Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.11.2 (prolyl hydroxylase)
 1,814 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
prolyl 4-hydroxylase 0.245
proline hydroxylase 0.046
PHD2 0.026
Prolyl hydroxylase 0.026
PHD3 0.014
PHD1 0.009
lysyl hydroxylase 0.008
HIF-1alpha 0.002
PHD 0.002
Lysyl hydroxylase 0.002
EGLN3 0.002
HIF-1 0.002
collagen 0.001
MAPK organizer 1 0.001
P4HA2 0.001
P4HA3 0.001
Prolyl hydroxylase domain-containing protein 2 0.001
HPH-3 0.001
pVHL 0.001
ER lipid raft associated 1 0.001
dihydropyrimidinase-like 2 variant 0.001
Prolyl 3-hydroxylase 0.001
lysyl oxidase 0.001
EGLN2 0.001
von Hippel-Lindau tumor suppressor 0.001
P4HA1 0.001
OGFOD1 0.001
glutathione-insulin transhydrogenase 0.001
HIF-1 alpha 0.001
HPH2 0.000
protein disulfide isomerase 0.000
HIF1 0.000
EDS VI 0.000
BBAP 0.000
erythropoietin 0.000
FIH-1 0.000
disulfide isomerase 0.000
TBC1D16 0.000
transcription factor 17 0.000
FBLN5 protein 0.000
ACTIN-2 0.000
P3H2 0.000
Egl nine homolog 3 0.000
type I collagen alpha 1 chain 0.000
transmembrane protein 127 0.000
glycerol-3-phosphate dehydrogenase 1-like 0.000
P4HB 0.000
Cullin 2 0.000
P3H1 0.000
HIF2A 0.000
cartilage-associated protein 0.000
N-myc downstream-regulated gene 3 0.000
seven in absentia homolog 2 0.000
HIF-1beta 0.000
RCC4 0.000
PH4 0.000
ERp60 0.000
Deoxyhypusine hydroxylase 0.000
vascular endothelial growth factor 0.000
ERLIN1 0.000
FLNA protein 0.000
candidate tumor suppressor protein 0.000
LEPREL1 0.000
inhibitor of growth family member 4 0.000
ODD 0.000
Skp1 0.000
type I procollagen 0.000
VHL 0.000
C17orf32 0.000
SPFH1 0.000
Peptidyl-prolyl cis-trans isomerase 0.000
CCDC115 0.000
beta polypeptide 0.000
RPS23 0.000
FIH1 0.000
HA95 0.000
GKD 0.000
surfactant protein A1 0.000
Inhibitory PAS domain protein 0.000
EDHB 0.000
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Disease
Hippel 0.002
FIH 0.001
Cardiac cirrhosis 0.000
Renal anemia 0.000
erythrocytosis 0.000
EDS VI 0.000
anemia 0.000
pancreatic fibrosis 0.000
Hereditary Leiomyomatosis and Renal Cell Cancer 0.000
liver fibrosis 0.000
pulmonary fibrosis 0.000
IBD5 0.000
polycythemia 0.000
Glycerol kinase deficiency 0.000
High myopia 0.000
chronic brain syndrome 0.000
cirrhosis 0.000
ischemia 0.000
somatostatinoma 0.000
Posterior capsule opacification 0.000
disorders of iron metabolism 0.000
Acute pyelonephritis 0.000
scurvy 0.000
cancer angiogenesis 0.000
nasopharyngitis 0.000
cancer 0.000
Transient ischemia 0.000
hepatic neoplasm 0.000
tumor 0.000
Carotid body 0.000
Carotid body 0.000
Carotid body 0.000
vitamin C deficiency 0.000
tumor growth 0.000
paraganglioma 0.000
tumor progression 0.000
chronic persistent hepatitis 0.000
tumor angiogenesis 0.000
Schistosoma haematobium infection 0.000
tumorigenesis 0.000
Ehlers-Danlos syndrome 0.000
Renovascular hypertension 0.000
alcoholic hepatitis 0.000
vitamin B6 deficiency 0.000
normocytic anemia 0.000
iron deficiency 0.000
chronic active hepatitis 0.000
