Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.13.39 (NO synthase)
15,778 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
nitric oxide synthase 14318
lipopolysaccharide 1523
Sep 1193
cytokine 862
tumor necrosis factor 780
Mol 740
inducible nitric oxide synthase 640
NADPH 637
guanylate cyclase 627
cyclooxygenase 545
LPS 508
superoxide dismutase 482
eNOS 449
IFN-gamma 445
neuronal nitric oxide synthase 429
TNF 415
interferon-gamma 406
cyclooxygenase-2 401
calmodulin 398
insulin 394
ATP 393
bradykinin 343
soluble guanylyl cyclase 327
IL-6 323
angiotensin II 317
TNF-alpha 316
A-I 313
p38 283
guanylyl cyclase 249
interferon 246
catalase 245
diaphorase 245
p65 240
vascular endothelium 230
hemoglobin 221
IFN 207
phosphodiesterase 202
endothelin-1 196
NMDA receptor 195
heme oxygenase-1 195
more...
Disease
NAME 2488
hypertension 1083
ischemia 596
diabetes 502
atherosclerosis 372
tumor 306
cancer 300
sepsis 263
sepsis 257
cardiovascular disease 229
stroke 207
depression 171
heart failure 164
pulmonary hypertension 146
cerebral ischemia 134
Alzheimer's disease 127
GSH 126
obesity 121
Endothelial dysfunction 107
asthma 106
vascular disease 103
myocardial ischemia 102
hyperglycemia 101
hypercholesterolemia 98
Parkinson's disease 86
myocardial infarction 86
type 2 diabetes 84
colitis 80
carcinogenesis 76
Mycobacterium 70
cold 69
renal disease 69
arthritis 67
tumor growth 63
preeclampsia 62
pertussis 62
erectile dysfunction 61
proteinuria 58
multiple sclerosis 58
coronary artery disease 57
more...
Symptom
pain 143
seizures 98
anesthesia 90
hypothermia 40
hyperoxia 39
diarrhea 34
hypercapnia 34
collapse 23
headache 20
respiratory distress 19
analgesia 19
functional recovery 18
fatigue 16
starvation 13
spasm 12
angina 11
cachexia 11
tremor 9
exhaustion 9
acute stress 7
cough 7
splenomegaly 6
erythema 6
polyuria 6
constipation 6
thinning 6
anorexia 6
low back pain 5
ataxia 5
vomiting 4
weakness 4
syncope 4
overweight 4
myalgia 4
hypocapnia 4
chest pain 4
arthralgia 4
sleepiness 3
dystonia 3
acute pain 3
more...
Drug
IFN-gamma 442
Cardiovasc 209
Nitric Oxide 208
lysine 163
BH4 126
Indomethacin 85
nitroglycerin 82
Sodium nitroprusside 74
FAD 72
ROS 67
Aminoguanidine 65
ascorbate 61
ICI 58
MAP 57
Angiotensin II 56
Methylene blue 52
IL-2 51
ETA 46
NADH 44
CSF 38
Nephron 33
vitamin E 31
Heme 26
Dermatol 26
caffeine 25
IFN-beta 24
Gel 23
Histamine 23
Ethanol 21
EE2 19
Simvastatin 18
7-Nitroindazole 16
Forskolin 15
Captopril 15
CTX 14
Nebivolol 12
Ringer's solution 11
Vitamin E 11
Glutathione 10
Atropine 10
more...
Enzyme
NO synthase 15778
NADPH-diaphorase 1564
NOS 1113
guanylate cyclase 879
mitogen-activated protein kinase 597
superoxide dismutase 545
protein kinase 498
NADPH oxidase 326
protein kinase C 274
diaphorase 267
arginase 266
NADPH oxidase 262
catalase 261
NQO1 256
diaphorase 245
peroxidase 205
phosphodiesterase 203
renin 166
ERK 147
caspase-3 144
PKG 143
xanthine oxidase 137
phosphatidylinositol 3-kinase 122
heme oxygenase 116
focal adhesion kinase 115
tyrosine hydroxylase 115
ATPase 110
glutathione peroxidase 95
AMP-activated protein kinase 91
MEK 88
luciferase 88
lactate dehydrogenase 84
reverse transcriptase 81
thrombin 79
ACE 78
phospholipase C 73
cytochrome oxidase 70
choline acetyltransferase 65
IKK 64
acetylcholinesterase 63
more...
Compound
nitric oxide 10943
arginine 5920
cGMP 1492
oxygen 1360
sodium 1301
calcium 1197
Dec 1188
nitrate 742
NADPH 638
NADPH 637
DNA 607
water 518
Clin 492
glucose 438
TNF 415
ATP 394
glutamate 348
nitrogen 337
phosphate 307
tyrosine 270
cAMP 261
CIT 258
salt 249
acetate 247
nicotinamide 236
GMP 230
ACh 227
potassium 211
iron 197
hydrogen 194
CO2 191
cysteine 187
noradrenaline 184
lysine 184
NO3 183
prostacyclin 173
PGE 172
NMDA 172
ornithine 170
ornithine 170
more...