-derived neurotrophic factor 252 glutamic acid decarboxylase 243 peroxidase 242 prolactin 241 acetylcholinesterase 231 galanin 220 AMP 217 synuclein 217 vesicular monoamine transporter 2 215 phenylethanolamine N-methyltransferase 211 calretinin 200 vasoactive intestinal peptide 196 beta-endorphin 195 caspase-3 191 insulin 186 alpha-synuclein 178 neurotrophic factor 177 Nurr1 169 methyltransferase 166 5-hydroxytryptamine 165 ATP 150 parvalbumin 150 c-fos 149 cholecystokinin 149 A431 148 vasopressin 141 neuronal nitric oxide synthase 138 MPP 134 lipopolysaccharide 131 vasoactive intestinal peptide (VIP) 128 oxytocin 128 superoxide dismutase 125 neurotensin 124 synaptophysin 119 Bcl-2 118 dynorphin 113 tyrosinase 113 phenylalanine hydroxylase 111 gut 109 glutamate decarboxylase 106 tyrosine 3-monooxygenase 104 PGP 9.5 102 adenylate cyclase 101 ERK1 96 inducible nitric oxide synthase 96 vesicular acetylcholine transporter 96 E14 95 NSD 92 neuron-specific enolase 91 calmodulin 91 Neuropeptide Y 89 DA transporter 89 neurotrophin 84 tumor necrosis factor 84 MAO-B 84 ubiquitin 83 ACTH 83 corticotropin-releasing factor 83 cytokine 82 catalase 80 endoplasmic reticulum 79 GSH 77 angiotensin II 76 Gen 76 nestin 74 NGF 73 GTP cyclohydrolase I 73 glucagon 70 NMDA receptor 70 cAMP-dependent protein kinase 68 DAT 68 TNF 67 CREB 67 orexin 67 opioid receptor 66 phosphoprotein 66 dopamine D2 receptor 66 chromogranin A 66 DARPP-32 65 SCH 65 E12 64 norepinephrine transporter 63 CA1 63 PKA 61 Leu-enkephalin 61 NPY 60 oxidoreductase 59 LHRH 59 estrogen receptor 58 epidermal growth factor 58 MAO-A 58 sonic hedgehog 57 A11 56 glucocorticoid receptor 55 PRL 54 cage 53 GAD67 53 IL-6 53 A14 53 catechol-O-methyltransferase 52 ERK 52 proenkephalin 51 phosphodiesterase 50 p38 50 nicotinic acetylcholine receptor 50 NADPH 50 glutamate receptor 49 extracellular signal-regulated kinase 49 proteasome 49 GTP 48 MAPK 48 VMAT2 48 asymmetrical 47 lactate dehydrogenase 47 diaphorase 47 collagen 47 GDNF 47 dopamine D1 receptor 46 serotonin transporter 46 pituitary adenylate cyclase-activating polypeptide 46 Ang II 46 glutathione peroxidase 45 proopiomelanocortin 45 VIP 45 dopa-responsive dystonia 44 vesicular glutamate transporter 2 44 neurotrophin-3 43 renin 43 leptin 42 p53 42 enolase 41 microtubule-associated protein 41 A15 40 vascular endothelial growth factor 40 E16 40 cyclooxygenase-2 39 adenylyl cyclase 39 GCH 38 more...

