Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.13.12.7 (firefly luciferase)
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Human Gene/Protein
NF-kappaB activating protein 13.5
YTH domain containing 2 12.5
Mucosal vascular addressin cell adhesion molecule 1 11.9
Disco-interacting protein 2 homolog B 11.9
SCFV 11.9
WDR65 11.5
Na,K-ATPase beta 1 subunit 11.2
Hox-2.5 10.7
vitamin D receptor interacting protein 10.7
protein-L-isoaspartate (D-aspartate) O-methyltransferase 10.7
U11/U12-31K 10.5
heat shock-induced protein 10.3
Epilysin 10.3
PLAP-1 10.3
PMP34 10.2
L-myc protein 10.0
GPR27 9.9
rab18 9.8
DnaJ homolog 9.7
rpl3 9.7
LEF1 protein 9.7
hCTR2 9.7
acyl-CoA synthetase long-chain family member 1 9.7
PGAM-M 9.7
CAT5 9.6
GRIP2 9.6
ADAMTS16 9.5
HUG1 9.5
Interleukin 16 9.5
DLK2 9.5
JM4 9.4
KIAA1549:BRAF 9.4
PILRA 9.4
AOC1 9.4
epilysin 9.3
ZHX1 9.2
LI2 9.2
E4TF1 9.2
molybdenum cofactor sulfurase 9.1
TLR3 protein 9.1
GPR173 9.1
TIM10 9.0
Amine oxidase 9.0
NeuroD6 9.0
transcription factor AP2 8.9
SREB2 8.8
brother of the regulator of imprinted sites 8.8
UTR2 8.8
rapamycin-binding protein 8.8
SYVN1 8.8
complement component C7 8.8
OSF2 8.7
UGT2A1 8.7
HSDJ 8.6
eIF3f 8.5
LST1 8.5
ATP binding protein 8.5
DiGeorge syndrome critical region gene 8 8.5
CAB2 8.5
DnaJ 8.4
APP1 8.4
nucleoporin 98 8.4
PSMA7 8.4
ALD1 8.3
Cystatin B 8.3
NIM1 8.3
HOS1 8.3
RPS10 8.3
PVRL4 8.2
M83 8.2
NGFI-C 8.2
period1 8.2
NOVA1 8.2
Hsp40 8.1
RPL10 8.1
MZF-1 8.1
myeloid zinc finger 8.1
ATP-hydrolysing 8.1
GDN 8.1
Fibulin-2 8.0
more...
Disease
LI2 9.6
DFNA15 9.3
PGL3 9.2
Corneal infection 8.6
Behr 8.3
Morphine dependence 8.0
Rhizomelic chondrodysplasia punctata 7.9
Clonal evolution 7.0
in situ breast cancer 6.8
PLAT 6.5
LBD 6.2
EDS1 6.1
Alexander disease 6.0
Rous sarcoma 6.0
monkeypox 5.9
nagana 5.8
TNS 5.7
CPL 5.7
Renovascular hypertension 5.7
Malignant peripheral nerve sheath tumor 5.7
HTS 5.6
genital herpes simplex 5.6
genital herpes simplex 5.6
Retinal degeneration 5.6
gliosarcoma 5.6
western equine encephalomyelitis 5.5
Hand, foot, and mouth disease 5.4
ACS1 5.3
NCR 5.3
ornithine transcarbamylase deficiency 5.3
brain cancer 5.2
recurrent prostate cancer 5.1
MPS VII 5.1
metastatic ovarian cancer 5.0
ACV 5.0
PCS 5.0
anaplastic thyroid cancer 4.8
MODY 4.8
Vesicular stomatitis 4.8
platelet disorder 4.7
MAR 4.7
Malignant peripheral nerve sheath tumor 4.6
herpes simplex 4.6
vaccinia 4.6
Tick-borne encephalitis 4.6
HRS 4.6
embryonal carcinoma 4.6
NS3 4.5
Aujeszky's disease 4.5
Testes 4.5
HSP 4.5
cytomegalovirus 4.5
PCD 4.5
SCID 4.4
CCD 4.4
Classical swine fever 4.4
pituitary tumor 4.4
Tropical Diseases 4.4
NOD 4.4
CCD 4.4
teratoma 4.3
bacteriuria 4.3
Johne's disease 4.3
laryngotracheitis 4.3
CCL 4.2
gastrointestinal infection 4.1
Stomach 4.1
Stomach 4.1
Stomach 4.1
smallpox 4.1
primary hyperoxaluria 4.1
Foot-and-mouth disease 4.1
hepatoblastoma 4.1
WSN 4.1
WSN 4.0
localized infection 4.0
Stomach 4.0
tumor growth 4.0
delirium tremens 4.0
Glioblastoma 4.0
more...
