Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.14.14.3 (
luciferase
)
38,195
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
5138
UTR
2607
Sep
2517
fused
1133
ATP
1076
cytokine
984
Sp1
917
p53
820
AP-1
719
insulin
696
p65
683
catenin
639
IL-6
631
TNF
628
lipopolysaccharide
627
tumor necrosis factor
618
caspase-3
577
estrogen receptor
576
AKT
560
p38
559
MAPK
544
CCK
510
ERK
500
collagen
486
interferon
453
PI3K
450
c-Jun
430
ERK1
415
Bcl-2
414
osteosarcoma
400
kit
390
p21
386
vascular endothelial growth factor
370
AMP
352
androgen receptor
345
IFN
339
E-cadherin
338
LPS
338
JNK
327
cyclin D1
320
STAT3
320
CREB
294
IL-8
293
osteogenic
285
histone
284
glucocorticoid receptor
281
HEK
278
nuclear receptor
268
alkaline phosphatase
267
aryl hydrocarbon receptor
266
mTOR
264
Nrf2
260
polypeptide
248
TNF-alpha
246
inducible nitric oxide synthase
241
p50
239
peroxisome proliferator-activated receptor
235
interleukin-6
235
thymidine kinase
234
extracellular signal-regulated kinase
231
nuclear protein
230
EBP
230
THP
230
MEK
226
DNase I
223
CD4
217
endoplasmic reticulum
217
PTEN
217
cyclooxygenase-2
216
ubiquitin
216
Gen
215
ATPase
208
erythroid
207
matrix metalloproteinase
206
TLR4
197
histone deacetylase
197
AS1
196
tyrosine kinase
196
peroxisome proliferator-activated receptor gamma
193
c-fos
192
more...
Disease
cancer
5867
tumor
5485
breast cancer
1470
hepatocellular carcinoma
1375
tumorigenesis
1299
tumor growth
1262
carcinoma
787
carcinogenesis
751
MCF
693
prostate cancer
647
tumor progression
637
colorectal cancer
633
lung cancer
618
gastric cancer
606
glioma
582
adenocarcinoma
503
osteosarcoma
460
HIV
425
diabetes
405
squamous cell carcinoma
378
non-small cell lung cancer
374
colon cancer
372
melanoma
368
metastases
361
neuroblastoma
356
atherosclerosis
345
leukemia
341
ovarian cancer
316
cervical cancer
300
cytomegalovirus
270
glioblastoma
265
pancreatic cancer
262
ischemia
262
virus infection
238
immunodeficiency
232
Alzheimer's disease
231
hepatitis C
228
obesity
222
hypertension
201
AS1
196
liver cancer
192
renal cell carcinoma
183
osteoarthritis
181
stroke
178
bladder cancer
177
herpes simplex
177
infectious diseases
169
DDP
160
lymphoma
159
osteoporosis
159
type 2 diabetes
157
plaque
153
liver cancer
151
influenza
149
myocardial infarction
149
retinoblastoma
146
B-cell lymphoma
141
Parkinson's disease
136
rheumatoid arthritis
135
asthma
134
EMT
133
cold
130
Hepatocellular carcinoma
124
cardiovascular disease
124
hepatitis B
122
Osteosarcoma
121
Osteosarcoma
121
SCID
119
endometrial cancer
118
acute myeloid leukemia
118
heart failure
117
lung carcinoma
117
Epstein
115
Mycobacterium
114
tuberculosis
109
sepsis
108
diabetic nephropathy
106
sepsis
105
GSH
103
Infection
102
more...
Symptom
pain
127
starvation
98
anesthesia
49
seizures
29
hyperoxia
28
diarrhea
26
functional recovery
26
respiratory distress
24
menopausal symptoms
18
collapse
15
Neuropathic pain
13
masculinization
11
Scratch
11
acidity
9
exhaustion
9
analgesia
8
ataxia
8
arthralgia
7
weakness
7
tremor
7
cachexia
7
pelvic pain
7
low back pain
6
splenomegaly
6
vomiting
6
overweight
6
abdominal pain
6
headache
6
dystonia
5
hot flashes
5
myalgia
5
fatigue
5
nausea
4
ACHE
4
hypothermia
4
discomfort
4
skin damage
4
discomfort
4
cerebellar ataxia
4
hepatomegaly
4
constipation
3
angina
3
polyuria
3
HSA
3
cough
3
dyspnea
3
bone pain
3
hypercapnia
3
memory loss
3
photophobia
2
neurological disability
2
female puberty
2
back pain
2
catarrh
2
cancer pain
2
paresis
2
chills
2
agitation
2
chronic constipation
1
physical appearance
1
productive cough
1
nasal discharge
1
nipple discharge
1
intention tremor
1
Poor sleep
1
Cushingoid
1
nipple discharge
1
DNA marker
1
Anoxia
1
Stiffness
1
dental pain
1
otalgia
1
acute stress
1
bitter taste
1
hypersomnia
1
distraction
1
joint stiffness
1
No toxic effect
1
insomnia
1
myoclonus
1
more...