biliary atresia 0.000
Chronic kidney disease (CKD) 0.000
CPX 0.000
LAD2 0.000
Cirrhosis 0.000
SMC 0.000
Interstitial fibrosis 0.000
hepatocellular carcinoma 0.000
disc degeneration 0.000
Cancer cachexia 0.000
retinopathy of prematurity 0.000
hormone refractory prostate cancer 0.000
Meningioma 0.000
Meningioma 0.000
ochronosis 0.000
pulmonary hypertension 0.000
bronchopulmonary dysplasia 0.000
XPB 0.000
ST8 0.000
trophoblastic tumor 0.000
Pulmonary arterial hypertension 0.000
PDC 0.000
myotonia congenita 0.000
EBM 0.000
hyperviscosity syndrome 0.000
DBM 0.000
Renal fibrosis 0.000
acute hepatitis 0.000
liver disease 0.000
degenerative disc disease 0.000
chronic liver disease 0.000
mountain sickness 0.000
Alkaptonuria 0.000
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Symptom
Cold intolerance 0.000
hyperoxia 0.000
dysesthesia 0.000
hyperesthesia 0.000
starvation 0.000
fasciculation 0.000
respiratory distress 0.000
twitching 0.000
polydipsia 0.000
cachexia 0.000
hypotonia 0.000
polyuria 0.000
functional recovery 0.000
paresthesia 0.000
thinning 0.000
numbness 0.000
hypothermia 0.000
hypercapnia 0.000
splenomegaly 0.000
low back pain 0.000
back pain 0.000
dyspnea 0.000
acidity 0.000
tremor 0.000
nausea 0.000
diarrhea 0.000
collapse 0.000
pain 0.000
abdominal pain 0.000
fatigue 0.000
headache 0.000
anesthesia 0.000
Drug
Malotilate 0.000
ascorbate 0.000
CoCl2 0.000
CoCl2 0.000
Creosote 0.000
Silodosin 0.000
lysine 0.000
Dilantin 0.000
Deferasirox 0.000
Tranilast 0.000
Raltegravir 0.000
Desferal 0.000
Desferal 0.000
ID2 0.000
Piracetam 0.000
Rosiglitazone 0.000
ATV 0.000
Oxaliplatin 0.000
Asn 0.000
Metrizamide 0.000
Phenytoin 0.000
Triclosan 0.000
Gelfoam 0.000
OTC 0.000
Cetuximab 0.000
OTC 0.000
Nitric Oxide 0.000
Gel 0.000
Serum albumin 0.000
Angiotensin II 0.000
BLM 0.000
Heme 0.000
Prednisolone 0.000
balanced salt solution 0.000
TAC 0.000
niacin 0.000
Activin 0.000
Gelatin 0.000
Docetaxel 0.000
NADH 0.000
Dial 0.000
EPI 0.000
ROS 0.000
ACT 0.000
Silica 0.000
Alliance 0.000
Alanine 0.000
Dermatol 0.000
ADM 0.000
CSF 0.000
EE2 0.000
DNase I 0.000
Glucagon 0.000
citric acid 0.000
Albumin 0.000
G-CSF 0.000
ICI 0.000
CTX 0.000
CTX 0.000
CAM 0.000
CaCl2 0.000
CaCl2 0.000
CaCl2 0.000
Cardiovasc 0.000
PTH 0.000
MAP 0.000
ENT 0.000
ABC 0.000
nitroglycerin 0.000
Ethanol 0.000
CTX 0.000
ZnO 0.000
IFN-gamma 0.000
Enzyme
prolyl hydroxylase 0.999
galactosylhydroxylysyl glucosyltransferase 0.012
lysyl hydroxylase 0.009
prolyl 3-hydroxylase 0.003
PHD 0.002
EC 1.14.11.12 0.001
lysyl oxidase 0.001
protein disulfide-isomerase 0.001
collagen galactosyltransferase 0.001
type III procollagen 0.000
phosphopantothenoylcysteine synthetase 0.000
collagenase 0.000
deoxyhypusine hydroxylase 0.000
phosphoserine phosphatase 0.000
proline oxidase 0.000
proteasome 0.000
3-hydroxyanthranilic acid oxygenase 0.000
calpain 10 0.000
fumarase 0.000
PDK1 0.000
gamma-butyrobetaine hydroxylase 0.000
EC 2.6.1.16 0.000
PPH 0.000
succinate dehydrogenase 0.000
