Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.12.99.6 (hydrogenase)
 3,482 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ferredoxin 302
Sep 235
membrane-bound 213
NAD 186
EPR 175
NADH 167
ATP 153
Chlamydomonas 145
Mol 141
CO2 136
cytochrome 135
oxidoreductase 129
reductase 116
NMR 97
H16 89
NADPH 72
polypeptide 69
NADP 67
PCC 61
cytochrome c 55
FMN 40
SDS 39
GTPase 37
ATPase 35
Gen 35
dimeric 35
FAD 33
cytochrome b 32
Pseudomonas 32
lactate dehydrogenase 32
NAD+ 31
ATP synthase 28
diaphorase 25
gut 24
superoxide dismutase 24
fused 23
alcohol dehydrogenase 23
GTP 22
NADH dehydrogenase 21
transcriptional activator 21
C2H2 20
flavoprotein 20
BBS 20
apoE 20
catalase 17
ACS 17
AMP 17
SCH 17
transcriptional regulator 16
pyruvate dehydrogenase 16
ubiquinone 16
NADP+ 14
membrane protein 14
methyltransferase 14
glutamate dehydrogenase 13
complex I) 13
quinone oxidoreductase 13
ADP 13
microsomal 13
S protein 12
delta 4 12
MR-1 12
B10 11
nov 11
ORF 10
unknown function 10
FDH 10
ESR 9
mer 9
alpha, beta 9
GDP 9
malate dehydrogenase 8
insulin 8
precursor protein 8
proton pump 8
thioredoxin 7
threonine 7
peroxidase 7
aldehyde dehydrogenase 7
TOF 7
short-chain acyl-CoA dehydrogenase 7
transmembrane protein 7
G20 7
cytochrome c oxidase 7
hormone receptor 6
LDH 6
HYD1 6
PNP 6
integral membrane protein 6
SOD 6
NO3 6
PEG 6
glutamine synthetase 6
ORF1 6
gamma, delta 5
Met 5
acetyl-CoA synthetase 5
acid phosphatase 5
glyceraldehyde-3-phosphate dehydrogenase 5
Net 5
NHC 5
phosphoenolpyruvate carboxykinase 5
pyruvate kinase 5
NADH diaphorase 5
tRNA 5
aconitase 5
phosphoenolpyruvate carboxylase 5
cytochrome P-450 5
myoglobin 4
alkaline phosphatase 4
decarboxylating 4
ABC 4
acetaldehyde dehydrogenase 4
ATP-binding cassette 4
lipopolysaccharide 4
C-terminal peptide 4
SAM 4
ECE 4
A. nidulans 4
ferritin 4
acylphosphatase 4
C-1 4
TCA 4
hexokinase 4
dilute 4
housekeeping 4
SRS 4
Alcohol dehydrogenase 4
lysozyme 4
COD 4
SHE 4
ORF4 4
Cytochrome c 4
serum albumin 4
endoprotease 4
MT1 4
SDHB 4
ABC transporter 4
glucose dehydrogenase 4
hemoglobin 3
glucose-6-phosphate dehydrogenase 3
DNA polymerase 3
ISP2 3
CYP1B1 3
heat shock protein 3
non-functional 3
TEM 3
B13 3
IscU 3
17 beta-hydroxysteroid dehydrogenase 3
Cytochrome b 3
histone 3
FADH2 3
IscS 3
K12 3
hole 3
glutathione peroxidase 3
cytochrome P450 3
NTP 3
phosphofructokinase 3
more...
