Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.13.12.7 (firefly luciferase)
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Human Gene/Protein
NF-kappaB activating protein 13.5
YTH domain containing 2 12.5
Disco-interacting protein 2 homolog B 11.9
Mucosal vascular addressin cell adhesion molecule 1 11.9
SCFV 11.9
WDR65 11.5
Na,K-ATPase beta 1 subunit 11.2
vitamin D receptor interacting protein 10.7
Hox-2.5 10.7
protein-L-isoaspartate (D-aspartate) O-methyltransferase 10.7
U11/U12-31K 10.5
Epilysin 10.3
heat shock-induced protein 10.3
PLAP-1 10.3
PMP34 10.2
L-myc protein 10.0
GPR27 9.9
rab18 9.8
DnaJ homolog 9.7
acyl-CoA synthetase long-chain family member 1 9.7
LEF1 protein 9.7
hCTR2 9.7
rpl3 9.7
PGAM-M 9.7
GRIP2 9.6
CAT5 9.6
DLK2 9.5
Interleukin 16 9.5
HUG1 9.5
ADAMTS16 9.5
PILRA 9.4
JM4 9.4
AOC1 9.4
KIAA1549:BRAF 9.4
epilysin 9.3
ZHX1 9.2
E4TF1 9.2
LI2 9.2
GPR173 9.1
TLR3 protein 9.1
molybdenum cofactor sulfurase 9.1
TIM10 9.0
NeuroD6 9.0
Amine oxidase 9.0
transcription factor AP2 8.9
SREB2 8.8
brother of the regulator of imprinted sites 8.8
SYVN1 8.8
UTR2 8.8
rapamycin-binding protein 8.8
complement component C7 8.8
OSF2 8.7
UGT2A1 8.7
HSDJ 8.6
CAB2 8.5
ATP binding protein 8.5
eIF3f 8.5
DiGeorge syndrome critical region gene 8 8.5
LST1 8.5
DnaJ 8.4
PSMA7 8.4
nucleoporin 98 8.4
APP1 8.4
ALD1 8.3
Cystatin B 8.3
NIM1 8.3
HOS1 8.3
RPS10 8.3
PVRL4 8.2
M83 8.2
NGFI-C 8.2
period1 8.2
NOVA1 8.2
Hsp40 8.1
RPL10 8.1
MZF-1 8.1
myeloid zinc finger 8.1
ATP-hydrolysing 8.1
GDN 8.1
Fibulin-2 8.0
UPII 8.0
CSBP 8.0
IP6K 8.0
NFBD1 8.0
DLG4 8.0
KLF7 7.9
ACADVL 7.9
ribosomal protein L2 7.9
HspBP1 7.9
FOXL1 7.9
hedgehog interacting protein 7.9
PEX13 7.9
alcohol dehydrogenase 1 7.9
MMP-28 7.9
HSF1 protein 7.9
sodium-dependent multivitamin transporter 7.8
hSVCT1 7.8
IFNLR1 7.8
UEV1A 7.8
DnaJ protein 7.7
PLCzeta 7.7
long chain acyl-CoA dehydrogenase 7.7
ARRB2 7.7
ICS1 7.6
NF-E1 7.6
MTF1 7.6
A6L 7.6
FK506-binding protein 12 7.6
class I cytokine receptor 7.6
HBE1 7.6
MT-1A 7.6
Pax-4 7.6
Acyl-CoA synthetase 7.6
OAZ1 7.5
HveC 7.5
thyroid hormone receptor alpha 7.5
KRC 7.5
p82 7.5
growth factor receptor binding protein 7.5
sarcospan 7.5
sperm receptor 7.4
OTF-1 7.4
ribosomal protein S7 7.4
all-trans and 9-cis 7.4
PRR5 7.4
CDH5 7.4
AGGG 7.4
Growth hormone receptor 7.4
S52 7.4
G6PC3 7.4
OG2 7.3
Pol protein 7.3
p10 protein 7.3
D29 7.3
DnaJ-like 7.3
POU4F3 7.3
TPM4 7.3
BHLHE40 7.3
isoprenylcysteine carboxyl methyltransferase 7.2
RAPA 7.2
acyl-CoA synthetase 7.2
RPS2 7.2
SRp55 7.2
ferritin heavy chain 7.2
APS kinase 7.1
alpha-MHC 7.1
PPK 7.1
GPR17 7.1
TUBA1A 7.1
EEF1A1 7.1
Sp1 protein 7.1
LH2 7.1
embryonic ectoderm development 7.1
HB1 7.1
FRB 7.1
ribosomal protein L4 7.1
HHIP 7.1
PEX7 7.1
CACC 7.1
acetyl-CoA synthetase 7.1
more...
