Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.14.3 (luciferase)
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Human Gene/Protein
GCHFR 9.7
KIAA0785 9.7
FBXO10 protein 9.7
CCDC127 9.7
ADAMTS9 protein 9.7
Progestin and adipoQ receptor family member VI 9.7
homeobox protein A7 9.7
SHOX2 protein 9.7
trigger of mitotic entry 1 9.7
ZNF434 9.7
mutant PAX6 protein 9.7
FOXP4 protein 9.7
CDC2L6 9.7
Adenosine monophosphate deaminase 1 9.7
MRPS18A 9.7
Na+/K+ transporting ATPase interacting 2 9.7
epsin 2a 9.7
collagen, type X, alpha 1 9.7
Rho GTPase activating protein 10 9.7
NR3C2 protein 9.7
elongation factor RNA polymerase II 9.7
RNA binding motif protein 35A 9.7
putative homeodomain transcription factor 2 9.7
ZBTB4 protein 9.7
LDHAL6A protein 9.7
FLJ33360 9.7
F-box protein 10 9.7
HSPC157 9.7
karyopherin alpha 6 9.7
RPB11a 9.7
ubiquitin specific protease 39 9.7
TCP10L protein 9.7
HZF2 9.7
Fibroblast growth factor 12 9.7
ERVK4 9.7
thioesterase superfamily member 4 9.7
Growth hormone inducible transmembrane protein 9.7
PUM2 protein 9.7
zinc finger, AN1-type domain 5 9.7
MORC family CW-type zinc finger 4 9.7
OR51S1 9.7
ZNF549 9.7
non-protein coding RNA 174 9.7
cathepsin L splice variant 9.7
chromosome 21 open reading frame 91 9.7
NPCEDRG 9.7
ERVK5 9.7
Ras-related protein Rab-27B 9.7
neuronal PAS domain protein 1 9.7
FR-gamma' 9.7
tryptophanyl tRNA synthetase 2, mitochondrial 9.7
non-protein coding RNA 52 9.7
SPIN3 9.7
ZBTB17 protein 9.7
baculoviral IAP repeat-containing 6 9.7
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 9.7
FOXH1 protein 9.7
mitochondrial trans-2-enoyl-CoA reductase 9.7
ubiquitin specific peptidase 36 9.7
CCDC152 9.7
NUP214 protein 9.7
breast cancer metastasis-suppressor 1-like 9.7
ATP8A1 protein 9.7
MHC class II HLA-DQ 9.7
Lipoma HMGIC fusion partner-like 3 9.7
Inositol polyphosphate-1-phosphatase 9.7
ZNF438 9.7
MAD2 mitotic arrest deficient-like 2 9.7
phosphoinositide-3-kinase adaptor protein 1 9.7
FAM163B 9.7
interleukin 17 receptor D 9.7
Interferon regulatory factor 2 binding protein 2 9.7
Na+/Ca2+ exchanger isoform 3 9.7
ATP-dependent RNA helicase A 9.7
Familial acute myelogenous leukemia related factor 9.7
IFNT1 9.7
branched chain keto acid dehydrogenase E1, alpha polypeptide 9.7
BTF3L4 9.7
placenta expressed transcript 1 9.7
WNT10B protein 9.7
more...
