Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.14.13.97 (CYP3A4)
6,365 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein CYP3A4 6360 cytochrome P450 2379 CYP1A2 1440 CYP2D6 1413 CYP2C9 1298 CYP2C19 1130 P450 1024 CYP3A 920 CYP2B6 768 CYP3A5 724 CYP2E1 645 CYP 606 CYP2C8 533 microsomal 513 CYP1A1 471 P-glycoprotein 462 cytochrome 411 Sep 410 CYP2A6 400 pregnane X receptor 354 more...

Disease cancer 423 HIV 154 hepatocellular carcinoma 146 tumor 134 breast cancer 108 hypertension 89 GSH 72 diabetes 66 NAME 64 prostate cancer 61 immunodeficiency 60 carcinogenesis 57 depression 47 hepatitis C 42 renal impairment 40 schizophrenia 40 epilepsy 38 lung cancer 35 Alzheimer's disease 33 type 2 diabetes 32 more...

Symptom pain 64 diarrhea 49 nausea 44 headache 36 vomiting 30 seizures 25 sleepiness 18 anesthesia 18 insomnia 17 nausea and vomiting 16 fatigue 15 dizziness 15 constipation 14 analgesia 11 myalgia 11 flushing 9 weakness 9 angina 9 asthenia 8 tremor 7 more...

Drug caffeine 92 Ketoconazole 89 Monit 45 Tacrolimus 37 Omeprazole 33 Itraconazole 32 Clopidogrel 30 lysine 19 Simvastatin 19 ABC 19 Cardiovasc 18 Fluconazole 16 Glutathione 15 Aprepitant 14 Docetaxel 14 ADR 14 CPT-11 14 vitamin E 13 Portal 13 Imatinib 12 more...

Enzyme CYP3A4 6365 P-glycoprotein 462 UDP-glucuronosyltransferase 116 luciferase 104 reverse transcriptase 75 demethylase 65 flavin-containing monooxygenase 60 glutathione S-transferase 54 ERK 53 6beta-hydroxylase 49 alanine aminotransferase 48 aspartate aminotransferase 36 carboxylesterase 33 acetylcholinesterase 31 catalase 29 aldehyde dehydrogenase 27 calcineurin 25 phosphodiesterase 24 MDR 23 ATPase 23 more...

Compound Clin 648 Dec 460 NADPH 304 NADPH 304 DNA 237 Diabetol 164 water 136 caffeine 92 oxygen 90 Ketoconazole 89 GSH 85 GSH 85 uridine 68 urea 67 glucose 67 hydrogen 65 vitamin D 63 Rifampicin 63 phosphate 61 UDP 61 more...

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