Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.14.13.97 (CYP3A4)
6,365 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein CYP3A4 0.999 CYP2C9 0.092 CYP1A2 0.082 CYP2D6 0.079 CYP2C19 0.074 CYP3A5 0.072 CYP2B6 0.064 CYP2C8 0.044 CYP3A 0.039 cytochrome P450 0.035 CYP3A7 0.021 CYP2E1 0.021 CYP2A6 0.021 CYP 0.015 P450 0.013 pregnane X receptor 0.012 CYP1A1 0.008 PXR 0.004 CYP2C 0.004 Cytochrome P450 0.004 CYP2C18 0.003 CYP3A43 0.003 constitutive androstane receptor 0.003 P-glycoprotein 0.003 ABCB1 0.002 UGT1A1 0.002 UGT2B7 0.002 CYP1B1 0.002 cytochrome P450 CYP3A4 0.001 microsomal 0.001 CYP4A11 0.001 cytochrome 0.001 CYP2J2 0.001 NR1I2 0.001 2C18 0.001 UGT1A4 0.001 FMO3 0.001 OATP1B1 0.001 UGT1A9 0.001 xenobiotic 0.001 UGT1A3 0.001 OATP1B3 0.001 SLCO1B1 0.001 P-gp 0.001 MDR1 0.001 1A1 0.001 NADPH 0.001 CYP4F2 0.001 UGT1A6 0.001 CYP2B 0.001 ABCC2 0.000 UGT 0.000 FMO1 0.000 mephenytoin 4'-hydroxylase 0.000 CYP4F12 0.000 CYP2D 0.000 NR1I3 0.000 CYP4B1 0.000 UDP-glucuronosyltransferase 0.000 organic anion transporting polypeptide 0.000 CYP2F1 0.000 OATP2B1 0.000 CYP2A 0.000 CYP3 0.000 CAR 0.000 glucuronosyltransferase 0.000 UBC7 0.000 SLCO1B3 0.000 cytochrome P-450 0.000 CYP2A13 0.000 CYP24A1 0.000 DP97 0.000 BCRP 0.000 cytochrome P450 3A7 0.000 ABCG2 0.000 flavin-containing monooxygenase 0.000 FMO5 0.000 CYP2E 0.000 UGT2B15 0.000 CYP2R1 0.000 more...

Disease CYP3A4-V 0.000 Drug-Food Interaction 0.000 Subacute hepatic failure 0.000 Therapy-related acute myeloid leukemia and myelodysplastic syndrome 0.000 NAME 0.000 Secondarily generalized seizures 0.000 hepatocellular carcinoma 0.000 renal impairment 0.000 Acute myopathy 0.000 BFNC 0.000 cancer 0.000 Hepatic impairment 0.000 HIV 0.000 GSH 0.000 MCL 0.000 torsades de pointes 0.000 dermographia 0.000 metastatic adrenocortical carcinoma 0.000 myopathy 0.000 breast cancer 0.000 Duodenum 0.000 Duodenum 0.000 Gingival hyperplasia 0.000 prostate cancer 0.000 Opioid Withdrawal 0.000 Hepatotoxicity 0.000 hypercholesterolemia 0.000 sigmoiditis 0.000 AD3 0.000 HPC1 0.000 lymphoblastoma 0.000 hepatitis C 0.000 immunodeficiency 0.000 carcinogenesis 0.000 dependent personality disorder 0.000 Diffuse panbronchiolitis 0.000 hypertension 0.000 neutropenia 0.000 CHEST 0.000 cholestasis 0.000 vascular ischemia 0.000 Opioid use disorder 0.000 mantle cell lymphoma 0.000 NPC 0.000 MCF 0.000 NS3 0.000 NNH 0.000 EIN 0.000 Lennox-Gastaut syndrome 0.000 HBD 0.000 APOA1 0.000 chronic myeloid leukemia 0.000 HRD 0.000 polydrug abuse 0.000 Chronic migraine 0.000 hypopharyngeal squamous cell carcinoma 0.000 liver disease 0.000 melanosis coli 0.000 non-small cell lung cancer 0.000 Demented 0.000 rash 0.000 Lennox-Gastaut syndrome 0.000 fatty liver 0.000 erectile dysfunction 0.000 schizophrenia 0.000 tumor 0.000 SAR 0.000 Cushing's syndrome 0.000 adrenalitis 0.000 bipolar depression 0.000 cirrhosis 0.000 hand-foot syndrome 0.000 Vascular dementia 0.000 epilepsy 0.000 DHD 0.000 DHD 0.000 Stevens-Johnson syndrome 0.000 gliosarcoma 0.000 AML/MDS 0.000 THC 0.000 more...