Disease
LI2 9.6
DFNA15 9.3
PGL3 9.2
Corneal infection 8.6
Behr 8.3
Morphine dependence 8.0
Rhizomelic chondrodysplasia punctata 7.9
Clonal evolution 7.0
in situ breast cancer 6.8
PLAT 6.5
LBD 6.2
EDS1 6.1
Alexander disease 6.0
Rous sarcoma 6.0
monkeypox 5.9
nagana 5.8
TNS 5.7
CPL 5.7
Renovascular hypertension 5.7
Malignant peripheral nerve sheath tumor 5.7
HTS 5.6
genital herpes simplex 5.6
genital herpes simplex 5.6
Retinal degeneration 5.6
gliosarcoma 5.6
western equine encephalomyelitis 5.5
Hand, foot, and mouth disease 5.4
ACS1 5.3
NCR 5.3
ornithine transcarbamylase deficiency 5.3
brain cancer 5.2
recurrent prostate cancer 5.1
MPS VII 5.1
metastatic ovarian cancer 5.0
ACV 5.0
PCS 5.0
anaplastic thyroid cancer 4.8
MODY 4.8
Vesicular stomatitis 4.8
platelet disorder 4.7
MAR 4.7
Malignant peripheral nerve sheath tumor 4.6
herpes simplex 4.6
vaccinia 4.6
Tick-borne encephalitis 4.6
HRS 4.6
embryonal carcinoma 4.6
NS3 4.5
Aujeszky's disease 4.5
Testes 4.5
HSP 4.5
cytomegalovirus 4.5
PCD 4.5
SCID 4.4
CCD 4.4
Classical swine fever 4.4
pituitary tumor 4.4
Tropical Diseases 4.4
NOD 4.4
CCD 4.4
teratoma 4.3
bacteriuria 4.3
Johne's disease 4.3
laryngotracheitis 4.3
CCL 4.2
gastrointestinal infection 4.1
Stomach 4.1
Stomach 4.1
Stomach 4.1
smallpox 4.1
primary hyperoxaluria 4.1
Foot-and-mouth disease 4.1
hepatoblastoma 4.1
WSN 4.1
WSN 4.0
localized infection 4.0
Stomach 4.0
tumor growth 4.0
delirium tremens 4.0
Glioblastoma 4.0
MCS 4.0
Human immunodeficiency virus type 4.0
MCS 3.9
ADCC 3.9
COL2A1 3.9
molluscum contagiosum 3.9
RTS 3.9
Adenovirus 3.9
recurrent cancer 3.9
prostatic disease 3.8
galactosemia 3.8
choriocarcinoma 3.8
trypanosomiasis 3.8
diphtheria 3.8
cervical dysplasia 3.8
mammary tumor 3.8
ileitis 3.8
Lip 3.7
NS2 3.7
malignant pleural effusion 3.7
malignant ascites 3.7
hepatitis C 3.7
RGS 3.7
skin tumor 3.6
Tumour necrosis 3.6
stomatitis 3.5
CDA 3.5
ehrlichiosis 3.5
Schistosoma mansoni 3.5
avian leukosis 3.5
toxic shock syndrome 3.4
PGA 3.4
MCF 3.4
Marek's disease 3.4
Spinal muscular atrophy 3.4
glioblastoma 3.4
Venezuelan equine encephalitis 3.4
Osteosarcoma 3.4
Osteosarcoma 3.4
hepatitis A 3.4
glioma 3.4
Ovary 3.4
HOS 3.3
Condensation 3.3
PER 3.3
glioblastoma multiforme 3.3
PPP 3.3
EL4 3.3
fascioliasis 3.3
bovine leukemia 3.2
brain tumor 3.2
fibrosarcoma 3.2
Sweet 3.2
Krabbe disease 3.2
septal defect 3.2
Thyroid cancer 3.1
PCL 3.1
neuromuscular disorder 3.1
lung metastases 3.1
achondroplasia 3.0
CEM 3.0
herpes 3.0
HSV infection 3.0
acute nonlymphocytic leukemia 3.0
LDA 3.0
parvovirus 3.0
hepatocellular carcinoma 2.9
Gaucher disease 2.9
AAA 2.9
primary tumor 2.9
tumor progression 2.9
bone metastases 2.8
plant disease 2.8
B-ALL 2.8
LAD 2.8
Tag 2.8
epithelial ovarian cancer 2.8
endometrial adenocarcinoma 2.8
mastocytoma 2.7
intracranial tumors 2.7
more...
