Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.13.39 (NO synthase)
15,778 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
nitric oxide synthase 14318
lipopolysaccharide 1523
Sep 1193
cytokine 862
tumor necrosis factor 780
Mol 740
inducible nitric oxide synthase 640
NADPH 637
guanylate cyclase 627
cyclooxygenase 545
LPS 508
superoxide dismutase 482
eNOS 449
IFN-gamma 445
neuronal nitric oxide synthase 429
TNF 415
interferon-gamma 406
cyclooxygenase-2 401
calmodulin 398
insulin 394
ATP 393
bradykinin 343
soluble guanylyl cyclase 327
IL-6 323
angiotensin II 317
TNF-alpha 316
A-I 313
p38 283
guanylyl cyclase 249
interferon 246
diaphorase 245
catalase 245
p65 240
vascular endothelium 230
hemoglobin 221
IFN 207
phosphodiesterase 202
endothelin-1 196
heme oxygenase-1 195
NMDA receptor 195
COX-2 182
caspase-3 182
substance P 178
vascular endothelial growth factor 176
IL-10 174
renin 166
SIN 162
mitogen-activated protein 156
Ang II 155
interleukin-6 154
myeloperoxidase 154
collagen 153
reductase 153
ERK1 147
PKG 143
gut 141
tumor necrosis factor alpha 140
NOS2 139
MAPK 138
inducible form 138
NO3 131
extracellular signal-regulated kinase 129
GSH 126
xanthine oxidase 124
SOD 122
phosphatidylinositol 3-kinase 122
IL-1 121
olfactory 119
tyrosine hydroxylase 119
IL-1 beta 117
calcitonin 115
SNAP 112
constitutive nitric oxide synthase 111
cytochrome c 110
TLR4 108
DAF 107
ATPase 107
polypeptide 105
tyrosine kinase 105
IL-4 104
more...
Disease
NAME 2488
hypertension 1083
ischemia 596
diabetes 502
atherosclerosis 372
tumor 306
cancer 300
sepsis 263
sepsis 257
cardiovascular disease 229
stroke 207
depression 171
heart failure 164
pulmonary hypertension 146
cerebral ischemia 134
Alzheimer's disease 127
GSH 126
obesity 121
Endothelial dysfunction 107
asthma 106
vascular disease 103
myocardial ischemia 102
hyperglycemia 101
hypercholesterolemia 98
myocardial infarction 86
Parkinson's disease 86
type 2 diabetes 84
colitis 80
carcinogenesis 76
Mycobacterium 70
renal disease 69
cold 69
arthritis 67
tumor growth 63
pertussis 62
preeclampsia 62
erectile dysfunction 61
proteinuria 58
multiple sclerosis 58
coronary artery disease 57
metabolic syndrome 55
infectious diseases 55
Evans 54
cirrhosis 54
endotoxic shock 54
rheumatoid arthritis 54
renal failure 53
ventricular hypertrophy 52
tuberculosis 52
ATM 52
inflammatory bowel disease 51
Blocking 51
encephalomyelitis 49
virus infection 48
neuroblastoma 47
Huntington's disease 47
type 1 diabetes 46
malaria 45
SEM 43
plaque 42
Infection 39
essential hypertension 39
epilepsy 38
uterus 38
leishmaniasis 38
chronic renal failure 38
ulcerative colitis 38
migraine 37
osteoarthritis 37
melanoma 37
congestive heart failure 36
glioma 35
adenocarcinoma 35
pulmonary edema 34
glomerulonephritis 32
hepatocellular carcinoma 32
tumorigenesis 30
fits 30
pneumonia 30
varices 30
more...
Symptom
pain 143
seizures 98
anesthesia 90
hypothermia 40
hyperoxia 39
diarrhea 34
hypercapnia 34
collapse 23
headache 20
analgesia 19
respiratory distress 19
functional recovery 18
fatigue 16
starvation 13
spasm 12
angina 11
cachexia 11
exhaustion 9
tremor 9
cough 7
acute stress 7
splenomegaly 6
anorexia 6
constipation 6
polyuria 6
erythema 6
thinning 6
low back pain 5
ataxia 5
overweight 4
syncope 4
weakness 4
arthralgia 4
myalgia 4
vomiting 4
chest pain 4
hypocapnia 4
twitching 3
clonus 3
dizziness 3
sleepiness 3
flushing 3
spasticity 3
distraction 3
insomnia 3
Deafferentation 3
acidity 3
dystonia 3
neuralgia 3
acute pain 3
polydipsia 2
neck pain 2
discomfort 2
eds 2
agitation 2
Decreased activity 2
Gasping 2
HSA 2
memory loss 2
abnormal gait 2
tonic seizure 2
nausea 2
Neuropathic pain 2
incoordination 2
Ill 2
discomfort 2
back pain 2
dyspnea 2
Macula 2
abdominal pain 2
orofacial pain 2
rundown 2
myoclonus 2
skin damage 2
general problem 1
ENT 1
tenesmus 1
cerebellar ataxia 1
exertional dyspnea 1
muscle stiffness 1
more...
