Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.14.11.27 (
histone demethylase
)
946
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
histone
455
histone H3
201
LSD1
171
Mol
103
Sep
59
JMJD2A
56
JMJD3
55
histone methyltransferase
50
KDM3A
44
histone deacetylase
43
p53
35
UTX
31
KDM5A
29
jumonji
28
KDM2B
27
androgen receptor
26
KDM6A
25
KDM5B
24
KDM2A
22
KDM4B
22
more...
Disease
cancer
257
tumor
136
tumorigenesis
69
breast cancer
60
tumor growth
31
prostate cancer
30
carcinogenesis
28
leukemia
27
tumor progression
24
acute myeloid leukemia
22
colorectal cancer
21
carcinoma
20
lung cancer
17
mental retardation
16
gastric cancer
16
mental retardation
15
obesity
13
glioblastoma
12
colon cancer
12
cold
12
more...
Symptom
starvation
6
pain
2
hypothermia
1
Scratch
1
collapse
1
seizures
1
delayed language development
1
splenomegaly
1
Drug
lysine
325
FAD
10
ascorbate
8
Dermatol
3
Cardiovasc
2
GEO
2
Retinoic acid
2
ETS
2
Parnate
2
Albumin
1
citric acid
1
CDX
1
PCP
1
THF
1
ADR
1
Flavin
1
BLM
1
ROS
1
MOF
1
9-THC
1
more...
Enzyme
histone demethylase
946
demethylase
221
GSK
20
monoamine oxidase
20
diamine oxidase
16
ERK
16
luciferase
15
histone acetyltransferase
15
DNA methyltransferase
15
RNA polymerase
13
Lys4
13
protein kinase
12
PHD
11
proteasome
9
focal adhesion kinase
9
PARP
7
mitogen-activated protein kinase
6
cdc2
5
ACS
4
alkaline phosphatase
4
more...
Compound
lysine
374
DNA
168
Histone
83
Dec
54
2-oxoglutarate
42
oxygen
26
Clin
24
iron
17
glucose
13
zinc
11
FAD
11
LSD
9
hydrogen
8
retinoic acid
8
TNF
7
formaldehyde
7
formaldehyde
7
arginine
7
leucine
6
nickel
6
more...