Symptom
No toxic effect 7.1
pachyonychia 6.0
POA 4.4
HSA 1.9
starvation 1.9
functional recovery 1.3
hyperoxia 1.1
lethargy 1.0
tremor 0.9
anesthesia 0.5
respiratory distress 0.2
agitation -0.1
stigma -0.2
exhaustion -0.3
anorexia -0.3
ataxia -0.5
hypothermia -0.6
weakness -0.7
overweight -1.2
seizures -1.2
diarrhea -2.3
pain -3.5
Drug
Tnt 10.9
Glafenine 9.9
Triptorelin 7.2
hCRH 7.2
Cetrorelix 6.9
Intron A 6.6
Intron A 6.4
Intron A 6.4
Ibandronate 6.2
Tranilast 5.8
Palivizumab 5.8
PE2 5.7
Ranolazine 5.5
Ranolazine 5.5
CER 5.4
G418 5.4
anti-CD33 5.1
AC2 5.1
K-252a 5.1
Doxycycline 5.0
AGG 4.9
Doyle 4.8
RFP 4.8
Dihydrotestosterone 4.8
Adenosine triphosphate 4.7
Rosuvastatin 4.7
Hyaluronidase 4.7
anti-RSV 4.6
Hyaluronidase 4.5
Singular 4.5
Troglitazone 4.4
Oseltamivir 4.2
Triad 4.2
VCR 4.2
R1881 4.2
CCL 4.1
Raloxifene 4.0
DMSA 3.9
Bortezomib 3.9
Ganciclovir 3.9
MgSO4 3.9
Ranitidine 3.8
TAT 3.8
DNase I 3.8
BoNT/A 3.7
Gel 3.7
TTC 3.6
Cetuximab 3.6
Spectrum 3.5
AraC 3.4
DPA 3.2
Arsenic trioxide 3.2
IFN-beta 2.9
Sorafenib 2.9
Allergen 2.9
VCR 2.9
Taxol 2.8
PTC 2.7
ICI 2.7
Spectrum 2.5
Itraconazole 2.5
-deoxyadenosine 2.5
ACT 2.4
DHT 2.4
DHT 2.3
Fragment 2.3
CDP 2.3
L-tyrosine 2.3
Silica 2.3
Nitric Oxide 2.1
Forskolin 2.1
Alanine 2.0
lysine 2.0
Asn 2.0
Heme 1.9
IFN-gamma 1.8
Ethanol 1.8
Retinoic acid 1.7
MRC 1.7
Glucagon 1.6
EE2 1.5
PCB 1.4
Albumin 1.2
Glutathione 1.1
Histamine 1.0
IL-2 1.0
Nephron 0.9
Mutagen 0.9
ROS 0.8
EPA 0.7
Leaf 0.7
ascorbate 0.6
MAP 0.5
ABC 0.4
nitroglycerin 0.4
CSF 0.1
caffeine 0.1
NADH 0.1
ZnO -0.3
lactose -0.5
ampicillin -0.6
vitamin E -0.6
Cardiovasc -1.8
Dermatol -4.5
Enzyme
firefly luciferase 13.5
Cypridina luciferase 10.9
Oplophorus luciferase 9.8
luciferase 8.6
phenylacetyl-CoA ligase 8.5
ATP sulfurylase 8.5
EC 3.6.1.17 8.4
acetylornithine aminotransferase 8.2
ACV synthetase 8.1
Ap4A hydrolase 7.9
pyrrolysyl-tRNA synthetase 7.8
isopenicillin N synthetase 7.7
organomercurial lyase 7.3
acyl-CoA synthetase 7.1
histidinol dehydrogenase 7.0
acetyl-CoA synthetase 7.0
FtsH protease 6.9
phosphatidylinositol phospholipase C 6.9
acyl-CoA synthetase 6.9
dynamin GTPase 6.8
thymidine kinase 6.7
2A protease 6.6
adenylate kinase 6.6
xyloglucan endotransglycosylase 6.6
EC 3.6.1.1 6.4
isochorismate synthase 6.3
chloramphenicol acetyltransferase 6.3
calpain 3 6.2
hydroxypyruvate reductase 6.0
hydroxypyruvate reductase 5.9
GLO 5.8
HC-Pro 5.8
aequorin 5.8
Mg-chelatase 5.8
uridyltransferase 5.7
beta-galactosidase 5.7
exonuclease I 5.7
polyphosphate kinase 5.7
acetate kinase 5.6
fatty acid elongase 5.5
