Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.14.11.2 (prolyl hydroxylase)
 1,814 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
collagen 562
prolyl 4-hydroxylase 447
PHD2 150
Mol 128
Sep 112
erythropoietin 109
vascular endothelial growth factor 106
Prolyl hydroxylase 103
HIF-1alpha 94
HIF-1 84
proline hydroxylase 84
polypeptide 79
endoplasmic reticulum 69
PHD3 67
lysyl hydroxylase 58
PHD1 56
PHD 54
proteasome 48
lysyl oxidase 42
collagenase 40
more...
Disease
cancer 171
tumor 133
Hippel 120
anemia 109
ischemia 64
cirrhosis 46
tumor growth 37
stroke 34
tumorigenesis 32
hepatocellular carcinoma 30
liver fibrosis 30
tumor progression 30
breast cancer 28
pulmonary fibrosis 27
erythrocytosis 24
myocardial infarction 18
carcinoma 18
SDS 17
diabetes 16
hypertension 16
more...
Symptom
starvation 10
hyperoxia 8
respiratory distress 6
pain 5
functional recovery 3
dyspnea 2
hypothermia 2
hypotonia 2
diarrhea 2
dysesthesia 2
cachexia 2
thinning 2
Cold intolerance 1
polydipsia 1
numbness 1
anesthesia 1
nausea 1
splenomegaly 1
abdominal pain 1
hypercapnia 1
more...
Drug
ascorbate 94
lysine 41
Dermatol 18
CoCl2 13
CoCl2 13
Cardiovasc 10
Asn 8
Dial 7
NADH 6
Gel 6
ROS 5
CSF 5
Malotilate 3
Angiotensin II 3
Nitric Oxide 2
Heme 2
Rosiglitazone 2
DNase I 2
Triclosan 2
Oxaliplatin 2
more...
Enzyme
prolyl hydroxylase 1814
lysyl hydroxylase 62
PHD 54
collagenase 49
proteasome 49
galactosylhydroxylysyl glucosyltransferase 42
lysyl oxidase 40
ERK 25
type III procollagen 21
luciferase 19
alkaline phosphatase 19
mitogen-activated protein kinase 19
superoxide dismutase 17
peroxidase 16
succinate dehydrogenase 16
pepsin 14
protein disulfide-isomerase 13
trypsin 13
lactate dehydrogenase 13
caspase-3 12
more...
Compound
oxygen 446
proline 260
2-oxoglutarate 178
iron 167
Dec 132
DNA 107
Collagen 69
glucose 66
Clin 64
Hydroxyproline 57
lysine 52
4-hydroxyproline 44
4-hydroxyproline 44
4-hydroxyproline 44
4-hydroxyproline 44
4-hydroxyproline 44
4-hydroxyproline 44
Pro-Gly 34
pyridine 26
Ascorbic acid 26
more...