Disease Parkinson's disease 2796 parkinsonism 351 neuroblastoma 275 depression 237 varices 234 pheochromocytoma 232 Alzheimer's disease 222 schizophrenia 196 tumor 183 hypertension 178 cold 119 cancer 118 diabetes 100 NSD 92 addiction 84 obesity 79 GSH 78 ischemia 77 SCH 65 cholera 61 drug addiction 59 Huntington's disease 57 movement disorder 55 melanoma 54 dementia 51 dyskinesia 50 stroke 48 akinesia 48 Evans 47 catalepsy 45 bipolar disorder 44 aggression 43 hyperprolactinemia 41 herpes simplex 40 epilepsy 40 celiac disease 39 heart failure 39 myocardial infarction 39 hypoglycemia 37 GAD 37 cognitive impairment 34 uterus 33 ADHD 31 psychosis 30 NAME 28 SEM 28 neurological disease 27 Neuroblastoma 26 Neuroblastoma 26 alcoholism 25 chronic pain 25 autism 25 type 2 diabetes 24 cerebral ischemia 24 ATM 23 Dementia with Lewy bodies 23 Pituitary 23 abnormal involuntary movements 23 phenylketonuria 22 encephalopathy 22 suicide 22 PHA 22 hyperglycemia 22 SDS 21 memory impairment 21 major depressive disorder 21 Brown 20 metastases 20 chronic renal failure 20 Pineal 20 sudden infant death syndrome 20 amyotrophic lateral sclerosis 20 hypothyroidism 19 social stress 18 glioma 18 drug abuse 18 mental illness 18 hyperphenylalaninemia 18 tumor growth 18 dehydration 17 urethra 17 HPA 16 malnutrition 16 posttraumatic stress disorder 16 carcinoma 15 progressive supranuclear palsy 15 anxiety disorders 15 minimal residual disease 15 neuropathy 15 hemiparkinsonism 14 HIV 14 disinhibition 14 affective disorder 14 paraganglioma 14 plaque 14 cytomegalovirus 13 hyperthyroidism 13 DRD 13 tumorigenesis 13 pertussis 13 EDA 13 virus infection 13 substance abuse 13 Rett syndrome 13 mole 13 embryonal carcinoma 13 mole 13 immunodeficiency 13 cardiovascular disease 12 B-cell lymphoma 12 arthritis 12 psychological stress 12 restless legs syndrome 12 essential hypertension 12 congestive heart failure 12 multiple sclerosis 11 hyperphagia 11 ureter 11 hyperinsulinemia 11 fits 11 ventricular hypertrophy 11 hepatocellular carcinoma 11 Carotid body 11 Carotid body 11 coronary artery disease 11 periosteum 11 anemia 11 Carotid body 11 cocaine addiction 11 Blocking 10 aggressiveness 10 anhedonia 10 mental retardation 10 PSA 10 leukemia 10 myopia 10 solid tumor 10 stereotypies 10 Disorder 9 sleep disorders 9 ganglioneuroma 9 diabetic retinopathy 9 cornea 9 PPP 9 torsion dystonia 9 infectious diseases 9 respiratory infection 9 polycystic ovary syndrome 9 Dependence 9 mental retardation 9 iron deficiency 9 migraine 8 immaturity 8 seminal vesicles 8 DYT1 8 breast cancer 8 myocardial ischemia 8 type 1 diabetes 8 emotionality 8 vagina 8 more...