Disease
Antibody-mediated anemia 9.7
Pre-B-Cell Leukemia 8.7
Diarrhea predominant irritable bowel syndrome 8.7
PGL3 8.2
Gastrointestinal motility disorder 8.1
OASF 8.1
AUNA1 7.7
SCA26 7.7
PIN-1 7.4
LCA9 7.4
PGL4 7.1
ECL cell carcinoid 7.1
THC2 7.1
HTC1 6.9
Raccoonpox 6.9
CACD 6.9
LI2 6.8
GSM1 6.7
CACD 6.7
osteolytic sarcoma 6.7
AGS4 6.5
Android obesity 6.5
TLPD 6.5
AS1 6.5
Poxvirus infection 6.4
Chronic apical periodontitis 6.4
Picornavirus infection 6.2
Invasive Carcinoma 6.2
Acute prostatitis 6.2
SLC34A3, 6.2
Silence 6.2
TYS 6.2
internal lesion 6.1
Pleural metastases 6.1
skin pigmentation disorder 6.0
Dourine 5.9
Mink enteritis 5.9
RCC2 5.9
CEBPG 5.8
skin hyperkeratosis 5.8
pituitary cancer 5.7
IGHD II 5.7
Hereditary folate malabsorption 5.7
BFNC 5.7
Fibrodysplasia ossificans progressiva 5.6
AML progression 5.6
Cyanotic congenital heart disease 5.6
Vaccinia virus infection 5.6
IMD1 5.5
Pulmonary failure 5.5
DFNA15 5.5
Osteosarcoma 5.5
Osteosarcoma 5.5
PGL2 5.5
Zar 5.5
SMARD1 5.5
Lumbar disc degeneration 5.5
multiple synostoses syndrome 5.5
cancer angiogenesis 5.4
Mammary adenocarcinoma 5.4
Omsk hemorrhagic fever 5.3
Cerebellar degeneration 5.3
BPES 5.3
EMT 5.3
bacterial colitis 5.2
choroid plexus tumor 5.2
AGS 5.2
laryngeal squamous cell carcinoma 5.2
Andermann syndrome 5.1
Telogen effluvium 5.1
scalp dermatitis 5.1
FIH 5.1
Chronic actinic dermatitis 5.1
Xeroderma pigmentosum group C 5.1
WT3 5.1
testicular embryonal carcinoma 5.0
AD10 5.0
HCA1 5.0
Chronic HIV infection 4.9
OCA4 4.9
more...
Symptom
cardiovascular disability 5.9
Scratch 4.5
ACHE 3.8
female puberty 3.8
Inflammatory pain 3.5
No toxic effect 3.4
menopausal symptoms 3.2
catarrh 3.1
Neuropathic pain 2.9
Visceral pain 2.8
photopsia 2.6
hyperoxia 2.2
hot flashes 2.0
Cushingoid 2.0
Cushingoid 1.9
masculinization 1.8
starvation 1.7
intention tremor 1.3
Poor sleep 1.2
loss of taste 1.2
skin damage 1.1
Halo 0.9
neurological disability 0.8
functional recovery 0.7
nipple discharge 0.7
nipple discharge 0.6
Anoxia 0.6
pelvic pain 0.5
photophobia 0.1
cachexia 0.0
respiratory distress 0.0
general problem -0.1
cerebellar ataxia -0.1
DNA marker -0.2
Stiffness -0.3
HSA -0.3
otalgia -0.3
polyuria -0.3
arthralgia -0.3
bone pain -0.3
hypersomnia -0.3
joint stiffness -0.3
urinary frequency -0.4
productive cough -0.4
abnormal gait -0.4
hypoproteinemia -0.4
nasal congestion -0.4
night sweats -0.5
dental pain -0.5
memory loss -0.5
hot flushes -0.6
chronic constipation -0.6
fasciculation -0.6
myalgia -0.7
nasal discharge -0.7
bitter taste -0.8
hepatomegaly -0.8
exhaustion -0.9
physical appearance -0.9
cancer pain -0.9
splenomegaly -1.0
low back pain -1.0
dystonia -1.0
acidity -1.0
abdominal discomfort -1.0
neuralgia -1.1
sneezing -1.2
collapse -1.2
ataxia -1.3
leg pain -1.3
twitching -1.3
pain -1.3
chills -1.4
polydipsia -1.4
diarrhea -1.4
anesthesia -1.4
Wind -1.6
dry eye -1.7
tremor -1.7
hypercapnia -1.7
more...