Symptom nausea 0.000 Severe diarrhea 0.000 diarrhea 0.000 Visual disturbances 0.000 insomnia 0.000 asthenia 0.000 vomiting 0.000 nausea and vomiting 0.000 sleepiness 0.000 dizziness 0.000 headache 0.000 nasal congestion 0.000 peri-menopausal 0.000 constipation 0.000 myalgia 0.000 Cushingoid 0.000 Cushingoid 0.000 abdominal cramps 0.000 ACHE 0.000 pain 0.000 dry skin 0.000 flushing 0.000 periorbital edema 0.000 menopausal symptoms 0.000 Postoperative nausea and vomiting 0.000 breakthrough pain 0.000 hot flashes 0.000 seizures 0.000 syncopal episodes 0.000 lightheadedness 0.000 leg edema 0.000 chronic back pain 0.000 cancer pain 0.000 analgesia 0.000 fatigue 0.000 angina 0.000 blurred vision 0.000 tremor 0.000 decreased appetite 0.000 anesthesia 0.000 muscle stiffness 0.000 hot flushes 0.000 bitter taste 0.000 weakness 0.000 skin damage 0.000 sciatica 0.000 despair 0.000 acidity 0.000 abdominal discomfort 0.000 acute pain 0.000 incoordination 0.000 abdominal pain 0.000 twitching 0.000 skin irritation 0.000 dysuria 0.000 splenomegaly 0.000 HSA 0.000 polyuria 0.000 vertigo 0.000 arthralgia 0.000 exertional dyspnea 0.000 memory loss 0.000 cough 0.000 hemiplegia 0.000 pelvic pain 0.000 syncope 0.000 paresthesia 0.000 numbness 0.000 shortness of breath 0.000 back pain 0.000 cachexia 0.000 anorexia 0.000 spasticity 0.000 tinnitus 0.000 ataxia 0.000 spasm 0.000 dystonia 0.000 discomfort 0.000 discomfort 0.000 overweight 0.000 more...

Drug Ketoconazole 0.001 Aprepitant 0.000 Tazofelone 0.000 Capravirine 0.000 Omeprazole 0.000 Sulfaphenazole 0.000 Posicor 0.000 Entocort EC 0.000 Lurasidone hydrochloride 0.000 Hectorol 0.000 Oxantel pamoate 0.000 Exatecan mesylate 0.000 Nalfurafine hydrochloride 0.000 Clopidogrel 0.000 Tacrolimus 0.000 Carbazeran 0.000 Etravirine 0.000 Avasimibe 0.000 AG-EE 388 ZW 0.000 Itraconazole 0.000 Netupitant 0.000 Cerivastatin sodium 0.000 Serzone 0.000 Stiripentol 0.000 Fosamprenavir 0.000 caffeine 0.000 Relpax 0.000 Cerivastatin sodium 0.000 Midostaurin 0.000 Ezlopitant 0.000 Rifalazil 0.000 Zedoary 0.000 Flexeril 0.000 Clast 0.000 Tirilazad mesylate 0.000 Istradefylline 0.000 Pantoprazole sodium 0.000 Propulsid 0.000 Glafenine 0.000 Tirilazad mesylate 0.000 Axitinib 0.000 Troglitazone 0.000 Bosutinib 0.000 Elvitegravir 0.000 Uncaria hook 0.000 Fluvoxamine maleate 0.000 Ebastine 0.000 Almotriptan 0.000 Simvastatin 0.000 Roquinimex 0.000 Lonafarnib 0.000 Azelastine hydrochloride 0.000 Romet 0.000 Fluconazole 0.000 ATV 0.000 Domperidone 0.000 Dronedarone 0.000 Desvenlafaxine succinate 0.000 Bextra 0.000 TMC114 0.000 Bosentan 0.000 Medazepam 0.000 Bosentan 0.000 Maraviroc 0.000 Hyperforin 0.000 Galantamine hydrobromide 0.000 Iloperidone 0.000 Eletriptan 0.000 DB289 0.000 Rifater 0.000 Alosetron 0.000 Rifater 0.000 Almotriptan 0.000 Fluvoxamine maleate 0.000 Imidafenacin 0.000 Mirtazapine 0.000 Gestodene 0.000 Tofisopam 0.000 Gemfibrozil 0.000 Loratadine 0.000 more...