Symptom pain 131 functional recovery 99 dystonia 91 tremor 68 bradykinesia 63 seizures 53 anesthesia 36 acute stress 32 hypercapnia 22 ataxia 21 hypothermia 19 analgesia 17 POA 14 starvation 12 constipation 12 thinning 10 muscle rigidity 9 chorea 9 fatigue 9 anorexia 8 syncope 8 hyperoxia 8 myoclonus 7 despair 7 abnormal gait 7 hunger 7 collapse 6 agitation 6 vomiting 6 diarrhea 5 Stepping 5 hypotonia 5 incoordination 5 impaired motor coordination 4 motor symptom 4 sleepiness 4 exhaustion 4 fasciculation 4 headache 4 Excitability 3 neurological disability 3 insomnia 3 Deafferentation 3 lethargy 3 colic 3 distraction 3 cachexia 3 catatonia 2 cerebellar ataxia 2 Circling 2 neuralgia 2 ophthalmoplegia 2 anosmia 2 loss of balance 2 torticollis 2 Motor dysfunction 2 hypersomnia 2 twitching 2 excessive sweating 2 back pain 2 masculinization 2 nausea 2 weakness 2 spasticity 2 acute pain 2 polydipsia 1 aphagia 1 cardiovascular impairment 1 photophobia 1 nausea and vomiting 1 Neuropathic pain 1 spasm 1 physical appearance 1 general problem 1 Decreased activity 1 exertional dyspnea 1 cough 1 chronic constipation 1 dizziness 1 DNA marker 1 abnormal breathing 1 pallor 1 Ill 1 arthralgia 1 memory loss 1 paresthesia 1 flank pain 1 Lightening 1 intention tremor 1 tonic-clonic seizure 1 tachypnea 1 pachyonychia 1 knee pain 1 myalgia 1 cancer pain 1 loss of equilibrium 1 overweight 1 dry eye 1 erythema 1 bone pain 1 Postural tremor 1 athetosis 1 ACHE 1 low back pain 1 adipsia 1 ataxic gait 1 shoulder pain 1 vertigo 1 Rest tremor 1 Behavioral symptoms 1 No toxic effect 1 orofacial pain 1

Drug L-tyrosine 144 BH4 123 Nephron 106 HCH 76 Reserpine 43 Apomorphine 42 lysine 39 nitroglycerin 38 p75 37 CSF 35 caffeine 28 Forskolin 28 NADH 27 ascorbate 26 Dermatol 24 Ethanol 21 ROS 21 Angiotensin II 21 Parkin 20 MAP 20 Parkin 20 EE2 18 DHT 17 DHT 16 Cardiovasc 15 Clonidine 15 Histamine 15 9-THC 14 Retinoic acid 14 Gel 13 Pramipexole 11 Pramipexole 11 vitamin E 11 Secretin 10 3,4-Dihydroxyphenylalanine 10 ICI 10 Portal 10 ENT 9 ABC 9 PCP 7 Sinemet 7 Diurnal 7 Monit 7 Glucagon 6 CaCl2 6 CaCl2 6 CaCl2 6 IFN-gamma 6 CTX 6 Zonisamide 6 GHRP 6 Guanethidine 6 Frontal 6 ETS 5 Sinemet 5 Atropine 5 Doxycycline 5 IL-2 5 Phentolamine 5 Paraffin 5 Glutathione 5 Kainic acid 5 EPL 5 Activin 5 IL-11 5 Sinemet 5 Indomethacin 5 DNase I 5 RFP 4 Modafinil 4 Sulpiride 4 7-Nitroindazole 4 Heme 4 Estrogens 4 Pitressin 4 Ddc 4 CAM 4 NBT 4 ETA 4 Luteinizing 4 Madopar 4 Vitamin B 3 Tacrolimus 3 CFT 3 Desferal 3 Sodium nitroprusside 3 Rasagiline 3 Cilostazol 3 Rosiglitazone 3 DMI 3 Growth hormone 3 Rolipram 3 G418 3 PFT 3 ALA 3 Nitric Oxide 3 Growth hormone 3 Carbidopa 3 GRF 3 ACT 3 Bayer 3 Ritalin 2 Mazindol 2 Thioridazine 2 Trifluoperazine 2 Leaf 2 Capsicum 2 OMP 2 THA 2 PCB 2 Ginseng 2 CoCl2 2 CoCl2 2 pyridoxal phosphate 2 Amiloride 2 Benserazide 2 Atomoxetine 2 Desferal 2 G-CSF 2 Alanine 2 Safflower 2 Propofol 2 Adenosine deaminase 2 Pravastatin 2 Captopril 2 IL-1ra 2 Aloe 2 Lovastatin 2 TEL 2 Lisuride 2 KAN 2 Amiloride 2 Ringer's solution 2 Domperidone 2 niacin 2 CPT-11 2 Ritanserin 2 LCM 2 LCM 2 Vitamin A 2 balanced salt solution 2 Meth 2 Methylprednisolone 1 MDS 1 beta-Galactosidase 1 PFA 1 DEX 1 DMAP 1 Flunitrazepam 1 Ouabain 1 Gelatin 1 Copaxone 1 Horizon 1 TTC 1 Tirilazad mesylate 1 VCR 1 FeCl3 1 Bezafibrate 1 Anakinra 1 Betoptic 1 more...