Drug
Pelitinib 8.7
Coelenteramide 8.1
Rivoglitazone 8.1
Doramapimod 8.1
Mubritinib 7.4
Butyramide 7.4
Fingolimod hydrochloride 7.0
Proflavin 6.4
Balanol 6.4
Hymenialdisine 6.4
CTZ 6.3
Alsterpaullone 6.1
Trimegestone 6.1
Benidipine hydrochloride 5.8
R1881 5.8
Equilenin 5.5
ENX 5.3
Myotrophin 5.3
Bindarit 5.2
Purvalanol 5.2
Cognex 5.1
Eusolex 5.1
Cardura 5.0
Cardura 5.0
GEO 5.0
Eusolex 4.9
Tolfenamic acid 4.9
1,4-Butanediol 4.8
Carboxyatractyloside 4.8
Adenosine Monophosphate 4.8
Fluorescein sodium 4.8
Sulfaphenazole 4.7
Optison 4.7
Marimastat 4.5
DNase I 4.5
Acemannan 4.5
ICI 4.5
Ilomastat 4.5
Casodex 4.4
Vesnarinone 4.4
Paxil 4.4
hCRH 4.4
Ciglitazone 4.4
Gel 4.4
Indoprofen 4.4
FSH-beta 4.3
Gentian violet 4.3
FSH-beta 4.3
Optison 4.3
Amlexanox 4.2
Paxil 4.2
Paxil 4.2
Pirarubicin 4.2
Lactase 4.1
Benzofuran 4.1
Penfluridol 4.1
Rebamipide 4.1
ETS 4.0
Allegra 4.0
Creosote 4.0
Allegra 4.0
FSH-beta 4.0
RFP 4.0
Beraprost 3.9
beta-Galactosidase 3.9
G418 3.9
Adenosine triphosphate 3.8
Activin 3.8
Butaprost 3.7
Forskolin 3.7
Rosuvastatin calcium 3.7
Colestipol 3.7
Beraprost sodium 3.7
Pregnyl 3.7
Hyperforin 3.6
Radicicol 3.6
Rosiglitazone 3.6
Evista 3.6
DPE 3.6
Flavopiridol 3.6
more...
Enzyme
luciferase 9.7
luciferin sulfotransferase 9.7
Oplophorus luciferase 9.2
acyl-protein synthetase 8.7
firefly luciferase 8.6
Cypridina luciferase 8.5
21-hydroxysteroid dehydrogenase 8.1
matrix metalloproteinase-15 8.1
21-hydroxysteroid dehydrogenase 8.1
hippostasin 8.1
phosphatidylinositol N-acetylglucosaminyltransferase 7.7
melilotate hydroxylase 7.1
17-ketoreductase 6.7
SsuE 6.7
acyl-CoA reductase 6.6
alpha-1,4-glucan lyase 6.5
2-alkenal reductase 6.2
flavin reductase 6.2
SsuD 6.1
2-alkenal reductase 6.0
kallikrein 10 5.9
phosphoethanolamine cytidylyltransferase 5.7
p-hydroxyphenylacetate 3-hydroxylase 5.6
matrix metalloproteinase 14 5.6
inositol polyphosphate 4-phosphatase 5.5
PqqC 5.5
CYP39A1 5.5
ecdysone oxidase 5.5
NADPH:quinone oxidoreductase 5.4
dihydrolipoyl transacylase 5.4
matrilysin-2 5.4
CYP7B1 5.3
hydroxyquinol 1,2-dioxygenase 5.3
PrpD 5.2
GAS 5.1
HK2 5.1
S-adenosylhomocysteine nucleosidase 5.1
ComC 5.1
pinene synthase 5.1
25-hydroxyvitamin D3 1alpha-hydroxylase 5.1
ADP-dependent glucokinase 5.0
anthranilate hydroxylase 5.0
phytanoyl-CoA hydroxylase 4.9
DNA 3'-phosphatase 4.9
arsenite methyltransferase 4.9
2A protease 4.9
protein acyltransferase 4.8
UDP-galactose:ceramide galactosyltransferase 4.8
CYP8B1 4.8
caspase-5 4.8
GD3 synthase 4.7
IKK 4.7
nucleoside triphosphate phosphohydrolase 4.7
thymidine kinase 4.7
ATP sulfurylase 4.7
cytosine deaminase 4.7
EC 3.6.1.17 4.7
hydroxyprostaglandin dehydrogenase 4.7
VanX 4.7
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.6
matrix metalloproteinase 10 4.6
organomercurial lyase 4.5
nicotine oxidase 4.5
amorpha-4,11-diene synthase 4.5
CYP7A1 4.5
putrescine oxidase 4.5
aequorin 4.4
fatty-acid synthase 4.4
1-deoxy-D-xylulose-5-phosphate synthase 4.4
3-hydroxyisobutyrate dehydrogenase 4.4
myo-inositol oxygenase 4.4
CMP kinase 4.4
retinoid isomerase 4.3
N-acetylmannosamine kinase 4.3
phenylethanolamine N-methyltransferase 4.3
MEKK1 4.3
gamma-glutamylcysteine synthetase 4.3
apyrase 4.3
fructan exohydrolase 4.3
fluorinase 4.3
more...