AlkA 0.000
3-dehydroquinate 0.000
stromelysin-3 0.000
anthocyanidin synthase 0.000
glycogenin 0.000
flavonol synthase 0.000
pepsin 0.000
deoxyhypusine synthase 0.000
oxoglutarate dehydrogenase 0.000
violaxanthin de-epoxidase 0.000
ornithine aminotransferase 0.000
homogentisate 1,2-dioxygenase 0.000
ascorbate oxidase 0.000
cinnamate 4-hydroxylase 0.000
uridine kinase 0.000
cysteine dioxygenase 0.000
formaldehyde dehydrogenase 0.000
dehydroascorbate reductase 0.000
sulfhydryl oxidase 0.000
meprin 0.000
branching enzyme 0.000
biliverdin reductase 0.000
gamma-glutamyl transpeptidase 0.000
glycerophosphate acyltransferase 0.000
UDP-glucose dehydrogenase 0.000
alpha-ketoglutarate dehydrogenase 0.000
hexokinase 0.000
Lys4 0.000
nicotinamide phosphoribosyltransferase 0.000
luciferase 0.000
caspase-7 0.000
caspase-7 0.000
histone demethylase 0.000
interstitial collagenase 0.000
phosphatidylinositol 3-kinase 0.000
thymidine phosphorylase 0.000
heme oxygenase 0.000
AMP-activated kinase 0.000
MPP 0.000
caspase-6 0.000
alkaline phosphatase 0.000
ribonucleotide reductase 0.000
isocitrate dehydrogenase 0.000
prolidase 0.000
caspase-6 0.000
N-acetylglucosaminyltransferase 0.000
ADPase 0.000
isocitrate dehydrogenase 0.000
ERK 0.000
isopeptidase 0.000
matrix metalloproteinase 2 0.000
enolase 0.000
lactate dehydrogenase 0.000
carbonic anhydrase 0.000
thymidine kinase 0.000
galactokinase 0.000
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Compound
4-hydroxyproline 0.003
4-hydroxyproline 0.003
4-hydroxyproline 0.003
4-hydroxyproline 0.003
4-hydroxyproline 0.003
4-hydroxyproline 0.003
2-oxoglutarate 0.002
ethyl 3,4-dihydroxybenzoate 0.002
Hydroxyproline 0.002
proline 0.001
Pro-Gly 0.000
Coumalic acid 0.000
Glucosylgalactosylhydroxylysine 0.000
oxygen 0.000
Collagen 0.000
Bleomycin sulfate 0.000
protocatechuate 0.000
hydroxyglutarate 0.000
iron 0.000
Mimosine 0.000
Hydroxylysine 0.000
Pimonidazole 0.000
Pimonidazole 0.000
4-methylproline 0.000
Poly ICLC 0.000
Ascorbic acid 0.000
2-Oxoglutarate 0.000
Cys-Gly 0.000
Desmosine 0.000
Sodium hydrosulfide 0.000
Tin 0.000
CCl4 0.000
Dianabol 0.000
Deoxyribose 0.000
Z-Gly-Pro 0.000
Dihydralazine 0.000
Mimosine 0.000
ABPP 0.000
Amentoflavone 0.000
R 1881 0.000
Emetine 0.000
dicarboxylic acid 0.000
4-oxobutanoic acid 0.000
Acriflavine 0.000
TET 0.000
TET 0.000
Oil Red 0.000
Aloe-emodin 0.000
2-oxoadipate 0.000
Reticulin 0.000
CPH 0.000
lysine 0.000
HMBA 0.000
Retinyl palmitate 0.000
Digitoxin 0.000
DETA 0.000
DFO 0.000
asparagine 0.000
Proline 0.000
pyridine 0.000
Hydralazine 0.000
Esculetin 0.000
DCVC 0.000
DHB 0.000
HMBA 0.000
2-methoxyethyl 0.000
cobalt 0.000
2-methoxyethyl 0.000
Temsirolimus 0.000
succinic acid 0.000
C10H8N2 0.000
8-hydroxyguanosine 0.000
Tetramethylpyrazine 0.000
Magnolol 0.000
8-quinolinol 0.000
Wogonin 0.000
4-phenylpyridine 0.000
[1,10]phenanthroline 0.000
1,2,3,6-tetrahydropyridine 0.000
1,2,3,6-tetrahydropyridine 0.000
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