Enzyme tyrosine hydroxylase 14760 choline acetyltransferase 538 protein kinase 384 dopamine beta-hydroxylase 379 tryptophan hydroxylase 294 monoamine oxidase 278 peroxidase 269 mitogen-activated protein kinase 250 acetylcholinesterase 228 phenylethanolamine N-methyltransferase 215 DOPA decarboxylase 203 protein kinase C 167 aromatic L-amino acid decarboxylase 158 caspase-3 157 superoxide dismutase 142 MPP 134 NADPH-diaphorase 119 tyrosinase 116 phenylalanine hydroxylase 115 NO synthase 115 glutamate decarboxylase 113 GTP cyclohydrolase I 108 adenylate cyclase 105 ERK 93 catalase 90 AMPK 74 complex I 69 DAT 68 NQO1 64 luciferase 53 diaphorase 51 phosphodiesterase 50 NOS 50 proteasome 50 lactate dehydrogenase 49 diaphorase 49 calcineurin 46 beta-galactosidase 46 glutathione peroxidase 45 renin 43 NADPH oxidase 42 enolase 41 reverse transcriptase 40 CaMKII 40 NADPH oxidase 39 phenol oxidase 36 cyclohydrolase 33 guanylate cyclase 32 MEK 30 chloramphenicol acetyltransferase 28 dihydropteridine reductase 26 GSK 25 alkaline phosphatase 24 ATPase 24 trypsin 23 focal adhesion kinase 23 DCF 21 glutamine synthetase 21 ACS 21 sepiapterin reductase 20 phospholipase C 20 succinate dehydrogenase 19 ornithine decarboxylase 18 cytochrome oxidase 18 RNase 18 RNase 18 cholinesterase 18 histidine decarboxylase 17 aldehyde dehydrogenase 17 aldehyde dehydrogenase 17 caspase-9 17 glutathione reductase 17 aldehyde dehydrogenase 17 aldehyde dehydrogenase 17 aldehyde dehydrogenase 17 RNA polymerase 16 AMP-activated protein kinase 15 phosphatidylinositol 3-kinase 14 protein phosphatase 2A 14 catechol O-methyltransferase 13 glyceraldehyde-3-phosphate dehydrogenase 13 heme oxygenase 12 GABA transaminase 11 thrombin 11 transcriptase 11 caspase-1 11 PARP 11 PDE 10 caspase-8 10 glutathione S-transferase 10 MAP 9 tyrosine decarboxylase 9 glyceraldehyde-3-phosphate dehydrogenase 8 CAD 8 arylalkylamine N-acetyltransferase 8 laccase 8 glyceraldehyde-3-phosphate dehydrogenase 8 ribonuclease 8 ribonuclease 8 CAD 8 CAD 8 adenosine deaminase 7 ACE 7 PCP 7 collagenase 7 chymotrypsin 7 phosphoinositide 3-kinase 7 6-pyruvoyltetrahydropterin synthase 7 phospholipase A2 7 glutaminase 7 carbonic anhydrase 7 adenosine deaminase 7 glyceraldehyde-3-phosphate dehydrogenase 6 CNPase 6 Thy1 6 PAT 6 tyrosine aminotransferase 6 aspartate aminotransferase 6 gamma-glutamylcysteine synthetase 6 proteinase K 6 glutamate dehydrogenase 6 glutamate dehydrogenase 6 thymidine kinase 6 glyceraldehyde-3-phosphate dehydrogenase 6 S1 nuclease 6 N-acetyltransferase 6 endonuclease 6 xanthine oxidase 5 PAH 5 alcohol dehydrogenase 5 chondroitinase 5 PKG 5 NADH dehydrogenase 5 lipoxygenase 5 AMPK 5 hyaluronidase 5 prolyl hydroxylase 5 aldose reductase 5 chondroitinase 5 creatine kinase 5 acid phosphatase 4 CPT 4 CPT 4 ceruloplasmin 4 hormone-sensitive lipase 4 lipase 4 cdc2 4 ribonucleotide reductase 4 pyruvate dehydrogenase 4 lipoprotein lipase 4 ribonucleotide reductase 4 tissue plasminogen activator 4 CPT 4 isopeptidase 4 citrate synthase 3 2',3'-cyclic nucleotide phosphohydrolase 3 thyroid peroxidase 3 STR 3 caspase-11 3 pterin-4alpha-carbinolamine dehydratase 3 more...