Disease
PCC 63
pheochromocytoma 62
SDS 39
mole 23
mole 23
Klebsiella 23
NBS 20
Bardet-Biedl syndrome 20
SCH 17
Benson 13
FDH 10
Mycobacterium 8
Proteus 8
Frey 7
cancer 7
hypertension 7
cold 6
familial hemophagocytic lymphohistiocytosis 6
breast cancer 5
hepatocellular carcinoma 5
NHC 5
infectious diseases 5
suicide 4
diabetes 4
SRS 4
Evans 4
salmonellosis 3
typhoid 3
mimicry 3
dehydration 3
TEM 3
CAA 3
ICP 3
SEM 3
bends 3
VPI 3
Dissociation 3
emerging infectious disease 3
TEM 3
CAA 3
tumor 3
trichomoniasis 3
DES 3
hyperglycemia 3
hypercholesterolemia 2
RHE 2
enteritis 2
malnutrition 2
Ogo 2
gastritis 2
STD 2
Hodgson 2
Infection 2
Giant 2
PMS 2
premenstrual syndrome 2
alcoholism 2
PGA 2
tuberculosis 2
depression 2
cholera 2
carcinogenesis 2
CDS 2
West 2
atherosclerosis 2
meningoencephalitis 2
chronic hepatitis 2
ischemia 2
plaque 2
hepatitis 2
HP1 2
essential hypertension 2
hereditary spherocytosis 1
anemia 1
anemia of chronic disease 1
Blocking 1
complicated pregnancy 1
adenocarcinoma 1
Echinococcus 1
toxic shock syndrome 1
Fox 1
MCD 1
Shigella flexneri 1
Hippel 1
peptic ulcer 1
NAME 1
MBS 1
chlorosis 1
ADH 1
heart failure 1
Other variants 1
PDB 1
pseudohypoparathyroidism 1
medullary thyroid carcinoma 1
MAC 1
conversion reaction 1
dyslipidemia 1
Photosensitization 1
Yersinia 1
Haemophilus 1
sudden infant death syndrome 1
ventricular hypertrophy 1
sepsis 1
Fibrillation 1
hyperinsulinemia 1
type 2 diabetes 1
hyperlipidemia 1
gastroenteritis 1
hyperlipoproteinemia 1
carcinoma 1
polyarteritis nodosa 1
HYD2 1
osteosarcoma 1
hypernatremia 1
mastitis 1
addiction 1
fits 1
chemical carcinogenesis 1
ileus 1
HCI 1
RP4 1
urinary tract infection 1
Jensen 1
canker 1
Merkel cell carcinoma 1
Brucella suis 1
neurofibromatosis type 1 1
PAM 1
Diffuse idiopathic skeletal hyperostosis 1
drunk 1
bladder cancer 1
CCD 1
infertility 1
metabolic syndrome 1
cystic fibrosis 1
unstable angina 1
tularemia 1
acute renal failure 1
GSH 1
neurofibromatosis 1
Wiskott-Aldrich syndrome 1
melanoma 1
primary hyperoxaluria 1
PCP 1
glioblastoma multiforme 1
DIP 1
glioma 1
adaptation reaction 1
obesity 1
vagina 1
MTC 1
rheumatism 1
Age-related macular degeneration 1
periodontitis 1
hypersensitivity pneumonitis 1
Infections 1
iron overload 1
APL 1
NPC 1
iron deficiency 1
more...