Drug
IFN-gamma 442
Cardiovasc 209
Nitric Oxide 208
lysine 163
BH4 126
Indomethacin 85
nitroglycerin 82
Sodium nitroprusside 74
FAD 72
ROS 67
Aminoguanidine 65
ascorbate 61
ICI 58
MAP 57
Angiotensin II 56
Methylene blue 52
IL-2 51
ETA 46
NADH 44
CSF 38
Nephron 33
vitamin E 31
Dermatol 26
Heme 26
caffeine 25
IFN-beta 24
Histamine 23
Gel 23
Ethanol 21
EE2 19
Simvastatin 18
7-Nitroindazole 16
Forskolin 15
Captopril 15
CTX 14
Nebivolol 12
Ringer's solution 11
Vitamin E 11
Atropine 10
Glutathione 10
EPA 10
Pravastatin 9
Estrogens 9
Asthma 9
Kainic acid 9
Molsidomine 8
ampicillin 8
Bosentan 8
Bosentan 8
Portal 8
Fructose 8
Nephron 7
Viagra 7
PCP 7
Viagra 7
Glucagon 6
Ginseng 6
Clonidine 6
Dial 6
CaCl2 6
CaCl2 6
IL-1ra 6
p75 6
CaCl2 6
ETS 5
Salicylate 5
citric acid 5
Troglitazone 5
CCL 5
THF 5
Leaf 5
Cilostazol 5
Phentolamine 5
Valsartan 5
Rosuvastatin 5
CTX 5
Ouabain 5
CTX 5
Secretin 4
Iloprost 4
more...
Enzyme
NO synthase 15778
NADPH-diaphorase 1564
NOS 1113
guanylate cyclase 879
mitogen-activated protein kinase 597
superoxide dismutase 545
protein kinase 498
NADPH oxidase 326
protein kinase C 274
diaphorase 267
arginase 266
NADPH oxidase 262
catalase 261
NQO1 256
diaphorase 245
peroxidase 205
phosphodiesterase 203
renin 166
ERK 147
caspase-3 144
PKG 143
xanthine oxidase 137
phosphatidylinositol 3-kinase 122
heme oxygenase 116
focal adhesion kinase 115
tyrosine hydroxylase 115
ATPase 110
glutathione peroxidase 95
AMP-activated protein kinase 91
MEK 88
luciferase 88
lactate dehydrogenase 84
reverse transcriptase 81
thrombin 79
ACE 78
phospholipase C 73
cytochrome oxidase 70
choline acetyltransferase 65
IKK 64
acetylcholinesterase 63
GTP cyclohydrolase I 62
nitrate reductase 59
nitrate reductase 58
nitrate reductase 58
nitrate reductase 58
nitrate reductase 58
nitrate reductase 58
alanine aminotransferase 55
adenylate cyclase 53
dimethylarginine dimethylaminohydrolase 53
calcineurin 51
phospholipase A2 50
phosphoinositide 3-kinase 49
AMPK 49
MAP 47
PARP 41
proteasome 38
ornithine decarboxylase 34
RNA polymerase 34
lipoxygenase 34
aspartate aminotransferase 34
alkaline phosphatase 32
PDE 30
glyceraldehyde-3-phosphate dehydrogenase 29
complex I 29
beta-galactosidase 28
RNase 28
argininosuccinate synthetase 28
RNase 28
glutathione S-transferase 27
creatine kinase 26
transcriptase 26
nitrite reductase 25
trypsin 25
nitrite reductase 25
nitrite reductase 25
CPR 25
glutathione reductase 23
AMPK 23
CaMKII 22
more...
Compound
nitric oxide 10943
arginine 5920
cGMP 1492
oxygen 1360
sodium 1301
calcium 1197
Dec 1188
nitrate 742
NADPH 638
NADPH 637
DNA 607
water 518
Clin 492
glucose 438
TNF 415
ATP 394
glutamate 348
nitrogen 337
phosphate 307
tyrosine 270
cAMP 261
CIT 258
salt 249
acetate 247
nicotinamide 236
GMP 230
ACh 227
potassium 211
iron 197
hydrogen 194
CO2 191
cysteine 187
noradrenaline 184
lysine 184
NO3 183
prostacyclin 173
NMDA 172
PGE 172
ornithine 170
ornithine 170
ornithine 170
ornithine 170
ornithine 170
ethanol 151
serine 132
GSH 131
GSH 131
urea 124
Cardiol 117
ADP 110
H2O2 106
creatinine 102
PGE2 102
Neuronal 100
Nitrite 100
Nitrite 100
Ang II 98
ADP 96
ADP 96
GABA 94
GABA 94
diacetate 94
AMP 87
Nitro-L-arginine 87
threonine 86
sulfate 82
Angiotensin II 82
FMN 79
superoxide radical 79
Indomethacin 78
5-HT 77
N-acetylcysteine 75
Phe 75
zinc 75
alanine 74
FAD 72
galactose 72
Insulin 72
8-Br-cGMP 67
methionine 66
more...