Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.13.12.5 (aequorin)
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Human Gene/Protein
Vma5 13.4
cytochrome c oxidase subunit VIII 12.3
prostanoid EP1 receptor 12.1
GPR63 11.8
G5A 10.8
TAS2R46 10.7
RHOD 10.6
PMCA3 10.5
HES2 10.2
TPCN2 10.1
muscarinic acetylcholine receptor M3 10.0
B1 bradykinin receptor 10.0
CaBP2 10.0
GPR74 10.0
caltractin 9.7
mitogen-activated protein kinase 6 9.7
CNGA2 9.6
MAPK6 9.6
MAGE3 9.6
ORP5 9.6
Mid1 9.3
CNGB1 9.2
NPH1 9.1
PMCA4 9.0
HM74 9.0
BFP 8.9
CGRP2 8.9
ATP2A1 8.9
GALR3 8.9
PMCA2 8.8
TPC1 8.8
SV2C 8.8
AGC1 8.7
Mel1c 8.6
Oxysterol-binding protein 8.6
PLC1 8.6
SPCA1 8.6
platelet phospholipase A2 8.6
Sancho 8.5
P220 8.5
synaptotagmin II 8.5
SV2B 8.4
V1a vasopressin receptor 8.4
GPA2 8.4
TnC 8.4
14-3-3 epsilon 8.3
NL2 8.3
cardiac troponin C 8.3
CAT3 8.2
PL2 8.2
BAC1 8.1
21 kDa protein 8.1
PMCA1 8.1
mitochondrial carrier protein 8.0
leukotriene B4 receptor 8.0
smooth muscle myosin light chain 7.9
calcineurin B-like protein 7.9
ERGIC 7.9
troponin C 7.8
ATP2C1 7.8
SERCA1 7.8
Corin 7.8
adenosine A3 receptor 7.7
GalNAc-transferase 7.7
PIGA 7.7
ST3Gal I 7.7
CLM 7.7
Na+/Ca2+ exchanger 7.7
SPCA 7.7
ERp72 7.6
GALR2 7.6
renal) 7.5
GPR1 7.5
NCX2 7.5
NL1 7.4
corin 7.4
HHD 7.3
SV2A 7.3
GALR1 7.3
apyrase 7.2
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Disease
HPC4 10.5
PGL2 10.2
INAD 7.7
Tension 7.0
HBD 6.4
Ovary 6.3
EMD 6.2
AOS 6.2
NPHP1 6.2
Wolfram syndrome 5.8
idiopathic cardiomyopathy 5.6
Ovary 5.6
neuromyotonia 5.5
PAF 5.2
PDP 5.1
Tic 5.0
lactose intolerance 4.9
tetanus 4.9
Glanzmann's thrombasthenia 4.6
Graves' ophthalmopathy 4.4
CAP 4.4
PAL 4.3
idiopathic thrombocytopenic purpura 4.3
PPP 4.2
malignant hyperthermia 4.2
CHS 4.2
neuromuscular disorder 4.1
Ischemic stroke 4.0
INS 3.9
Raynaud 3.8
plant disease 3.8
primary pulmonary hypertension 3.7
EDC 3.7
insulinoma 3.6
MLC 3.4
pertussis 3.3
optic atrophy 3.3
alkalosis 3.3
CCD 3.2
idiopathic dilated cardiomyopathy 3.1
CCD 3.1
HSP 3.1
PDE 3.1
Duchenne muscular dystrophy 3.1
cold 3.0
sympathomimetic 2.9
PSS 2.9
PSS 2.9
Blocking 2.9
dilated cardiomyopathy 2.8
drunk 2.8
tic 2.8
osteosarcoma 2.7
heart failure 2.7
PSS 2.6
ventricular hypertrophy 2.5
Dissociation 2.5
follicular lymphoma 2.5
congestive heart failure 2.4
FAS 2.4
cholera 2.4
photosensitivity 2.4
proptosis 2.4
thrombocytopenic purpura 2.4
ileus 2.3
Prostate Cancer 2.3
minimal residual disease 2.2
infestation 2.1
myeloproliferative disorders 2.1
hyperthyroidism 2.1
neuroblastoma 2.0
CAM 2.0
ischemia 1.9
scleroderma 1.9
liver cancer 1.9
muscular dystrophy 1.9
uremia 1.9
mole 1.9
Adhesion 1.9
Bordetella 1.9
more...