Symptom
starvation 12
acidity 5
diarrhea 3
flushing 3
tremor 2
collapse 2
agitation 1
vomiting 1
anesthesia 1
exhaustion 1
exertional dyspnea 1
Drug
NADH 168
FAD 33
ascorbate 27
lysine 26
THF 16
PCB 11
Gel 10
TiO2 7
DMAP 6
Flavin 6
NH3 5
ABC 4
MAP 3
MOF 3
Glycerol 3
ROS 3
Heme 2
ampicillin 2
CoCl2 2
CoCl2 2
ZnCl2 2
Fructose 2
Glutathione 2
ZnO 2
Albumin 2
L-tyrosine 2
ALA 2
Ethanol 2
lactose 2
ZnCl2 2
Vitamin B12 1
Sandostatin 1
Fragment 1
Metrizamide 1
TAT 1
Glycyrrhiza 1
Sandostatin 1
PCP 1
Olmesartan 1
Arsenic trioxide 1
Itraconazole 1
FeCl3 1
nitroglycerin 1
citric acid 1
Leaf 1
Ethane 1
Ferric oxide 1
DNase I 1
-deoxyadenosine 1
MgSO4 1
Asn 1
Sinemet 1
MTC 1
CPM 1
CIA 1
Chlorate 1
Enzyme
hydrogenase 3482
hydrogenase 3482
nitrogenase 200
formate dehydrogenase 176
formate dehydrogenase 154
formate dehydrogenase 153
membrane-bound hydrogenase 83
urease 74
urease 73
complex I 61
diaphorase 53
pyruvate:ferredoxin oxidoreductase 42
nitrate reductase 40
CO dehydrogenase 40
nitrate reductase 40
nitrate reductase 40
nitrate reductase 40
nitrate reductase 40
nitrate reductase 40
bidirectional hydrogenase 38
ATPase 37
lactate dehydrogenase 33
alcohol dehydrogenase 32
heterodisulfide reductase 32
NQO1 29
succinic dehydrogenase 28
ACS 28
NADPH-diaphorase 28
fumarate reductase 26
ATP synthase 25
diaphorase 25
superoxide dismutase 25
NADH dehydrogenase 22
acetate kinase 21
pyruvate dehydrogenase 19
catalase 17
CD10 16
dissimilatory sulfite reductase 16
pyruvate dehydrogenase 16
pyruvate dehydrogenase 16
RNA polymerase 15
nitrite reductase 14
nitrite reductase 14
nitrite reductase 13
F420-reducing hydrogenase 12
EC 1.12.2.1 12
beta-galactosidase 12
sulfite reductase 11
sulfur reductase 11
trypsin 11
sulfite reductase 11
sulfite reductase 11
aldehyde dehydrogenase 11
succinate dehydrogenase 11
protein kinase 10
cytochrome oxidase 10
histidine kinase 9
PTA 9
glutamate dehydrogenase 9
glutamate dehydrogenase 9
methyl coenzyme M reductase 9
phosphoenolpyruvate carboxykinase 9
reverse transcriptase 9
glutamate dehydrogenase 9
phosphoenolpyruvate carboxykinase 9
phosphoenolpyruvate carboxykinase 8
malate dehydrogenase 8
peroxidase 8
aldehyde dehydrogenase 8
rubisco 8
aldehyde dehydrogenase 7
glucose-6-phosphate dehydrogenase 7
aldehyde dehydrogenase 7
aldehyde dehydrogenase 7
transhydrogenase 7
methylenetetrahydromethanopterin dehydrogenase 7
glyceraldehyde-3-phosphate dehydrogenase 7
butyryl-CoA dehydrogenase 7
butyrate kinase 7
acetyl-CoA synthetase 6
aconitase 6
TOR 6
PCE 6
glutamine synthetase 6
pyruvate formate-lyase 6
glyceraldehyde-3-phosphate dehydrogenase 6
ferredoxin reductase 6
superoxide reductase 5
methane monooxygenase 5
acid phosphatase 5
glyceraldehyde-3-phosphate dehydrogenase 5
alanine aminotransferase 5
glyceraldehyde-3-phosphate dehydrogenase 5
pyruvate kinase 5
TSR 5
coproporphyrinogen III oxidase 5
glyceraldehyde-3-phosphate dehydrogenase 5
peptidyl-prolyl cis-trans isomerase 4
phosphoenolpyruvate carboxylase 4
decarbonylase 4
alkaline phosphatase 4
glucose dehydrogenase 4
nitrous oxide reductase 4
lactate racemase 4
fumarase 4
NADPH oxidase 4
SCS 4
succinyl-CoA synthetase 4
NADPH oxidase 4
hexokinase 4
lysozyme 4
acylphosphatase 4
bilirubin oxidase 4
DNA polymerase 4
dihydroxyacetone kinase 3
glycerol dehydrogenase 3
xylanase 3
acyl-CoA dehydrogenase 3
arylsulfatase 3
glucose oxidase 3
glycerol dehydrogenase 3
ECH 3
glutathione peroxidase 3
aspartate aminotransferase 3
glycerol dehydratase 3
phosphofructokinase 3
HSD 3
E-2 3
formylmethanofuran dehydrogenase 3
CPR 3
xylanase 3
beta-glucuronidase 3
IscS 3
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase 3
cellulase 3
aldolase 3
11beta-hydroxysteroid dehydrogenase 3
demethylase 3
CYP3A4 3
acyl-CoA dehydrogenase 3
APS reductase 3
methanol dehydrogenase 3
endonuclease 3
acetoacetate decarboxylase 3
ALA synthase 3
citrate synthase 2
homocitrate synthase 2
xanthine dehydrogenase 2
benzoyl-CoA reductase 2
glycerol-3-phosphate dehydrogenase 2
thioredoxin reductase 2
gamma-glutamyl transpeptidase 2
sulfatase 2
carbonic anhydrase 2
alanine dehydrogenase 2
hydroxylamine reductase 2
isocitrate lyase 2
heme oxygenase 2
AOR 2
cyclohydrolase 2
more...