Compound
Erioflorin 9.7
N-phenylethanethioamide 9.7
C25H36O4 9.7
C25H36O4 9.7
C25H36O4 9.7
2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 9.7
C25H36O4 9.7
3-aminodihydro-2(3H)-furanone 9.7
2-Acetyldibenzothiophene 9.7
C25H36O4 9.7
Evoxine 9.7
Bowdichione 9.7
C25H36O4 9.7
C25H36O4 9.7
butyl thiocyanate 9.7
C25H36O4 9.7
2,2',3',4',6'-Pentachloro-4-biphenylol 9.7
Eurycomalactone 9.1
Photinus luciferin 9.1
AO 425 8.7
C10H13N3O3 8.7
C11H13NO5 8.7
C11H13NO5 8.7
C11H13NO5 8.7
Tetradecanoyl-CoA 8.7
C11H13NO5 8.7
C10H13N3O3 8.7
C11H13NO5 8.7
C11H13NO5 8.7
2,2',3,3',4',5,5'-heptachloro-4-biphenylol 8.7
C10H13N3O3 8.7
C10H13N3O3 8.7
C10H13N3O3 8.7
C11H13NO5 8.7
C10H13N3O3 8.7
C11H13NO5 8.7
C10H13N3O3 8.7
C10H13N3O3 8.7
1,3,6-tribromo-9H-carbazole 8.7
C16H16O3 8.7
C10H13N3O3 8.7
3-aminodihydro-2(3H)-furanone 8.7
C11H13NO5 8.7
C11H13NO5 8.7
C11H13NO5 8.7
C14H14O2 8.7
C10H13N3O3 8.7
C11H13NO5 8.7
C11H13NO5 8.7
C10H13N3O3 8.7
C10H13N3O3 8.7
C11H13NO5 8.7
C11H13NO5 8.7
C10H13N3O3 8.1
C10H13N3O3 8.1
C10H13N3O3 8.1
(+)-Syringaresinol 8.1
C10H13N3O3 8.1
C10H13N3O3 8.1
C10H13N3O3 8.1
C11H13NO5 8.1
FMNH 7.9
reduced riboflavin 7.8
3,6-dichloro-9H-carbazole 7.7
1-pyrrolidinecarbodithioic acid 7.7
GW 7647 7.7
Zaluzanin C 7.7
C20H14O4 7.7
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde 7.7
1H-indole-3-carbonitrile 7.7
3,6-dibromo-9H-carbazole 7.7
C12H5Br4N 7.7
Acetophenone oxime 7.7
tetradecanal 7.6
tetradecanal 7.6
Methyl isobutyl carbinol 7.4
Curvularin 7.4
4-Chlorobiphenyl 7.4
Isobrucein B 7.4
Copper 8-hydroxyquinoline 7.4
more...