Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.13.39 (NO synthase)
 15,778 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
nitric oxide synthase 14318
lipopolysaccharide 1523
Sep 1193
cytokine 862
tumor necrosis factor 780
Mol 740
inducible nitric oxide synthase 640
NADPH 637
guanylate cyclase 627
cyclooxygenase 545
LPS 508
superoxide dismutase 482
eNOS 449
IFN-gamma 445
neuronal nitric oxide synthase 429
TNF 415
interferon-gamma 406
cyclooxygenase-2 401
calmodulin 398
insulin 394
more...
Disease
NAME 2488
hypertension 1083
ischemia 596
diabetes 502
atherosclerosis 372
tumor 306
cancer 300
sepsis 263
sepsis 257
cardiovascular disease 229
stroke 207
depression 171
heart failure 164
pulmonary hypertension 146
cerebral ischemia 134
Alzheimer's disease 127
GSH 126
obesity 121
Endothelial dysfunction 107
asthma 106
more...
Symptom
pain 143
seizures 98
anesthesia 90
hypothermia 40
hyperoxia 39
diarrhea 34
hypercapnia 34
collapse 23
headache 20
analgesia 19
respiratory distress 19
functional recovery 18
fatigue 16
starvation 13
spasm 12
angina 11
cachexia 11
tremor 9
exhaustion 9
cough 7
more...
Drug
IFN-gamma 442
Cardiovasc 209
Nitric Oxide 208
lysine 163
BH4 126
Indomethacin 85
nitroglycerin 82
Sodium nitroprusside 74
FAD 72
ROS 67
Aminoguanidine 65
ascorbate 61
ICI 58
MAP 57
Angiotensin II 56
Methylene blue 52
IL-2 51
ETA 46
NADH 44
CSF 38
more...
Enzyme
NO synthase 15778
NADPH-diaphorase 1564
NOS 1113
guanylate cyclase 879
mitogen-activated protein kinase 597
superoxide dismutase 545
protein kinase 498
NADPH oxidase 326
protein kinase C 274
diaphorase 267
arginase 266
NADPH oxidase 262
catalase 261
NQO1 256
diaphorase 245
peroxidase 205
phosphodiesterase 203
renin 166
ERK 147
caspase-3 144
more...
Compound
nitric oxide 10943
arginine 5920
cGMP 1492
oxygen 1360
sodium 1301
calcium 1197
Dec 1188
nitrate 742
NADPH 638
NADPH 637
DNA 607
water 518
Clin 492
glucose 438
TNF 415
ATP 394
glutamate 348
nitrogen 337
phosphate 307
tyrosine 270
more...