Symptom
No toxic effect 7.1
pachyonychia 6.0
POA 4.4
HSA 1.9
starvation 1.9
functional recovery 1.3
hyperoxia 1.1
lethargy 1.0
tremor 0.9
anesthesia 0.5
respiratory distress 0.2
agitation -0.1
stigma -0.2
exhaustion -0.3
anorexia -0.3
ataxia -0.5
hypothermia -0.6
weakness -0.7
overweight -1.2
seizures -1.2
diarrhea -2.3
pain -3.5
Drug
Tnt 10.9
Glafenine 9.9
Triptorelin 7.2
hCRH 7.2
Cetrorelix 6.9
Intron A 6.6
Intron A 6.4
Intron A 6.4
Ibandronate 6.2
Tranilast 5.8
Palivizumab 5.8
PE2 5.7
Ranolazine 5.5
Ranolazine 5.5
CER 5.4
G418 5.4
anti-CD33 5.1
AC2 5.1
K-252a 5.1
Doxycycline 5.0
AGG 4.9
Doyle 4.8
RFP 4.8
Dihydrotestosterone 4.8
Adenosine triphosphate 4.7
Hyaluronidase 4.7
Rosuvastatin 4.7
anti-RSV 4.6
Hyaluronidase 4.5
Singular 4.5
Troglitazone 4.4
Oseltamivir 4.2
Triad 4.2
VCR 4.2
R1881 4.2
CCL 4.1
Raloxifene 4.0
Bortezomib 3.9
DMSA 3.9
Ganciclovir 3.9
MgSO4 3.9
Ranitidine 3.8
TAT 3.8
DNase I 3.8
BoNT/A 3.7
Gel 3.7
TTC 3.6
Cetuximab 3.6
Spectrum 3.5
AraC 3.4
DPA 3.2
Arsenic trioxide 3.2
IFN-beta 2.9
Sorafenib 2.9
Allergen 2.9
VCR 2.9
Taxol 2.8
PTC 2.7
ICI 2.7
Spectrum 2.5
Itraconazole 2.5
-deoxyadenosine 2.5
ACT 2.4
DHT 2.4
DHT 2.3
Fragment 2.3
CDP 2.3
L-tyrosine 2.3
Silica 2.3
Nitric Oxide 2.1
Forskolin 2.1
Alanine 2.0
lysine 2.0
Asn 2.0
Heme 1.9
IFN-gamma 1.8
Ethanol 1.8
Retinoic acid 1.7
MRC 1.7
Glucagon 1.6
more...