Enzyme CYP3A4 1.000 6beta-hydroxylase 0.003 P-glycoprotein 0.003 UDP-glucuronosyltransferase 0.001 flavin-containing monooxygenase 0.001 quinine 3-hydroxylase 0.000 CYP27A1 0.000 demethylase 0.000 aldehyde oxidase 0.000 microsomal epoxide hydrolase 0.000 carboxylesterase 0.000 CYP46A1 0.000 N,O-acetyltransferase 0.000 CYP7A1 0.000 luciferase 0.000 CYP8B1 0.000 thiopurine methyltransferase 0.000 CYP39A1 0.000 soluble epoxide hydrolase 0.000 reverse transcriptase 0.000 aldehyde dehydrogenase 0.000 4-nitrophenol hydroxylase 0.000 glutathione S-transferase 0.000 MDR 0.000 CPT 0.000 aminocarboxymuconate-semialdehyde decarboxylase 0.000 carbonyl reductase 0.000 CPT 0.000 tyrosine aminotransferase 0.000 alanine aminotransferase 0.000 GK2 0.000 cholesterol 25-hydroxylase 0.000 CYP7B1 0.000 CPT 0.000 CPR 0.000 AST 0.000 aspartate aminotransferase 0.000 lanosterol 14alpha-demethylase 0.000 HIV-1 protease 0.000 PST 0.000 calcineurin 0.000 NQO1 0.000 acetylcholinesterase 0.000 phosphodiesterase 0.000 dihydropyrimidine dehydrogenase 0.000 ERK 0.000 LTA4 hydrolase 0.000 dipeptidyl peptidase IV 0.000 dihydropyrimidine dehydrogenase 0.000 shikimate dehydrogenase 0.000 cholinesterase 0.000 glycine amidinotransferase 0.000 NAT 0.000 squalene epoxidase 0.000 CPM 0.000 SNO 0.000 3-hydroxy-3-methylglutaryl-CoA reductase 0.000 aryl hydrocarbon hydroxylase 0.000 N-acetyltransferase 0.000 cruzipain 0.000 ornithine transcarbamylase 0.000 AGT 0.000 arylsulfatase 0.000 DMT 0.000 aldehyde dehydrogenase 0.000 aldehyde dehydrogenase 0.000 sucrase-isomaltase 0.000 alcohol dehydrogenase 0.000 aldehyde dehydrogenase 0.000 TGT 0.000 3-hydroxy-3-methylglutaryl coenzyme A reductase 0.000 thromboplastin 0.000 catalase 0.000 thromboxane synthase 0.000 1-hydroxylase 0.000 ADH3 0.000 CCS 0.000 paraoxonase 0.000 monoamine oxidase 0.000 succinic semialdehyde dehydrogenase 0.000 more...

Compound Ketoconazole 0.001 CITCO 0.001 Troleandomycin 0.001 NADPH 0.001 NADPH 0.001 Ritonavir 0.000 Diabetol 0.000 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde 0.000 Midazolam 0.000 Rifampicin 0.000 Pregnane 0.000 2-chloro-N-(2,6-diethylphenyl)acetamide 0.000 Datiscetin 0.000 4-(4-chlorobenzyl)pyridine 0.000 Rutaevin 0.000 Neoastilbin 0.000 Quinidine 0.000 Omeprazole 0.000 imidazo[2,1-b][1,3]thiazole-5-carbaldehyde 0.000 Fluvoxamine 0.000 TTMS 0.000 Bergaptol 0.000 1,3-oxazolidine-2,4-dione 0.000 Dextromethorphan 0.000 2,5-dibenzylidenecyclopentanone 0.000 Grandisin 0.000 Isophosphoramide mustard 0.000 Repaglinide 0.000 Amprenavir 0.000 Cerivastatin 0.000 5-aminopentanoic acid 0.000 epsilon-Viniferin 0.000 Auriculasin 0.000 Sophoranone 0.000 dibenzo[a,j]acridine 0.000 Ellipticine 0.000 UDP 0.000 Chlorzoxazone 0.000 Voriconazole 0.000 Orphenadrine 0.000 2,6-dibenzylidenecyclohexanone 0.000 C19H18O3 0.000 2-hydroxy-4-methoxybenzoic acid 0.000 C19H18O3 0.000 C19H18O3 0.000 C19H18O3 0.000 C19H18O3 0.000 2,2-diphenylbutanamide 0.000 C19H18O3 0.000 C19H18O3 0.000 C19H18O3 0.000 C19H18O3 0.000 C19H18O3 0.000 C19H18O3 0.000 C19H18O3 0.000 C19H18O3 0.000 C19H18O3 0.000 C19H18O3 0.000 C5H11NO 0.000 C19H18O3 0.000 methyl diethyldithiocarbamate 0.000 3,3-diphenylpyrrolidine 0.000 Methadone 0.000 Delavirdine 0.000 SN-38 0.000 aflatoxin B1 0.000 Hellebrigenin 0.000 Xanthotoxol 0.000 1-Methylxanthine 0.000 Caulophylline 0.000 C19H18O3 0.000 Cephaeline 0.000 C19H18O3 0.000 alpha-Naphthoflavone 0.000 alpha-Naphthoflavone 0.000 alpha-Naphthoflavone 0.000 Nefazodone 0.000 Dictamnine 0.000 4-Ipomeanol 0.000 Dinactin 0.000 more...

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