Compound Dec 1076 tyrosine 878 MPTP 875 noradrenaline 765 L-DOPA 688 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 622 calcium 504 Dopamine 437 oxygen 410 5-HT 367 glutamate 360 GABA 327 DNA 327 GABA 323 cAMP 305 water 276 nitric oxide 234 AMP 222 gamma-aminobutyric acid 205 sodium 186 Dopa 181 iron 167 silver 160 ATP 150 phosphate 149 potassium 148 Clin 142 MPP 134 MPP 134 Phe 131 3,4-dihydroxyphenylalanine 130 DOPAC 129 ethanol 128 methionine 116 glucose 113 Neuronal 112 tryptophan 110 acetate 108 tryptophan 106 Norepinephrine 105 retinoic acid 105 tryptophan 104 tryptophan 104 Adrenal 101 fluorine 97 serine 93 Methamphetamine 90 leucine 83 GSH 82 GSH 82 arginine 80 DBH 76 ACTH 74 nicotinamide 70 HVA 69 Substance P 69 DAT 68 His 67 TNF 67 hydroxyindoleacetic acid 66 sulfate 66 Nicotine 66 manganese 65 salt 65 NMDA 62 hydrogen 59 Rotenone 55 5-hydroxytryptophan 54 GTP 51 NADPH 51 NADPH 50 formaldehyde 48 cysteine 48 zinc 48 nitrogen 47 lysine 46 formaldehyde 44 alanine 44 cGMP 43 Reserpine 43 6-Hydroxydopamine 41 pteridine 41 acetic acid 41 Ile 39 copper 38 Melatonin 36 isoleucine 35 isoleucine 35 Cocaine 35 MPT 34 Insulin 34 aldehyde 34 4-phenyl-1,2,3,6-tetrahydropyridine 33 Morphine 33 AMPA 33 Tyrosine 32 Estrogen 32 bromide 31 aldehyde 31 ACh 31 Ang II 31 HCl 31 dUTP 31 Estrogen 30 Amphetamine 30 CO2 30 Haloperidol 30 Haloperidol 30 Amphetamine 30 GM1 30 MTT 29 Forskolin 28 caffeine 28 aldosterone 28 NADH 26 Tetrahydrobiopterin 25 pyridine 24 6-methyltetrahydropterin 24 Angiotensin II 24 SDS 23 Coronal 23 Cereb 23 threonine 23 TRH 23 H2O2 23 Estradiol 22 glutamic acid 22 Calcitonin 22 galactose 22 Retinal 22 Mg2+ 21 glutamine 21 ACS 21 Glutamate 21 ACS 21 5-HIAA 20 Dexamethasone 20 Gly 20 ADP 19 1,2,3,4-tetrahydroisoquinoline 19 ADP 19 ADP 19 1,2,3,6-tetrahydropyridine 19 Paraquat 19 Paraquat 19 1,2,3,6-tetrahydropyridine 19 Capsaicin 18 NAD 18 Salt 18 TSH 18 iodine 18 cobalt 18 Testosterone 18 Testosterone 18 DDC 17 DDC 17 PEG 17 Cardiol 17 PAP 17 PAP 17 more...

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