Enzyme
firefly luciferase 13.5
Cypridina luciferase 10.9
Oplophorus luciferase 9.8
luciferase 8.6
phenylacetyl-CoA ligase 8.5
ATP sulfurylase 8.5
EC 3.6.1.17 8.4
acetylornithine aminotransferase 8.2
ACV synthetase 8.1
Ap4A hydrolase 7.9
pyrrolysyl-tRNA synthetase 7.8
isopenicillin N synthetase 7.7
organomercurial lyase 7.3
acyl-CoA synthetase 7.1
histidinol dehydrogenase 7.0
acetyl-CoA synthetase 7.0
FtsH protease 6.9
phosphatidylinositol phospholipase C 6.9
acyl-CoA synthetase 6.9
dynamin GTPase 6.8
thymidine kinase 6.7
2A protease 6.6
adenylate kinase 6.6
xyloglucan endotransglycosylase 6.6
EC 3.6.1.1 6.4
isochorismate synthase 6.3
chloramphenicol acetyltransferase 6.3
calpain 3 6.2
hydroxypyruvate reductase 6.0
hydroxypyruvate reductase 5.9
GLO 5.8
HC-Pro 5.8
aequorin 5.8
Mg-chelatase 5.8
uridyltransferase 5.7
beta-galactosidase 5.7
exonuclease I 5.7
polyphosphate kinase 5.7
acetate kinase 5.6
fatty acid elongase 5.5
apyrase 5.5
CPL 5.5
acyl-CoA thioesterase 5.4
thymidylate kinase 5.3
fumarylacetoacetate hydrolase 5.3
UDP-glucose dehydrogenase 5.2
GAS 5.2
4CL 5.1
granule-bound starch synthase 5.1
acetoacetyl-CoA thiolase 5.1
RNA ligase 5.1
fatty acid desaturase 5.0
guanylate kinase 5.0
rhodanese 4.9
cytosine deaminase 4.9
peptidyl-prolyl cis-trans isomerase 4.9
S1 nuclease 4.8
calpain 3 4.7
chaperonin 4.7
venom phosphodiesterase 4.6
glyceraldehyde-3-phosphate dehydrogenase 4.6
pyruvate kinase 4.6
beta-glucuronidase 4.6
lysostaphin 4.6
glyceraldehyde-3-phosphate dehydrogenase 4.6
glyceraldehyde-3-phosphate dehydrogenase 4.5
3C protease 4.5
lysyl endopeptidase 4.5
dihydroorotate dehydrogenase 4.5
dihydroorotate dehydrogenase 4.5
pyruvate carboxylase 4.5
CYP27A1 4.4
phosphoglycerate kinase 4.4
p80 4.4
estrogen sulfotransferase 4.3
glyceraldehyde-3-phosphate dehydrogenase 4.3
thromboxane synthase 4.3
cytochrome P-450scc 4.3
PI-PLC 4.3
prostate-specific antigen 4.3
more...
Compound
Photinus luciferin 12.9
2,4-dichlorobenzamide 11.9
Bisphenol B 10.2
Sinomenine hydrochloride 10.2
Androstenol 10.0
CDP-glucose 9.6
2,5-dihydro-1H-pyrrole 9.4
1,4-phthalazinedione 8.8
Diadenosine tetraphosphate 8.7
Resorufin 8.3
Blasticidin S 8.3
NAAG 7.6
PTSM 7.6
1-tetradecanol 7.5
1-nonanol 7.4
1-octadecanol 7.4
TMG 7.2
Cypridina luciferin 7.1
Withaferin A 7.0
dCDP 6.9
1-decanol 6.8
TCTP 6.8
4-octylphenol 6.7
3,5-dichlorophenol 6.6
Resazurin 6.6
PPi 6.6
4-chlorobenzoic acid 6.5
1-undecanol 6.5
dADP 6.5
Toxaphene 6.5
1,3-cyclohexanedione 6.4
Saxitoxin 6.3
C 10 6.3
LY 294002 6.3
C 10 6.3
NaAsO2 6.2
C 6 6.2
Zanamivir 6.2
adenylate 6.2
2-phosphoglycerate 6.2
1-heptanol 6.2
TTNPB 6.2
ELA 6.1
PIH 6.1
ELA 6.1
Glyceraldehyde 6.1
Latrunculin A 6.1
1,3-butanediol 6.1
TETA 6.1
Dihydroxyacetone 6.0
1,3-butanediol 6.0
tetraphosphate 5.9
Nelfinavir 5.9
decanal 5.9
pentanedioic acid 5.9
DOPE 5.9
decanal 5.9
Benzalkonium chloride 5.9
Anisomycin 5.9
P2A 5.8
CDP-ethanolamine 5.8
2,4-pentanedione 5.8
Mithramycin 5.8
CPL 5.7
TCDD 5.7
1-dodecanol 5.6
Jasmonic acid 5.6
dATP 5.6
1,3-propanediamine 5.5
Tetrandrine 5.5
Tetrandrine 5.5
Tetrandrine 5.5
Tetrandrine 5.5
Cyproterone acetate 5.5
ASN 5.4
DLG 5.4
Chalcone 5.3
Cystathionine 5.3
MPB 5.3
Cystathionine 5.3
more...