Symptom
Anoxia 7.3
twitching 5.4
muscle stiffness 4.2
Wind 3.1
cerebellar ataxia 2.6
starvation 2.4
exhaustion 1.7
spasm 1.6
hypothermia 1.3
collapse 0.6
acidity 0.5
fatigue -0.2
seizures -0.9
anesthesia -2.3
pain -2.6
Drug
Coelenteramide 11.8
Flosequinan 9.7
Denopamine 9.2
CTZ 8.7
Pimobendan 8.3
Narcan 8.2
Fusicoccin 8.0
Deuterium oxide 7.9
C4H10 7.8
Levosimendan 7.7
Tranilast 6.7
Amrinone 6.6
Tubocurarine 6.5
caffeine 6.3
Palmitoyl 6.2
NovoSeven 6.1
Menthol 6.1
AC2 6.0
K-252a 6.0
Citric acid 5.4
Forskolin 5.4
Iloprost 5.4
Histamine 5.3
GHRP 5.3
Bupivacaine 4.8
TAT 4.8
CaCl2 4.6
CaCl2 4.6
CaCl2 4.6
CTC 4.4
PTH 4.3
CoCl2 4.1
CoCl2 4.1
Glucagon 4.1
Ouabain 4.1
Angiotensin II 4.1
CTC 4.1
balanced salt solution 3.8
Triclosan 3.8
Diurnal 3.7
Fructose 3.5
Theophylline 3.4
L-tyrosine 3.2
ROS 3.2
Ethanol 3.2
Fluorescein 3.0
ETA 3.0
NADH 2.8
Atropine 2.7
PCP 2.6
Fluorescein 2.5
niacin 2.5
nitroglycerin 2.3
Glutathione 2.0
CAM 1.9
Leaf 1.6
lysine 1.6
lactose 1.4
CTX 1.1
MAP 0.5
Cardiovasc 0.3
IL-2 -0.4
CSF -0.5
Enzyme
aequorin 14.4
acetate CoA-transferase 9.2
apyrase 7.0
beta-1,4-galactosyltransferase 6.7
polyphosphate kinase 6.6
calcium pump 6.4
GalT 6.3
myosin light chain kinase 6.2
diacylglycerol kinase 6.1
firefly luciferase 5.8
3C protease 5.5
ADPase 5.3
phospholipase C 5.1
glutathione synthetase 5.0
phosphatidylinositol 4-kinase 5.0
thrombin 4.8
TAT 4.8
phosphodiesterase 4.7
trehalase 4.6
Pla 4.6
luciferase 4.4
chaperonin 4.3
myosin ATPase 4.3
PKG 4.1
calcineurin 4.1
protein kinase C 4.0
gamma-glutamylcysteine synthetase 3.9
chalcone synthase 3.9
sialyltransferase 3.8
sialyltransferase 3.8
sialyltransferase 3.8
ATPase 3.8
PAL 3.8
pyruvate dehydrogenase 3.7
adenylate cyclase 3.7
pyruvate dehydrogenase 3.7
botulinum neurotoxin 3.5
NADPH oxidase 3.4
HIV-1 protease 3.4
PAL 3.4
glyceraldehyde-3-phosphate dehydrogenase 3.3
glyceraldehyde-3-phosphate dehydrogenase 3.3
complex I 3.3
NADPH oxidase 3.3
glyceraldehyde-3-phosphate dehydrogenase 3.2
phospholipase A2 3.2
pectinase 3.2
pyruvate dehydrogenase 3.0
glyceraldehyde-3-phosphate dehydrogenase 3.0
ascorbate peroxidase 3.0
glyceraldehyde-3-phosphate dehydrogenase 2.8
NOS 2.6
lactate dehydrogenase 2.6
PDE 2.6
PCP 2.5
phospholipase D 2.5
NO synthase 2.5
proteinase K 2.4
cholinesterase 2.4
guanylate cyclase 2.4
xylanase 2.4
chitinase 2.4
alkaline phosphatase 2.3
xylanase 2.3
malate dehydrogenase 2.3
CPR 2.1
protein kinase 2.0
peroxidase 2.0
phosphorylase 2.0
dihydrofolate reductase 1.9
phosphoinositide 3-kinase 1.9
diaphorase 1.9
cellulase 1.7
prostate-specific antigen 1.7
ATP synthase 1.6
caspase-9 1.5
beta-glucuronidase 1.5
APC 1.4
xanthine oxidase 1.4
DNA polymerase 1.4
more...
Compound
4-methoxyphenylalanine 12.4
4-methoxyphenylalanine 12.4
Inositol 1,3,4-trisphosphate 10.6
beta-Eudesmol 10.3
Decamethonium 10.1
1H-indole-2-carboxylic acid 9.4
3-ethylphenol 9.4
Oleandrin 9.2
Palmatine 8.5
D-600 8.4
Ryanodine 8.3
Cyclopiazonic acid 8.3
Dantrolene 8.1
Monocrotaline 7.9
Fusicoccin 7.9
DAM 7.7
Chloramine-T 7.5
Nisoldipine 7.5
Nicotinic acid adenine dinucleotide phosphate 7.4
Ionophore A23187 7.3
LNT 7.3
Nitrendipine 7.2
Mibefradil 7.0
Nicotinic acid adenine dinucleotide phosphate 7.0
Tubocurarine 6.6
12(S)-HETE 6.6
Carbachol 6.6
4-chlorobenzyl 6.6
DPI 6.5
Tetraethylammonium 6.4
Pinacidil 6.4
caffeine 6.3
BON 6.3
N-hydroxysuccinimide ester 6.3
Enflurane 6.2
calcium 6.2
Milrinone 6.2
Succinylcholine 6.1
Menthol 6.1
Mepyramine 6.1
Fluo-3 6.1
Inositol 6.1
Phorbol 12-myristate 13-acetate 6.0
Nocodazole 6.0
Menthol 6.0
1H-benzimidazole 6.0
Ins(1,4,5)P3 5.9
12-hydroxyeicosatetraenoic acid 5.8
TMB 5.8
Okadaic acid 5.7
2-naphthyl 5.7
Phencyclidine 5.6
Hearts 5.6
Phenylephrine 5.6
ETH 5.5
PDP 5.5
Leukotriene B4 5.4
Hypo 5.4
Sphingosine 1-phosphate 5.4
Ruthenium red 5.4
Forskolin 5.4
Quinine 5.3
pyrazine 5.3
Staurosporine 5.3
Biotin 5.3
Histamine 5.3
ECS 5.2
Carrageenan 5.2
Staurosporine 5.2
Hoe 5.2
Isoform 5.2
Hydralazine 5.2
Flavonoid 5.1
m-cresol 5.1
Halothane 5.1
8-Br-cGMP 5.1
Methylglyoxal 5.1
DCMU 5.0
Sphingosine 5.0
Phorbol 5.0
more...