apyrase 5.5
CPL 5.5
acyl-CoA thioesterase 5.4
thymidylate kinase 5.3
fumarylacetoacetate hydrolase 5.3
UDP-glucose dehydrogenase 5.2
GAS 5.2
4CL 5.1
granule-bound starch synthase 5.1
acetoacetyl-CoA thiolase 5.1
RNA ligase 5.1
fatty acid desaturase 5.0
guanylate kinase 5.0
rhodanese 4.9
cytosine deaminase 4.9
peptidyl-prolyl cis-trans isomerase 4.9
S1 nuclease 4.8
calpain 3 4.7
chaperonin 4.7
venom phosphodiesterase 4.6
glyceraldehyde-3-phosphate dehydrogenase 4.6
pyruvate kinase 4.6
beta-glucuronidase 4.6
lysostaphin 4.6
glyceraldehyde-3-phosphate dehydrogenase 4.6
glyceraldehyde-3-phosphate dehydrogenase 4.5
3C protease 4.5
lysyl endopeptidase 4.5
dihydroorotate dehydrogenase 4.5
dihydroorotate dehydrogenase 4.5
pyruvate carboxylase 4.5
CYP27A1 4.4
phosphoglycerate kinase 4.4
p80 4.4
estrogen sulfotransferase 4.3
glyceraldehyde-3-phosphate dehydrogenase 4.3
cytochrome P-450scc 4.3
thromboxane synthase 4.3
PI-PLC 4.3
prostate-specific antigen 4.3
dihydrofolate reductase 4.3
hexokinase 4.3
MTD 4.3
prolyl hydroxylase 4.2
galactokinase 4.2
transcriptase 4.2
factor C 4.2
porphobilinogen deaminase 4.2
granzyme B 4.1
polynucleotide kinase 4.1
RNase P 4.1
glutathione synthetase 4.1
PGM 4.0
glyceraldehyde-3-phosphate dehydrogenase 4.0
transpeptidase 4.0
glycerol kinase 4.0
aldehyde oxidase 4.0
citrate synthase 3.9
malate dehydrogenase 3.9
MCS 3.9
acyl-CoA dehydrogenase 3.9
TAT 3.8
RNA polymerase 3.8
PHD 3.7
prostate-specific membrane antigen 3.7
caspase-7 3.7
ALDH 3.7
p100 3.7
DNA ligase 3.6
DNA ligase 3.6
caspase-7 3.6
adenosine kinase 3.6
cGMP phosphodiesterase 3.6
acyl-CoA oxidase 3.5
formate dehydrogenase 3.5
CYP7A1 3.5
formate dehydrogenase 3.5
isocitrate lyase 3.5
deaminase 3.5
glucose dehydrogenase 3.5
angiotensin-converting enzyme 2 3.5
nucleotidase 3.5
lysin 3.5
ricin 3.4
formate dehydrogenase 3.4
GRK5 3.3
myosin ATPase 3.3
TSA 3.2
Thy1 3.2
RNase T1 3.2
xanthine dehydrogenase 3.2
enolase 3.2
tissue kallikrein 3.2
CPS 3.2
tyrosinase 3.1
transketolase 3.1
glucose-6-phosphate dehydrogenase 3.1
sialidase 3.1
phosphoglucomutase 3.1
proteasome 3.1
RNase H 3.1
phosphoenolpyruvate carboxykinase 3.0
phosphoenolpyruvate carboxykinase 3.0
purine nucleoside phosphorylase 3.0
acyl-CoA dehydrogenase 3.0
gamma-glutamylcysteine synthetase 3.0
glucocerebrosidase 3.0
histidine decarboxylase 3.0
TOR 3.0
Mg2+-ATPase 2.9
triphosphatase 2.9
DNase 2.9
polo-like kinase 1 2.9
phosphoenolpyruvate carboxykinase 2.9
chymotrypsin 2.9
ornithine decarboxylase 2.8
CYP3A4 2.8
leucine aminopeptidase 2.8
IKK 2.8
ATPase 2.8
more...