Drug
Gel
376
lysine
240
DNase I
231
Monit
191
ROS
154
ICI
145
IFN-gamma
128
NADH
123
IL-2
119
Dermatol
100
MAP
79
GEO
58
ETS
52
EE2
48
Cardiovasc
47
Heme
44
CSF
43
Forskolin
42
R1881
42
G418
39
Retinoic acid
36
Angiotensin II
35
PCB
30
IFN-beta
30
Leaf
29
Activin
28
lactose
26
PTH
26
Estrogens
25
RFP
23
caffeine
23
TAT
22
Kenyan
22
vitamin E
20
DHT
19
TTC
19
ADR
19
DHT
19
CoCl2
18
CoCl2
18
Growth hormone
17
ascorbate
17
MRC
17
Docetaxel
17
Growth hormone
16
Ethanol
16
FAD
16
Asthma
16
Asn
16
Arsenic trioxide
16
Glutathione
15
Taxol
15
VCR
15
ROC
15
Adenosine triphosphate
15
Mutagen
15
Adriamycin
14
Glycyrrhiza
14
Propofol
13
ABC
13
Spectrum
13
Alanine
12
Gelatin
12
Glucagon
12
Rosiglitazone
12
Fluorescein
12
DEX
12
ampicillin
12
Sorafenib
12
IL-11
12
Bortezomib
11
CAM
11
ETA
11
Simvastatin
11
HCH
11
Histamine
11
CTX
11
Albumin
10
Parkin
10
Spectrum
10
more...
Enzyme
luciferase
38195
mitogen-activated protein kinase
1613
firefly luciferase
1276
ERK
980
protein kinase
894
protein kinase C
478
focal adhesion kinase
446
caspase-3
410
MEK
370
beta-galactosidase
337
alkaline phosphatase
268
RNA polymerase
252
thymidine kinase
234
glutathione S-transferase
229
RNase
223
RNase
220
ATPase
218
reverse transcriptase
205
proteasome
201
calcineurin
185
phosphatidylinositol 3-kinase
166
IKK
157
catalase
150
superoxide dismutase
137
ACS
137
lactate dehydrogenase
134
chloramphenicol acetyltransferase
117
PARP
115
CYP3A4
104
NQO1
98
GSK
97
AMP-activated protein kinase
92
AMPK
89
NO synthase
88
collagenase
86
peroxidase
85
transcriptase
83
phospholipase C
81
caspase-9
80
phosphoinositide 3-kinase
76
adenylate cyclase
75
cdc2
72
DNase
71
prostate-specific antigen
69
thrombin
68
phosphodiesterase
63
NADPH oxidase
59
caspase-8
58
beta-glucuronidase
56
P-glycoprotein
55
heme oxygenase
54
DNA methyltransferase
54
tyrosine hydroxylase
53
aspartate aminotransferase
52
ribonuclease
51
ribonuclease
51
NADPH oxidase
49
DNA polymerase
49
alanine aminotransferase
48
endonuclease
48
MAP
48
AMPK
47
caspase-1
46
MEKK1
45
trypsin
45
S1 nuclease
43
creatine kinase
43
topoisomerase
43
renin
41
NOS
41
phosphoenolpyruvate carboxykinase
40
APC
40
GAS
40
topoisomerase
39
pyruvate kinase
39
aequorin
38
apyrase
36
phosphoenolpyruvate carboxykinase
35
phosphoenolpyruvate carboxykinase
35
protein phosphatase 2A
35
more...
Compound
DNA
5793
Dec
2608
MTT
1247
oxygen
1092
ATP
1081
glucose
972
cAMP
866
calcium
677
TNF
628
Clin
617
acetate
508
MDA
493
phosphate
440
water
427
AMP
361
tyrosine
356
COS
353
sodium
351
bromide
339
retinoic acid
336
lysine
309
nitric oxide
307
cysteine
264
arginine
255
serine
253
hydrogen
246
PEG
236
THP
230
THP
230
zinc
229
MEK
211
ethanol
205
iron
201
TNM
191
aldehyde
188
sulfate
181
aldehyde
180
ADP
180
PEG
173
alanine
171
tryptophan
170
ADP
167
leucine
165
ADP
165
PEI
157
PEI
157
FMN
151
NAD
151
PMA
148
ICI
145
galactose
144
His
143
methionine
141
salt
140
iodine
136
threonine
135
PMA
135
nitrogen
130
NAD
129
ACS
128
ACS
127
vitamin D
127
Insulin
127
DDP
123
NADH
123
H2O2
123
GSH
113
GSH
113
glutamate
109
NH2
105
Estrogen
103
Estrogen
96
FMNH
92
Vimentin
88
ATF
88
urea
87
PGE
85
potassium
85
Cardiol
84
Phe
82
more...