Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.13.11.12 (lipoxygenase)
 8,696 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
lipoxygenase 8604
cyclooxygenase 2678
Sep 636
5-lipoxygenase 621
phospholipase A2 537
Mol 316
15-lipoxygenase 299
catalase 254
superoxide dismutase 244
12-lipoxygenase 237
LOX 233
peroxidase 209
cytochrome P450 203
COX-2 179
phospholipase 171
thrombin 150
cytochrome P-450 140
NMR 136
collagen 133
FPL 127
more...
Disease
cancer 388
tumor 327
atherosclerosis 167
asthma 153
carcinogenesis 128
ischemia 108
GSH 103
PAF 92
hypertension 91
diabetes 81
anaphylaxis 76
pertussis 68
SRS 64
cold 61
arthritis 55
psoriasis 53
leukemia 52
tumorigenesis 46
carcinoma 45
HHT 44
more...
Symptom
pain 87
seizures 18
acidity 16
diarrhea 15
erythema 14
spasm 10
collapse 10
analgesia 10
respiratory distress 8
starvation 6
cachexia 5
chills 5
anesthesia 5
hyperoxia 5
nausea 4
tremor 4
functional recovery 4
cough 4
anorexia 4
skin irritation 4
more...
Drug
Indomethacin 276
ascorbate 94
vitamin E 85
Dermatol 69
ROS 45
Histamine 37
Cardiovasc 36
EPA 34
NADH 33
lysine 27
IFN-gamma 22
ICI 21
IL-2 20
CSF 20
linolenate 18
Leaf 18
CaCl2 17
Vitamin E 16
CaCl2 16
CaCl2 16
more...
Enzyme
lipoxygenase 8696
phospholipase A2 658
15-lipoxygenase 304
peroxidase 302
protein kinase C 276
superoxide dismutase 266
catalase 260
12-lipoxygenase 258
thrombin 148
phospholipase C 136
xanthine oxidase 117
mitogen-activated protein kinase 98
glutathione peroxidase 94
lipase 90
protein kinase 86
ascorbate peroxidase 76
tyrosinase 67
guanylate cyclase 67
trypsin 63
acetylcholinesterase 62
more...
Compound
calcium 934
oxygen 765
Dec 628
PGE2 406
Arachidonic acid 398
Nordihydroguaiaretic acid 336
hydrogen 335
prostacyclin 317
sodium 306
water 303
acetate 287
iron 283
Indomethacin 276
DNA 267
Clin 265
LTC4 263
5-HETE 221
nitric oxide 219
12-hydroxyeicosatetraenoic acid 179
H2O2 148
more...