Compound
Photinus luciferin 12.9
2,4-dichlorobenzamide 11.9
Bisphenol B 10.2
Sinomenine hydrochloride 10.2
Androstenol 10.0
CDP-glucose 9.6
2,5-dihydro-1H-pyrrole 9.4
1,4-phthalazinedione 8.8
Diadenosine tetraphosphate 8.7
Resorufin 8.3
Blasticidin S 8.3
NAAG 7.6
PTSM 7.6
1-tetradecanol 7.5
1-nonanol 7.4
1-octadecanol 7.4
TMG 7.2
Cypridina luciferin 7.1
Withaferin A 7.0
dCDP 6.9
1-decanol 6.8
TCTP 6.8
4-octylphenol 6.7
3,5-dichlorophenol 6.6
Resazurin 6.6
PPi 6.6
4-chlorobenzoic acid 6.5
1-undecanol 6.5
dADP 6.5
Toxaphene 6.5
1,3-cyclohexanedione 6.4
Saxitoxin 6.3
C 10 6.3
LY 294002 6.3
C 10 6.3
NaAsO2 6.2
Zanamivir 6.2
C 6 6.2
adenylate 6.2
2-phosphoglycerate 6.2
1-heptanol 6.2
TTNPB 6.2
ELA 6.1
ELA 6.1
PIH 6.1
Glyceraldehyde 6.1
Latrunculin A 6.1
1,3-butanediol 6.1
TETA 6.1
Dihydroxyacetone 6.0
1,3-butanediol 6.0
tetraphosphate 5.9
Nelfinavir 5.9
decanal 5.9
pentanedioic acid 5.9
DOPE 5.9
decanal 5.9
Benzalkonium chloride 5.9
Anisomycin 5.9
P2A 5.8
CDP-ethanolamine 5.8
2,4-pentanedione 5.8
Mithramycin 5.8
CPL 5.7
TCDD 5.7
1-dodecanol 5.6
Jasmonic acid 5.6
dATP 5.6
1,3-propanediamine 5.5
Tetrandrine 5.5
Tetrandrine 5.5
Tetrandrine 5.5
Tetrandrine 5.5
Cyproterone acetate 5.5
ASN 5.4
DLG 5.4
Chalcone 5.3
Cystathionine 5.3
MPB 5.3
Cystathionine 5.3
Psoralen 5.2
4-chlorophenol 5.2
glucosamine-6-phosphate 5.2
Leflunomide 5.1
PEI 5.1
PEI 5.1
TMC 5.1
Sodium azide 5.1
Puromycin 5.0
Prussian Blue 5.0
Doxycycline 5.0
ATC 5.0
m-xylene 5.0
Thymine 5.0
N-(4-hydroxyphenyl)retinamide 4.9
PMP 4.9
ATC 4.9
PMP 4.9
CoA 4.9
7-methylguanosine 4.9
Oseltamivir 4.8
bromoform 4.8
GF 109203X 4.8
PMP 4.8
Kanamycin 4.7
Corticotropin 4.7
ATP 4.7
Iodo 4.7
SP-1 4.7
His-Leu 4.6
o-cresol 4.6
dGTP 4.6
40S 4.6
2-chlorophenol 4.6
DRB 4.6
2-chlorophenol 4.6
Adenine 4.5
dCTP 4.5
Antimycin 4.5
NFS 4.5
myristic acid 4.5
BHC 4.4
Anthocyanin 4.4
Coenzyme A 4.4
APS 4.4
DETA 4.4
ANS 4.3
ANS 4.3
DHBA 4.3
AMP 4.3
Factor H 4.3
Protamine 4.3
Mycophenolate mofetil 4.3
alpha-Tocopherol 4.3
DBD 4.2
propionaldehyde 4.2
Deoxyribonucleic acid 4.2
1-hexanol 4.2
IAA 4.2
COS 4.2
Fluo-3 4.2
myristic acid 4.2
m-cresol 4.1
TET 4.1
TET 4.1
MBT 4.1
Halothane 4.1
Raloxifene 4.1
Phorbol 12-myristate 13-acetate 4.1
Dithiothreitol 4.1
IAA 4.0
TMEDA 4.0
BAF 4.0
DAPT 4.0
Tunicamycin 4.0
1,4-butanediol 4.0
1-octanol 4.0
CuS 4.0
Apigenin 3.9
IBA 3.9
more...