Compound
hydrogen 1368
iron 661
nickel 422
oxygen 395
CO2 340
water 270
Dec 249
nitrogen 226
NAD 216
DNA 194
sulfate 188
NAD 186
cysteine 176
NADH 168
acetate 161
ATP 153
glucose 152
cyanide 104
nitrate 101
His 100
NADP 98
sodium 97
ethanol 91
methane 84
phosphate 78
NADPH 72
NADPH 72
selenium 56
ammonia 55
ammonium 54
methanol 50
zinc 50
arginine 46
SDS 46
copper 45
glycerol 45
FMN 40
methionine 37
acetic acid 35
molybdenum 34
cobalt 34
FAD 33
nicotinamide 33
lysine 32
CoA 31
NH2 31
alanine 30
salt 30
Formate 30
DEAE 28
tyrosine 28
manganese 27
C2H2 27
adenosylmethionine 25
pyridine 24
alcohol dehydrogenase 24
H2S 24
DSM 23
H2S 23
urea 23
EDTA 23
EDTA 22
GTP 22
glutamate 21
acetyl-CoA 21
serine 19
acetonitrile 18
acetone 18
Ferredoxin 18
Triton X-100 18
Gly 17
ACS 17
ACS 17
ubiquinone 16
phenazine 16
AMP 16
CoM 16
2-oxoglutarate 15
PEG 15
threonine 15
Asp 15
DCMU 15
nitric oxide 15
aldehyde 14
MPT 14
tungsten 14
leucine 14
ADP 14
sulfuric acid 14
potassium 14
cadmium 14
toluene 13
ADP 13
DCC 13
Fumarate 13
ADP 13
formic acid 12
formaldehyde 12
formic acid 12
bromide 12
formic acid 12
formic acid 12
formic acid 12
formic acid 12
formic acid 12
formic acid 12
formic acid 12
Lactate 12
formic acid 12
THF 11
proline 11
Pyruvate 11
HCl 11
heptyl 11
heptyl 11
THF 10
MBH 10
acrylamide 10
tryptophan 10
hydroxylamine 10
NiCl2 10
Tris 10
Mg2+ 10
Carbon 10
tryptophan 10
tryptophan 10
tryptophan 10
DMF 9
aldehyde 9
butyric acid 9
Tris 9
benzene 9
GDP 9
formaldehyde 9
pentose 9
pentose 9
PEG 9
pentose 9
pentose 9
valine 9
BF4 8
DMSO 8
titanium 8
2-pyridinol 8
butyryl-CoA 8
hydroxylamine 8
2-mercaptoethanol 8
BF4 8
BF4 8
2-pyridinol 8
2-pyridinol 8
Nitrate 8
H4MPT 8
TOF 7
NIDA 7
acetaldehyde 7
Phe 7
G20 7
betaine 7
calcium 7
more...