EC:1.14.11.2 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: EC:1.14.11.2 (prolyl hydroxylase)
1,814 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
collagen	562
prolyl 4-hydroxylase	447
PHD2	150
Mol	128
Sep	112
erythropoietin	109
vascular endothelial growth factor	106
Prolyl hydroxylase	103
HIF-1alpha	94
HIF-1	84
proline hydroxylase	84
polypeptide	79
endoplasmic reticulum	69
PHD3	67
lysyl hydroxylase	58
PHD1	56
PHD	54
proteasome	48
lysyl oxidase	42
collagenase	40
protein disulfide isomerase	37
hemoglobin	35
ubiquitin	34
VEGF	30
type I collagen	30
cytokine	28
pVHL	27
fibronectin	24
ATP	23
E3 ubiquitin ligase	23
ubiquitin ligase	22
HIF-1 alpha	22
p53	22
insulin	21
von Hippel-Lindau tumor suppressor	21
VHL	20
type I procollagen	20
glucose transporter	19
disulfide isomerase	19
alkaline phosphatase	19
microsomal	19
HIF1	19
SDS	17
histone	17
vimentin	17
mTOR	17
IL-6	17
p300	16
Skp1	16
Dictyostelium	15
alpha-smooth muscle actin	15
matrix metalloproteinase	15
caspase-3	14
elastin	14
ferritin	14
CD31	13
EGLN3	13
superoxide dismutase	13
erythroid	13
thyroid hormone	13
proline-rich	12
glycosyltransferase	12
microsomal triglyceride transfer protein	12
MMP-2	11
CD34	11
MMP-9	11
ACS	11
inducible nitric oxide synthase	11
Lysyl hydroxylase	11
Erythropoietin	11
type II collagen	11
proteoglycan	10
transcriptional factor	10
glutathione-insulin transhydrogenase	10
SCF	10
PDI	10
CaSR	10
heme oxygenase-1	10
peroxidase	10
membrane-bound	10

Disease
cancer	171
tumor	133
Hippel	120
anemia	109
ischemia	64
cirrhosis	46
tumor growth	37
stroke	34
tumorigenesis	32
liver fibrosis	30
tumor progression	30
hepatocellular carcinoma	30
breast cancer	28
pulmonary fibrosis	27
erythrocytosis	24
carcinoma	18
myocardial infarction	18
SDS	17
hypertension	16
diabetes	16
liver disease	16
pulmonary hypertension	14
atherosclerosis	14
hepatitis	12
polycythemia	12
melanoma	12
colitis	11
Alzheimer's disease	11
obesity	10
cold	10
tumor angiogenesis	10
lung cancer	10
iron deficiency	10
cardiovascular disease	10
renal cell carcinoma	10
rheumatoid arthritis	10
Parkinson's disease	10
myocardial ischemia	10
FIH	10
pheochromocytoma	9
glioma	9
carcinogenesis	9
cerebral ischemia	9
inflammatory bowel disease	9
metastases	9
retinopathy	8
chronic liver disease	8
depression	8
prostate cancer	8
hyperglycemia	8
osteosarcoma	8
paraganglioma	8
colorectal cancer	7
osteoarthritis	7
colon cancer	7
liver cancer	7
chronic active hepatitis	7
lung disease	7
pancreatic fibrosis	7
renal disease	7
pneumonia	7
liver cancer	6
scleroderma	6
bronchopulmonary dysplasia	6
acute hepatitis	6
diabetic nephropathy	6
worms	6
fatty liver	6
adenocarcinoma	5
gastric cancer	5
ulcerative colitis	5
proteinuria	5
MCF	5
Pancreas	5
Pancreas	5
lymphoma	5
iron overload	5
retinopathy of prematurity	5
chronic obstructive pulmonary disease	5
Ehlers-Danlos syndrome	5

Enzyme
prolyl hydroxylase	1814
lysyl hydroxylase	62
PHD	54
proteasome	49
collagenase	49
galactosylhydroxylysyl glucosyltransferase	42
lysyl oxidase	40
ERK	25
type III procollagen	21
luciferase	19
alkaline phosphatase	19
mitogen-activated protein kinase	19
superoxide dismutase	17
peroxidase	16
succinate dehydrogenase	16
pepsin	14
lactate dehydrogenase	13
trypsin	13
protein disulfide-isomerase	13
caspase-3	12
prolyl 3-hydroxylase	11
ACS	11
PDK1	10
protein kinase	10
alanine aminotransferase	10
gamma-glutamyl transpeptidase	10
phosphatidylinositol 3-kinase	9
protein kinase C	8
AMP-activated protein kinase	8
fumarase	7
hexokinase	7
NO synthase	7
focal adhesion kinase	6
aspartate aminotransferase	6
creatine kinase	6
carbonic anhydrase	6
thymidine kinase	6
heme oxygenase	5
catalase	5
complex I	5
NADPH oxidase	5
acid phosphatase	5
NADPH oxidase	5
tyrosine hydroxylase	5
proline oxidase	4
glutathione S-transferase	4
ribonucleotide reductase	4
cytochrome oxidase	4
elastase	4
isocitrate dehydrogenase	4
isocitrate dehydrogenase	4
chymotrypsin	4
collagen galactosyltransferase	4
enolase	4
cdc2	4
beta-glucuronidase	4
phospholipase C	4
alpha-ketoglutarate dehydrogenase	3
aldehyde dehydrogenase	3
phosphoserine phosphatase	3
RNA polymerase	3
ribonucleotide reductase	3
MMP	3
MMP-3	3
pyruvate dehydrogenase	3
matrix metalloproteinase 2	3
tyrosinase	3
citrate synthase	3
cathepsin D	3
ascorbate oxidase	3
aldehyde dehydrogenase	3
aldehyde dehydrogenase	3
phosphofructokinase	3
transglutaminase	3
pyruvate dehydrogenase	3
RNase	3
ornithine aminotransferase	3
pyruvate kinase	3
aldehyde dehydrogenase	3
pyruvate dehydrogenase	3