Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.13.39 (NO synthase)
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Human Gene/Protein
CYP51A1 protein 11.0
HSD40 11.0
transforming growth factor, beta 2 10.0
SLC8A1 protein 10.0
PRKG1 protein 10.0
nitric oxide synthase 9.9
ra-a47 9.7
sONE 9.4
TBC1D8B 9.4
Erbb2 interacting protein 9.4
clathrin-associated/assembly/adaptor protein, small 3 9.4
NOS III 9.2
GCH1 protein 9.0
mimitin 9.0
GUCY1B3 8.9
Constitutive NOS 8.8
H4B 8.7
protein phosphatase inhibitor 2 8.7
kinesin light chain 4 8.7
DDAH-1 8.5
soluble guanylyl cyclase 8.5
NBP1 8.4
NOS1 8.4
G-protein coupled receptor 15 8.4
selenoprotein O 8.4
Interleukin-21 receptor 8.4
constitutive nitric oxide synthase 8.4
ABHD4 8.3
NOS-1 8.3
mitogenic oxidase 8.2
NOS3 8.1
NOS2 8.1
Diaphorase 8.1
diaphorase 8.0
inducible form 8.0
arginase II 8.0
DEF3 8.0
transcription factor NRF 8.0
FIN13 8.0
PR65A 8.0
more...
Disease
Brisket disease 9.4
Acute nephropathy 9.4
Renal parenchymal disease 9.0
mild intolerance 9.0
Neuroglycopenia 9.0
Renal parenchymal hypertension 9.0
NINA 8.7
Intestinal mass 8.7
NAME 8.6
vascular hypoxia 8.0
Irreversible pulpitis 7.8
cerebral ischemia/hypoxia 7.5
Gastrointestinal inflammation 7.5
Acute peritonitis 7.5
dual personality 7.3
Primary Raynaud's phenomenon 7.2
Distal colitis 7.2
Chronic iron overload 7.1
Secondary pulmonary hypertension 7.0
Chinese restaurant syndrome 7.0
Endothelial dysfunction 6.8
IMD1 6.8
Total colonic aganglionosis 6.8
Radiation Syndrome 6.7
PAPA 6.6
vitamin B deficiency 6.5
Morphine dependence 6.5
AD10 6.3
disturbed memory 6.3
endotoxic shock 6.3
Renal pelvis 6.2
Renal pelvis 6.2
Manganese deficiency 6.2
Corneal infection 6.1
Leukostasis 6.1
Border Disease 6.1
Aspiration pneumonitis 6.1
vascular dilation 6.0
Imu 6.0
Drug eruption 5.9
more...
Symptom
Hyposensitivity 7.2
SYMPTOMS 7.1
Gasping 6.1
Deafferentation 5.2
abnormal reflex 5.2
Macula 5.1
situational stress 4.6
tonic seizure 4.3
cardiovascular impairment 4.2
hyperoxia 3.9
impaired motor coordination 3.4
disturbed balance 3.1
hypercapnia 3.1
ACHE 3.1
clonus 3.0
rundown 3.0
Decreased activity 2.9
non-productive cough 2.8
hypocapnia 2.3
hypothermia 2.2
loss of balance 2.2
orofacial pain 2.1
tenesmus 2.1
polyuria 2.0
cachexia 2.0
eds 1.9
sinus pressure 1.9
Anoxia 1.9
ketonuria 1.9
abnormal gait 1.8
neuralgia 1.8
spasm 1.7
asynergy 1.6
acute stress 1.6
twitching 1.6
Neuropathic pain 1.5
functional recovery 1.4
skin damage 1.4
seizures 1.3
general problem 1.2
more...
Drug
Dilazep dihydrochloride 9.4
N-Hydroxyguanidine 9.4
S-Ethylisothiourea 8.7
7-Nitroindazole 8.5
Aminoguanidine 8.3
Metastat 8.2
Verlukast 8.2
Amiloride hydrochloride 7.8
OKG 7.7
Duroquinone 7.4
BH4 7.4
Nitric Oxide 7.3
Corydalis tuber 7.3
Sodium nitroprusside 7.3
Benidipine hydrochloride 7.1
Platonin 7.1
Carperitide 7.1
Quinaprilat 6.9
Molsidomine 6.8
Norvaline 6.5
Nebivolol 6.5
Sivelestat sodium hydrate 6.4
Mangafodipir trisodium 6.4
Methylene blue 6.4
Cevimeline 6.3
L-Homoarginine 6.3
Sodium Nitroprusside 6.3
Nipradilol 6.0
Acadesine 6.0
Polaprezinc 6.0
Arfonad 6.0
Lubeluzole 6.0
Trospium chloride 5.9
CGS 13080 5.9
E5564 5.8
Acemannan 5.8
LCBF 5.8
Gabexate mesilate 5.8
Regitine 5.6
Mevastatin 5.6
more...
Enzyme
NO synthase 11.0
NADPH-diaphorase 9.7
dimethylarginine dimethylaminohydrolase 8.4
NOS 8.3
guanylate cyclase 7.7
GTP cyclohydrolase I 7.6
diaphorase 7.5
6-pyruvoyltetrahydropterin synthase 7.4
rosmarinic acid synthase 7.2
arginase 7.2
PKG 6.8
argininosuccinate lyase 6.6
steroid 11beta-hydroxylase 6.6
diaphorase 6.5
sepiapterin reductase 6.5
cyclohydrolase 6.5
EC 2.6.1.4 6.5
NQO1 6.4
carboxypeptidase S 6.4
argininosuccinate synthetase 6.4
PGE2-9-ketoreductase 6.3
hydroxylamine reductase 6.0
hydroxylamine reductase 6.0
NADPH oxidase 5.9
heme oxygenase 5.8
NADPH oxidase 5.7
LDT 5.7
glycine amidinotransferase 5.7
prostacyclin synthase 5.6
dihydroneopterin aldolase 5.4
PGE2 isomerase 5.3
biliverdin reductase 5.2
thromboxane synthase 5.2
cGMP phosphodiesterase 5.1
xanthine oxidase 5.0
carboxypeptidase D 5.0
SNO 5.0
nitrate reductase 5.0
nitrate reductase 5.0
nitrate reductase 5.0
more...
Compound
C6H13N3O3 11.0
S-Methylisothiourea sulfate 11.0
C6H13N3O3 11.0
C6H13N3O3 11.0
C6H13N3O3 11.0
Inflexin 11.0
C6H13N3O3 11.0
C6H13N3O3 11.0
C6H13N3O3 11.0
C6H13N3O3 11.0
Tetrahydroneopterin 10.0
Sinapyl alcohol 10.0
8-iso-PGF2beta 10.0
4-fluoro-2-methylphenol 10.0
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
Dilazep dihydrochloride 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
C10H18O 9.4
more...