Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.14.13.97 (CYP3A4)
6,365 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein CYP3A4 6360 cytochrome P450 2379 CYP1A2 1440 CYP2D6 1413 CYP2C9 1298 CYP2C19 1130 P450 1024 CYP3A 920 CYP2B6 768 CYP3A5 724 CYP2E1 645 CYP 606 CYP2C8 533 microsomal 513 CYP1A1 471 P-glycoprotein 462 cytochrome 411 Sep 410 CYP2A6 400 pregnane X receptor 354 NADPH 304 Mol 257 Cytochrome P450 232 xenobiotic 222 ABCB1 192 CYP3A7 185 PXR 141 cytochrome P-450 134 albumin 131 constitutive androstane receptor 130 UGT1A1 126 MDR1 126 CYP1B1 125 CYP2C 122 reductase 119 P-gp 102 1A1 91 nuclear receptor 91 gut 85 UGT2B7 83 more...

Disease cancer 423 HIV 154 hepatocellular carcinoma 146 tumor 134 breast cancer 108 hypertension 89 GSH 72 diabetes 66 NAME 64 prostate cancer 61 immunodeficiency 60 carcinogenesis 57 depression 47 hepatitis C 42 schizophrenia 40 renal impairment 40 epilepsy 38 lung cancer 35 Alzheimer's disease 33 type 2 diabetes 32 MCF 32 cirrhosis 31 myopathy 31 tuberculosis 30 hypercholesterolemia 30 liver disease 30 adenocarcinoma 28 stroke 27 neutropenia 27 malaria 25 non-small cell lung cancer 25 AIDS 25 chronic myeloid leukemia 24 asthma 22 rheumatoid arthritis 22 rash 21 ovarian cancer 21 obesity 20 acute myeloid leukemia 19 leukemia 19 more...

Symptom pain 64 diarrhea 49 nausea 44 headache 36 vomiting 30 seizures 25 sleepiness 18 anesthesia 18 insomnia 17 nausea and vomiting 16 dizziness 15 fatigue 15 constipation 14 myalgia 11 analgesia 11 weakness 9 angina 9 flushing 9 asthenia 8 abdominal pain 7 tremor 7 acidity 5 menopausal symptoms 4 cough 4 nasal congestion 4 dry skin 3 splenomegaly 3 cancer pain 3 blurred vision 2 anorexia 2 dyspnea 2 discomfort 2 vertigo 2 overweight 2 syncope 2 arthralgia 2 hot flashes 2 ataxia 2 discomfort 2 abdominal cramps 2 more...

Drug caffeine 92 Ketoconazole 89 Monit 45 Tacrolimus 37 Omeprazole 33 Itraconazole 32 Clopidogrel 30 lysine 19 ABC 19 Simvastatin 19 Cardiovasc 18 Fluconazole 16 Glutathione 15 ADR 14 Docetaxel 14 Aprepitant 14 CPT-11 14 Portal 13 vitamin E 13 Imatinib 12 Glycyrrhiza 11 Leaf 11 ROC 11 Gefitinib 11 Troglitazone 11 Domperidone 11 Fentanyl 9 Erlotinib 9 Irinotecan 9 Phenytoin 9 ROS 9 CTX 8 ATV 8 EE2 8 Bosentan 8 CPR 8 Taxol 8 Bosentan 8 MAP 8 Cimetidine 7 more...

Enzyme CYP3A4 6365 P-glycoprotein 462 UDP-glucuronosyltransferase 116 luciferase 104 reverse transcriptase 75 demethylase 65 flavin-containing monooxygenase 60 glutathione S-transferase 54 ERK 53 6beta-hydroxylase 49 alanine aminotransferase 48 aspartate aminotransferase 36 carboxylesterase 33 acetylcholinesterase 31 catalase 29 aldehyde dehydrogenase 27 calcineurin 25 phosphodiesterase 24 MDR 23 ATPase 23 focal adhesion kinase 21 CYP27A1 21 aldehyde oxidase 20 soluble epoxide hydrolase 20 microsomal epoxide hydrolase 19 AST 19 CPR 18 protein kinase 17 CPT 17 CPT 17 CPT 17 superoxide dismutase 17 cholinesterase 17 CYP7A1 17 mitogen-activated protein kinase 16 renin 16 thromboplastin 14 ACS 14 NQO1 14 proteasome 13 more...

Compound Clin 648 Dec 460 NADPH 304 NADPH 304 DNA 237 Diabetol 164 water 136 caffeine 92 oxygen 90 Ketoconazole 89 GSH 85 GSH 85 uridine 68 glucose 67 urea 67 hydrogen 65 vitamin D 63 Rifampicin 63 UDP 61 phosphate 61 sodium 60 iron 57 ethanol 55 nitrogen 55 sulfate 53 Midazolam 48 aflatoxin B1 48 calcium 48 cysteine 45 pyridine 44 FK506 43 acetonitrile 42 APAP 40 methanol 37 acetate 35 Ritonavir 34 Omeprazole 33 DMSO 33 MTT 32 creatinine 31 more...

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